Simone Trieger Sredni

  • 771 Citations
19972021

Research output per year

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Research Output

  • 771 Citations
  • 47 Article
  • 7 Letter
  • 2 Comment/debate
2019

Evaluation of protein kinase inhibitors with plk4 cross-over potential in a pre-clinical model of cancer

Suri, A., Bailey, A. W., Tavares, M. T., Gunosewoyo, H., Dyer, C. P., Grupenmacher, A. T., Piper, D. R., Horton, R. A., Tomita, T., Kozikowski, A. P., Roy, S. M. & Sredni, S. T., May 1 2019, In : International journal of molecular sciences. 20, 9, 2112.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors

Malchenko, S., Sredni, S. T., Boyineni, J., Bi, Y., Margaryan, N. V., Guda, M. R., Kostenko, Y., Tomita, T., Davuluri, R. V., Velpula, K., Hendrix, M. J. C. & Soares, M. B., Jan 1 2018, In : Oncotarget. 9, 17, p. 13733-13747 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Polo-like kinase 4 (PLK4) is overexpressed in central nervous system neuroblastoma (CNS-NB)

Bailey, A. W., Suri, A., Chou, P. M., Pundy, T., Gadd, S., Raimondi, S. L., Tomita, T. & Sredni, S. T., Dec 2018, In : Bioengineering. 5, 4, 96.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain

Sredni, S. T., Suzuki, M., Yang, J. P., Topczewski, J., Bailey, A. W., Gokirmak, T., Gross, J. N., de Andrade, A., Kondo, A., Piper, D. R. & Tomita, T., Nov 2017, In : Pediatric Blood and Cancer. 64, 11, e26551.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition of polo-like kinase 4 (PLK4): A new therapeutic option for rhabdoid tumors and pediatric medulloblastoma

Sredni, S. T., Bailey, A. W., Suri, A., Hashizume, R., He, X., Louis, N., Gokirmak, T., Piper, D. R., Watterson, D. M. & Tomita, T., Jan 1 2017, In : Oncotarget. 8, 67, p. 111190-111212 23 p.

Research output: Contribution to journalArticle

8 Scopus citations

Overexpression of TEAD4 in atypical teratoid/rhabdoid tumor: New insight to the pathophysiology of an aggressive brain tumor

Suzuki, M., Kondo, A., Ogino, I., Arai, H., Tomita, T. & Sredni, S. T., Jul 1 2017, In : Pediatric Blood and Cancer. 64, 7, e26398.

Research output: Contribution to journalArticle

4 Scopus citations

Stabilization of HIF-1α and HIF-2α, upregulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model

Malchenko, S., Sredni, S. T., Bi, Y., Margaryan, N. V., Boyineni, J., Mohanam, I., Tomita, T., Davuluri, R. V. & Soares, M. B., Mar 2017, In : PloS one. 12, 3, e0173106.

Research output: Contribution to journalArticle

1 Scopus citations

The polo-like kinase 4 gene (PLK4) is overexpressed in pediatric medulloblastoma

Sredni, S. T. & Tomita, T., Jul 1 2017, In : Child's Nervous System. 33, 7, 1 p.

Research output: Contribution to journalLetter

7 Scopus citations
2016

Extensive miRNA expression analysis in craniopharyngiomas

Samis, J., Vanin, E. F., Sredni, S. T., de Bonaldo, M. D. F., Costa, F. F., Tomita, T., Habiby, R., Zimmerman, D. & Soares, M. B., Sep 1 2016, In : Child's Nervous System. 32, 9, p. 1617-1624 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

MicroRNA-10a regulation of proinflammatory mediators: An important component of untreated juvenile dermatomyositis

Xu, D., Huang, C. C., Kachaochana, A., Morgan, G. A., Bonaldo, M. F., Soares, M. B., Costa, F., Sarwark, J., Sredni, S. T. & Pachman, L. M., Jan 2016, In : Journal of Rheumatology. 43, 1, p. 161-168 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
7 Scopus citations
2015

A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells

Malchenko, S., Sredni, S. T., Hashimoto, H., Kasai, A., Nagayasu, K., Xie, J., Margaryan, N. V., Seiriki, K., Lulla, R. R., Seftor, R. E. B., Pachman, L. M., Meltzer, H. Y., Hendrix, M. J. C. & Soares, M. B., Mar 31 2015, In : PloS one. 10, 3, e0121707.

