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Stuart Rich

  • 25612 Citations
1979 …2020

Research output per year

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Personal profile

Research Interests

Dr. Rich has a career interest in understanding the causes and treatments of pulmonary hypertension. He was principle investigator for the NIH Registry on Primary Pulmonary Hypertension, the first of its kind, and has been the leader of the largest clinical center in the USA for evaluating and treating patients with pulmonary hypertension since 1980. Dr. Rich has conducted pioneering research on the molecular mechanisms, epidemiology, clinical presentation, natural history and treatments of the disease. This knowledge has lead to the discovery of more effective treatments for pulmonary hypertension, including the use of medicines like anticoagulants, calcium channel blockers, and prostacyclins. His pioneering research has led to a greater understanding of all types of pulmonary hypertension.

Dr. Rich is currently involved with novel drug and device development to treat advanced pulmonary hypertension and right heart failure. This includes disease modifying drugs for pulmonary arterial hypertension, a first-in-man for pulmonary hypertension associated with heart failure with preserved function, and a durable right ventricular assist device. In addition, he is a collaborator with the World Health Organization Global Burden of Disease initiative and the newly initiated pulmonary hypertension project.

He has expanded the Pulmonary Vascular Disease Program at Northwestern to now offer every approved intervention for patients, including every approved medicine, interventional procedures, surgical pulmonary endarterectomy, and lung transplantation. He also has created an alliance with the Pulmonary Hypertension Program at Lurie Children's Hospital to now offer clinical services to any patient with pulmonary hypertension of any age.

Training Experience

1976Internship, Washington University in St Louis, Barnes Jewish Hospital
1978Residency, Washington University in St Louis, Barnes Jewish Hospital
1980Fellowship, University of Chicago Hospitals

Education/Academic qualification

MD, Loyola University/Stritch School of Medicine

… → 1974

Research interests

  • Adult Congenital Heart Disease
  • Cardiovascular Diseases
  • Clinical Research
  • Clinical Trial Methodology
  • Critical Cardiac Care
  • Drug Discovery
  • Heart Failure
  • Pulmonary Hypertension

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Grants

Prot#LTI-302: A Global, Open-Label, Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Inhaled LIQ861(Treprostinil) in Pulmonary Arterial Hypertension (WHO Group 1) Patients

Rich, S.

Nuventra, Inc., Liquidia Technologies, Inc.

4/29/19 → 4/29/22

Project: Research project

Prot#LTI-301: A Phase 3 Open-label, Multicenter Study to Evaluate the Long-term Safety and Tolerability of Inhaled LIQ861 (Treprostinil) in Pulmonary Arterial Hypertension (WHO Group 1) Patients

Rich, S.

Nuventra, Inc., Liquidia Technologies, Inc.

1/24/18 → 1/24/21

Project: Research project

Prot #CLPR-010: SCOUT Study - Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) for Symptomatic Chronic Functional Tricuspid Regurgitation (CLPR-010)

Rich, S.

Mitralign Inc.

10/8/15 → 10/8/21

Project: Research project

Prot# PULSE-PAH-004: A Phase 3, Placebo Controlled, Double-blind, Randomized, Clinical Study to Determine Efficacy, Safety and Tolerability of Pulsed, Inhaled Nitric Oxide (iNO) versus Placebo in Symptomatic Subjects with Pulmonary Arterial Hypertension (

Rich, S.

Worldwide Clinical Trials, Inc., Bellerophon Pulse Technologies LLC

11/2/16 → 11/2/19

Project: Research project

Research Output

Dual-Energy Computed Tomography as an Alternative Noninvasive Study for Evaluation of Chronic Thromboembolic Pulmonary Hypertension Postoperatively

Desai, A., Malaisrie, S. C., Cuttica, M. J., Freed, B. H., Rich, S., Schimmel, D. & Avery, R., May 1 2020, In : Circulation: Cardiovascular Imaging. e010168.

Research output: Contribution to journal › Comment/debate

Novel shunt modification with an adjustable stent-embedded “fenestrated” septal occluder in a patient with pulmonary hypertension

Yadlapati, A., Wax, D. F., Rich, S. & Ricciardi, M. J., Jun 1 2019, In : Catheterization and Cardiovascular Interventions. 93, 7, p. 1382-1384 3 p.

Research output: Contribution to journal › Article

    • The use of a durable right ventricular assist device for isolated right ventricular failure due to combined pre- and postcapillary pulmonary hypertension

    Vullaganti, S., Tibrewala, A., Rich, J. D., Pham, D. T. & Rich, S., Apr 1 2019, In : Pulmonary Circulation. 9, 2

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Are anticoagulants still indicated in pulmonary arterial hypertension?

    Olschewski, H. & Rich, S., Oct 1 2018, In : Pulmonary Circulation. 8, 4

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Pulmonary hypertension: the unaddressed global health burden

    Rich, S., Haworth, S. G., Hassoun, P. M. & Yacoub, M. H., Aug 2018, In : The Lancet Respiratory Medicine. 6, 8, p. 577-579 3 p.

    Research output: Contribution to journal › Comment/debate

    4 Scopus citations