• 23008 Citations
1974 …2022
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Research Output 1974 2020

2020

Monocytes prime autoreactive T cells after myocardial infarction

DeBerge, M., Yu, S., Dehn, S., Ifergan, I., Yeap, X. Y., Filipp, M., Becker, A., Luo, X., Miller, S. & Thorp, E. B., Jan 1 2020, In : American Journal of Physiology - Heart and Circulatory Physiology. 318, 1, p. H116-H123

Research output: Contribution to journalArticle

Monocytes
Myocardial Infarction
T-Lymphocytes
Autoantigens
Lymph Nodes
2019
6 Citations (Scopus)

Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation

Saito, E., Kuo, R., Pearson, R. M., Gohel, N., Cheung, B., King, N. J. C., Miller, S. D. & Shea, L. D., Apr 28 2019, In : Journal of Controlled Release. 300, p. 185-196 12 p.

Research output: Contribution to journalArticle

Nanoparticles
Monocytes
Neutrophils
Autoimmune Experimental Encephalomyelitis
Inflammation

Design of biodegradable nanoparticles to modulate phenotypes of antigen-presenting cells for antigen-specific treatment of autoimmune disease

Saito, E., Kuo, R., Kramer, K. R., Gohel, N., Giles, D. A., Moore, B. B., Miller, S. D. & Shea, L. D., Nov 2019, In : Biomaterials. 222, 119432.

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Antigens
Nanoparticles
Autoimmune Diseases
Phenotype
16 Citations (Scopus)

