Grants per year
Personal profile
Research Interests
Exploring the role of mitochondrial DNA in alveolar epithelial aging and lung diseases. - the epigenetic regulation of Klotho in cigarette smoke extract-induced lung epithelial cell DNA damage and lung diseases (e.g. lung fibrosis, COPD..). - the role of SIRT3 in maintaining AT2 cell mtDNA by preserving mt-OGG1/ ACO-2 function important for limiting AEC mitophagy defects, apoptosis and lung fibrosis.
Education/Academic qualification
PhD, Dong-A University
… → 2010
Research interests
- Aging
- DNA Repair
- Epigenetics
- Lung Injury
- Metabolism
- Molecular Biology
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Grants
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Epigenetic regulation of the Klotho / Miz 1 axis in smoking-induced emphysema.
Kalhan, R., Kamp, D. W., Kim, S., Liu, J. & Singer, B.
9/1/19 → 5/31/21
Project: Research project
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Research Output
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Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis
Kim, S. J., Cheresh, P., Jablonski, R. P., Rachek, L., Yeldandi, A., Piseaux-Aillon, R., Ciesielski, M. J., Ridge, K., Gottardi, C., Lam, A. P., Pardo, A., Selman, M., Natarajan, V. & Kamp, D. W., May 1 2020, In: American journal of physiology. Lung cellular and molecular physiology. 318, 5, p. L1084-L1096Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The sphingosine kinase 1 inhibitor, pf543, mitigates pulmonary fibrosis by reducing lung epithelial cell mtdna damage and recruitment of fibrogenic monocytes
Cheresh, P., Kim, S. J., Huang, L. S., Watanabe, S., Joshi, N., Williams, K. J. N., Chi, M., Lu, Z., Harijith, A., Yeldandi, A., Lam, A. P., Gottardi, C., Misharin, A. V., Budinger, G. R. S., Natarajan, V. & Kamp, D. W., 2020, In: International journal of molecular sciences. 21, 16, p. 1-17 17 p., 5595.Research output: Contribution to journal › Article › peer-review
Open Access -
Macrophages as a Source and Recipient of Wnt Signals
Malsin, E. S., Kim, S., Lam, A. P. & Gottardi, C. J., 2019, In: Frontiers in immunology. 10, p. 1813 1 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis
Suryadevara, V., Huang, L., Kim, S. J., Cheresh, P., Shaaya, M., Bandela, M., Fu, P., Feghali-Bostwick, C., Di Paolo, G., Kamp, D. W. & Natarajan, V., Aug 2019, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 2, p. L175-L187Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling
Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., Welch, L. C., Amarelle, L., Kim, S. J., Kaminski, N., Scott Budinger, G. R., Solway, J. & Sznajder, J. I., Sep 5 2018, In: Science translational medicine. 10, 457, aat1662.Research output: Contribution to journal › Article › peer-review
9 Scopus citations