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Seokjo Kim

  • 866 Citations
20052020

Research output per year

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Personal profile

Research Interests

Exploring the role of mitochondrial DNA in alveolar epithelial aging and lung diseases. - the epigenetic regulation of Klotho in cigarette smoke extract-induced lung epithelial cell DNA damage and lung diseases (e.g. lung fibrosis, COPD..). - the role of SIRT3 in maintaining AT2 cell mtDNA by preserving mt-OGG1/ ACO-2 function important for limiting AEC mitophagy defects, apoptosis and lung fibrosis.

Education/Academic qualification

PhD, Dong-A University

… → 2010

Research interests

  • Aging
  • DNA Repair
  • Epigenetics
  • Lung Injury
  • Metabolism
  • Molecular Biology

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Grants

Epigenetic regulation of the Klotho / Miz 1 axis in smoking-induced emphysema.

Kalhan, R., Kamp, D. W., Kim, S., Liu, J. & Singer, B.

National Institute on Aging

9/1/19 → 5/31/21

Project: Research project

    • IPA for Seok-Jo Kim

    Kamp, D. W. & Kim, S.

    Jesse Brown VA Medical Center

    11/1/16 → 9/30/18

    Project: Research project

    • Research Output

    • 866 Citations
    • 29 Article
    • 3 Review article
    • 1 Conference contribution

    Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis

    Kim, S., Cheresh, P., Jablonski, R. P., Rachek, L., Yeldandi, A., Piseaux-Aillon, R., Ciesielski, M. J., Ridge, K., Gottardi, C., Lam, A. P., Pardo, A., Selman, M., Natarajan, V. & Kamp, D. W., May 1 2020, In : American journal of physiology. Lung cellular and molecular physiology. 318, 5, p. L1084-L1096

    Research output: Contribution to journal › Article

    Open Access

    • Macrophages as a Source and Recipient of Wnt Signals

    Malsin, E. S., Kim, S., Lam, A. P. & Gottardi, C. J., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

    Research output: Contribution to journal › Review article

    Open Access
    • 3 Scopus citations

    Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis

    Suryadevara, V., Huang, L., Kim, S. J., Cheresh, P., Shaaya, M., Bandela, M., Fu, P., Feghali-Bostwick, C., Di Paolo, G., Kamp, D. W. & Natarajan, V., Aug 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 2, p. L175-L187

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling

    Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., Welch, L. C., Amarelle, L., Kim, S. J., Kaminski, N., Scott Budinger, G. R., Solway, J. & Sznajder, J. I., Sep 5 2018, In : Science translational medicine. 10, 457, aat1662.

    Research output: Contribution to journal › Article

    • 5 Scopus citations

    Insights into mineral fibre-induced lung epithelial cell toxicity and pulmonary fibrosis

    Jablonski, R. P., Kim, S., Cheresh, P., Liu, G. & Kamp, D. W., Jan 1 2017, Mineral fibres: crystal chemistry, chemical-physical properties, biological interaction and toxicity, 2017. Mineralogical Society, Vol. 18. p. 447-500 54 p. (European Mineralogical Union Notes in Mineralogy; vol. 18).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

    • 4 Scopus citations