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza, A., Chang, H. D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W. W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L. N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C. T., Bari, S., Barnaba, V. & 416 others, Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Blanco, A., Boardman, D. A., Bogdan, C., Borger, J. G., Borsellino, G., Boulais, P. E., Bradford, J. A., Brenner, D., Brinkman, R. R., Brooks, A. E. S., Busch, D. H., Büscher, M., Bushnell, T. P., Calzetti, F., Cameron, G., Cammarata, I., Cao, X., Cardell, S. L., Casola, S., Cassatella, M. A., Cavani, A., Celada, A., Chatenoud, L., Chattopadhyay, P. K., Chow, S., Christakou, E., Čičin-Šain, L., Clerici, M., Colombo, F. S., Cook, L., Cooke, A., Cooper, A. M., Corbett, A. J., Cosma, A., Cosmi, L., Coulie, P. G., Cumano, A., Cvetkovic, L., Dang, V. D., Dang-Heine, C., Davey, M. S., Davies, D., De Biasi, S., Del Zotto, G., Dela Cruz, G. V., Delacher, M., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Di Santo, J. P., Diefenbach, A., Dieli, F., Dolf, A., Dörner, T., Dress, R. J., Dudziak, D., Dustin, M., Dutertre, C. A., Ebner, F., Eckle, S. B. G., Edinger, M., Eede, P., Ehrhardt, G. R. A., Eich, M., Engel, P., Engelhardt, B., Erdei, A., Esser, C., Everts, B., Evrard, M., Falk, C. S., Fehniger, T. A., Felipo-Benavent, M., Ferry, H., Feuerer, M., Filby, A., Filkor, K., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G. A., Frehse, B., Frenette, P. S., Frischbutter, S., Fritzsche, W., Galbraith, D. W., Gangaev, A., Garbi, N., Gaudilliere, B., Gazzinelli, R. T., Geginat, J., Gerner, W., Gherardin, N. A., Ghoreschi, K., Gibellini, L., Ginhoux, F., Goda, K., Godfrey, D. I., Goettlinger, C., González-Navajas, J. M., Goodyear, C. S., Gori, A., Grogan, J. L., Grummitt, D., Grützkau, A., Haftmann, C., Hahn, J., Hammad, H., Hämmerling, G., Hansmann, L., Hansson, G., Harpur, C. M., Hartmann, S., Hauser, A., Hauser, A. E., Haviland, D. L., Hedley, D., Hernández, D. C., Herrera, G., Herrmann, M., Hess, C., Höfer, T., Hoffmann, P., Hogquist, K., Holland, T., Höllt, T., Holmdahl, R., Hombrink, P., Houston, J. P., Hoyer, B. F., Huang, B., Huang, F. P., Huber, J. E., Huehn, J., Hundemer, M., Hunter, C. A., Hwang, W. Y. K., Iannone, A., Ingelfinger, F., Ivison, S. M., Jäck, H. M., Jani, P. K., Jávega, B., Jonjic, S., Kaiser, T., Kalina, T., Kamradt, T., Kaufmann, S. H. E., Keller, B., Ketelaars, S. L. C., Khalilnezhad, A., Khan, S., Kisielow, J., Klenerman, P., Knopf, J., Koay, H. F., Kobow, K., Kolls, J. K., Kong, W. T., Kopf, M., Korn, T., Kriegsmann, K., Kristyanto, H., Kroneis, T., Krueger, A., Kühne, J., Kukat, C., Kunkel, D., Kunze-Schumacher, H., Kurosaki, T., Kurts, C., Kvistborg, P., Kwok, I., Landry, J., Lantz, O., Lanuti, P., LaRosa, F., Lehuen, A., LeibundGut-Landmann, S., Leipold, M. D., Leung, L. Y. T., Levings, M. K., Lino, A. C., Liotta, F., Litwin, V., Liu, Y., Ljunggren, H. G., Lohoff, M., Lombardi, G., Lopez, L., López-Botet, M., Lovett-Racke, A. E., Lubberts, E., Luche, H., Ludewig, B., Lugli, E., Lunemann, S., Maecker, H. T., Maggi, L., Maguire, O., Mair, F., Mair, K. H., Mantovani, A., Manz, R. A., Marshall, A. J., Martínez-Romero, A., Martrus, G., Marventano, I., Maslinski, W., Matarese, G., Mattioli, A. V., Maueröder, C., Mazzoni, A., McCluskey, J., McGrath, M., McGuire, H. M., McInnes, I. B., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Miller, S. D., Mills, K. H. G., Minderman, H., Mjösberg, J., Moore, J., Moran, B., Moretta, L., Mosmann, T. R., Müller, S., Multhoff, G., Muñoz, L. E., Münz, C., Nakayama, T., Nasi, M., Neumann, K., Ng, L. G., Niedobitek, A., Nourshargh, S., Núñez, G., O'Connor, J. E., Ochel, A., Oja, A., Ordonez, D., Orfao, A., Orlowski-Oliver, E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Pattanapanyasat, K., Paulsen, M., Pavlinic, D., Penter, L., Peterson, P., Peth, C., Petriz, J., Piancone, F., Pickl, W. F., Piconese, S., Pinti, M., Pockley, A. G., Podolska, M. J., Poon, Z., Pracht, K., Prinz, I., Pucillo, C. E. M., Quataert, S. A., Quatrini, L., Quinn, K. M., Radbruch, H., Radstake, T. R. D. J., Rahmig, S., Rahn, H. P., Rajwa, B., Ravichandran, G., Raz, Y., Rebhahn, J. A., Recktenwald, D., Reimer, D., Reis e Sousa, C., Remmerswaal, E. B. M., Richter, L., Rico, L. G., Riddell, A., Rieger, A. M., Robinson, J. P., Romagnani, C., Rubartelli, A., Ruland, J., Saalmüller, A., Saeys, Y., Saito, T., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sandrock, I., Santoni, A., Sanz, R. B., Saresella, M., Sautes-Fridman, C., Sawitzki, B., Schadt, L., Scheffold, A., Scherer, H. U., Schiemann, M., Schildberg, F. A., Schimisky, E., Schlitzer, A., Schlosser, J., Schmid, S., Schmitt, S., Schober, K., Schraivogel, D., Schuh, W., Schüler, T., Schulte, R., Schulz, A. R., Schulz, S. R., Scottá, C., Scott-Algara, D., Sester, D. P., Shankey, T. V., Silva-Santos, B., Simon, A. K., Sitnik, K. M., Sozzani, S., Speiser, D. E., Spidlen, J., Stahlberg, A., Stall, A. M., Stanley, N., Stark, R., Stehle, C., Steinmetz, T., Stockinger, H., Takahama, Y., Takeda, K., Tan, L., Tárnok, A., Tiegs, G., Toldi, G., Tornack, J., Traggiai, E., Trebak, M., Tree, T. I. M., Trotter, J., Trowsdale, J., Tsoumakidou, M., Ulrich, H., Urbanczyk, S., van de Veen, W., van den Broek, M., van der Pol, E., Van Gassen, S., Van Isterdael, G., van Lier, R. A. W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H. D., von Borstel, A., von Volkmann, K., Waisman, A., Walker, R. V., Wallace, P. K., Wang, S. A., Wang, X. M., Ward, M. D., Ward-Hartstonge, K. A., Warnatz, K., Warnes, G., Warth, S., Waskow, C., Watson, J. V., Watzl, C., Wegener, L., Weisenburger, T., Wiedemann, A., Wienands, J., Wilharm, A., Wilkinson, R. J., Willimsky, G., Wing, J. B., Winkelmann, R., Winkler, T. H., Wirz, O. F., Wong, A., Wurst, P., Yang, J. H. M., Yang, J., Yazdanbakhsh, M., Yu, L., Yue, A., Zhang, H., Zhao, Y., Ziegler, S. M., Zielinski, C., Zimmermann, J. & Zychlinsky, A., Oct 1 2019, In : European Journal of Immunology. 49, 10, p. 1457-1973 517 p.

