Grants per year
Personal profile
Research Interests
My clinical and research focus is cystic fibrosis. My research interests are developing new therapies, characterizing and treating early lung disease, and reducing outcomes disparities by identifying and treating children who are at higher risk for adverse outcomes. I am active in healthcare quality improvement at the practice and national level. Since newborn screening in cystic fibrosis has been established in the United States, I have been especially interested in refining care of the newly diagnosed infant and their family, and in bringing highly effective therapies into the care of infants. On the other end of the spectrum of pediatrics, I am engaged in research and program development in transition from pediatric to adult health care environments.
My major academic focus is therapeutic clinical trials. I also evaluate risk factors and health care system processes that contribute to disparate outcomes in cystic fibrosis. In my research leadership role, I enable trials in childhood-onset conditions.
I specialize in pediatric lung disease, focusing on diagnosis and treatment of children with cystic fibrosis.
Certifications and Licenses
Pediatric Pulmonology |
Training Experience
1988 | Residency, Johns Hopkins Hospital |
1991 | Fellowship, Johns Hopkins Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Northwestern University
… → 1985
Research interests keywords
- Cystic Fibrosis
- Health Disparities
- Healthcare Quality
- Pediatrics
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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NUCATS T32
McColley, S. A. (PD/PI), Scott, E. A. (PD/PI), Gollan, J. K. (Co-PD/PI) & Helseth, S. A. (Co-Investigator)
National Center for Advancing Translational Sciences
9/15/24 → 7/31/29
Project: Research project
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VX19-809-124: A Phase 3, Open-label, and Rollover Study to Evaluate the Long-term Safety and Tolerability of Lumacaftor/Ivacaftor Treatment in Subjects With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation
McColley, S. A. (PD/PI)
Vertex Pharmaceuticals Incorporated
2/21/20 → 8/31/50
Project: Research project
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VX19-445-107: A Phase 3, Open-label Study Evaluating theLong-term Safety and Efficacy of VX-445/TEZ/IVACombination Therapy in Subjects With CysticFibrosis Who Are 6 Years of Age and Older
McColley, S. A. (PD/PI)
Vertex Pharmaceuticals Incorporated, Ann & Robert H. Lurie Children's Hospital of Chicago
2/19/20 → 8/31/50
Project: Research project
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Childcare costs with no F&A.
McColley, S. A. (PD/PI) & McColley, S. A. (PD/PI)
National Center for Advancing Translational Sciences
7/15/19 → 6/30/25
Project: Research project
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Global Representation Matters: Publishing Innovations to Support Authors From Less Resourced Environments
McColley, S. A., Mar 2025, In: Pediatric Pulmonology. 60, S1, p. S111-S113Research output: Contribution to journal › Review article › peer-review
Open Access -
422.1Extrapulmonary Diseases with Pulmonary Manifestations
Griffiths, A. G., Palla, J. & McColley, S. A., Jan 1 2024, Nelson Textbook of Pediatrics: Volume 1-2. Elsevier, p. 2526-2531 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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ALPINE2: Efficacy and safety of 14-day vs 28-day inhaled aztreonam for Pa eradication in children with cystic fibrosis
ALPINE2 study investigators, Jan 2024, In: Journal of Cystic Fibrosis. 23, 1, p. 80-86 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A skin-interfaced, miniaturized platform for triggered induction, capture and colorimetric multicomponent analysis of microliter volumes of sweat
Kim, J., Oh, S., Yang, D. S., Rugg, L., Mathur, R., Kwak, S. S., Yoo, S., Li, S., Kanatzidis, E. E., Lee, G., Yoon, H. J., Huang, Y., Ghaffari, R., McColley, S. A. & Rogers, J. A., Jun 1 2024, In: Biosensors and Bioelectronics. 253, 116166.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Development of a Miniaturized Mechanoacoustic Sensor for Continuous, Objective Cough Detection, Characterization and Physiologic Monitoring in Children with Cystic Fibrosis
Tzavelis, A., Palla, J., Mathur, R., Bedford, B., Wu, Y. H., Trueb, J., Shin, H. S., Arafa, H., Jeong, H., Ouyang, W., Kwak, J. Y., Chiang, J., Schulz, S., Carter, T. M., Rangaraj, V., Katsaggelos, A. K., McColley, S. A. & Rogers, J. A., 2024, In: IEEE Journal of Biomedical and Health Informatics. 28, 10, p. 5941-5952 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations