Grants per year
Personal profile
Research Interests
The Clare lab's current research interests include a) The utilization cells of the immune system, i.e., macrophages, to deliver nanoparticles for the treatment of primary and metastatic breast cancer, b) Progenitor cells and the development of the normal breast, and c) DNA mutation process in at risk breast tissue with a focus on APOBEC-mediated mutagenesis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Northwestern University
… → 1990
PhD, Northwestern University
… → 1988
Research interests keywords
- Breast Cancer
- Cancer Biology
- Genomics
- Microbiota
- Molecular Biology
- Nanotechnology
- Translational Research
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Lipid-initiated epigenetic reprogramming of the breast to a neural phenotype
Clare, S. E. (PD/PI) & Khan, S. A. (Co-Investigator)
3/10/25 → 2/28/27
Project: Research project
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Lipid metabolism, epigenetic reprogramming and ER neg. breast oncogenesis
Clare, S. E. (PD/PI)
American Association for Cancer Research
7/1/23 → 6/30/25
Project: Research project
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Comprehensive validation and commercial readiness of SpliceIO, a software platform for neoantigen discovery using RNA-seq data
Clare, S. E. (PD/PI), Clare, S. E. (PD/PI), Clare, S. E. (PD/PI), Khan, S. A. (Co-PD/PI), Khan, S. A. (Co-PD/PI) & Khan, S. A. (Co-PD/PI)
Envisagenics, Inc., National Cancer Institute
7/1/22 → 6/30/25
Project: Research project
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Research Project 3: Avon Foundation for Breast Cancer Research and Care Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Khan, S. A. (Co-PD/PI), Clare, S. E. (Co-Investigator) & Parker, J. B. (Co-Investigator)
Avon Breast Cancer Crusade LLC
10/1/17 → 12/31/18
Project: Research project
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Avon Foundation for Breast Cancer Research and Care Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Platanias, L. C. (PD/PI), Gius, D. R. (Co-PD/PI), Goel, M. (Co-PD/PI), Khan, S. A. (Co-PD/PI), Clare, S. E. (Co-Investigator), Gius, D. R. (Co-Investigator), Khan, S. A. (Co-Investigator) & Horikoshi, N. (Other)
Avon Breast Cancer Crusade LLC
10/1/17 → 12/31/18
Project: Research project
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Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system
Luo, Y., Mao, C., Sanchez-Pinto, L. N., Ahmad, F. S., Naidech, A., Rasmussen, L., Pacheco, J. A., Schneider, D., Mithal, L. B., Dresden, S., Holmes, K., Carson, M., Shah, S. J., Khan, S., Clare, S., Wunderink, R. G., Liu, H., Walunas, T., Cooper, L. & Yue, F. & 14 others, , Jul 2024, In: Learning Health Systems. 8, 3, e10417.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Author Correction: Lipid exposure activates gene expression changes associated with estrogen receptor negative breast cancer (npj Breast Cancer, (2022), 8, 1, (59), 10.1038/s41523-022-00422-0)
Yadav, S., Virk, R., Chung, C. H., Eduardo, M. B., VanDerway, D., Chen, D., Burdett, K., Gao, H., Zeng, Z., Ranjan, M., Cottone, G., Xuei, X., Chandrasekaran, S., Backman, V., Chatterton, R., Khan, S. & Clare, S. E., Dec 2023, In: npj Breast Cancer. 9, 1, 11.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women’s breast tissue
Hajirahimkhan, A., Howell, C., Bartom, E. T., Dong, H., Lantvit, D. D., Xuei, X., Chen, S. N., Pauli, G. F., Bolton, J. L., Clare, S. E., Khan, S. A. & Dietz, B. M., Dec 2023, In: Scientific reports. 13, 1, 8734.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Lipid exposure activates gene expression changes associated with estrogen receptor negative breast cancer
Yadav, S., Virk, R., Chung, C. H., Eduardo, M. B., VanDerway, D., Chen, D., Burdett, K., Gao, H., Zeng, Z., Ranjan, M., Cottone, G., Xuei, X., Chandrasekaran, S., Backman, V., Chatterton, R., Khan, S. A. & Clare, S. E., Dec 2022, In: npj Breast Cancer. 8, 1, 59.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Deep learning for cancer type classification and driver gene identification
Zeng, Z., Mao, C., Vo, A., Li, X., Nugent, J. O., Khan, S. A., Clare, S. E. & Luo, Y., Oct 2021, In: BMC bioinformatics. 22, 491.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations
Datasets
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Additional file 15 of Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.15102496, https://springernature.figshare.com/articles/dataset/Additional_file_15_of_Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/15102496
Dataset
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MOESM10 of BRCA1 mutation influences progesterone response in human benign mammary organoids
Davaadelger, B. (Contributor), Choi, M.-R. (Creator), Singhal, H. (Creator), Clare, S. E. (Creator), Khan, S. A. (Creator) & Kim, J. J. (Contributor), figshare, 2019
DOI: 10.6084/m9.figshare.11273291, https://springernature.figshare.com/articles/MOESM10_of_BRCA1_mutation_influences_progesterone_response_in_human_benign_mammary_organoids/11273291
Dataset
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Additional file 6: Figure S3 of Progesterone receptor blockade in human breast cancer cells decreases cell cycle progression through G2/M by repressing G2/M genes
Clare, S. E. (Creator), Gupta, A. (Creator), Choi, M. (Creator), Ranjan, M. (Creator), Lee, O. (Contributor), Wang, J. (Creator), Ivancic, D. Z. (Creator), Kim, J. J. (Contributor) & Khan, S. A. (Creator), figshare, 2016
DOI: 10.6084/m9.figshare.c.3596489_d4, https://springernature.figshare.com/articles/presentation/Additional_file_6_Figure_S3_of_Progesterone_receptor_blockade_in_human_breast_cancer_cells_decreases_cell_cycle_progression_through_G2_M_by_repressing_G2_M_genes/4318829
Dataset
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Additional file 7 of Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.15102541, https://springernature.figshare.com/articles/dataset/Additional_file_7_of_Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/15102541
Dataset
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Additional file 20 of Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland
Ranjan, M. (Creator), Lee, O. (Creator), Cottone, G. (Creator), Mirzaei Mehrabad, E. (Creator), Spike, B. T. (Creator), Zeng, Z. (Creator), Yadav, S. (Creator), Chatterton, R. (Creator), Kim, J. J. (Creator), Clare, S. E. (Creator) & Khan, S. A. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.15102514, https://springernature.figshare.com/articles/dataset/Additional_file_20_of_Progesterone_receptor_antagonists_reverse_stem_cell_expansion_and_the_paracrine_effectors_of_progesterone_action_in_the_mouse_mammary_gland/15102514
Dataset