Subhas Mukherjee

  • 144 Citations
20112019
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research Interests

Growing up in India, I had a humble beginning, where my family showed me the way of simple living and high thinking. I did my undergrad in Zoology and graduated as a salutatorian with National Scholarship for excellence. I completed my Master's degree from University of Calcutta, a top ranking University that produced three Nobel laureates. After awarded with a rare Overseas Travel award, I pursued my PhD in the prestigious Howard University with full scholarship. I graduated as an Exemplar Graduate Student with 4 esteemed peer-reviewed publications and joined a stellar group of Brain Cancer Researchers at Emory University Medical School (Ranked#22). After completing my postdoctoral studies with two highly esteemed articles and a book chapter, I joined the star-studded Northwestern University, Feinberg School of Medicine (Ranked# 11). In my journey till date, I have achieved numerous awards and recognition. Beside academic achievements, my work on brain cancer was recognized by local, national and international conferences. I served as a judge in the The Allied Genetics Conference in 2015 and am a young-investigator committee member in Society for Neuro-Oncology Conference. I was featured in the Delta Sky Magazine advertising the excellence of Emory in research. I also represented Emory in Atlanta Journal Constitution and at the NCI website when The Winship Cancer Institute received the Comprehensive Cancer Center Designation from NIH. I am thrilled to be a part of Northwestern community and currently an associate member of Lurie Cancer Center. With my work, I am dedicated to contribute significantly in the research and therapy development against cancer.

My primary interest is to understand the self-renewing properties of glioma stem cells (GSCs), the driving force behind glioblastoma (GBM) growth, recurrence and therapeutic resistance. My ultimate goal of finding druggable targets to attenuate their growth. My background in genetics and cell biology, and my past and current experience in neuro-oncology and glioma biology have positioned me to address these biologically and clinically relevant problems. My larger goals in biomedical research are to develop and use models of GBM, including Drosophila and mouse, to uncover mechanisms and to translate the findings to human GBM therapeutics.

Education/Academic qualification

PhD, Howard University

… → 2013

Fingerprint Dive into the research topics where Subhas Mukherjee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Stem Cells Medicine & Life Sciences
Drosophila Medicine & Life Sciences
Asymmetric Cell Division Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Glioma Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences
Stem cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2017 2019

Glioblastoma
Glioma
Neoplasms
Residual Neoplasm
Molecular Targeted Therapy

Research Output 2011 2019

  • 144 Citations
  • 9 Article
  • 1 Chapter
  • 1 Conference contribution

Inhibition of extratumoral chondroitin sulfate glycosaminoglycans stems glioma cell invasion

Logun, M., Simchick, G., Zhao, W., Mao, L., Zhao, Q., Mukherjee, S., Brat, D. J. & Karumbaiah, L., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Glioblastoma
Stem cells
Glioma
Tumors
Stem Cells
5 Citations (Scopus)

CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells

Mukherjee, S., Tucker-Burden, C., Kaissi, E., Newsam, A., Duggireddy, H., Chau, M., Zhang, C., Diwedi, B., Rupji, M., Seby, S., Kowalski, J., Kong, J., Read, R. & Brat, D. J., May 8 2018, In : Cell Reports. 23, 6, p. 1651-1664 14 p.

Research output: Contribution to journalArticle

Stem cells
Asymmetric Cell Division
Brain Neoplasms
Glioma
Stem Cells
3 Citations (Scopus)

Molecular programs underlying asymmetric stem cell division and their disruption in malignancy

Mukherjee, S. & Brat, D. J., 2017, Results and Problems in Cell Differentiation. Springer-Verlag., Vol. 61. p. 401-421 21 p. (Results and Problems in Cell Differentiation; vol. 61).

Research output: Chapter in Book/Report/Conference proceedingChapter

Asymmetric Cell Division
Stem Cells
Neoplasms
Biological Phenomena
Cell Division
10 Citations (Scopus)

TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3

Zhang, C., Mukherjee, S., Tucker-Burden, C., Ross, J. L., Chau, M. J., Kong, J. & Brat, D. J., Mar 1 2017, In : Molecular oncology. 11, 3, p. 280-294 15 p.

Research output: Contribution to journalArticle

Amino Acid Motifs
Glioblastoma
Stem Cells
STAT3 Transcription Factor
Ubiquitination
17 Citations (Scopus)

Drosophila brat and human ortholog TRIM3 maintain stem cell equilibrium and suppress brain tumorigenesis by attenuating notch nuclear transport

Mukherjee, S., Tucker-Burden, C., Zhang, C., Moberg, K., Read, R., Hadjipanayis, C. & Brat, D. J., Apr 15 2016, In : Cancer Research. 76, 8, p. 2443-2452 10 p.

Research output: Contribution to journalArticle

Cell Nucleus Active Transport
Brain Neoplasms
Drosophila
Carcinogenesis
Stem Cells