Seema Singhal

Professor, Medicine, Hematology Oncology Division
Chez Family Professor of Myeloma Research, Medicine, Hematology Oncology Division

Phone312/695-8697
Emails-singhal@northwestern.edu

Source: Scopus

Research output per year

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Personal profile

Research Interests

Myeloma, Transplantation

Certifications and Licenses

Internal Medicine

Training Experience

1991	Residency, Bombay University, India
1992	Fellowship, Hadassah University Hospital, Israel

Education/Academic qualification

MD, Bombay University

… → 1991

Research interests

Amyloidosis
Monoclonal Antibodies
Multiple Myeloma
Plasma Cell Disorders
Stem Cell Transplant
Waldenstroms

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4 Active
42 Finished

Prot #213304: Expanded Access Program for Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma Who are Refractory to a Proteasome Inhibitor, and an Immunomodulatory Agent, and an Anti-CD38 Antibody
Singhal, S.
Quintiles, Inc., GlaxoSmithKline LLC
3/11/20 → 3/11/23
Project: Research project
Prot #68284528MMY2003: A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA in Subjects with Multiple Myeloma (CARTITUDE-2)
Singhal, S.
Janssen Research & Development, LLC
2/11/20 → 2/11/23
Project: Research project
Prot #CC-92480-MM-002: A Phase 1/2, Multicenter, Open-label, Study to Determine the Recommended Dose and Regimen, and Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination with Standard Treatments in Subjects with Relapsed or Refractory
Singhal, S.
Celgene Corporation
11/14/19 → 11/14/22
Project: Research project
Prot #CC-220-MM-001: A Phase 1b/2a Multicenter, Open-label, Dose-escalation Study to Determine the Maximum Tolerated Dose, Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CC-220 Monotherapy and in Combination with Other Treatments in Sub
Singhal, S.
ICON Clinical Research, LLC, Celgene Corporation
10/10/19 → 10/10/22
Project: Research project
Prot #MK-3475-183: A phase III study of Pomalidomide and low dose Dexamethasone with or without Pembrolizumab (MK3475) in refractory or relapsed and refractory Multiple Myeloma (rrMM).
Singhal, S.
Merck Sharp & Dohme Corporation
1/26/17 → 1/26/20
Project: Research project

15365 Citations
181 Article
23 Review article
20 Letter
11 Comment/debate
More

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry
Du, Z., Weinhold, N., Song, G. C., Rand, K. A., Van Den Berg, D. J., Hwang, A. E., Sheng, X., Hom, V., Ailawadhi, S., Nooka, A. K., Singhal, S., Pawlish, K., Peters, E. S., Bock, C., Mohrbacher, A., Stram, A., Berndt, S. I., Blot, W. J., Casey, G., Stevens, V. L. & 50 others, Kittles, R., Goodman, P. J., Diver, W. R., Hennis, A., Nemesure, B., Klein, E. A., Rybicki, B. A., Stanford, J. L., Witte, J. S., Signorello, L., John, E. M., Bernstein, L., Stroup, A. M., Stephens, O. W., Zangari, M., Van Rhee, F., Olshan, A., Zheng, W., Hu, J. J., Ziegler, R., Nyante, S. J., Ingles, S. A., Press, M. F., Carpten, J. D., Chanock, S. J., Mehta, J., Colditz, G. A., Wolf, J., Martin, T. G., Tomasson, M., Fiala, M. A., Terebelo, H., Janakiraman, N., Kolonel, L., Anderson, K. C., Le Marchand, L., Auclair, D., Chiu, B. C. H., Ziv, E., Stram, D., Vij, R., Bernal-Mizrachi, L., Morgan, G. J., Zonder, J. A., Huff, C. A., Lonial, S., Orlowski, R. Z., Conti, D. V., Haiman, C. A. & Cozen, W., Jan 14 2020, In: Blood Advances. 4, 1, p. 181-190 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Variability in cytogenetic testing for multiple myeloma: a comprehensive analysis from across the United States
Yu, Y., Wade, N. B., Hwang, A. E., Nooka, A. K., Fiala, M. A., Mohrbacher, A., Peters, E. S., Pawlish, K., Bock, C., van Den, D. J., Rand, K. A., Stram, D., Conti, D. V., Auclair, D., Colditz, G. A., Mehta, J., Haiman, C. A., Terebelo, H., Janakiraman, N., Singhal, S. & 9 others, Chiu, B., Vij, R., Bernal-Mizrachi, L., Zonder, J. A., Huff, C. A., Lonial, S., Orlowski, R. Z., Cozen, W. & Ailawadhi, S., Oct 1 2020, In: JCO Oncology Practice. 16, 10, p. E1169-E1180
Research output: Contribution to journal › Article › peer-review
Multiple myeloma, version 1.2020 featured updates to the NCCN guidelines
Kumar, S. K., Callander, N. S., Hillengass, J., Liedtke, M., Baljevic, M., Campagnaro, E., Castillo, J. J., Chandler, J. C., Cornell, R. F., Costello, C., Efebera, Y., Faiman, M., Garfall, A., Godby, K., Holmberg, L., Htut, M., Huff, C. A., Kang, Y., Landgren, O., Malek, E. & 11 others, Martin, T., Omel, J., Raje, N., Sborov, D., Singhal, S., Stockerl-Goldstein, K., Tan, C., Weber, D., Johnson-Chilla, A., Keller, J. & Kumar, R., 2019, In: JNCCN Journal of the National Comprehensive Cancer Network. 17, 10, p. 1154-1165 12 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
25 Scopus citations
Pembrolizumab plus pomalidomide and dexamethasone for patients with relapsed or refractory multiple myeloma (KEYNOTE-183): a randomised, open-label, phase 3 trial
KEYNOTE-183 Investigators, Sep 2019, In: The Lancet Haematology. 6, 9, p. e459-e469
Research output: Contribution to journal › Article › peer-review
42 Scopus citations
Phase I study of the anti-FcRH5 antibody-drug conjugate DFRF4539A in relapsed or refractory multiple myeloma
Stewart, A. K., Krishnan, A. Y., Singhal, S., Boccia, R. V., Patel, M. R., Niesvizky, R., Chanan-Khan, A. A., Ailawadhi, S., Brumm, J., Mundt, K. E., Hong, K., McBride, J., Shon-Nguyen, Q., Xiao, Y., Ramakrishnan, V., Polson, A. G., Samineni, D., Leipold, D., Humke, E. W., McClellan, J. S. & 1 others, Berdeja, J. G., Feb 1 2019, In: Blood cancer journal. 9, 2, 17.
Research output: Contribution to journal › Article › peer-review
11 Scopus citations