Research output: Contribution to journalArticle

4 Scopus citations

Atypical teratoid rhabdoid tumors of the posterior fossa in children

DiPatri, A. J., Sredni, S. T., Grahovac, G. & Tomita, T., Oct 13 2015, In : Child's Nervous System. 31, 10, p. 1717-1728 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Rhabdoid tumor predisposition syndrome

Sredni, S. T. & Tomita, T., Jan 1 2015, In : Pediatric and Developmental Pathology. 18, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

52 Scopus citations
2014

Activation of ErbB2- ErbB3 signaling pathway supports potential therapeutic activity of ErbB inhibitors in AT/RT

Sredni, S. T., Patel, K., Costa, F. D. A., De Fátima Bonaldo, M. & Tomita, T., May 2014, In : Journal of Neuro-Oncology. 118, 1, p. 201-203 3 p.

Research output: Contribution to journalLetter

4 Scopus citations

A gene signature for a long-term survivor of an atypical teratoid/rhabdoid tumor

Sredni, S. T., Huang, C. C., Pundy, T., Patel, K., Halpern, A. L., Grupenmacher, A. T., Chou, P. M., Bonaldo, M. D. F. & Tomita, T., Sep 1 2014, In : Cancer Genetics. 207, 9, p. 420-424 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Histone deacetylases expression in atypical teratoid rhabdoid tumors

Sredni, S. T., Halpern, A. L., Hamm, C. A., Bonaldo, M. D. F. & Tomita, T., Jan 1 2013, In : Child's Nervous System. 29, 1, p. 5-9 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Study of the gene expression and microRNA expression profiles of malignant rhabdoid tumors originated in the brain (AT/RT) and in the kidney (RTK)

Grupenmacher, A. T., Halpern, A. L., Bonaldo, M. D. F., Huang, C. C., Hamm, C. A., De Andrade, A., Tomita, T. & Sredni, S. T., Nov 1 2013, In : Child's Nervous System. 29, 11, p. 1977-1983 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012
22 Scopus citations

Methylation alterations of WT1 and homeobox genes in inflamed muscle biopsy samples from patients with untreated juvenile dermatomyositis suggest self-renewal capacity

Wang, M., Xie, H., Shrestha, S., Sredni, S. T., Morgan, G. A. & Pachman, L. M., Oct 1 2012, In : Arthritis and rheumatism. 64, 10, p. 3478-3485 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2011

A parallel study of mrna and microrna profiling of peripheral blood in young adult women

Sredni, S. O. T., Gadd, S., Jafari, N. & Huang, C. C., Dec 1 2011, In : Frontiers in Genetics. 2, JULY, Article 49.

Research output: Contribution to journalArticle

19 Scopus citations

Identification of micrornas as potential prognostic markers in ependymoma

Costa, F. F., Bischof, J. M., Vanin, E. F., Lulla, R. R., Wang, M., Sredni, S. T., Rajaram, V., de Fátima Bonaldo, M., Wang, D., Goldman, S., Tomita, T. & Soares, M. B., Nov 2 2011, In : PloS one. 6, 10, e25114.

Research output: Contribution to journalArticle

86 Scopus citations

Low prevalence of HPV in Brazilian children with retinoblastoma

Antoneli, C. B. G., Ribeiro, K. B., Sredni, S. T., Arias, V. E. A., Andreoli, M. A., De Camargo, B., Sobrinho, J. S., Prado, J. C. M., Soares, F. A. & Villa, L. L., Jan 1 2011, In : Journal of Medical Virology. 83, 1, p. 115-118 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

MicroRNA expression profiling for Molecular Classification of pediatric brain tumors

Sredni, S. T., Huang, C. C., Bonaldo, M. D. F. & Tomita, T., Jul 15 2011, In : Pediatric Blood and Cancer. 57, 1, p. 183-184 2 p.

Research output: Contribution to journalLetter

9 Scopus citations
2010

Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

Hamm, C. A., Stevens, J. W., Xie, H., Vanin, E. F., Morcuende, J. A., Abdulkawy, H., Seftor, E. A., Sredni, S. T., Bischof, J. M., Wang, D., Malchenko, S., de Fatima Bonaldo, M., Casavant, T. L., Hendrix, M. J. C. & Soares, M. B., Sep 1 2010, In : BMC Cancer. 10, 471.