Research output: Contribution to journalArticle

Open Access
Flow Cytometry
Guidelines
Allergy and Immunology
Phenotype
Research

Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

Singh, A., Ramachandran, S., Graham, M. L., Daneshmandi, S., Heller, D., Suarez-Pinzon, W. L., Balamurugan, A. N., Ansite, J. D., Wilhelm, J. J., Yang, A., Zhang, Y., Palani, N. P., Abrahante, J. E., Burlak, C., Miller, S. D., Luo, X. & Hering, B. J., Dec 1 2019, In : Nature communications. 10, 1, 3495.

Research output: Contribution to journalArticle

Open Access
primates
Transplantation Tolerance
leukocytes
Primates
Allografts
1 Citation (Scopus)

Nanoparticles containing an insulin-ChGA hybrid peptide protect from transfer of autoimmune diabetes by shifting the balance between effector T cells and regulatory T cells

Jamison, B. L., Neef, T., Goodspeed, A., Bradley, B., Baker, R. L., Miller, S. D. & Haskins, K., Jan 1 2019, In : Journal of Immunology. 203, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Type 1 Diabetes Mellitus
Nanoparticles
Insulin
T-Lymphocytes
3 Citations (Scopus)

Overcoming challenges in treating autoimmuntity: Development of tolerogenic immune-modifying nanoparticles

Pearson, R. M., Podojil, J. R., Shea, L. D., King, N. J. C., Miller, S. D. & Getts, D. R., Jun 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 18, p. 282-291 10 p.

Research output: Contribution to journalReview article

Nanoparticles
Celiac Disease
T-Lymphocytes
Autoimmune Diseases
Clinical Trials
4 Citations (Scopus)

Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis

Chen, Y., Podojil, J. R., Kunjamma, R. B., Jones, J., Weiner, M., Lin, W., Miller, S. D. & Popko, B., Feb 1 2019, In : Brain. 142, 2, p. 344-361 18 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Oligodendroglia
Therapeutics
Autoimmune Experimental Encephalomyelitis
CNS Demyelinating Autoimmune Diseases
2018
18 Citations (Scopus)

APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

Glaser, A. P., Fantini, D., Wang, Y., Yu, Y., Rimar, K. J., Podojil, J. R., Miller, S. D. & Meeks, J. J., Jan 1 2018, In : Oncotarget. 9, 4, p. 4537-4548 12 p.

Research output: Contribution to journalArticle

Mutagenesis
DNA Damage
Carcinoma
Mutation
Survival
9 Citations (Scopus)

B7-H4 modulates regulatory CD4+T cell induction and function via ligation of a semaphorin 3a/Plexin A4/Neuropilin-1 Complex

Podojil, J. R., Chiang, M. Y., Ifergan, I., Copeland, R., Liu, L. N., Maloveste, S., Langermann, S., Liebenson, D., Balabanov, R. D., Chi, H., Chen, L., Vignali, D. A. A. & Miller, S. D., Aug 1 2018, In : Journal of Immunology. 201, 3, p. 897-907 11 p.

