Grants per year
Personal profile
Research Interests
I am a surgeon; my main professional goal is to provide surgical treatment for women with breast cancer, those at high risk for it, and those with benign breast problems. To deliver the best surgical care, I strive to help women with breast cancer and those with benign breast conditions understand their disease so that they will make informed treatment decisions that give them the best chance of cure with the best quality of life. In addition to treatment of breast diseases, I have a major clinical and research interest in understanding breast cancer risk and finding safe ways of preventing breast cancer so that I can accurately identify high risk women and help them make the decisions that will leave them with the lowest risk of breast cancer with the best quality of life.
Certifications and Licenses
| Surgery |
Training Experience
| 1982 | Residency, Saint Agnes Hospital |
| 1984 | Residency, Saint Joseph's Hospital |
| 1986 | Fellowship, Roswell Park Cancer Institute |
| 1989 | Fellowship, Roswell Park Cancer Institute |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Dow Medical College, Pakistan
… → 1978
Research interests keywords
- Breast Cancer
- Breast Disease
- Epidemiology
- Genetic Testing/Counseling
- Preventive Medicine
- Quality of Life
- Surgery
- Women's Health
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Preclinical and clinical studies of breast cancer prevention and with transdermal antiprogesterone agents
Khan, S. A. (PD/PI) & Lee, O. (Co-Investigator)
Breast Cancer Research Foundation
10/1/24 → 9/30/25
Project: Research project
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Suppression of progesterone receptor signaling by heavy metals promotes tamoxifen resistance and metastasis or ER+ breast cancer
Bonini, M. (PD/PI), Khan, S. A. (Co-Investigator) & Kocherginsky, M. (Co-Investigator)
National Institute of Environmental Health Sciences
6/24/24 → 3/31/29
Project: Research project
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H3 histone oxidation is a new posttranslational modification linking heavy metal-induced metabolic changes and oncegenic epigenetic reprogramming
Bonini, M. (PD/PI), Khan, S. A. (Co-Investigator) & Kocherginsky, M. (Co-Investigator)
National Institute of Environmental Health Sciences
1/23/24 → 10/31/28
Project: Research project
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Refining tamoxifen dose for premenopausal breast cancer prevention: RENAISSANCE, a Phase II trial
Khan, S. A. (PD/PI), LaBoy, C. (Co-Investigator) & Rao, S. S. (Co-Investigator)
Breast Cancer Research Foundation
10/1/23 → 9/30/26
Project: Research project
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A randomized Phase I pre-operative window trial of transdermal endoxifen in women planning mastectomy: Evaluation of dermal safety, intra-mammary drug distribution, and biologic effects
Lee, O., Bazzi, L. A., Xu, Y., Pearson, E., Wang, M., Hosseini, O., Akasha, A. M., Choi, J. N., Karlan, S., Pilewskie, M., Kocherginsky, M., Benante, K., Helland, T., Mellgren, G., Dimond, E., Perloff, M., Heckman-Stoddard, B. M. & Khan, S. A., Feb 2024, In: Biomedicine and Pharmacotherapy. 171, 116105.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment
Delaloge, S., Khan, S. A., Wesseling, J. & Whelan, T., Jun 22 2024, In: The Lancet. 403, 10445, p. 2734-2746 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system
Luo, Y., Mao, C., Sanchez-Pinto, L. N., Ahmad, F. S., Naidech, A., Rasmussen, L., Pacheco, J. A., Schneider, D., Mithal, L. B., Dresden, S., Holmes, K., Carson, M., Shah, S. J., Khan, S., Clare, S., Wunderink, R. G., Liu, H., Walunas, T., Cooper, L. & Yue, F. & 14 others, , Jul 2024, In: Learning Health Systems. 8, 3, e10417.Research output: Contribution to journal › Article › peer-review
Open Access -
The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB)
Rothschild, H. T., Clelland, E. N., Abel, M. K., Chien, A. J., Shui, A. M., Esserman, L., Khan, S. A. & Mukhtar, R. A., Jan 2024, In: Breast Cancer Research and Treatment. 203, 2, p. 245-256 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Author Correction: Lipid exposure activates gene expression changes associated with estrogen receptor negative breast cancer (npj Breast Cancer, (2022), 8, 1, (59), 10.1038/s41523-022-00422-0)
Yadav, S., Virk, R., Chung, C. H., Eduardo, M. B., VanDerway, D., Chen, D., Burdett, K., Gao, H., Zeng, Z., Ranjan, M., Cottone, G., Xuei, X., Chandrasekaran, S., Backman, V., Chatterton, R., Khan, S. & Clare, S. E., Dec 2023, In: npj Breast Cancer. 9, 1, 11.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Datasets
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Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5542078, https://springernature.figshare.com/collections/Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/5542078
Dataset
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Additional file 20 of Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.15102514, https://springernature.figshare.com/articles/dataset/Additional_file_20_of_Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/15102514
Dataset
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Additional file 22 of Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.15102520, https://springernature.figshare.com/articles/dataset/Additional_file_22_of_Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/15102520
Dataset
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Additional file 15 of Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.15102496, https://springernature.figshare.com/articles/dataset/Additional_file_15_of_Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/15102496
Dataset
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MOESM10 of BRCA1 mutation influences progesterone response in human benign mammary organoids
Davaadelger, B. (Contributor), Choi, M.-R. (Creator), Singhal, H. (Creator), Clare, S. E. (Creator), Khan, S. A. (Creator) & Kim, J. J. (Contributor), figshare, 2019
DOI: 10.6084/m9.figshare.11273291, https://springernature.figshare.com/articles/MOESM10_of_BRCA1_mutation_influences_progesterone_response_in_human_benign_mammary_organoids/11273291
Dataset