Tatyana Simuni

  • Professor, Neurology
  • Arthur C. Nielsen, Jr. Research Professorship in Parkinson's Disease and Movement Disorders, Neurology
  • 9777 Citations
19982020

Research output per year

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Research Output

2020
Open Access
2 Scopus citations
5 Scopus citations

Clinical Trial Highlights - GLP-1 agonists

McFarthing, K., Larson, D. & Simuni, T., 2020, In : Journal of Parkinson's disease. 10, 2, p. 355-368 14 p.

Research output: Contribution to journalArticle

Open Access

Clinical Trial Highlights-Infusion Therapies

Prakash, N., McFarthing, K. & Simuni, T., 2020, In : Journal of Parkinson's disease. 10, 1, p. 5-17 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Correction: Genetic testing for Parkinson disease: current practice, knowledge, and attitudes among US and Canadian movement disorders specialists (Genetics in Medicine, (2019), 10.1038/s41436-019-0684-x)

Alcalay, R. N., Kehoe, C., Shorr, E., Battista, R., Hall, A., Simuni, T., Marder, K., Wills, A. M., Naito, A., Beck, J. C., Schwarzschild, M. A. & Nance, M., Feb 1 2020, In : Genetics in Medicine. 22, 2, p. 448 1 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Evolution of Alzheimer's Disease Cerebrospinal Fluid Biomarkers in Early Parkinson's Disease

Irwin, D. J., Fedler, J., Coffey, C. S., Caspell-Garcia, C., Kang, J. H., Simuni, T., Foroud, T., Toga, A. W., Tanner, C. M., Kieburtz, K., Chahine, L. M., Reimer, A., Hutten, S., Weintraub, D., Mollenhauer, B., Galasko, D. R., Siderowf, A., Marek, K., Trojanowski, J. Q. & Shaw, L. M., Sep 1 2020, In : Annals of neurology. 88, 3, p. 574-587 14 p.

Research output: Contribution to journalArticle

Open Access

Genetic testing for Parkinson disease: current practice, knowledge, and attitudes among US and Canadian movement disorders specialists

Alcalay, R. N., Kehoe, C., Shorr, E., Battista, R., Hall, A., Simuni, T., Marder, K., Wills, A. M., Naito, A., Beck, J. C., Schwarzschild, M. A. & Nance, M., Mar 1 2020, In : Genetics in Medicine. 22, 3, p. 574-580 7 p.

Research output: Contribution to journalArticle

Open Access

Infusion Therapies for Parkinson’s Disease

Prakash, N. & Simuni, T., Sep 1 2020, In : Current neurology and neuroscience reports. 20, 9, 44.

Research output: Contribution to journalReview article

Isradipine versus placebo in early Parkinson disease a randomized trial

Simuni, T., May 5 2020, In : Annals of internal medicine. 172, 9, p. 591-598 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease

Parkinson’s Progression Markers Initiative, Apr 1 2020, In : Annals of clinical and translational neurology. 7, 4, p. 449-461 13 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
1 Scopus citations

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression

Mollenhauer, B., Dakna, M., Kruse, N., Galasko, D., Foroud, T., Zetterberg, H., Schade, S., Gera, R. G., Wang, W., Gao, F., Frasier, M., Chahine, L. M., Coffey, C. S., Singleton, A. B., Simuni, T., Weintraub, D., Seibyl, J., Toga, A. W., Tanner, C. M., Kieburtz, K. & 6 others, Marek, K., Siderowf, A., Cedarbaum, J. M., Hutten, S. J., Trenkwalder, C. & Graham, D., 2020, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

Open Access
2019

Advance care planning in Parkinson’s disease: ethical challenges and future directions

Sokol, L. L., Young, M. J., Paparian, J., Kluger, B. M., Lum, H. D., Besbris, J., Kramer, N. M., Lang, A. E., Espay, A. J., Dubaz, O. M., Miyasaki, J. M., Matlock, D. D., Simuni, T. & Cerf, M., Dec 1 2019, In : npj Parkinson's Disease. 5, 1, 24.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Basic clinical features do not predict dopamine transporter binding in idiopathic REM behavior disorder

the PPMI Sleep Working Group, Dec 1 2019, In : npj Parkinson's Disease. 5, 1, 2.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Changes in Prescribing Practices of Dopaminergic Medications in Individuals with Parkinson's Disease by Expert Care Centers from 2010 to 2017: The Parkinson's Foundation Quality Improvement Initiative

the Parkinson's Foundation Quality Improvement Initiative Investigators, Nov 1 2019, In : Movement Disorders Clinical Practice. 6, 8, p. 687-692 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clinical trial highlights: Phase III study in spotlight

McFarthing, K. & Simuni, T., Jan 1 2019, In : Journal of Parkinson's disease. 9, 1, p. 3-4 2 p.

Research output: Contribution to journalComment/debate

Clinical trial highlights: Targetting alpha-synuclein

McFarthing, K. & Simuni, T., Jan 1 2019, In : Journal of Parkinson's disease. 9, 1, p. 5-16 12 p.

Research output: Contribution to journalReview article

4 Scopus citations
Open Access
3 Scopus citations

CLINICAL TRIAL HIGHLIGHTS-DYSKINESIA

McFarthing, K., Prakash, N. & Simuni, T., 2019, In : Journal of Parkinson's disease. 9, 3, p. 449-465 17 p.

Research output: Contribution to journalReview article

1 Scopus citations

Corrigendum: Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: An expert consensus (CNS Spectrums (2018) 23:6 (402-413) DOI: 10.1017/S1092852918001359)

Black, K. J., Nasrallah, H., Isaacson, S., Stacy, M., Pahwa, R., Adler, C. H., Alva, G., Cooney, J. W., Kremens, D., Menza, M. A., Meyer, J. M., Patkar, A. A., Simuni, T., Morrissette, D. A. & Stahl, S. M., Oct 1 2019, In : CNS spectrums. 24, 5, p. 574-575 2 p.

Research output: Contribution to journalComment/debate

Open Access

Daily isradipine is ineffective at slowing Parkinson’s disease

Simuni, T., Jan 1 2019, In : Clinical Pharmacist. 11, 7

Research output: Contribution to journalComment/debate

1 Scopus citations

Development and validation of the automated imaging differentiation in parkinsonism (AID-P): a multicentre machine learning study

Archer, D. B., Bricker, J. T., Chu, W. T., Burciu, R. G., McCracken, J. L., Lai, S., Coombes, S. A., Fang, R., Barmpoutis, A., Corcos, D. M., Kurani, A. S., Mitchell, T., Black, M. L., Herschel, E., Simuni, T., Parrish, T. B., Comella, C., Xie, T., Seppi, K., Bohnen, N. I. & 11 others, Müller, M. LTM., Albin, R. L., Krismer, F., Du, G., Lewis, M. M., Huang, X., Li, H., Pasternak, O., McFarland, N. R., Okun, M. S. & Vaillancourt, D. E., Sep 2019, In : The Lancet Digital Health. 1, 5, p. e222-e231

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Feasibility and safety of lumbar puncture in the Parkinson's disease research participants: Parkinson's Progression Marker Initiative (PPMI)

The Parkinson's Progression Markers InitiativeSteering Committee, Study Cores, Site Investigators, Coordinators & Industry and Scientific Advisory Board, May 2019, In : Parkinsonism and Related Disorders. 62, p. 201-209 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease

for the PPMI study, Sep 1 2019, In : Movement Disorders. 34, 9, p. 1354-1364 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Neurite orientation dispersion and density imaging (NODDI) and free-water imaging in Parkinsonism

Mitchell, T., Archer, D. B., Chu, W. T., Coombes, S. A., Lai, S., Wilkes, B. J., McFarland, N. R., Okun, M. S., Black, M. L., Herschel, E., Simuni, T., Comella, C., Xie, T., Li, H., Parrish, T. B., Kurani, A. S., Corcos, D. M. & Vaillancourt, D. E., Dec 1 2019, In : Human Brain Mapping. 40, 17, p. 5094-5107 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

New Era in disease modification in Parkinson's disease: Review of genetically targeted therapeutics

Sardi, S. P. & Simuni, T., Feb 2019, In : Parkinsonism and Related Disorders. 59, p. 32-38 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Predicting Progression in Parkinson's Disease Using Baseline and 1-Year Change Measures

Chahine, L. M., Siderowf, A., Barnes, J., Seedorff, N., Caspell-Garcia, C., Simuni, T., Coffey, C. S., Galasko, D., Mollenhauer, B., Arnedo, V., Daegele, N., Frasier, M., Tanner, C., Kieburtz, K. & Marek, K., 2019, In : Journal of Parkinson's disease. 9, 4, p. 665-679 15 p.

Research output: Contribution to journalArticle

Open Access

Self-reported physical activity levels and clinical progression in early Parkinson's disease

the Parkinson's Progression Markers Initiative, Apr 2019, In : Parkinsonism and Related Disorders. 61, p. 118-125 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Using Implementation Frameworks to Provide Proactive Physical Therapy for People With Parkinson Disease: Case Report

Rafferty, M. R., MacDonald, J., Byskosh, A., Sloan, L., Toledo, S., Marciniak, C. & Simuni, T., Dec 16 2019, In : Physical therapy. 99, 12, p. 1644-1655 12 p.

Research output: Contribution to journalArticle

2018
4 Scopus citations

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson's disease: The PPMI cohort

Simuni, T., Caspell-Garcia, C., Coffey, C. S., Weintraub, D., Mollenhauer, B., Lasch, S., Tanner, C. M., Jennings, D., Kieburtz, K., Chahine, L. M. & Marek, K., Jan 1 2018, In : Journal of Neurology, Neurosurgery and Psychiatry. 89, 1, p. 78-88 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Cognition among individuals along a spectrum of increased risk for Parkinson’s disease

the Parkinson’s Progression Markers Initiative, Aug 2018, In : PloS one. 13, 8, e0201964.

Research output: Contribution to journalArticle

7 Scopus citations

Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: An expert consensus

Black, K. J., Nasrallah, H., Isaacson, S., Stacy, M., Pahwa, R., Adler, C. H., Alva, G., Cooney, J. W., Kremens, D., Menza, M. A., Meyer, J. M., Patkar, A. A., Simuni, T., Morrissette, D. A. & Stahl, S. M., Dec 1 2018, In : CNS spectrums. 23, 6, p. 402-413 12 p.

Research output: Contribution to journalArticle

High priority publications on Parkinson's disease in 2017

Simuni, T. & Krainc, D., Jan 2018, In : The Lancet Neurology. 17, 1, p. 8-10 3 p.

Research output: Contribution to journalComment/debate

Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort

the Parkinson's Progression Marker Initiative*, May 2018, In : Movement Disorders. 33, 5, p. 771-782 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Predictors of clinically meaningful change in PDQ-39 in Parkinson's disease

the NPF QII Investigators, Nov 2018, In : Parkinsonism and Related Disorders. 56, p. 93-97 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort

the Parkinson's Progression Markers Initiative, Dec 2018, In : Annals of clinical and translational neurology. 5, 12, p. 1460-1477 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

The spectrum of “off” in Parkinson's disease: What have we learned over 40 years?

Chou, K. L., Stacy, M., Simuni, T., Miyasaki, J., Oertel, W. H., Sethi, K., Fernandez, H. H. & Stocchi, F., Jun 1 2018, In : Parkinsonism and Related Disorders. 51, p. 9-16 8 p.

Research output: Contribution to journalReview article

21 Scopus citations

Wearable sensors for Parkinson’s disease: which data are worth collecting for training symptom detection models

Lonini, L., Dai, A., Shawen, N., Simuni, T., Poon, C., Shimanovich, L., Daeschler, M., Ghaffari, R., Rogers, J. A. & Jayaraman, A., Dec 1 2018, In : npj Digital Medicine. 1, 1, 64.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2017

Altered premotor cortical oscillations during repetitive movement in persons with Parkinson's disease

Stegemöller, E. L., Allen, D. P., Simuni, T. & MacKinnon, C. D., Jan 15 2017, In : Behavioural Brain Research. 317, p. 141-146 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Calcium, mitochondrial dysfunction and slowing the progression of Parkinson's disease

Surmeier, D. J., Halliday, G. M. & Simuni, T., Dec 2017, In : Experimental Neurology. 298, p. 202-209 8 p.

Research output: Contribution to journalReview article

41 Scopus citations

Can loss of the swallow tail sign help distinguish between Parkinson Disease and the Parkinson-Plus syndromes?

Oustwani, C. S., Korutz, A. W., Lester, M. S., Kianirad, Y., Simuni, T. & Hijaz, T. A., Jul 1 2017, In : Clinical Imaging. 44, p. 66-69 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Erratum to: Inaugural Conference on Incorporating Patient-Reported Outcomes and Patient Preference Information into Clinical Research, Clinical Care, and Risk-Benefit Assessments for Neurodegenerative Diseases (The Patient - Patient-Centered Outcomes Research, (2017), 10, 5, (541-544), 10.1007/s40271-017-0257-5)

Purks, J. L., Wilhelm, E. E., Shoulson, I., Creveling, J., Dorsey, E. R., Irony, T., LoCastro, T. M., Pagan, F., Ravina, B., Simuni, T., Sterling, M. A., Tariot, P. & Anderson, K. E., Oct 1 2017, In : Patient. 10, 5, p. 667-668 2 p.

Research output: Contribution to journalComment/debate

Inaugural Conference on Incorporating Patient-Reported Outcomes and Patient Preference Information into Clinical Research, Clinical Care, and Risk-Benefit Assessments for Neurodegenerative Diseases

Purks, J. L., Wilhelm, E. E., Shoulson, I., Creveling, J., Dorsey, E. R., Irony, T., LoCastro, T. M., Pagan, F., Ravina, B., Simuni, T., Sterling, M. A., Tariot, P. & Anderson, K. E., Oct 1 2017, In : Patient. 10, 5, p. 541-544 4 p.

Research output: Contribution to journalLetter

5 Scopus citations

Increasing Efficiency of Recruitment in Early Parkinson's Disease Trials: A Case Study Examination of the STEADY-PD III Trial

Berk, S., Greco, B. L., Biglan, K., Kopil, C. M., Holloway, R. G., Meunier, C. & Simuni, T., 2017, In : Journal of Parkinson's disease. 7, 4, p. 685-693 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Laughter is the best medicine: The Second City® improvisation as an intervention for Parkinson's disease

Bega, D., Palmentera, P., Wagner, A., Hovde, M., Barish, B., Kwasny, M. J. & Simuni, T., Jan 1 2017, In : Parkinsonism and Related Disorders. 34, p. 62-65 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Longitudinal assessment of excessive daytime sleepiness in early Parkinson's disease

Parkinson's Progression Markers Initiative, Aug 1 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 8, p. 653-662 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
8 Scopus citations

Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease

Caspell-Garcia, C., Simuni, T., Tosun-Turgut, D., Wu, I. W., Zhang, Y., Nalls, M., Singleton, A., Shaw, L. A., Kang, J. H., Trojanowski, J. Q., Siderowf, A., Coffey, C., Lasch, S., Aarsland, D., Burn, D., Chahine, L. M., Espay, A. J., Foster, E. D., Hawkins, K. A., Litvan, I. & 2 others, Richard, I. & Weintraub, D., May 2017, In : PloS one. 12, 5, e0175674.

Research output: Contribution to journalArticle

55 Scopus citations

Pimavanserin, a novel antipsychotic for management of Parkinson’s disease psychosis

Kianirad, Y. & Simuni, T., Nov 2 2017, In : Expert Review of Clinical Pharmacology. 10, 11, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

5 Scopus citations