Research output: Contribution to journalArticle

25 Scopus citations

Rhabdoid tumor: Gene expression clues to pathogenesis and potential therapeutic targets

Gadd, S., Sredni, S. T., Huang, C. C. & Perlman, E. J., May 1 2010, In : Laboratory Investigation. 90, 5, p. 724-738 15 p.

Research output: Contribution to journalArticle

58 Scopus citations

Upregulation of mir-221 and mir-222 in atypical teratoid/rhabdoid tumors: Potential therapeutic targets

Sredni, S. T., Bonaldo, M. D. F., Costa, F. F., Huang, C. C., Hamm, C. A., Rajaram, V., Tomita, T., Goldman, S., Bischof, J. M. & Soares, M. B., Jan 1 2010, In : Child's Nervous System. 26, 3, p. 279-283 5 p.

Research output: Contribution to journalArticle

22 Scopus citations
2009

An experimental brainstem tumor model using in vivo bioluminescence imaging in rat

Kondo, A., Goldman, S., Vanin, E. F., Sredni, S. T., Rajaram, V., Soares, M. B. & Tomita, T., May 1 2009, In : Child's Nervous System. 25, 5, p. 527-533 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Global demethylation of rat chondrosarcoma cells after treatment with 5-Aza-2′-deoxycytidine results in increased tumorigenicity

Hamm, C. A., Xie, H., Costa, F. F., Vanin, E. F., Seftor, E. A., Sredni, S. T., Bischof, J., Wang, D., Bonaldo, M. F., Hendrix, M. J. C. & Soares, M. B., Dec 1 2009, In : PloS one. 4, 12, e8340.

Research output: Contribution to journalArticle

39 Scopus citations

Interstitial continuous infusion therapy in a malignant glioma model in rats

Tange, Y., Kondo, A., Egorin, M. J., Mania-Farnell, B., Daneriallis, G. M., Nakazaki, H., Sredni, S. T., Rajaram, V., Goldman, S., Soares, M. B. & Tomita, T., Jun 1 2009, In : Child's Nervous System. 25, 6, p. 655-662 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Longitudinal assessment of regional directed delivery in a rodent malignant glioma model: Laboratory investigation

Kondo, A., Goldman, S., Lulla, R. R., Mania-Farnell, B., Vanin, E. F., Sredni, S. T., Rajaram, V., Soares, M. B. & Tomita, T., Dec 1 2009, In : Journal of Neurosurgery: Pediatrics. 4, 6, p. 592-598 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Predicting relapse in favorable histology wilms tumor using gene expression analysis: A report from the renal tumor committee of the children's oncology group

Huang, C. C., Gadd, S., Breslow, N., Cutcliffe, C., Sredni, S. T., Helenowski, I. B., Dome, J. S., Grundy, P. E., Green, D. M., Fritsch, M. K. & Perlman, E. J., Mar 1 2009, In : Clinical Cancer Research. 15, 5, p. 1770-1778 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Subsets of very low risk Wilms tumor show distinctive gene expression, histologic, and clinical features

Sredni, S. T., Gadd, S., Huang, C. C., Breslow, N., Grundy, P., Green, D. M., Dome, J. S., Shamberger, R. C., Beckwith, J. B. & Perlman, E. J., Nov 15 2009, In : Clinical Cancer Research. 15, 22, p. 6800-6809 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Texture image analysis in differentiating malignant from benign adrenal cortical tumors in children and adults

Shirata, N. K., Sredni, S. T., Castelo, A., Santinelli, A., Mendonça, B., Montironi, R., Longatto Filho, A. & Zerbini, M. C. N., Aug 1 2009, In : Anticancer Research. 29, 8, p. 3365-3368 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
2008

Molecular profiling of isolated histological components of Wilms tumor implicates a common role for the Wnt signaling pathway in kidney and tumor development

Maschietto, M., De Camargo, B., Brentani, H., Grundy, P., Sredni, S. T., Torres, C., Mota, L. D., Cunha, I. W., Patrão, D. F. C., Costa, C. M. L., Soares, F. A., Brentani, R. R. & Carraro, D. M., Sep 1 2008, In : ONCOLOGY. 75, 1-2, p. 81-91 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
2006

