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  • 2012

    Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program

    Pollin, T. I., Isakova, T., Jablonski, K. A., de Bakker, P. I. W., Taylor, A., McAteer, J., Pan, Q., Horton, E. S., Delahanty, L. M., Altshuler, D., Shuldiner, A. R., Goldberg, R. B., Florez, J. C., Franks, P. W., Bray, G. A., Culbert, I. W., Champagne, C. M., Eberhardt, B., Greenway, F., Guillory, F. G. & 419 others, Herbert, A. A., Jeffirs, M. L., Kennedy, B. M., Lovejoy, J. C., Morris, L. H., Melancon, L. E., Ryan, D., Sanford, D. A., Smith, K. G., Smith, L. L., St. Amant, J. A., Tulley, R. T., Vicknair, P. C., Williamson, D., Zachwieja, J. J., Polonsky, K. S., Tobian, J., Ehrmann, D., Matulik, M. J., Clark, B., Czech, K., DeSandre, C., Hilbrich, R., McNabb, W., Semenske, A. R., Caro, J. F., Watson, P. G., Goldstein, B. J., Smith, K. A., Mendoza, J., Liberoni, R., Pepe, C., Spandorfer, J., Donahue, R. P., Goldberg, R. B., Prineas, R., Rowe, P., Calles, J., Cassanova-Romero, P., Florez, H. J., Giannella, A., Kirby, L., Larreal, C., McLymont, V., Mendez, J., Ojito, J., Perry, A., Saab, P., Haffner, S. M., Montez, M. G., Lorenzo, C., Martinez, A., Hamman, R. F., Nash, P. V., Testaverde, L., Anderson, D. R., Ballonoff, L. B., Bouffard, A., Calonge, B. N., Delve, L., Farago, M., Hill, J. O., Hoyer, S. R., Jortberg, B. T., Lenz, D., Miller, M., Price, D. W., Regensteiner, J. G., Seagle, H., Smith, C. M., Steinke, S. C., VanDorsten, B., Horton, E. S., Lawton, K. E., Arky, R. A., Bryant, M., Burke, J. P., Caballero, E., Callaphan, K. M., Ganda, O. P., Franklin, T., Jackson, S. D., Jacobsen, A. M., Jacobsen, A. M., Kula, L. M., Kocal, M., Malloy, M. A., Nicosia, M., Oldmixon, C. F., Pan, J., Quitingon, M., Rubtchinsky, S., Seely, E. W., Schweizer, D., Simonson, D., Smith, F., Solomon, C. G., Warram, J., Kahn, S. E., Montgomery, B. K., Fujimoto, W., Knopp, R. H., Lipkin, E. W., Marr, M., Trence, D., Kitabchi, A. E., Murphy, M. E., Applegate, W. B., Bryer-Ash, M., Frieson, S. L., Imseis, R., Lambeth, H., Lichtermann, L. C., Oktaei, H., Rutledge, L. M. K., Sherman, A. R., Smith, C. M., Soberman, J. E., Williams-Cleaves, B., Metzger, B. E., Johnson, M. K., Behrends, C., Cook, M., Fitzgibbon, M., Giles, M. M., Heard, D., Johnson, C. K. H., Larsen, D., Lowe, A., Lyman, M., McPherson, D., Molitch, M. E., Pitts, T., Reinhart, R., Roston, S., Schinleber, P. A., Nathan, D. M., McKitrick, C., Turgeon, H., Abbott, K., Anderson, E., Bissett, L., Cagliero, E., Florez, J. C., Delahanty, L., Goldman, V., Poulos, A., Olefsky, J. M., Carrion-Petersen, M. L., Barrett-Connor, E., Edelman, S. V., Henry, R. R., Horne, J., Janesch, S. S., Leos, D., Mudaliar, S., Polonsky, W., Smith, J., Vejvoda, K., Pi-Sunyer, F. X., Lee, J. E., Allison, D. B., Aronoff, N. J., Crandall, J. P., Foo, S. T., Pal, C., Parkes, K., Pena, M. B., Rooney, E. S., van Wye, G. E. H., Viscovich, K. A., Marrero, D. G., Prince, M. J., Kelly, S. M., Dotson, Y. F., Fineberg, E. S., Guare, J. C., Hadden, A. M., Ignaut, J. M., Jackson, M. L., Kirkman, M. S., Mather, K. J., Porter, B. D., Roach, P. J., Rowland, N. D., Wheeler, M. L., Ratner, R. E., Youssef, G., Shapiro, S., Bavido-Arrage, C., Boggs, G., Bronsord, M., Brown, E., Cheatham, W. W., Cola, S., Evans, C., Gibbs, P., Kellum, T., Levatan, C., Nair, A. K., Passaro, M., Uwaifo, G., Saad, M. F., Budget, M., Jinagouda, S., Akbar, K., Conzues, C., Magpuri, P., Ngo, K., Rassam, A., Waters, D., Xapthalamous, K., Santiago, J. V., Dagogo-Jack, S., White, N. H., Das, S., Santiago, A., Brown, A., Fisher, E., Hurt, E., Jones, T., Kerr, M., Ryder, L., Wernimont, C., Saudek, C. D., Bradley, V., Sullivan, E., Whittington, T., Abbas, C., Brancati, F. L., Clark, J. M., Charleston, J. B., Freel, J., Horak, K., Jiggetts, D., Johnson, D., Joseph, H., Loman, K., Mosley, H., Rubin, R. R., Samuels, A., Stewart, K. J., Williamson, P., Schade, D. S., Adams, K. S., Johannes, C., Atler, L. F., Boyle, P. J., Burge, M. R., Canady, J. L., Chai, L., Gonzales, Y., Hernandez-McGinnis, D. A., Katz, P., King, C., Rassam, A., Rubinchik, S., Senter, W., Waters, D., Shamoon, H., Brown, J. O., Adorno, E., Cox, L., Crandall, J., Duffy, H., Engel, S., Friedler, A., Howard-Century, C. J., Kloiber, S., Longchamp, N., Martinez, H., Pompi, D., Scheindlin, J., Violino, E., Walker, E., Wylie-Rosett, J., Zimmerman, E., Zonszein, J., Orchard, T., Wing, R. R., Koenning, G., Kramer, M. K., Barr, S., Boraz, M., Clifford, L., Culyba, R., Frazier, M., Gilligan, R., Harrier, S., Harris, L., Jeffries, S., Kriska, A., Manjoo, Q., Mullen, M., Noel, A., Otto, A., Semler, L., Smith, C. F., Smith, M., Venditti, E., Weinzierl, V., Williams, K. V., Wilson, T., Arakaki, R. F., Latimer, R. W., Baker-Ladao, N. K., Beddow, R., Dias, L., Inouye, J., Mau, M. K., Mikami, K., Mohideen, P., Odom, S. K., Perry, R. U., Knowler, W. C., Cooeyate, N., Hoskin, M. A., Percy, C. A., Acton, K. J., Andre, V. L., Barber, R., Begay, S., Bennett, P. H., Benson, M. B., Bird, E. C., Broussard, B. A., Chavez, M., Dacawyma, T., Doughty, M. S., Duncan, R., Edgerton, C., Ghahate, J. M., Glass, J., Glass, M., Gohdes, D., Grant, W., Hanson, R. L., Horse, E., Ingraham, L. E., Jackson, M., Jay, P., Kaskalla, R. S., Kessler, D., Kobus, K. M., Krakoff, J., Manus, C., Michaels, S., Morgan, T., Nashboo, Y., Nelson, J. A., Poirier, S., Polczynski, E., Reidy, M., Roumain, J., Rowse, D., Sangster, S., Sewenemewa, J., Tonemah, D., Wilson, C., Yazzie, M., Bain, R., Fowler, S., Brenneman, T., Abebe, S., Bamdad, J., Callaghan, J., Edelstein, S. L., Gao, Y., Grimes, K. L., Grover, N., Haffner, L., Jones, S., Jones, T. L., Katz, R., Lachin, J. M., Mucik, P., Orlosky, R., Rochon, J., Sapozhnikova, A., Sherif, H., Stimpson, C., Temprosa, M., Walker-Murray, F., Marcovina, S., Strylewicz, G., Aldrich, F. A., O'Leary, D., Stamm, E., Rautaharju, P., Prineas, R. J., Alexander, T., Campbell, C., Hall, S., Li, Y., Mills, M., Pemberton, N., Rautaharju, F., Zhang, Z., Mayer-Davis, E., Moran, R. R., Ganiats, T., David, K., Sarkin, A. J., Eastman, R., Fradkin, J., Garfield, S., Gregg, E., Zhang, P., Herman, W., Florez, J. C., Altshuler, D., de Bakker, P. I. W., Franks, P. W., Hanson, R. L., Jablonski, K., Knowler, W. C., McAteer, J. B., Pollin, T. I. & Shuldiner, A. R., Aug 2012, In: PLoS genetics. 8, 8, e1002895.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

