Grants per year
Personal profile
Research Interests
Dr Simuni joined the faculty of the Northwestern University Feinberg school of Medicine in 2000 to build and lead a multidisciplinary movement disorders center that is recognized by the National Parkinson’s Foundation as a Center of Excellence and serves as a training model in the region. Her research interests are focused on development of disease modifying ( neuroprotective ) interventions in Parkinson’s disease (PD). She is the lead investigator of a number of clinical trials on experimental pharmacology, non-motor manifestations, and pharmacological and surgical management of PD. As the Principal Investigator of the multicenter Parkinson Study Group (PSG) Phase II study of isradipine as potential disease modifying agent in early PD (STEADY PD) and more recently NET PD FS-Zone studies as well as a member of the Steering Committees on a number of national studies including PPMI, she has developed expertise in design and coordination of multicenter studies. She is actively involved with the PSG where she is an active member of three PSG working groups and Chair of the Classic Motor group. She serves on the Steering Committees for the National Parkinson Foundation.
Certifications and Licenses
Neurology |
Training Experience
1994 | Residency, Temple University Hospital |
1995 | Fellowship, Temple University Hospital |
Education/Academic qualification
MD, Leningrad Medical School
… → 1985
Research interests
- Clinical Trial Methodology
- Drug Discovery
- Movement Control
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Network
Grants
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FoxBioNet: ECV (Extracellular Vesicle) 004
The Michael J Fox Foundation for Parkinson's Research
12/1/20 → 2/14/22
Project: Research project
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Trial of Parkinson's And Zoledronic Acid (TOPAZ)
Sutter Bay Hospitals, National Institute on Aging
10/14/20 → 10/13/21
Project: Research project
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Parkinson's Progression Markers Initiation (PPMI) 2.0
The Michael J Fox Foundation for Parkinson's Research
8/10/20 → 7/31/33
Project: Research project
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Research Education Program for Trainees in Neurology
National Institute of Neurological Disorders and Stroke
7/1/20 → 6/30/25
Project: Research project
Research Output
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A Predictive Model for Parkinson's Disease Reveals Candidate Gene Sets for Progression Subtype
Dennis, S. R., Simuni, T. & Luo, Y., Dec 16 2020, Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020. Park, T., Cho, Y-R., Hu, X. T., Yoo, I., Woo, H. G., Wang, J., Facelli, J., Nam, S. & Kang, M. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 417-420 4 p. 9313376. (Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study
Parkinson's Progression Markers Initiative Investigators, May 1 2020, In: Movement Disorders. 35, 5, p. 833-844 12 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study
PPMI Investigators, Jan 2020, In: The Lancet Neurology. 19, 1, p. 71-80 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Clinical and Imaging Progression in the PARS Cohort: Long-Term Follow-up
Siderowf, A., Jennings, D., Stern, M., Seibyl, J., Eberly, S., Oakes, D., Marek, K., Jennings, D., Marek, K., Seibyl, J., Siderowf, A., Stern, M., Russell, D., Sethi, K., Frank, S., Simuni, T., Hauser, R., Ravina, B., Richards, I., Liang, G. & 7 others, , Sep 1 2020, In: Movement Disorders. 35, 9, p. 1550-1557 8 p.Research output: Contribution to journal › Article › peer-review
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Clinical Trial Highlights - GLP-1 agonists
McFarthing, K., Larson, D. & Simuni, T., 2020, In: Journal of Parkinson's disease. 10, 2, p. 355-368 14 p.Research output: Contribution to journal › Article › peer-review
Open Access