Research output: Contribution to journalArticle

Semaphorin-3A
Neuropilin-1
Regulatory T-Lymphocytes
Ligation
Semaphorins
11 Citations (Scopus)

Conjugation of Transforming Growth Factor Beta to Antigen-Loaded Poly(lactide- co -glycolide) Nanoparticles Enhances Efficiency of Antigen-Specific Tolerance

Casey, L. M., Pearson, R. M., Hughes, K. R., Liu, J. M. H., Rose, J. A., North, M. G., Wang, L. Z., Lei, M., Miller, S. D. & Shea, L. D., Mar 21 2018, In : Bioconjugate Chemistry. 29, 3, p. 813-823 11 p.

Research output: Contribution to journalArticle

Polyglactin 910
Antigens
Transforming Growth Factor beta
Nanoparticles
Autoimmunity
5 Citations (Scopus)

ILDR2-Fc is a novel regulator of immune homeostasis and inducer of antigen-specific immune tolerance

Podojil, J. R., Hecht, I., Chiang, M. Y., Vaknin, I., Barbiro, I., Novik, A., Neria, E., Rotman, G. & Miller, S. D., Mar 15 2018, In : Journal of Immunology. 200, 6, p. 2013-2024 12 p.

Research output: Contribution to journalArticle

Immune Tolerance
Homeostasis
Antigens
Immunomodulation
Autoimmune Experimental Encephalomyelitis
5 Citations (Scopus)

ILDR2 is a novel B7-like protein that negatively regulates T cell responses

Hecht, I., Toporik, A., Podojil, J. R., Vaknin, I., Cojocaru, G., Oren, A., Aizman, E., Liang, S. C., Leung, L., Dicken, Y., Novik, A., Marbach-Bar, N., Elmesmari, A., Tange, C., Gilmour, A., McIntyre, D., Kurowska-Stolarska, M., McNamee, K., Leitner, J., Greenwald, S. & 8 others, Dassa, L., Levine, Z., Steinberger, P., Williams, R. O., Miller, S. D., McInnes, I. B., Neria, E. & Rotman, G., Mar 15 2018, In : Journal of Immunology. 200, 6, p. 2025-2037 13 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Proteins
Cytokines
Immunoglobulin Fc Fragments
Experimental Arthritis
9 Citations (Scopus)

Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy

Xu, D., Robinson, A. P., Ishii, T., Duncan, DA. S., Alden, T. D., Goings, G. E., Ifergan, I., Podojil, J. R., Penaloza-MacMaster, P., Kearney, J. A., Swanson, G. T., Miller, S. D. & Koh, S., Apr 1 2018, In : Journal of Experimental Medicine. 215, 4, p. 1169-1186 18 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Interleukin-17
Granulocyte-Macrophage Colony-Stimulating Factor
Pediatrics
T-Lymphocytes

The use of biodegradable nanoparticles for tolerogenic therapy of allergic inflammation

Smarr, C. B. & Miller, S. D., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 353-358 6 p. (Methods in Molecular Biology; vol. 1799).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nanoparticles
Inflammation
Antigens
Polyglactin 910
Therapeutics
10 Citations (Scopus)

Tolerogenic Ag-PLG nanoparticles induce tregs to suppress activated diabetogenic CD4 and CD8 T cells

Prasad, S., Neef, T., Xu, D., Podojil, J. R., Getts, D. R., Shea, L. D. & Miller, S. D., May 1 2018, In : Journal of Autoimmunity. 89, p. 112-124 13 p.

Research output: Contribution to journalArticle

Nanoparticles
T-Lymphocytes
Type 1 Diabetes Mellitus
Antigens
Polyglactin 910
2017
28 Citations (Scopus)

An antigen-encapsulating nanoparticle platform for TH1/17 immune tolerance therapy

McCarthy, D. P., Yap, J. W. T., Harp, C. T., Song, W. K., Chen, J., Pearson, R. M., Miller, S. D. & Shea, L. D., Jan 1 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 1, p. 191-200 10 p.