Childhood carcinoid tumors: Description of a case series in a Brazilian cancer center

Neves, G. R., Chapchap, P., Sredni, S. T., Viana, C. R. & Mendes, W. L., Jan 1 2006, In : Sao Paulo Medical Journal. 124, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Hepatoblastomas and liver development: A study of cytokeratin immunoexpression in twenty-nine hepatoblastomas

Cajaiba, M. M., Neves, J. I., Casarotti, F. F., De Camargo, B., ChapChap, P., Sredni, S. T. & Soares, F. A., May 1 2006, In : Pediatric and Developmental Pathology. 9, 3, p. 196-202 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hyperplastic perilobar nephroblastomatosis: Long-term survival of 52 patients

Perlman, E. J., Faria, P., Soares, A., Hoffer, F., Sredni, S., Ritchey, M., Shamberger, R. C., Green, D. & Beckwith, J. B., Feb 1 2006, In : Pediatric Blood and Cancer. 46, 2, p. 203-221 19 p.

Research output: Contribution to journalArticle

45 Scopus citations
2004

Endodermal Sinus Tumor of the Parotid Gland in a Child

Sredni, S. T., Da Cunha, I. W., De Carvalho Filho, N. P., Magrin, J., Lopes Pinto, C. A. & Lopes, L. F., Jan 1 2004, In : Pediatric and Developmental Pathology. 7, 1, p. 77-80 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Letter to the editor [1] (multiple letters)

Sredni, S. T., Maschieto, M., De Camargo, B., Soares, F. A., Fukuzawa, R., Heathcott, R. W., Morison, I. M., Reeve, A. E. & Sano, M., Dec 1 2004, In : Pediatric and Developmental Pathology. 7, 6, p. 668-670 3 p.

Research output: Contribution to journalLetter

Myogenesis in Wilms tumors.

Sredni, S. T., Maschieto, M., de Camargo, B. & Soares, F. A., Nov 1 2004, In : Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 7, 6

Research output: Contribution to journalComment/debate

2 Scopus citations

Pan-cytokeratin immunoexpression in Wilms' tumors: A simple approach for understanding tumor epithelial differentiation

Sredni, S. T., Neves, J. I., de Camargo, B., Damas de Caballero, O. L. & Soares, F. A., Jul 1 2004, In : Sao Paulo Medical Journal. 122, 4, p. 181-183 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2003

Adrenocortical tumours in children and adults: A study of pathological and proliferation features

Sredni, S. T., Ferreira Alves, V. A., Rosário Latorre, M. D. & Nogueira Zerbini, M. C., Apr 2003, In : Pathology. 35, 2, p. 130-135 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
1 Scopus citations

Extenso meningioma atípico na infância: Relato de caso

Translated title of the contribution: A large atypical meningioma in childhood: Case reportRondinelli, P. I. P., Viana, C. R., Osório, C. A. M. & Sredni, S. T., Sep 1 2003, In : Arquivos de Neuro-Psiquiatria. 61, 3 A, p. 695-698 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

p53 as a prognostic factor in adrenocortical tumors of adults and children

Sredni, S. T., Zerbini, M. C. N., Latorre, M. R. & Alves, V. A. F., Jan 1 2003, In : Brazilian Journal of Medical and Biological Research. 36, 1, p. 23-27 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2001

Immunohistochemical detection of p53 protein expression as a prognostic indicator in wilms tumor

Sredni, S. T., de Camargo, B., Lopes, L. F., Teixeira, R. & Simpson, A., Jan 1 2001, In : Medical and Pediatric Oncology. 37, 5, p. 455-458 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Recommendations for reporting of tumors of the adrenal cortex and medulla [1]

Sredni, S. T. & Zerbini, M. C. N., Jan 1 2000, In : Modern Pathology. 13, 8, 1 p.

Research output: Contribution to journalLetter

1999

Endodermal sinus tumor of the vagina in children

Lopes, L. F., Chazan, R., Sredni, S. T. & De Camargo, B., May 1 1999, In : Medical and Pediatric Oncology. 32, 5, p. 377-381 5 p.

Research output: Contribution to journalArticle

17 Scopus citations