• Source: Scopus
1983 …2021

Research activity per year

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Personal profile

Research Interests

My interest is in understanding mechanism of disease. Our approach is gene discovery, animal and cell culture modeling and therapeutic application in disorders of the nervous system. My specific emphasis is on neurodegenerative conditions and those affecting the neuromuscular system. We have focused on amyotrophic lateral sclerosis, the spastic paraparesis, primary lateral sclerosis and frontal-temporal lobe dementias as protoptypic neurodegenerative disorders. We have identified several genes that cause these disorders and have made animal models to study their pathogenesis. In addition I collabotate with colleagues in the study of mitochondrial disorder of muscle and the peripheral neuropathies.

Certifications and Licenses

Neurology

Training Experience

1976Internship, Perth Amboy General Hospital
1979Residency, UMDNJ-University Hospital
1980Fellowship, Hospital for Special Surgery
1981Fellowship, National Institutes of Health

Education/Academic qualification

Medicine, MD, Dow Medical College, Pakistan

… → 1973

Research interests

  • ALS
  • Dementia
  • Drug Discovery
  • Genomic Medicine/Personalized Medicine
  • Molecular Diagnostics
  • Molecular Genetics
  • Neuromuscular Disorders
  • Neuroscience

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