Research output: Contribution to journalArticle

Immune Tolerance
Antigens
Nanoparticles
Therapeutics
Immunosuppressive Agents
19 Citations (Scopus)

Controlled Delivery of Single or Multiple Antigens in Tolerogenic Nanoparticles Using Peptide-Polymer Bioconjugates

Pearson, R. M., Casey, L. M., Hughes, K. R., Wang, L. Z., North, M. G., Getts, D. R., Miller, S. D. & Shea, L. D., Jul 5 2017, In : Molecular Therapy. 25, 7, p. 1655-1664 10 p.

Research output: Contribution to journalArticle

Nanoparticles
Polymers
Antigens
Peptides
Polyglactin 910
7 Citations (Scopus)

Differential Role of B Cells and IL-17 Versus IFN-γ during Early and Late Rejection of Pig Islet Xenografts in Mice

Kang, H. K., Wang, S., Dangi, A., Zhang, X., Singh, A., Zhang, L., Rosati, J. M., Suarez-Pinzon, W., Deng, X., Chen, X., Thorp, E. B., Hering, B. J., Miller, S. D. & Luo, X., Aug 1 2017, In : Transplantation. 101, 8, p. 1801-1810 10 p.

Research output: Contribution to journalArticle

Interleukin-17
Heterografts
B-Lymphocytes
Swine
Ethyldimethylaminopropyl Carbodiimide
15 Citations (Scopus)

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

Wang, C., Zhang, C. J., Martin, B. N., Bulek, K., Kang, Z., Zhao, J., Bian, G., Carman, J. A., Gao, J., Dongre, A., Xue, H., Miller, S. D., Qian, Y., Hambardzumyan, D., Hamilton, T., Ransohoff, R. M. & Li, X., May 31 2017, In : Nature communications. 8, 15508.

Research output: Contribution to journalArticle

Interleukin-17
gene expression
Oligodendroglia
Cell proliferation
Gene expression
14 Citations (Scopus)

Intravenous immune-modifying nanoparticles as a therapy for spinal cord injury in mice

Jeong, S. J., Cooper, J. G., Ifergan, I., McGuire, T. L., Xu, D., Hunter, Z., Sharma, S., McCarthy, D., Miller, S. D. & Kessler, J. A., Dec 2017, In : Neurobiology of Disease. 108, p. 73-82 10 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Nanoparticles
Monocytes
Microglia
Cicatrix
28 Citations (Scopus)

In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance

Pearson, R. M., Casey, L. M., Hughes, K. R., Miller, S. D. & Shea, L. D., May 15 2017, In : Advanced Drug Delivery Reviews. 114, p. 240-255 16 p.

Research output: Contribution to journalReview article

Technology
Antigens
Peripheral Tolerance
Immune Tolerance
Allografts
8 Citations (Scopus)

Murine corneal inflammation and nerve damage after infection with HSV-1 are promoted by HVEM and ameliorated by immune-modifying nanoparticle therapy

Edwards, R. G., Kopp, S. J., Ifergan, I., Shui, J. W., Kronenberg, M., Miller, S. D. & Longnecker, R., Jan 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 1, p. 282-291 10 p.

Research output: Contribution to journalArticle

Virus Internalization
Human Herpesvirus 1
Nanoparticles
Inflammation
Cornea
3 Citations (Scopus)

Pak2 is essential for the function of Foxp3+ regulatory T cells through maintaining a suppressive Treg phenotype

O'Hagan, K. L., Miller, S. D. & Phee, H., Dec 1 2017, In : Scientific reports. 7, 1, 17097.

Research output: Contribution to journalArticle

p21-Activated Kinases
Regulatory T-Lymphocytes
Phenotype
Transcription Factors
Cytokines
21 Citations (Scopus)

Peptide-Conjugated Nanoparticles Reduce Positive Co-stimulatory Expression and T Cell Activity to Induce Tolerance

Kuo, R., Saito, E., Miller, S. D. & Shea, L. D., Jul 5 2017, In : Molecular Therapy. 25, 7, p. 1676-1685 10 p.