    Sandholm, N., Salem, R. M., McKnight, A. J., Brennan, E. P., Forsblom, C., Isakova, T., McKay, G. J., Williams, W. W., Sadlier, D. M., Mäkinen, V. P., Swan, E. J., Palmer, C., Boright, A. P., Ahlqvist, E., Deshmukh, H. A., Keller, B. J., Huang, H., Ahola, A. J., Fagerholm, E., Gordin, D. & 73 others, Harjutsalo, V., He, B., Heikkilä, O., Hietala, K., Kytö, J., Lahermo, P., Lehto, M., Lithovius, R., Österholm, A. M., Parkkonen, M., Pitkäniemi, J., Rosengård-Bärlund, M., Saraheimo, M., Sarti, C., Söderlund, J., Soro-Paavonen, A., Syreeni, A., Thorn, L. M., Tikkanen, H., Tolonen, N., Tryggvason, K., Tuomilehto, J., Wadén, J., Gill, G. V., Prior, S., Guiducci, C., Mirel, D. B., Taylor, A., Hosseini, S. M., Parving, H. H., Rossing, P., Tarnow, L., Ladenvall, C., Alhenc-Gelas, F., Lefebvre, P., Rigalleau, V., Roussel, R., Tregouet, D. A., Maestroni, A., Maestroni, S., Falhammar, H., Gu, T., Möllsten, A., Cimponeriu, D., Ioana, M., Mota, M., Mota, E., Serafinceanu, C., Stavarachi, M., Hanson, R. L., Nelson, R. G., Kretzler, M., Colhoun, H. M., Panduru, N. M., Gu, H. F., Brismar, K., Zerbini, G., Hadjadj, S., Marre, M., Groop, L., Lajer, M., Bull, S. B., Waggott, D., Paterson, A. D., Savage, D. A., Bain, S. C., Martin, F., Hirschhorn, J. N., Godson, C., Florez, J. C., Groop, P. H., Maxwell, A. P. & Böger, C. A., Sep 2012, In: PLoS genetics. 8, 9, e1002921.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    168 Scopus citations
  • 2011

    Diuretics, calciuria and secondary hyperparathyroidism in the Chronic Renal Insufficiency Cohort

    Isakova, T., Anderson, C. A. M., Leonard, M. B., Xie, D., Gutiérrez, O. M., Rosen, L. K., Theurer, J., Bellovich, K., Steigerwalt, S. P., Tang, I., Anderson, A. H., Townsend, R. R., He, J., Feldman, H. I. & Wolf, M., Apr 2011, In: Nephrology Dialysis Transplantation. 26, 4, p. 1258-1265 8 p.

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations
  • FGF23 induces left ventricular hypertrophy

    Faul, C., Amaral, A. P., Oskouei, B., Hu, M. C., Sloan, A., Isakova, T., Gutiérrez, O. M., Aguillon-Prada, R., Lincoln, J., Hare, J. M., Mundel, P., Morales, A., Scialla, J., Fischer, M., Soliman, E. Z., Chen, J., Go, A. S., Rosas, S. E., Nessel, L., Townsend, R. R. & 15 others, Feldman, H. I., Sutton, M. S. J., Ojo, A., Gadegbeku, C., Di Marco, G. S., Reuter, S., Kentrup, D., Tiemann, K., Brand, M., Hill, J. A., Moe, O. W., Kuro-o, M., Kusek, J. W., Keane, M. G. & Wolf, M., Nov 1 2011, In: Journal of Clinical Investigation. 121, 11, p. 4393-4408 16 p.

