Grants per year
Personal profile
Research Interests
Exploring the role of mitochondrial DNA in alveolar epithelial aging and lung diseases. - the epigenetic regulation of Klotho in cigarette smoke extract-induced lung epithelial cell DNA damage and lung diseases (e.g. lung fibrosis, COPD..). - the role of SIRT3 in maintaining AT2 cell mtDNA by preserving mt-OGG1/ ACO-2 function important for limiting AEC mitophagy defects, apoptosis and lung fibrosis.
Education/Academic qualification
PhD, Dong-A University
… → 2010
Research interests
- Aging
- DNA Repair
- Epigenetics
- Lung Injury
- Metabolism
- Molecular Biology
Fingerprint Dive into the research topics where Seokjo Kim is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 4 Similar Profiles
Alveolar Epithelial Cells
Medicine & Life Sciences
G(M3) Ganglioside
Medicine & Life Sciences
Mitochondrial DNA
Medicine & Life Sciences
Vascular Endothelial Growth Factor A
Medicine & Life Sciences
DNA Damage
Medicine & Life Sciences
Apoptosis
Medicine & Life Sciences
Pulmonary Fibrosis
Medicine & Life Sciences
Endothelial Cells
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2016 2021
Epigenetic regulation of the Klotho / Miz 1 axis in smoking-induced emphysema.
Kalhan, R., Kamp, D. W., Kim, S., Liu, J. & Singer, B.
9/1/19 → 5/31/21
Project: Research project
Emphysema
Mitochondrial DNA
Epigenomics
Smoking
Chronic Obstructive Pulmonary Disease
Asbestos
Alveolar Epithelial Cells
Veterans
Lung Diseases
Lung Neoplasms
Research Output 2005 2019
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis
Suryadevara, V., Huang, L., Kim, S., Cheresh, P., Shaaya, M., Bandela, M., Fu, P., Feghali-Bostwick, C., Di Paolo, G., Kamp, D. W. & Natarajan, V., Aug 1 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 2, p. L175-L187Research output: Contribution to journal › Article
Phospholipase D
Pulmonary Fibrosis
Mitochondrial DNA
DNA Damage
Reactive Oxygen Species
1
Citation
(Scopus)
Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling
Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., Welch, L. C., Amarelle, L., Kim, S., Kaminski, N., Budinger, GR. S., Solway, J. & Sznajder, J. I., Sep 5 2018, In : Science translational medicine. 10, 457, aat1662.Research output: Contribution to journal › Article
Caspase 7
Hypercapnia
MicroRNAs
Smooth Muscle
Chronic Obstructive Pulmonary Disease
2
Citations
(Scopus)
Insights into mineral fibre-induced lung epithelial cell toxicity and pulmonary fibrosis
Jablonski, R. P., Kim, S., Cheresh, P., Liu, G. & Kamp, D. W., Jan 1 2017, Mineral fibres: crystal chemistry, chemical-physical properties, biological interaction and toxicity, 2017. Mineralogical Society, Vol. 18. p. 447-500 54 p. (European Mineralogical Union Notes in Mineralogy; vol. 18).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Mineral Fibers
Asbestos
asbestos
Toxicity
toxicity
10
Citations
(Scopus)
Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis
Kim, S. J., Cheresh, P., Eren, M., Jablonski, R. P., Yeldandi, A., Ridge, K. M., Scott Budinger, G. R., Kim, D. H., Wolf, M., Vaughan, D. E. & Kamp, D. W., Jan 1 2017, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 1, p. L16-L26Research output: Contribution to journal › Article
Alveolar Epithelial Cells
Mitochondrial DNA
Oxidants
DNA Damage
Apoptosis
33
Citations
(Scopus)
ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis
Kim, Y. M., Kim, S., Tatsunami, R., Yamamura, H., Fukai, T. & Fukai, M. U., Jun 7 2017, In : American Journal of Physiology - Cell Physiology. 312, 6, p. C749-C764Research output: Contribution to journal › Article
Vascular Endothelial Growth Factor A
Reactive Oxygen Species
Mitochondria
Endothelial Cells
Phosphorylation