Grants per year
Personal profile
Research Interests
Dr Simuni joined the faculty of the Northwestern University Feinberg school of Medicine in 2000 to build and lead a multidisciplinary movement disorders center that is recognized by the National Parkinson’s Foundation as a Center of Excellence and serves as a training model in the region. Her research interests are focused on development of disease modifying ( neuroprotective ) interventions in Parkinson’s disease (PD). She is the lead investigator of a number of clinical trials on experimental pharmacology, non-motor manifestations, and pharmacological and surgical management of PD. As the Principal Investigator of the multicenter Parkinson Study Group (PSG) Phase II study of isradipine as potential disease modifying agent in early PD (STEADY PD) and more recently NET PD FS-Zone studies as well as a member of the Steering Committees on a number of national studies including PPMI, she has developed expertise in design and coordination of multicenter studies. She is actively involved with the PSG where she is an active member of three PSG working groups and Chair of the Classic Motor group. She serves on the Steering Committees for the National Parkinson Foundation.
Certifications and Licenses
Neurology |
Training Experience
1994 | Residency, Temple University Hospital |
1995 | Fellowship, Temple University Hospital |
Education/Academic qualification
MD, Medicine, Leningrad Medical School
… → 1985
Research interests keywords
- Clinical Trial Methodology
- Drug Discovery
- Movement Control
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Network
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Implementing Team-based Outpatient Palliative Care in Parkinson Foundation Centers of Excellence
7/1/22 → 6/30/23
Project: Research project
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Movement Disorders Fellowship Support 2022-2023
Boston Scientific Neuromodulation Corporation
7/1/22 → 6/30/23
Project: Research project
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The Edmond J. Safra Fellowship in Movement Disorders - Class of 2025
Simuni, T., Bega, D., Goldman, J. G., Krainc, D. & Wu, A. D.
Michael J. Fox Foundation for Parkinson's Research
4/1/22 → 6/30/25
Project: Research project
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A novel brain penetrant c-Abl tyrosine kinase inhibitor: Paving a path forward to success in disease modification in Parkinson's disease
Simuni, T. & Merchant, K., Mar 2023, In: Parkinsonism and Related Disorders. 108, 105325.Research output: Contribution to journal › Editorial › peer-review
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Enrollment of Participants from Marginalized Racial and Ethnic Groups: A Comparative Assessment of the STEADY-PD III and SURE-PD3 Trials
Di Luca, D. G., Macklin, E. A., Hodgeman, K., Lopez, G., Pothier, L., Callahan, K. F., Lowell, J., Chan, J., Videnovic, A., Lungu, C., Lang, A. E., Litvan, I., Schwarzschild, M. A. & Simuni, T., Feb 18 2023, In: Neurology: Clinical Practice. 13, 1, e200113.Research output: Contribution to journal › Article › peer-review
Open Access -
Impact of the Dopamine System on Long-Term Cognitive Impairment in Parkinson Disease: An Exploratory Study
the Parkinson’s Progression Markers Initiative, 2023, (Accepted/In press) In: Movement Disorders Clinical Practice.Research output: Contribution to journal › Article › peer-review
Open Access -
Role of novel endpoints and evaluations of response in Parkinson disease
Chahine, L. M. & Simuni, T., Jan 2023, Handbook of Clinical Neurology. Elsevier B.V., p. 325-345 21 p. (Handbook of Clinical Neurology; vol. 193).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Adjunctive Therapies in Parkinson Disease - Have We Made Meaningful Progress?
Simuni, T. & Okun, M. S., Feb 2022, In: JAMA Neurology. 79, 2, p. 119-120 2 p.Research output: Contribution to journal › Editorial › peer-review