Research output: Contribution to journalArticle

Nanoparticles
T-Lymphocytes
Peptides
Antigens
Antigen-Presenting Cells
23 Citations (Scopus)

Potential targeting of B7-H4 for the treatment of cancer

Podojil, J. R. & Miller, S. D., Mar 1 2017, In : Immunological Reviews. 276, 1, p. 40-51 12 p.

Research output: Contribution to journalReview article

Neoplasms
Tumor Microenvironment
Macrophages
Regulatory T-Lymphocytes
Immunity
60 Citations (Scopus)

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

Plebanek, M. P., Angeloni, N. L., Vinokour, E., Li, J., Henkin, A., Martinez-Marin, D., Filleur, S., Bhowmick, R., Henkin, J., Miller, S. D., Ifergan, I., Lee, Y., Osman, I., Thaxton, C. S. & Volpert, O. V., Dec 1 2017, In : Nature communications. 8, 1, 1319.

Research output: Contribution to journalArticle

monocytes
Exosomes
metastasis
surveillance
Monocytes
20 Citations (Scopus)

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity

Ifergan, I., Davidson, T. S., Kebir, H., Xu, D., Palacios-Macapagal, D., Cann, J., Rodgers, J. M., Hunter, Z. N., Pittet, C. L., Beddow, S., Jones, C. A., Prat, A., Sleeman, M. A. & Miller, S. D., Nov 2017, In : Journal of Autoimmunity. 84, p. 1-11 11 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor Receptors
Granulocyte-Macrophage Colony-Stimulating Factor
Autoimmunity
Chronic Progressive Multiple Sclerosis
Autoimmune Experimental Encephalomyelitis
5 Citations (Scopus)

Tolerogenic Nanoparticles to Treat Islet Autoimmunity

Neef, T. & Miller, S. D., Oct 1 2017, In : Current diabetes reports. 17, 10, 84.

Research output: Contribution to journalReview article

Autoimmunity
Type 1 Diabetes Mellitus
Nanoparticles
Nanomedicine
Nanotechnology
2016
33 Citations (Scopus)

Biodegradable antigen-associated PLG nanoparticles tolerize Th2-mediated allergic airway inflammation pre- and postsensitization

Smarr, C. B., Yap, W. T., Neef, T. P., Pearson, R. M., Hunter, Z. N., Ifergan, I., Getts, D. R., Bryce, P. J., Shea, L. D. & Miller, S. D., May 3 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 18, p. 5059-5064 6 p.

Research output: Contribution to journalArticle

Nanoparticles
Inflammation
Antigens
Immunotherapy
Hypersensitivity
12 Citations (Scopus)

Cutting edge: CD99 is a novel therapeutic target for control of T cell-mediated central nervous system autoimmune disease

Winger, R. C., Harp, C. T., Chiang, M. Y., Sullivan, D. P., Watson, R. L., Weber, E. W., Podoji, J. R., Miller, S. D. & Muller, W. A., Feb 15 2016, In : Journal of Immunology. 196, 4, p. 1443-1448 6 p.

Research output: Contribution to journalArticle

Autoimmune Diseases of the Nervous System
Central Nervous System Diseases
Leukocytes
Autoimmune Experimental Encephalomyelitis
T-Lymphocytes
21 Citations (Scopus)
Autoimmune Experimental Encephalomyelitis
Myeloid Cells
MicroRNAs
Dendritic Cells
Multiple Sclerosis
3 Citations (Scopus)

Erratum: Harnessing Nanoparticles for Immune Modulation (Trends in Immunology (2015) 36(7) (419–427) (S147149061500126X) (10.1016/j.it.2015.05.007))

Getts, D. R., Shea, L. D., Miller, S. D. & King, N. J. C., Oct 1 2016, In : Trends in Immunology. 37, 10, 1 p.

