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Sui Huang

  • 2809 Citations
1991 …2019
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Personal profile

Research Interests

Nucleolus, nucleus, chromatin, nuclear structure and function, cancer, growth-regulations, signal-transductions,

Training Experience

1997Postdoctoral Fellowship, Cold Spring Harbor Laboratory

Education/Academic qualification

PhD, Rutgers University

… → 1990

MD, Fudan University

… → 1982

Keywords

  • Cancer Biology
  • Cell Biology
  • Molecular Biology
  • Molecular Genetics
  • Nuclear Structure and Developmental Biology

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2001 2017

Magnetic Nanocomposites for Catheter-Directed Drug Delivery to Liver Tumors

Green, R., Huang, S., Kim, D. & Larson, A. C.

National Institute of Biomedical Imaging and Bioengineering

1/15/14 → 6/30/16

Project: Research project

Nanocomposites
Hepatocellular Carcinoma
Catheters
Liver
amonafide

The Structure and Function of Perinucleolar Compartment

Huang, S. & Li, L.

National Institute of General Medical Sciences

5/1/12 → 4/30/17

Project: Research project

Mechanisms of Nuclear Body Biogenesis

Huang, S.

Rosalind Franklin University of Medicine and Science, National Institute of General Medical Sciences

5/1/12 → 6/30/15

Project: Research project

The Structure and Function of Perinucleolar Compartment

Huang, S.

National Institute of General Medical Sciences

1/8/10 → 12/31/10

Project: Research project

A Novel HTP Assay for Identification of Compounds that Reduce PNC Prevalence

Huang, S.

National Institute of Mental Health

9/30/08 → 8/31/09

Project: Research project

Research Output 1991 2019

Chromosome conformation capture reveals two elements that interact with the PTBP3 (ROD1) transcription start site

Kubiak, M., Jurek, A., Kamińska, K., Kowalewski, J., Huang, S. & Lewandowska, M. A., Jan 1 2019, In : International journal of molecular sciences. 20, 2, 242.

Research output: Contribution to journal › Article

Polypyrimidine Tract-Binding Protein
Transcription Initiation Site
chromosomes
chromatin
Transcription
5 Citations (Scopus)

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

Frankowski, K. J., Wang, C., Patnaik, S., Schoenen, F. J., Southall, N., Li, D., Teper, Y., Sun, W., Kandela, I., Hu, D., Dextras, C., Knotts, Z., Bian, Y., Norton, J., Titus, S., Lewandowska, M. A., Wen, Y., Farley, K. I., Griner, L. M., Sultan, J. & 28 othersMeng, Z., Zhou, M., Vilimas, T., Powers, A. S., Kozlov, S., Nagashima, K., Quadri, H. S., Fang, M., Long, C., Khanolkar, O., Chen, W., Kang, J., Huang, H., Chow, E., Goldberg, E., Feldman, C., Xi, R., Kim, H. R., Sahagian, G., Baserga, S. J., Mazar, A., Ferrer, M., Zheng, W., Shilatifard, A., Aubé, J., Rudloff, U., Marugan, J. J. & Huang, S., May 16 2018, In : Science translational medicine. 10, 441, eaap8307.

Research output: Contribution to journal › Article

Neoplasm Metastasis
Neoplasms
RNA Polymerase I
Peptide Elongation Factors
Pancreatic Neoplasms

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras G12D/+ ;Tp53 R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer

Vilimas, T., Wang, A. Q., Patnaik, S., Hughes, E. A., Singleton, M. D., Knotts, Z., Li, D., Frankowski, K., Schlomer, J. J., Guerin, T. M., Springer, S., Drennan, C., Dextras, C., Wang, C., Gilbert, D., Southall, N., Ferrer, M., Huang, S., Kozlov, S., Marugan, J. & 2 othersXu, X. & Rudloff, U., Dec 1 2018, In : Cancer Chemotherapy and Pharmacology. 82, 6, p. 1067-1080 14 p.

Research output: Contribution to journal › Article

Pharmacokinetics
Pancreatic Neoplasms
Tumors
Area Under Curve
Pharmacodynamics
1 Citation (Scopus)

6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib

Liu, Y., Lou, G., Norton, J. T., Wang, C., Kandela, I., Tang, S., Shank, N. I., Gupta, P., Huang, M., Avram, M. J., Green, R., Mazar, A., Appella, D., Chen, Z. & Huang, S., Jan 1 2017, In : FASEB Journal. 31, 12, p. 5453-5465 13 p.

Research output: Contribution to journal › Article

Heterografts
Tumors
Hepatocellular Carcinoma
amonafide
Growth
16 Citations (Scopus)

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Rocchi, A., Yamamoto, S., Ting, T., Fan, Y., Sadleir, K., Wang, Y., Zhang, W., Huang, S., Levine, B., Vassar, R. & He, C., Aug 1 2017, In : PLoS Genetics. 13, 8, e1006962.

Research output: Contribution to journal › Article

autophagy
cognition
Autophagy
amyloid
Alzheimer disease