Grants per year
Personal profile
Research Interests
I received my PhD in immunology from the University of Chicago where I discovered the function of CTLA-4, the first checkpoint inhibitor. Following my MS in computer science, I worked in microbial genomics developing informatics tools to understand biochemical pathways in microorganisms. I joined the Nortwestern faculty to focus on medical informatics and am Associate Director for the Center for Health Information Partnerships and Director of the Chicago Health IT Regional Extension Center.
My goal is to improve health for people with autoimmune disease, using immunological, genomics, informatics and implementation science methods to study the development of autoimmunity. My research focuses on using electronic health records, intersected with genetic, social and environmental data to 1) develop translational models to elucidate the molecular and environmental mechanisms of human autoimmune disease and 2) develop EHR-based tools to improve care for people with autoimmunity.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MS, Computer Science, DePaul University
… → 2004
Immunology, PhD, University of Chicago
… → 1997
Research interests keywords
- Autoimmune Diseases
- Big Data
- Bioinformatics
- Genomic Medicine/Personalized Medicine
- Healthcare Quality
- Immunology
- Implementation Science
- Medical Informatics
- Systemic Lupus Erythematosus
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Transforming health at the intersection of implementation science, learning health systems, and genomics at Northwestern Medicine
Beidas, R. S. (PD/PI), Franklin, P. D. (PD/PI), Godley, L. A. (PD/PI), McNally, E. M. (PD/PI), Ahmad, F. S. (Co-Investigator), Bass, M. (Co-Investigator), Beach, L. B. (Co-Investigator), Becker, S. (Co-Investigator), Bradley, C. D. (Co-Investigator), Chisholm, R. L. (Co-Investigator), Chorniy, A. (Co-Investigator), Holmes, K. (Co-Investigator), Rasmussen-Torvik, L. J. (Co-Investigator), Rini, C. (Co-Investigator), Scott, K. (Co-Investigator), Skolarus, L. E. (Co-Investigator), Walunas, T. L. (Co-Investigator) & Young, J. L. (Co-Investigator)
National Human Genome Research Institute
9/1/24 → 12/31/24
Project: Research project
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Element B + Subcontracts
Becker, S. (PD/PI), D'Aquila, R. T. (PD/PI), Yancy, C. W. (PD/PI), Alshurafa, N. (Other), Ameer, G. A. (Other), Beidas, R. S. (Other), Blanco, I. (Other), Bradley, C. D. (Other), Brawley, C. (Other), Brown, O. E. (Other), Brown, C. H. (Other), Cameron, K. A. (Other), Carnethon, M. R. (Other), Cooper, L. A. D. (Other), Feinstein, M. J. (Other), Franklin, P. D. (Other), Helseth, S. A. (Other), Hill, V. B. (Other), Holmes, K. (Other), Kalhan, R. (Other), Khan, S. S. (Other), Kho, A. N. (Other), Li, D. H. (Other), Liebovitz, D. M. (Other), Luo, Y. (Other), Macapagal, K. (Other), O'Brien, M. J. (Other), Passman, R. S. (Other), Perreault, E. (Other), Peters, A. T. (Other), Pickens, C. I. (Other), Rasmussen-Torvik, L. J. (Other), Rivnay, J. (Other), Rosenberg, S. R. (Other), Schauer, J. M. (Other), Scott, K. (Other), Scott, E. A. (Other), Simon, M. A. (Other), Skolarus, L. E. (Other), Spring, B. (Other), Starren, J. (Other), Tandon, D. (Other), Walunas, T. L. (Other), Welty, L. J. (Other), Woitowich, N. C. (Other) & Wolf, M. (Other)
National Center for Advancing Translational Sciences
9/1/24 → 7/31/31
Project: Research project