    Research output: Contribution to journalArticlepeer-review

    1387 Scopus citations
  • Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease

    Isakova, T., Xie, H., Yang, W., Xie, D., Anderson, A. H., Scialla, J., Wahl, P., Gutiérrez, O. M., Steigerwalt, S., He, J., Schwartz, S., Lo, J., Ojo, A., Sondheimer, J., Hsu, C. Y., Lash, J., Leonard, M., Kusek, J. W., Feldman, H. I. & Wolf, M., Jun 15 2011, In: JAMA - Journal of the American Medical Association. 305, 23, p. 2432-2439 8 p.

    Research output: Contribution to journalArticlepeer-review

    772 Scopus citations
  • Fibroblast growth factor 23 in patients undergoing peritoneal dialysis

    Isakova, T., Xie, H., Barchi-Chung, A., Varga, G., Sowden, N., Houston, J., Wahl, P., Lundquist, A., Epstein, M., Smith, K., Contreras, G., Ortega, L., Lenz, O., Briones, P., Egbert, P., Ikizler, T. A., Jueppner, H. & Wolf, M., Nov 1 2011, In: Clinical Journal of the American Society of Nephrology. 6, 11, p. 2688-2695 8 p.

    Research output: Contribution to journalArticlepeer-review

    67 Scopus citations
  • Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

    Isakova, T., Wahl, P., Vargas, G. S., Gutiérrez, O. M., Scialla, J., Xie, H., Appleby, D., Nessel, L., Bellovich, K., Chen, J., Hamm, L., Gadegbeku, C., Horwitz, E., Townsend, R. R., Anderson, C. A. M., Lash, J. P., Hsu, C. Y., Leonard, M. B. & Wolf, M., Jun 2011, In: Kidney international. 79, 12, p. 1370-1378 9 p.

    Research output: Contribution to journalArticlepeer-review

    846 Scopus citations
  • Hepcidin and disordered mineral metabolism in chronic kidney disease

    Carvalho, C., Isakova, T., Collerone, G., Olbina, G., Wolf, M., Westerman, M. & Gutiérrez, O. M., Aug 2011, In: Clinical Nephrology. 76, 2, p. 90-98 9 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Impact of Poverty on Serum Phosphate Concentrations in the Third National Health and Nutrition Examination Survey

    Gutiérrez, O. M., Isakova, T., Enfield, G. & Wolf, M., Mar 2011, In: Journal of Renal Nutrition. 21, 2, p. 140-148 9 p.

    Research output: Contribution to journalArticlepeer-review

    32 Scopus citations
  • Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease

    Isakova, T., Gutirrez, O. M., Smith, K., Epstein, M., Keating, L. K., Jppner, H. & Wolf, M., Feb 2011, In: Nephrology Dialysis Transplantation. 26, 2, p. 584-591 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    143 Scopus citations
  • Vitamin D Deficiency, Inflammation, and Albuminuria in Chronic Kidney Disease: Complex Interactions

    Isakova, T., Gutiérrez, O. M., Patel, N. M., Andress, D. L., Wolf, M. & Levin, A., Jul 2011, In: Journal of Renal Nutrition. 21, 4, p. 295-302 8 p.

    Research output: Contribution to journalArticlepeer-review

    65 Scopus citations
  • 2010

    Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active

    Shimada, T., Urakawa, I., Isakova, T., Yamazaki, Y., Epstein, M., Wesseling-Perry, K., Wolf, M., Salusky, I. B. & Jüppner, H., Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 578-585 8 p.

    Research output: Contribution to journalArticlepeer-review

    174 Scopus citations
  • Low socioeconomic status associates with higher serum phosphate irrespective of race

    Gutiérrez, O. M., Anderson, C., Isakova, T., Scialla, J., Negrea, L., Anderson, A. H., Bellovich, K., Chen, J., Robinson, N., Ojo, A., Lash, J., Feldman, H. I. & Wolf, M., Nov 2010, In: Journal of the American Society of Nephrology. 21, 11, p. 1953-1960 8 p.

    Research output: Contribution to journalArticlepeer-review

    81 Scopus citations
  • Racial differences in postprandial mineral ion handling in health and in chronic kidney disease

    Gutiérrez, O. M., Isakova, T., Smith, K., Epstein, M., Patel, N. & Wolf, M., Dec 2010, In: Nephrology Dialysis Transplantation. 25, 12, p. 3970-3977 8 p.

    Research output: Contribution to journalArticlepeer-review

    32 Scopus citations
  • 2009

    Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease

    Gutiérrez, O. M., Januzzi, J. L., Isakova, T., Laliberte, K., Smith, K., Collerone, G., Sarwar, A., Hoffmann, U., Coglianese, E., Christenson, R., Wang, T. J., DeFilippi, C. & Wolf, M., May 19 2009, In: Circulation. 119, 19, p. 2545-2552 8 p.

    Research output: Contribution to journalArticlepeer-review

    651 Scopus citations
  • Klotho variants and chronic hemodialysis mortality

    Friedman, D. J., Afkarian, M., Tamez, H., Bhan, I., Isakova, T., Wolf, M., Ankers, E., Ye, J., Tonelli, M., Zoccali, C., Kuro-o, M., Moe, O., Karumanchi, S. A. & Thadhani, R., Nov 2009, In: Journal of Bone and Mineral Research. 24, 11, p. 1847-1855 9 p.

    Research output: Contribution to journalArticlepeer-review

    51 Scopus citations
  • Phosphorus binders and survival on hemodialysis

    Isakova, T., Gutierrez, O. M., Chang, Y., Shah, A., Tamez, H., Smith, K., Thadhani, R. & Wolf, M., Feb 2009, In: Journal of the American Society of Nephrology. 20, 2, p. 388-396 9 p.

    Research output: Contribution to journalArticlepeer-review

    299 Scopus citations
  • Plasma gelsolin and circulating actin correlate with hemodialysis mortality

    Lee, P. S., Sampath, K., Karumanchi, S. A., Tamez, H., Bhan, I., Isakova, T., Gutierrez, O. M., Wolf, M., Chang, Y., Stossel, T. P. & Thadhani, R., May 2009, In: Journal of the American Society of Nephrology. 20, 5, p. 1140-1148 9 p.

    Research output: Contribution to journalArticlepeer-review

    94 Scopus citations
  • 2008

    Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis

    Gutiérrez, O. M., Mannstadt, M., Isakova, T., Rauh-Hain, J. A., Tamez, H., Shah, A., Smith, K., Lee, H., Thadhani, R., Jüppner, H. & Wolf, M., Aug 7 2008, In: New England Journal of Medicine. 359, 6, p. 584-592 9 p.

    Research output: Contribution to journalArticlepeer-review

    1354 Scopus citations
  • Postprandial mineral metabolism and secondary hyperparathyroidism in early CKD

    Isakova, T., Gutierrez, O., Shah, A., Castaldo, L., Holmes, J., Lee, H. & Wolf, M., Mar 2008, In: Journal of the American Society of Nephrology. 19, 3, p. 615-623 9 p.

    Research output: Contribution to journalArticlepeer-review

    130 Scopus citations
  • Prevalence and severity of disordered mineral metabolism in Blacks with chronic kidney disease

    Gutiérrez, O. M., Isakova, T., Andress, D. L., Levin, A. & Wolf, M., Apr 2008, In: Kidney international. 73, 8, p. 956-962 7 p.

    Research output: Contribution to journalArticlepeer-review

    57 Scopus citations
  • 2006

    Post-transplant hypophosphatemia: Tertiary 'Hyper-Phosphatoninism'?

    Bhan, I., Shah, A., Holmes, J., Isakova, T., Gutierrez, O., Burnett, S. A., Jüppner, H. & Wolf, M., Oct 2006, In: Kidney international. 70, 8, p. 1486-1494 9 p.

    Research output: Contribution to journalArticlepeer-review

    154 Scopus citations
  • 2005

    Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease

    Gutierrez, O., Isakova, T., Rhee, E., Shah, A., Holmes, J., Collerone, G., Jüppner, H. & Wolf, M., 2005, In: Journal of the American Society of Nephrology. 16, 7, p. 2205-2215 11 p.

    Research output: Contribution to journalArticlepeer-review

    716 Scopus citations