Stephanie M Rangel

  • 150 Citations
20142021
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Personal profile

Research Interests

Director of the Clinical Trials Unit in Dermatology The Department of Dermatology conducts intensive clinical research focusing on the prevention, diagnosis, quality of life, and treatment of numerous dermatological conditions. Clinical research within the department falls under the Clinical Trials Unit (CTU). The CTU within the Department of Dermatology is composed of 25 members that provide an infrastructure for the management of clinical trials. This infrastructure includes a Director, a Research Assistant Professor, Physician Research Fellows (Clinical Research Associates), Study Coordinators, Research Assistants, Medical Student Research Fellows, and a Financial Project Manager and Financial Assistant. The unit accomplishes oversight for all aspects of clinical research including staffing, training, regulatory oversight, protocol design and start-up, and compliance issues.

Over 20 academic dermatologists and research faculty are engaged in clinical research at both Northwestern Memorial Hospital and Ann & Robert H. Lurie Children’s Hospital. Our projects span many diverse areas of research including but not limited to bioengineering, genetics/epigenomics and biomarkers, immunology, microbiome, patient reported outcomes, epidemiology, oncodermatology, and cutaneous imaging. The Clinical Trials Unit also oversees the Tissue Acquisition Program of the Northwestern University Skin Disease Research Center. The Tissue Acquisition Program provides biospecimens without identifiers to qualified investigators for skin biology research purposes on the Northwestern campus, but also to outside academic institutions and industry companies. The Clinical Trials Unit also supports two clinical research fellowships within the department, one for MD graduates and one for current medical students who have an interest in dermatology research.

Education/Academic qualification

PhD, Northwestern University Feinberg School of Medicine

… → 2014

Research interests

  • Adverse Drug Reactions
  • Biologic Therapies
  • Clinical Research
  • Clinical Trial Methodology
  • Dermatology
  • Microbiome
  • Quality of Life
  • Translational Research

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  • 3 Similar Profiles
Pseudomonas aeruginosa Medicine & Life Sciences
Atopic Dermatitis Medicine & Life Sciences
Pneumonia Medicine & Life Sciences
ADP Ribose Transferases Medicine & Life Sciences
T-cells Chemical Compounds
Skin Medicine & Life Sciences
Drug-Related Side Effects and Adverse Reactions Medicine & Life Sciences
Lung Medicine & Life Sciences

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Grants 2018 2021

Research Output 2014 2019

  • 150 Citations
  • 13 Article
  • 3 Review article
  • 2 Letter
  • 1 Comment/debate
4 Citations (Scopus)

Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients

Brunner, P. M., Israel, A., Leonard, A., Pavel, A. B., Kim, H. J., Zhang, N., Czarnowicki, T., Patel, K., Murphrey, M., Ramsey, K., Rangel, S. M., Zebda, R., Soundararajan, V., Zheng, X., Estrada, Y. D., Xu, H., Krueger, J. G., Paller, A. & Guttman-Yassky, E., Mar 1 2019, In : Annals of Allergy, Asthma and Immunology. 122, 3, p. 318-330.e3

Research output: Contribution to journalArticle

Atopic Dermatitis
Pediatrics
Skin
Interleukin-13
Biomarkers
1 Citation (Scopus)
Open Access
Spironolactone
Hyperkalemia
Acne Vulgaris
Drug-Related Side Effects and Adverse Reactions
Retrospective Studies
1 Citation (Scopus)

The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease

Brunner, P. M., He, H., Pavel, A. B., Czarnowicki, T., Lefferdink, R., Erickson, T., Canter, T., Puar, N., Rangel, S. M., Malik, K., Estrada, Y., Krueger, J. G., Guttman-Yassky, E. & Paller, A., Aug 1 2019, In : Journal of the American Academy of Dermatology. 81, 2, p. 510-519 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Proteomics
Pediatrics
Inflammation
Blood Proteins
4 Citations (Scopus)

The convergence theory for vitiligo: A reappraisal

Kundu, R. V., Mhlaba, J. M., Rangel, S. M. & Le Poole, I. C., Jun 1 2019, In : Experimental Dermatology. 28, 6, p. 647-655 9 p.

Research output: Contribution to journalReview article

Open Access
Vitiligo
T-cells
Skin
Radiation
Melanocytes
1 Citation (Scopus)

Use of Tape Strips to Detect Immune and Barrier Abnormalities in the Skin of Children with Early-Onset Atopic Dermatitis

Guttman-Yassky, E., Diaz, A., Pavel, A. B., Fernandes, M., Lefferdink, R., Erickson, T., Canter, T., Rangel, S., Peng, X., Li, R., Estrada, Y., Xu, H., Krueger, J. G. & Paller, A. S., Jan 1 2019, (Accepted/In press) In : JAMA dermatology. p. E1-E13

Research output: Contribution to journalArticle

Open Access
Skin Abnormalities
Atopic Dermatitis
Skin
Biomarkers
Biopsy