Research output: Contribution to journalComment/debate

Japanese Encephalitis
Allergy and Immunology
Nanoparticles
6 Citations (Scopus)

HIF-2α in resting macrophages tempers mitochondrial reactive oxygen species to selectively repress MARCO-dependent phagocytosis

Dehn, S., De Berge, M., Yeap, X. Y., Yvan-Charvet, L., Fang, D., Eltzschig, H. K., Miller, S. D. & Thorp, E. B., Nov 1 2016, In : Journal of Immunology. 197, 9, p. 3639-3649 11 p.

Research output: Contribution to journalArticle

Phagocytosis
Reactive Oxygen Species
Macrophages
Interleukin-4
Antioxidants
28 Citations (Scopus)

Immune Tolerance for Autoimmune Disease and Cell Transplantation

Luo, X., Miller, S. D. & Shea, L. D., Jul 11 2016, In : Annual Review of Biomedical Engineering. 18, p. 181-205 25 p.

Research output: Contribution to journalArticle

Immune Tolerance
Cell Transplantation
Antigens
Autoimmune Diseases
Immune system
13 Citations (Scopus)

Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis

James, R. E., Hillis, J., Adorján, I., Gration, B., Mundim, M. V., Iqbal, A. J., Majumdar, M. M., Yates, R. L., Richards, M. M. H., Goings, G. E., Deluca, G. C., Greaves, D. R., Miller, S. D. & Szele, F. G., Jan 1 2016, In : Glia. 64, 1, p. 105-121 17 p.

Research output: Contribution to journalArticle

Galectin 3
Lateral Ventricles
Multiple Sclerosis
Theilovirus
Cell Count
22 Citations (Scopus)

Pattern of CXCR7 Gene Expression in Mouse Brain Under Normal and Inflammatory Conditions

Banisadr, G., Podojil, J. R., Miller, S. D. & Miller, R. J., Mar 1 2016, In : Journal of Neuroimmune Pharmacology. 11, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

Chemokine CXCL12
Gene Expression
Lateral Ventricles
Brain
Oligodendroglia
19 Citations (Scopus)

Tolerance induction using nanoparticles bearing HY peptides in bone marrow transplantation

Hlavaty, K. A., McCarthy, D. P., Saito, E., Yap, W. T., Miller, S. D. & Shea, L. D., Jan 1 2016, In : Biomaterials. 76, p. 1-10 10 p.

Research output: Contribution to journalArticle

Bearings (structural)
Antigens
Bone Marrow Transplantation
Transplants
Nanoparticles
2015
17 Citations (Scopus)

Cellular and molecular targeting for nanotherapeutics in transplantation tolerance

Hlavaty, K. A., Luo, X., Shea, L. D. & Miller, S. D., Sep 1 2015, In : Clinical Immunology. 160, 1, p. 14-23 10 p.

Research output: Contribution to journalReview article

Transplantation Tolerance
Technology
Transplants
Cell Engineering
Antigens
5 Citations (Scopus)

Deficient natural killer dendritic cell responses underlay the induction of theiler’s virus-induced autoimmunity

Chastain, E. M. L., Getts, D. R. & Miller, S. D., Jul 21 2015, In : mBio. 6, 4, e01175-15.

Research output: Contribution to journalArticle

Theilovirus
Autoimmunity
Natural Killer Cells
Dendritic Cells
Demyelinating Diseases
167 Citations (Scopus)

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

Najm, F. J., Madhavan, M., Zaremba, A., Shick, E., Karl, R. T., Factor, D. C., Miller, T. E., Nevin, Z. S., Kantor, C., Sargent, A., Quick, K. L., Schlatzer, D. M., Tang, H., Papoian, R., Brimacombe, K. R., Shen, M., Boxer, M. B., Jadhav, A., Robinson, A. P., Podojil, J. R. & 3 others, Miller, S. D., Miller, R. H. & Tesar, P. J., Jun 11 2015, In : Nature. 522, 7555, p. 216-220 5 p.

