Grants per year
Personal profile
Research Interests
Growing up in India, I had a humble beginning, where my family showed me the way of simple living and high thinking. I did my undergrad in Zoology and graduated as a salutatorian with National Scholarship for excellence. I completed my Master's degree from University of Calcutta, a top ranking University that produced three Nobel laureates. After awarded with a rare Overseas Travel award, I pursued my PhD in the prestigious Howard University with full scholarship. I graduated as an Exemplar Graduate Student with 4 esteemed peer-reviewed publications and joined a stellar group of Brain Cancer Researchers at Emory University Medical School (Ranked#22). After completing my postdoctoral studies with two highly esteemed articles and a book chapter, I joined the star-studded Northwestern University, Feinberg School of Medicine (Ranked# 11). In my journey till date, I have achieved numerous awards and recognition. Beside academic achievements, my work on brain cancer was recognized by local, national and international conferences. I served as a judge in the The Allied Genetics Conference in 2015 and am a young-investigator committee member in Society for Neuro-Oncology Conference. I was featured in the Delta Sky Magazine advertising the excellence of Emory in research. I also represented Emory in Atlanta Journal Constitution and at the NCI website when The Winship Cancer Institute received the Comprehensive Cancer Center Designation from NIH. I am thrilled to be a part of Northwestern community and currently an associate member of Lurie Cancer Center. With my work, I am dedicated to contribute significantly in the research and therapy development against cancer.
My primary interest is to understand the self-renewing properties of glioma stem cells (GSCs), the driving force behind glioblastoma (GBM) growth, recurrence and therapeutic resistance. My ultimate goal of finding druggable targets to attenuate their growth. My background in genetics and cell biology, and my past and current experience in neuro-oncology and glioma biology have positioned me to address these biologically and clinically relevant problems. My larger goals in biomedical research are to develop and use models of GBM, including Drosophila and mouse, to uncover mechanisms and to translate the findings to human GBM therapeutics.
Education/Academic qualification
PhD, Howard University
… → 2013
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Network
Grants
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Modeling the Glioblastoma Microenvironment to Uncover Progression Mechanisms and Therapeutic Targets
Brat, D. J., Horbinski, C. M., James, C. D. & Mukherjee, S.
5/1/20 → 4/30/25
Project: Research project
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Molecular Target Variation Across Environments and at Margins of Glioblastoma
11/1/17 → 5/31/19
Project: Research project
Research Output
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Methods for in vitro modeling of glioma invasion: Choosing tools to meet the need
Dundar, B., Markwell, S. M., Sharma, N. V., Olson, C. L., Mukherjee, S. & Brat, D. J., Nov 1 2020, In: Glia. 68, 11, p. 2173-2191 19 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Inhibition of extratumoral chondroitin sulfate glycosaminoglycans stems glioma cell invasion
Logun, M., Simchick, G., Zhao, W., Mao, L., Zhao, Q., Mukherjee, S., Brat, D. & Karumbaiah, L., 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, p. 647 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion
Logun, M. T., Wynens, K. E., Simchick, G., Zhao, W., Mao, L., Zhao, Q., Mukherjee, S., Brat, D. J. & Karumbaiah, L., Nov 1 2019, In: FASEB Journal. 33, 11, p. 11973-11992 20 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells
Mukherjee, S., Tucker-Burden, C., Kaissi, E., Newsam, A., Duggireddy, H., Chau, M., Zhang, C., Diwedi, B., Rupji, M., Seby, S., Kowalski, J., Kong, J., Read, R. & Brat, D. J., May 8 2018, In: Cell Reports. 23, 6, p. 1651-1664 14 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Molecular programs underlying asymmetric stem cell division and their disruption in malignancy
Mukherjee, S. & Brat, D. J., 2017, Results and Problems in Cell Differentiation. Springer-Verlag., Vol. 61. p. 401-421 21 p. (Results and Problems in Cell Differentiation; vol. 61).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations