Grants per year
Personal profile
Research Interests
Developmental injuries such as those of either the central or peripheral nervous system have a significant impact on the function of the musculoskeletal system. They affect childhood growth, quality of life, and the ability of these children to actively participate in society. Over the past 15 years I have worked both as a pediatric physical therapist and as a researcher to understand musculoskeletal development and its dysfunction due to injuries to the nervous system at birth. My current research focuses on: A) The role of muscle stem cells in impaired musculoskeletal growth in children with cerebral palsy and B) The contribution of muscle metabolism to increased energy expenditure in children with cerebral palsy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biokinesiology, University of Southern California
… → 2012
MS, Mechanical Engineering, University of Southern California
… → 2010
Physical Therapy, MS, Drexel University
… → 2003
Research interests keywords
- Cell Biology
- Cerebral Palsy
- Movement Control
- Pediatric Physical Therapy
- Stem Cells
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Collaborations and top research areas from the last five years
Grants
- 5 Finished
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Role of Muscle stem cells in sarcomere addition and contracture development
Dayanidhi, S. (PD/PI)
Rehabilitation Institute of Chicago, National Institute of Child Health and Human Development
8/13/18 → 7/31/20
Project: Research project
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Role of mucle stem cells in sarcomere addition and contractures
Dayanidhi, S. (PD/PI)
Shirley Ryan AbilityLab, National Institute of Child Health & Human Development (NICHD)
8/13/18 → 7/31/20
Project: Research project
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Muscle stem cell dysfunction in muscular contractures in children with cerebral palsy
Dayanidhi, S. (PD/PI)
Shirley Ryan AbilityLab, American Academy for Cerebral Palsy and Developmental Medicine
7/24/18 → 12/31/19
Project: Research project
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Mitochondrial etvsfunction and disabilit:), in PAD Project 2)
Dayanidhi, S. (Co-Investigator)
Northwestern University, American Heart Association
4/1/18 → 3/31/22
Project: Research project
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Ablation of satellite cell-specific clock gene, Bmal1, alters force production, muscle damage, and repair following contractile-induced injury
Kahn, R. E., Zhu, P., Roy, I., Peek, C., Hawley, J. A. & Dayanidhi, S., Jan 31 2025, In: FASEB Journal. 39, 2, e70325.Research output: Contribution to journal › Article › peer-review
Open Access -
Serum metabolomics after exercise in ambulatory individuals with cerebral palsy
Hanaoka, C., Pichika, R., Dayanidhi, S. & Jayabalan, P., May 2025, In: Developmental Medicine and Child Neurology. 67, 5, p. 639-647 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sex-specific preservation of neuromuscular function and metabolism following systemic transplantation of multipotent adult stem cells in a murine model of progeria
Thompson, S. D., Barrett, K. L., Rugel, C. L., Redmond, R., Rudofski, A., Kurian, J., Curtin, J. L., Dayanidhi, S. & Lavasani, M., Feb 2024, In: GeroScience. 46, 1, p. 1285-1302 18 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The ankle–brachial index, gastrocnemius mitochondrial respirometry, and walking performance in people with and without peripheral artery disease
McDermott, M. D. M., Dayanidhi, S., Leeuwenburgh, C., Wohlgemuth, S. E., Ferrucci, L., Peterson, C. A., Tian, L., Sufit, R. L., Zhao, L., Slysz, J., Polonsky, T. S., Guralnik, J. M., Kibbe, M. R., Ho, K. J., Criqui, M. H., Zhang, D., Xu, S. & Greenland, P., Dec 2024, In: Vascular Medicine (United Kingdom). 29, 6, p. 640-652 13 p.Research output: Contribution to journal › Article › peer-review
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Time-of-day effects on ex vivo muscle contractility following short-term satellite cell ablation
Kahn, R. E., Lieber, R. L., Meza, G., Dinnunhan, F., Lacham-Kaplan, O., Dayanidhi, S. & Hawley, J. A., Jul 1 2024, In: American Journal of Physiology. 327, 1, p. C213-C219Research output: Contribution to journal › Article › peer-review
3 Scopus citations
Datasets
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Cigarette smoking and mitochondrial dysfunction in peripheral artery disease
Guo, M. (Creator), McDermott, M. M. (Creator), Dayanidhi, S. (Creator), Leeuwenburgh, C. (Creator), Wohlgemuth, S. (Creator), Ferrucci, L. (Creator), Peterson, C. A. (Creator), Kosmac, K. (Creator), Tian, L. (Creator), Zhao, L. (Creator), Sufit, R. (Creator), Ho, K. (Creator), Criqui, M. (Creator), Xu, S. (Creator), Zhang, D. (Creator) & Greenland, P. (Creator), SAGE Journals, 2022
DOI: 10.25384/sage.c.6360467.v1, https://sage.figshare.com/collections/Cigarette_smoking_and_mitochondrial_dysfunction_in_peripheral_artery_disease/6360467/1
Dataset