Research output: Contribution to journalArticle

Oligodendroglia
Stem Cells
Clobetasol
Miconazole
Pharmaceutical Preparations
24 Citations (Scopus)

ER chaperone BiP/GRP78 is required for myelinating cell survival and provides protection during experimental autoimmune encephalomyelitis

Hussien, Y., Podojil, J. R., Robinson, A. P., Lee, A. S., Miller, S. D. & Popko, B., Dec 2 2015, In : Journal of Neuroscience. 35, 48, p. 15921-15933 13 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Oligodendroglia
Endoplasmic Reticulum
Cell Survival
Carrier Proteins
21 Citations (Scopus)

Experimental autoimmune encephalomyelitis in mice

Terry, R. L., Ifergan, I. & Miller, S. D., Jan 1 2015, In : Methods in Molecular Biology. 1304, p. 145-160 16 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Myelin-Oligodendrocyte Glycoprotein
Proteolipids
Peptides
76 Citations (Scopus)

Harnessing nanoparticles for immune modulation

Getts, D. R., Shea, L. D., Miller, S. D. & King, N. J. C., Jul 1 2015, In : Trends in Immunology. 36, 7, p. 419-427 9 p.

Research output: Contribution to journalReview article

Nanoparticles
Peripheral Tolerance
Inflammation
Immune Tolerance
Mononuclear Phagocyte System
13 Citations (Scopus)

IL-17A activates ERK1/2 and enhances differentiation of oligodendrocyte progenitor cells

Rodgers, J. M., Robinson, A. P., Rosler, E. S., Lariosa-Willingham, K., Persons, R. E., Dugas, J. C. & Miller, S. D., May 1 2015, In : Glia. 63, 5, p. 768-779 12 p.

Research output: Contribution to journalArticle

Interleukin-17
Oligodendroglia
Stem Cells
Myelin Proteolipid Protein
Chemokines
11 Citations (Scopus)

Interleukin-7 is required for CD4+ T cell activation and autoimmune neuroinflammation

Lawson, B. R., Gonzalez-Quintial, R., Eleftheriadis, T., Farrar, M. A., Miller, S. D., Sauer, K., McGavern, D. B., Kono, D. H., Baccala, R. & Theofilopoulos, A. N., Dec 1 2015, In : Clinical Immunology. 161, 2, p. 260-269 10 p.

Research output: Contribution to journalArticle

Interleukin-7
T-Lymphocytes
Autoimmune Experimental Encephalomyelitis
Autoantigens
Homeostasis
68 Citations (Scopus)

Oligodendrocyte death results in immune-mediated CNS demyelination

Traka, M., Podojil, J. R., Mccarthy, D. P., Miller, S. D. & Popko, B., Dec 29 2015, In : Nature Neuroscience. 19, 1, p. 65-74 10 p.

Research output: Contribution to journalArticle

Oligodendroglia
Demyelinating Diseases
Myelin Sheath
Autoimmunity
Myelin-Oligodendrocyte Glycoprotein
51 Citations (Scopus)

Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic

Way, S. W., Podojil, J. R., Clayton, B. L., Zaremba, A., Collins, T. L., Kunjamma, R. B., Robinson, A., Brugarolas, P., Miller, R. H., Miller, S. D. & Popko, B., Jan 1 2015, In : Nature communications. 6, 6532.

Research output: Contribution to journalArticle

Guanabenz
interferon
pathogenesis
Oligodendroglia
Multiple Sclerosis
14 Citations (Scopus)

Preemptive Tolerogenic Delivery of Donor Antigens for Permanent Allogeneic Islet Graft Protection

Wang, S., Zhang, X., Zhang, L., Bryant, J., Kheradmand, T., Hering, B. J., Miller, S. D. & Luo, X., Jan 1 2015, In : Cell transplantation. 24, 6, p. 1155-1165 11 p.

Research output: Contribution to journalArticle

Islets of Langerhans Transplantation
Cell Transplantation
Antigens
Islets of Langerhans
Grafts
16 Citations (Scopus)

Tempering allorecognition to induce transplant tolerance with chemically modified apoptotic donor cells

McCarthy, D. P., Bryant, J., Galvin, J. P., Miller, S. D. & Luo, X., Jun 1 2015, In : American Journal of Transplantation. 15, 6, p. 1475-1483 9 p.

Research output: Contribution to journalReview article

Ethyldimethylaminopropyl Carbodiimide
Transplants
Immune Tolerance
Antigens
Leukocytes