Shunyou Gong

  • 776 Citations
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Personal profile

Research Interests

My clinical duties at the Lurie Children’s Hospital of Chicago include signing out bone marrow and lymph node pathology reports, and directorship of the clinical hematology laboratory. My research interests are focused on the diagnosis, therapy, and pathogenesis of pediatric hematopoietic malignancies. We have recently identified that CD317 may serve as a marker for B-lymphoblastic leukemia/lymphoma (B-ALL) minimal residual disease detection, and I am looking further into the biological significance of loss of CD317 in leukemic blasts, and potential values in therapy and monitoring of disease progression. Additionally, we are collaborating with several groups to study the functional genomics of pediatric variant of follicular lymphoma, a newly-identified entity with little similarity to its adult counterparts. We have found that some genes encoding key regulatory proteins of multiple signaling pathways, particularly not shared by regular follicular lymphomas, are mutated in pediatric follicular lymphoma. We are interested in investigating how the mutant proteins change the behavior of transformed cells, and whether the knowledge we attain may benefit the laboratory diagnosis and clinical management of this unique type of pediatric lymphoma.

Training Experience

2006Postdoctoral Fellowship, University of Pennsylvania
2013Residency, Case Western Reserve University Hospital
2015Fellowship, National Institutes of Health

Education/Academic qualification

PhD, Peking University

… → 2001

MD, Hebei Medical College, P.R. China

… → 1995

Research interests

  • Pathology

Fingerprint Dive into the research topics where Shunyou Gong is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Thymocytes Medicine & Life Sciences
Natural Killer T-Cells Medicine & Life Sciences
Proteins Medicine & Life Sciences
Macrophages Medicine & Life Sciences
Chemokines Medicine & Life Sciences
Follicular Lymphoma Medicine & Life Sciences
Human Herpesvirus 4 Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences

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Research Output 2000 2019

  • 776 Citations
  • 24 Article
  • 1 Comment/debate

Myeloid neoplasm with germline predisposition: A 2016 update for pathologists

Gao, J., Gong, S. & Chen, Y-H., Jan 1 2019, In : Archives of pathology & laboratory medicine. 143, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Information Storage and Retrieval
Myelodysplastic Syndromes
Hematologic Neoplasms
1 Citation (Scopus)

Bone marrow histopathologic findings in SIFD syndrome: Beyond the erythroid lineage

Mariani, R. & Gong, S., Sep 27 2018, In : Blood. 132, 13, 1 p.

Research output: Contribution to journalComment/debate

Bone Marrow
1 Citation (Scopus)

Expanding the Spectrum of EBV-positive Marginal Zone Lymphomas: A Lesion Associated With Diverse Immunodeficiency Settings

Gong, S., Crane, G. M., McCall, C. M., Xiao, W., Ganapathi, K. A., Cuka, N., Davies-Hill, T., Xi, L., Raffeld, M., Pittaluga, S., Duffield, A. S. & Jaffe, E. S., Jun 27 2018, (Accepted/In press) In : American Journal of Surgical Pathology. 42, 10, p. 1306-1316 11 p.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Lymphoproliferative Disorders
Immunoglobulin Genes
2 Citations (Scopus)

Genome-wide analysis reveals TNFAIP8L2 as an immune checkpoint regulator of inflammation and metabolism

Li, T., Wang, W., Gong, S., Sun, H., Zhang, H., Yang, A. G., Chen, Y. H. & Li, X., Jul 1 2018, In : Molecular Immunology. 99, p. 154-162 9 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
1 Citation (Scopus)

Classical Hodgkin lymphoma and Castleman disease: A rare morphologic combination

Gong, S. & Hijiya, N., Jul 20 2017, In : Blood. 130, 3, 1 p.

Research output: Contribution to journalArticle