Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biopharmaceutial Sciences, PhD, University of Illinois at Chicago
… → 2016
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Collaborations and top research areas from the last five years
Grants
- 1 Finished
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Elucidating the mechanism of Ga13 mediated tumor suppression in pancreatic cancer
Shields, M. (PD/PI), Mi, X. (Co-Investigator) & Pham, T. N. D. (Co-Investigator)
8/1/23 → 7/1/24
Project: Research project
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BET Inhibition Rescues Acinar-Ductal-Metaplasia and Ciliogenesis and Ameliorates Chronic Pancreatitis-Driven Changes in Mice with Loss of the Polarity Protein Par3
Shields, M. A., Metropulos, A. E., Spaulding, C., Alzahrani, K. A., Hirose, T., Ohno, S., Pham, T. N. D. & Munshi, H. G., Jan 2024, In: CMGH. 18, 5, 101389.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12DInhibitor MRTX1133 in Pancreatic Cancer
Becker, J. H., Metropulos, A. E., Spaulding, C., Marinelarena, A. M., Shields, M. A., Principe, D. R., Pham, T. D. & Munshi, H. G., Nov 2024, In: Cancer Research. 84, 21, p. 3629-3639 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer
Principe, D. R., Aissa, A. F., Kumar, S., Pham, T. N. D., Underwood, P. W., Nair, R., Ke, R., Rana, B., Trevino, J. G., Munshi, H. G., Benevolenskaya, E. V. & Rana, A., May 3 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 18, e2200143119.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
Shields, M. A., Spaulding, C., Metropulos, A. E., Khalafalla, M. G., Pham, T. N. D. & Munshi, H. G., Mar 1 2022, In: Cell reports. 38, 9, 110441.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Inhibiting MNKs promote macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity
Pham, T. N. D., Spaulding, C., Shields, M. A., Metropulos, A. E., Shah, D. N., Khalafalla, M. G., Principe, D. R., Bentrem, D. J. & Munshi, H. G., May 9 2022, In: JCI Insight. 7, 9, e152731.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations
Datasets
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CBP bromodomain complexed with YF2-23
Li, Y. (Contributor), Zhao, J. (Contributor), Gutgesell, L. M. (Contributor), Shen, Z. (Contributor), Ratia, K. (Contributor), Dye, K. (Contributor), Dubrovskyi, O. (Contributor), Zhao, H. (Contributor), Huang, F. (Contributor), Tonetti, D. A. (Contributor), Thatcher, G. R. J. (Contributor), Xiong, R. (Contributor), Principe, D. R. (Contributor), Pham, T. N. D. (Contributor), Kamath, S. D. (Contributor), Thummuri, D. (Contributor), Daohong, Z. (Contributor), Underwood, P. W. (Contributor), Trevino, J. (Contributor), Munshi, H. G. (Contributor) & Rana, A. (Contributor), Protein Data Bank (PDB), Sep 1 2021
DOI: 10.2210/pdb7JUO/pdb, https://www.wwpdb.org/pdb?id=pdb_00007juo
Dataset
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Quercetin enhances the anti-tumor effects of BET inhibitors Supplementary Figures
Pham, T. (Contributor), ZENODO, Jul 10 2019
DOI: 10.5281/zenodo.3284893, https://zenodo.org/record/3284893
Dataset