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The Neu-Lung Consortium: Neutrophilic Mechanisms of Inflammation, Injury, and Repair in Lung and Airways Diseases
Fourati, S. (Co-Investigator), Luo, Y. (Co-Investigator), Morales-Nebreda, L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Wunderink, R. G. (Co-Investigator) & Walunas, T. L. (Other)
National Institute of Allergy and Infectious Diseases
4/1/24 → 3/31/29
Project: Research project
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Dynamic Inflammatory Determinants of Heart Failure with Preserved Ejection Fraction
Feinstein, M. J. (PD/PI), Carnethon, M. R. (Co-Investigator), Fourati, S. (Co-Investigator), Lloyd-Jones, D. M. (Co-Investigator) & Walunas, T. L. (Co-Investigator)
4/1/24 → 3/31/28
Project: Research project
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Machine learning to predict cure in severe pneumonia episodes
Gao, C. A. (PD/PI), Andrei, A.-C. (Other), Budinger, G. S. (Other), Luo, Y. (Other), Misharin, A. (Other), Singer, B. (Other), Starren, J. (Other), Walunas, T. L. (Other) & Wunderink, R. G. (Other)
National Heart, Lung, and Blood Institute
4/1/24 → 3/31/29
Project: Research project
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Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma
Rabin, E. E., Huang, J., Kim, M., Mozny, A., Lauing, K. L., Penco-Campillo, M., Zhai, L., Bommi, P., Mi, X., Power, E. A., Prabhu, V. C., Anderson, D. E., Barton, K. P., Walunas, T. L., Schiltz, G. E., Amidei, C., Sanchez-Gomez, P., Thakkar, J. P., Lukas, R. V. & Wainwright, D. A., Jul 2024, In: Brain, Behavior, and Immunity - Health. 38, 100753.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinical associations with a polygenic predisposition to benign lower white blood cell counts
Mosley, J. D., Shelley, J. P., Dickson, A. L., Zanussi, J., Daniel, L. L., Zheng, N. S., Bastarache, L., Wei, W. Q., Shi, M., Jarvik, G. P., Rosenthal, E. A., Khan, A., Sherafati, A., Kullo, I. J., Walunas, T. L., Glessner, J., Hakonarson, H., Cox, N. J., Roden, D. M. & Frangakis, S. G. & 8 others, , Dec 2024, In: Nature communications. 15, 1, 3384.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic sex validation for sample tracking in next-generation sequencing clinical testing
the eMERGE III consortium, Dec 2024, In: BMC Research Notes. 17, 1, 62.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Interventions and contextual factors to improve retention in care for patients with hypertension in primary care: Hermeneutic systematic review
Ye, J., Sanuade, O. A., Hirschhorn, L. R., Walunas, T. L., Smith, J. D., Birkett, M. A., Baldridge, A. S., Ojji, D. B. & Huffman, M. D., Mar 2024, In: Preventive medicine. 180, 107880.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Multiplicative Impact of Adverse Social Determinants of Health on Outcomes in Lupus Nephritis: A Meta-analysis and Systematic Review
Garg, S., Sweet, N., Boderman, B., Montes, D., Walunas, T., Ramsey-Goldman, R., Khosroshahi, A., Astor, B. C., Lim, S. S. & Bartels, C. M., Sep 2024, In: Arthritis Care and Research. 76, 9, p. 1232-1245 14 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Electronic health record data use in the assessment of quality indicators for glucocorticoid osteoporosis screening in systemic lupus erythematosus
Ko, D. (Creator), Forrest, N. (Creator), Mai, Q. (Creator), Pawlowski, A. (Creator), Balsley, K. (Creator), Chung, A. (Creator), Ramsey-Goldman, R. (Creator) & Walunas, T. L. (Creator), SAGE Journals, 2022
