Grants per year
Personal profile
Research Interests
Dr. Sachdev specializes in the treatment of brain and spine tumors (benign, malignant, or metastatic) as well as genitourinary (prostate and bladder) cancers. He is actively involved in translational research and bringing novel therapeutics to the clinic. He has an interest in synergistic approaches utilizing highly-conformal image-guided radiotherapy.
Central Nervous System: Dr. Sachdev focuses on benign and malignant brain tumors, brain metastases, spinal cord tumors and vascular lesions (AVMs). He has expertise in the use of GammaKnife/stereotactic radiosurgery (SRS), spine stereotactic radiotherapy (SABR/SBRT) and image-guided highly-conformal radiotherapy. Genitourinary: Dr. Sachdev focuses on prostate and bladder/urothelial cancers utilizing image-guided conformal dose-escalated radiotherapy for improved outcomes and better normal structure sparing. He has interest in the use of stereotactic radiotherapy (SABR/SBRT) for treatment of oligo-metastatic disease. He also maintains an interest in bladder preservation strategies that employ concurrent radiotherapy and chemotherapy in carefully selected patients.
Training Experience
2012 | Internship, University of California Medical Center, San Diego |
2016 | Residency, Northwestern University, McGaw Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Stanford University
… → 2011
Research interests keywords
- Acoustic Neuroma
- Bladder Cancer
- Brain Cancer / Nervous System Cancer
- Kidney Cancer / Urinary Tract Cancer
- Neuro-Oncology
- Prostate Cancer
- Radiation Oncology
- Spinal Cord Tumors
- Spinal Oncology
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Collaborations and top research areas from the last five years
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Project 1
Lesniak, M. S., Amidei, C. M., Chandler, J. P., Sachdev, S., Sonabend Worthalter, A. M. & Stupp, R.
8/1/23 → 7/31/28
Project: Research project
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A Phase II Clinical Trial in Newly Diagnosed Glioblastoma Patients Treated with WP1066 and Radiation
Heimberger, A. B., Kumthekar, P. U., Hill, V. B., Kocherginsky, M. & Sachdev, S.
5/5/23 → 4/30/28
Project: Research project
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SPORE for Translational Approaches to Brain Cancer
Lesniak, M. S., Chandler, J. P., Hu, B., Kumthekar, P. U., Leikin, R. G., Liu, B. P., Sachdev, S., Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Cheng, S., Horbinski, C. M., James, C. D., Lukas, R. V., Platanias, L. C., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.
8/17/18 → 7/31/23
Project: Research project
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SPORE for Translational Approaches to Brain Cancer
Lesniak, M. S., Chandler, J. P., Hu, B., Kumthekar, P. U., Leikin, R. G., Liu, B. P., Sachdev, S., Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Cheng, S., Horbinski, C. M., James, C. D., Lukas, R. V., Platanias, L. C., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.
8/17/18 → 7/31/23
Project: Research project
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Docetaxel targets aggressive methylation profiles and serves as a radiosensitizer in high-risk meningiomas
Youngblood, M. W., Tran, A. N., Wang, W., An, S., Scholtens, D., Zhang, L., O'Shea, K., Pokorny, J. L., Magill, S. T., Sachdev, S., Lukas, R. V., Ahmed, A., Unruh, D., Walshon, J., McCortney, K., Wang, Y., Baran, A., Sahm, F., Aldape, K., Chandler, J. P., & 3 others , Mar 14 2023, In: Neuro-oncology. 25, 3, p. 508-519 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Gene Therapy for High Grade Glioma: The Clinical Experience
Varela, M. L., Comba, A., Faisal, S. M., Argento, A., Franson, A., Barissi, M. N., Sachdev, S., Castro, M. G. & Lowenstein, P. R., 2023, In: Expert Opinion on Biological Therapy. 23, 2, p. 145-161 17 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
HER2+ esophageal carcinoma leptomeningeal metastases treated with intrathecal trastuzumab regimen
Wu, S. A., Jia, D. T., Schwartz, M., Mulcahy, M., Guo, K., Tate, M. C., Sachdev, S., Kostelecky, N., Escobar, D. J., Brat, D. J., Heimberger, A. B. & Lukas, R. V., May 23 2023, In: CNS oncology. 12, 3, CNS99.Research output: Contribution to journal › Article › peer-review
Open Access -
Radiosensitization of IDH-Mutated Gliomas through ZMYND8 - a Pathway to Improved Outcomes
Sachdev, S., Dmello, C. & Sonabend, A. M., May 1 2023, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 29, 9, p. 1648-1650 3 p.Research output: Contribution to journal › Editorial › peer-review
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Bladder-Sparing Approaches to Treatment of Muscle-Invasive Bladder Cancer
Bajaj, A. & Sachdev, S., Jan 1 2022, Urologic Oncology: Multidisciplinary Care for Patients. Springer International Publishing, p. 381-424 44 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter