Grants per year
Personal profile
Education/Academic qualification
Biopharmaceutial Sciences, PhD, University of Illinois at Chicago
… → 2016
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Collaborations and top research areas from the last five years
Grants
- 1 Active
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Elucidating the mechanism of Ga13 mediated tumor suppression in pancreatic cancer
Shields, M. (PD/PI), Mi, X. (Co-Investigator) & Pham, T. N. D. (Co-Investigator)
8/1/23 → 7/31/28
Project: Research project
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Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer
Principe, D. R., Aissa, A. F., Kumar, S., Pham, T. N. D., Underwood, P. W., Nair, R., Ke, R., Rana, B., Trevino, J. G., Munshi, H. G., Benevolenskaya, E. V. & Rana, A., May 3 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 18, e2200143119.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
Shields, M. A., Spaulding, C., Metropulos, A. E., Khalafalla, M. G., Pham, T. N. D. & Munshi, H. G., Mar 1 2022, In: Cell reports. 38, 9, 110441.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Inhibiting MNKs promote macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity
Pham, T. N. D., Spaulding, C., Shields, M. A., Metropulos, A. E., Shah, D. N., Khalafalla, M. G., Principe, D. R., Bentrem, D. J. & Munshi, H. G., May 9 2022, In: JCI Insight. 7, 9, e152731.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer
Principe, D. R., Xiong, R., Li, Y., Pham, T. N. D., Kamath, S. D., Dubrovskyi, O., Ratia, K., Huang, F., Zhao, J., Shen, Z., Thummuri, D., Daohong, Z., Underwood, P. W., Trevino, J., Munshi, H. G., Thatcher, G. R. J. & Rana, A., Jan 25 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 4, e2116764119.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Preclinical models of pancreatic ductal adenocarcinoma and their utility in immunotherapy studies
Pham, T. N. D., Shields, M. A., Spaulding, C., Principe, D. R., Li, B., Underwood, P. W., Trevino, J. G., Bentrem, D. J. & Munshi, H. G., 2021, In: Cancers. 13, 3, p. 1-22 22 p., 440.Research output: Contribution to journal › Review article › peer-review
Open Access26 Scopus citations
Datasets
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CBP bromodomain complexed with YF2-23
Principe, D. R. (Contributor), Xiong, R. (Contributor), Li, Y. (Contributor), Pham, T. N. D. (Contributor), Kamath, S. D. (Contributor), Dubrovskyi, O. (Contributor), Ratia, K. (Contributor), Huang, F. (Contributor), Zhao, J. (Contributor), Shen, Z. (Contributor), Thummuri, D. (Contributor), Daohong, Z. (Contributor), Underwood, P. W. (Contributor), Trevino, J. (Contributor), Munshi, H. G. (Contributor), Thatcher, G. R. J. (Contributor), Rana, A. (Contributor), Gutgesell, L. M. (Contributor), Dye, K. (Contributor), Zhao, H. (Contributor) & Tonetti, D. A. (Contributor), Protein Data Bank (PDB), Sep 1 2021
DOI: 10.2210/pdb7JUO, https://www.wwpdb.org/pdb?id=pdb_00007juo
Dataset
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Quercetin enhances the anti-tumor effects of BET inhibitors Supplementary Figures
Pham, T. (Contributor), ZENODO, Jul 10 2019
DOI: 10.5281/zenodo.3284893, https://zenodo.org/record/3284893
Dataset