• 259 Citations
20122021
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Research Output 2012 2019

  • 259 Citations
  • 18 Article
  • 2 Letter
  • 1 Comment/debate
2019

Activated microglia in cortical white matter across cognitive aging trajectories

Gefen, T., Kim, G., Bolbolan, K., Geoly, A., Ohm, D., Oboudiyat, C., Shahidehpour, R., Rademaker, A., Weintraub, S., Bigio, E. H., Marsel Mesulam, M., Rogalski, E. & Geula, C., Jan 1 2019, In : Frontiers in Aging Neuroscience. 11, MAY, 094.

Research output: Contribution to journalArticle

Open Access
Microglia
Inflammation Mediators
Gliosis
HLA Antigens
Cognitive Aging
8 Citations (Scopus)

Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases

Rogalski, E., Gefen, T. D., Mao, Q., Connelly, M., Weintraub, S., Geula, C., Bigio, E. H. & Mesulam, M-M., May 1 2019, In : Hippocampus. 29, 5, p. 458-467 10 p.

Research output: Contribution to journalArticle

Episodic Memory
Personality
Autopsy
Entorhinal Cortex
Neocortex
2 Citations (Scopus)

Cortical cholinergic denervation in primary progressive aphasia with Alzheimer pathology

Mesulam, M-M., Lalehzari, N., Rahmani, F., Ohm, D., Shahidehpour, R., Kim, G., Gefen, T. D., Weintraub, S., Bigio, E. H. & Geula, C., Apr 2 2019, In : Neurology. 92, 14, p. E1580-E1588

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Denervation
Cholinergic Agents
Pathology
Cholinergic Neurons

FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology

Mao, Q., Zheng, X., Gefen, T. D., Rogalski, E., Spencer, C. L., Rademakers, R., Fought, A. J., Kohler, M., Weintraub, S., Xia, H., Mesulam, M-M. & Bigio, E. H., Sep 1 2019, In : Journal of neuropathology and experimental neurology. 78, 9, p. 844-853 10 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Pathology
Haploinsufficiency
Mutation
Frontotemporal Lobar Degeneration

Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia

Kim, G., Bolbolan, K., Shahidehpour, R., Jamshidi, P., Gefen, T. D., Ayala, I. A., Weintraub, S., Bigio, E. H., Mesulam, M-M. & Geula, C., Mar 1 2019, In : Journal of neuropathology and experimental neurology. 78, 3, p. 229-237 9 p.

Research output: Contribution to journalArticle

National Institute on Aging (U.S.)
Primary Progressive Aphasia
National Institute on Deafness and Other Communication Disorders (U.S.)
Language
National Institute of Neurological Disorders and Stroke

Neuropathologic basis of in vivo cortical atrophy in the aphasic variant of Alzheimer's disease

Ohm, D. T., Fought, A. J., Rademaker, A., Kim, G., Sridhar, J., Coventry, C., Gefen, T., Weintraub, S., Bigio, E., Mesulam, M. M., Rogalski, E. & Geula, C., Jan 1 2019, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle

Neurofibrillary Tangles
Primary Progressive Aphasia
Atrophy
Alzheimer Disease
Language
3 Citations (Scopus)
Primary Progressive Aphasia
Microglia
Atrophy
Language
Frontotemporal Lobar Degeneration
1 Citation (Scopus)

Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes

Nishihira, Y., Gefen, T. D., Mao, Q., Appin, C. L., Kohler, M., Walker, J., Rademakers, R., Rademaker, A. W., Rogalski, E., Weintraub, S., Geula, C., Mesulam, M-M. & Bigio, E. H., Jul 1 2019, In : Acta Neuropathologica. 138, 1, p. 167-169 3 p.