DOI: 10.25384/sage.c.6235403, https://sage.figshare.com/collections/Electronic_health_record_data_use_in_the_assessment_of_quality_indicators_for_glucocorticoid_osteoporosis_screening_in_systemic_lupus_erythematosus/6235403
Dataset
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sj-xlsx-1-lup-10.1177_09612033211014952 - Supplemental material for Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis
Kawai, V. K. (Creator), Shi, M. (Contributor), Liu, G. (Creator), Feng, Q. (Creator), Wei, W. (Creator), Chung, C. P. (Creator), Walunas, T. L. (Creator), Gordon, A. S. (Creator), Linneman, J. G. (Creator), Hebbring, S. J. (Creator), Harley, J. B. (Creator), Cox, N. J. (Creator), Roden, D. M. (Creator), Stein, C. M. (Contributor) & Mosley, J. D. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.14588139, https://sage.figshare.com/articles/dataset/sj-xlsx-1-lup-10_1177_09612033211014952_-_Supplemental_material_for_Pleiotropy_of_systemic_lupus_erythematosus_risk_alleles_and_cardiometabolic_disorders_A_phenome-wide_association_study_and_inverse-variance_weighted_meta-analysis/14588139
Dataset
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A metadata framework for electronic phenotypes
Spotnitz, M. (Contributor), Acharya, N. (Contributor), Cimino, J. J. (Contributor), Murphy, S. (Contributor), Namjou-Khales, B. (Contributor), Crimmins, N. (Contributor), Walunas, T. (Contributor), Liu, C. (Contributor), Crosslin, D. (Contributor), Benoit, B. (Contributor), Rosenthal, E. (Contributor), Pacheco, J. (Contributor), Ostropolets, A. (Contributor), Reyes Nieva, H. (Contributor), Patterson, J. (Contributor), Richter, L. (Contributor), Callahan, T. (Contributor), Elhussein, A. (Contributor), Pang, C. (Contributor), Kiryluk, K. (Contributor), Nestor, J. (Contributor), Mohan, S. (Contributor), Minty, E. (Contributor), Wei, W.-Q. (Contributor), Natarajan, K. (Contributor) & Weng, C. (Contributor), ZENODO, May 1 2023
DOI: 10.5061/dryad.rn8pk0ph3, https://zenodo.org/record/7883685
Dataset
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Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis
Kawai, V. K. (Creator), Shi, M. (Contributor), Liu, G. (Creator), Feng, Q. (Creator), Wei, W. (Creator), Chung, C. P. (Creator), Walunas, T. L. (Creator), Gordon, A. S. (Creator), Linneman, J. G. (Creator), Hebbring, S. J. (Creator), Harley, J. B. (Creator), Cox, N. J. (Creator), Roden, D. M. (Creator), Stein, C. M. (Contributor) & Mosley, J. D. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.c.5423292, https://sage.figshare.com/collections/Pleiotropy_of_systemic_lupus_erythematosus_risk_alleles_and_cardiometabolic_disorders_A_phenome-wide_association_study_and_inverse-variance_weighted_meta-analysis/5423292
Dataset
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A metadata framework for electronic phenotypes
Spotnitz, M. (Creator), Acharya, N. (Creator), Cimino, J. J. (Creator), Murphy, S. (Creator), Namjou-Khales, B. (Creator), Crimmins, N. (Creator), Walunas, T. (Creator), Liu, C. (Creator), Crosslin, D. (Creator), Benoit, B. (Creator), Rosenthal, E. (Creator), Pacheco, J. (Creator), Ostropolets, A. (Creator), Reyes Nieva, H. (Creator), Patterson, J. (Creator), Richter, L. (Creator), Callahan, T. (Creator), Elhussein, A. (Creator), Pang, C. (Creator), Kiryluk, K. (Creator), Nestor, J. (Creator), Mohan, S. (Creator), Minty, E. (Creator), Wei, W.-Q. (Creator), Natarajan, K. (Creator) & Weng, C. (Creator), Dryad, May 1 2023
DOI: 10.5061/dryad.rn8pk0ph3, https://datadryad.org/stash/dataset/doi:10.5061/dryad.rn8pk0ph3
Dataset