Seokjo Kim

  • 680 Citations
20052021
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Personal profile

Research Interests

Exploring the role of mitochondrial DNA in alveolar epithelial aging and lung diseases. - the epigenetic regulation of Klotho in cigarette smoke extract-induced lung epithelial cell DNA damage and lung diseases (e.g. lung fibrosis, COPD..). - the role of SIRT3 in maintaining AT2 cell mtDNA by preserving mt-OGG1/ ACO-2 function important for limiting AEC mitophagy defects, apoptosis and lung fibrosis.

Education/Academic qualification

PhD, Dong-A University

… → 2010

Research interests

  • Aging
  • DNA Repair
  • Epigenetics
  • Lung Injury
  • Metabolism
  • Molecular Biology

Fingerprint Dive into the research topics where Seokjo Kim is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Alveolar Epithelial Cells Medicine & Life Sciences
G(M3) Ganglioside Medicine & Life Sciences
Mitochondrial DNA Medicine & Life Sciences
Vascular Endothelial Growth Factor A Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Pulmonary Fibrosis Medicine & Life Sciences
Endothelial Cells Medicine & Life Sciences

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Grants 2016 2021

Emphysema
Mitochondrial DNA
Epigenomics
Smoking
Chronic Obstructive Pulmonary Disease

IPA for Seok-Jo Kim

Kamp, D. W. & Kim, S.

Jesse Brown VA Medical Center

11/1/169/30/18

Project: Research project

Asbestos
Alveolar Epithelial Cells
Veterans
Lung Diseases
Lung Neoplasms

Research Output 2005 2019

  • 680 Citations
  • 29 Article
  • 2 Review article
  • 1 Conference contribution

Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis

Suryadevara, V., Huang, L., Kim, S., Cheresh, P., Shaaya, M., Bandela, M., Fu, P., Feghali-Bostwick, C., Di Paolo, G., Kamp, D. W. & Natarajan, V., Aug 1 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 2, p. L175-L187

Research output: Contribution to journalArticle

Phospholipase D
Pulmonary Fibrosis
Mitochondrial DNA
DNA Damage
Reactive Oxygen Species
1 Citation (Scopus)

Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling

Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., Welch, L. C., Amarelle, L., Kim, S., Kaminski, N., Budinger, GR. S., Solway, J. & Sznajder, J. I., Sep 5 2018, In : Science translational medicine. 10, 457, aat1662.

Research output: Contribution to journalArticle

Caspase 7
Hypercapnia
MicroRNAs
Smooth Muscle
Chronic Obstructive Pulmonary Disease
2 Citations (Scopus)

Insights into mineral fibre-induced lung epithelial cell toxicity and pulmonary fibrosis

Jablonski, R. P., Kim, S., Cheresh, P., Liu, G. & Kamp, D. W., Jan 1 2017, Mineral fibres: crystal chemistry, chemical-physical properties, biological interaction and toxicity, 2017. Mineralogical Society, Vol. 18. p. 447-500 54 p. (European Mineralogical Union Notes in Mineralogy; vol. 18).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mineral Fibers
Asbestos
asbestos
Toxicity
toxicity
10 Citations (Scopus)
Alveolar Epithelial Cells
Mitochondrial DNA
Oxidants
DNA Damage
Apoptosis
33 Citations (Scopus)

ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis

Kim, Y. M., Kim, S., Tatsunami, R., Yamamura, H., Fukai, T. & Fukai, M. U., Jun 7 2017, In : American Journal of Physiology - Cell Physiology. 312, 6, p. C749-C764

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Reactive Oxygen Species
Mitochondria
Endothelial Cells
Phosphorylation