Research output: Contribution to journalLetter

Frontotemporal Dementia
Pathology
3 Citations (Scopus)

Word comprehension in temporal cortex and Wernicke area: A PPA perspective

Mesulam, M. M., Rader, B. M., Sridhar, J., Nelson, M. J., Hyun, J., Rademaker, A., Geula, C., Bigio, E. H., Thompson, C. K., Gefen, T. D., Weintraub, S. & Rogalski, E. J., Jan 15 2019, In : Neurology. 92, 3, p. E224-E233

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Temporal Lobe
Wernicke Area
Patient Rights
Neurodegenerative Diseases
2018
3 Citations (Scopus)

Asymmetric TDP pathology in primary progressive aphasia with right hemisphere language dominance

Kim, G., Vahedi, S., Gefen, T., Weintraub, S., Bigio, E. H., Mesulam, M. M. & Geula, C., Jan 30 2018, In : Neurology. 90, 5, p. e396-e403

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Language
Microglia
Pathology
Atrophy
1 Citation (Scopus)
Primary Progressive Aphasia
DNA-Binding Proteins
Atrophy
Microglia
Phenotype
1 Citation (Scopus)

Combined pathologies in FTLD-TDP types A and C

Gefen, T. D., Ahmadian, S. S., Mao, Q., Kim, G., Seckin, M., Bonakdarpour, B., Ramos, E. M., Coppola, G., Rademakers, R., Rogalski, E., Rademaker, A. W., Weintraub, S., Mesulam, M-M., Geula, C. & Bigio, E. H., May 1 2018, In : Journal of neuropathology and experimental neurology. 77, 5, p. 405-412 8 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Pathology
Frontotemporal Lobar Degeneration
Primary Progressive Aphasia
Mutation
9 Citations (Scopus)
Pyramidal Cells
Acetylcholinesterase
Human Activities
Neurons
Staining and Labeling
9 Citations (Scopus)

Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer's disease

Gefen, T. D., Papastefan, S. T., Rezvanian, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M-M. & Geula, C., Feb 1 2018, In : Cortex. 99, p. 69-77 9 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Alzheimer Disease
Neurons
Neurofibrillary Tangles
Aptitude
2017
4 Citations (Scopus)

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M., May 1 2017, In : Alzheimer's and Dementia. 13, 5, p. 598-601 4 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Dementia
Alzheimer Disease
Pathology
Amyloid
2015
41 Citations (Scopus)

Morphometric and Histologic Substrates of Cingulate Integrity in Elders with Exceptional Memory Capacity

Gefen, T., Peterson, M., Papastefan, S. T., Martersteck, A., Whitney, K., Rademaker, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M. M. & Geula, C., Jan 28 2015, In : Journal of Neuroscience. 35, 4, p. 1781-1791 11 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Neurons
Neurofibrillary Tangles
Episodic Memory
Neuroimaging

Neurobiological substrates of super aging and the preservation of cingulate cortex

Gefen, T. D., Dec 1 2015, In : Rejuvenation Research. 18, 6, p. 589-590 2 p.

Research output: Contribution to journalComment/debate

Gyrus Cinguli
2014
23 Citations (Scopus)

Longitudinal neuropsychological performance of cognitive SuperAgers

Gefen, T., Shaw, E., Whitney, K., Martersteck, A., Stratton, J., Rademaker, A., Weintraub, S., Mesulam, M. M. & Rogalski, E., Jan 1 2014, In : Journal of the American Geriatrics Society. 62, 8, p. 1598-1600 3 p.

Research output: Contribution to journalLetter

Neuropsychological Tests
Short-Term Memory
Cognition
Biomarkers
2013
31 Citations (Scopus)

Naming vs knowing faces in primary progressive aphasia: A tale of 2 hemispheres

Gefen, T., Wieneke, C., Martersteck, A., Whitney, K., Weintraub, S., Mesulam, M. M. & Rogalski, E., Aug 13 2013, In : Neurology. 81, 7, p. 658-664 7 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Atrophy
Dementia
Temporal Lobe
Language
41 Citations (Scopus)
Apolipoprotein E4
Episodic Memory
Gyrus Cinguli
Biological Factors
Gene Frequency
2012
79 Citations (Scopus)

Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia

Gefen, T., Gasho, K., Rademaker, A., Lalehzari, M., Weintraub, S., Rogalski, E., Wieneke, C., Bigio, E., Geula, C. & Mesulam, M. M., Jan 1 2012, In : Brain. 135, 5, p. 1554-1565 12 p.

Research output: Contribution to journalArticle

Primary Progressive Aphasia
Dementia
Pathology
Language
Phenotype