Thomas J Hope

Grants

Grants per year 2005 2011 2015 2017 2020 2027

• 1 Not started
• 21 Active
• 89 Finished

Grants per year

Search results

• Finished

  Task B08 Option 3c for "Development and Use of a Non-Human Primate Model of SARS-CoV-2 Infection."

  Hope, T. J.

  Tulane University, National Institute of Allergy and Infectious Diseases

  5/22/20 → 5/31/21

  Project: Research project

  • Imaging techniques 100%
  • Microbiology 99%
  • Vaccines 89%
  • Antibodies 83%
  • Animals 63%

• Task B08 Option 3d for "Development and Use of a Non-Human Primate Model of SARS-CoV-2 Infection."

  Hope, T. J.

  Tulane University, National Institute of Allergy and Infectious Diseases

  5/22/20 → 5/31/21

  Project: Research project

  • antibodies 100%
  • microscopy 92%
  • animal models 88%
  • infection 53%
  • chelating agents 53%

• Bridging Antibody Fc-mediated Antiviral Functions Across Humans and Nonhuman Primates

  Hope, T. J.

  Duke University, National Institute of Allergy and Infectious Diseases

  5/1/20 → 4/30/22

  Project: Research project

  • Primates 100%
  • antibodies 84%
  • tissues 49%
  • ships 42%
  • Macaca 41%

• The role of steady state broadly neutralizing antibody tissue levels in preventing distal site SHIV replication

  Hope, T. J.

  Rush University Medical Center, Office of the Director, National Institutes of Health

  10/1/19 → 3/25/22

  Project: Research project

  • Broadly Neutralizing Antibodies 100%
  • RNA 49%
  • DNA 39%
  • Proteins 26%

• 5-laser 30-parameter FACSymphony-S6 SORP Cell Sorter from BD Biosciences

  Perlman, H. R., Abecassis, M. M., Bharat, A., Budinger, G. S., D'Aquila, R. T., Hope, T. J., Kato, A., Le Poole, I. C., Lesniak, M. S., Luo, X., Misharin, A., Schleimer, R. P., Singer, B., Swaminathan, S., Sznajder, J. I., Tetreault, M., Thorp, E. B. & Wunderink, R. G.

  Office of the Director, National Institutes of Health

  8/8/19 → 8/7/20

  Project: Research project

  • Sorting 100%
  • Lasers 58%
  • Cells 49%
  • Fusion reactions 41%
  • Health 37%

• 2019 CFAR Women and HIV Symposium

  Hope, T. J.

  National Institute of Allergy and Infectious Diseases

  7/22/19 → 6/30/20

  Project: Research project

  • networking 100%
  • mentoring 84%
  • poster 49%
  • grant 38%
  • minority 31%

• 2nd Annual HIV Mucosal Systems Meeting

  Hope, T. J.

  Gilead Sciences, Inc.

  5/5/19 → 7/31/19

  Project: Research project

  • HIV 100%
  • Pre-Exposure Prophylaxis 75%
  • HIV Infections 47%
  • Broadly Neutralizing Antibodies 37%
  • Financial Management 30%

• Using 3-D Primary Mucosal Cultures to Study Antibody Function at Mucosal Barrier

  Hope, T. J.

  Fred Hutchinson Cancer Research Center, National Institute of Allergy and Infectious Diseases

  11/1/18 → 11/30/19

  Project: Research project

  • Antibodies 100%
  • HIV 91%
  • Viruses 66%
  • Vaccines 49%
  • Broadly Neutralizing Antibodies 46%

• Mucosal mechanisms of altered HIV susceptibility in adolescents

  Hope, T. J.

  University of Miami, National Institute of Allergy and Infectious Diseases

  5/1/18 → 12/31/20

  Project: Research project

  • Cell Count 100%
  • HIV 92%
  • Biopsy 81%
  • Phenotype 80%
  • Infections 63%

• Molecular characterization of interferon-resistant HIV-1 using novel imaging techniques

  Hope, T. J.

  U.S. Civilian Research & Development Foundation, Department of Agriculture

  4/20/17 → 3/31/18

  Project: Research project

  • HIV-1 100%
  • Interferons 73%
  • Interferon-beta 53%
  • Kinetics 33%
  • HIV Infections 32%

• Innate Immune Surveillance of HIV-1 During Transmission and Systemic Infection

  Hope, T. J.

  Sanford Burnham Prebys Medical Discovery Institute, National Institute of Allergy and Infectious Diseases

  2/28/17 → 10/31/21

  Project: Research project

  • Infectious Disease Transmission 100%
  • HIV-1 72%
  • Capsid 64%
  • RNA Sequence Analysis 62%
  • HIV Infections 49%

• Mucosal mechanisms of altered HIV susceptibility in adolescents

  Hope, T. J.

  University of Washington, National Institute of Allergy and Infectious Diseases

  1/17/17 → 4/30/18

  Project: Research project

  • Primates 100%
  • Cell Count 80%
  • HIV 73%
  • Biopsy 65%
  • Phenotype 64%

• Comparing HIV Mucosal Targets in US and Kenyan Populations

  Hope, T. J.

  International AIDS Vaccine Initiative, Agency for International Development

  1/1/17 → 12/31/21

  Project: Research project

  • Viruses 100%
  • HIV 90%
  • Microscopy 62%
  • Population 51%
  • Kenya 43%

• Immune response and efficacy of a novel SIV-based vaccine displaying native, functional envelope trimers in female rhesus macaques

  Hope, T. J.

  Office of the Director, National Institutes of Health

  9/1/16 → 9/22/16

  Project: Research project

  • SAIDS Vaccines 100%
  • Vaccines 70%
  • Macaca mulatta 65%
  • Research Personnel 43%
  • HIV 42%

• Virus Imaging Core P50 GM082545 CHEETAH

  Hope, T. J.

  University of Utah, National Institute of General Medical Sciences

  8/1/16 → 7/31/17

  Project: Research project

• Defense-in-depth against mucosal HIV clade C invasion

  Hope, T. J.

  Texas Biomedical Research Institute, National Institute of Allergy and Infectious Diseases

  7/13/16 → 9/15/19

  Project: Research project

  • viruses 100%
  • microscopy 93%
  • antibodies 67%
  • Macaca mulatta 51%
  • mucosa 49%

• HIV Research for Prevention 2016: Vaccine, Microbicide and ARV-based Prevention Science (HIV R4P)

  Hope, T. J.

  National Institute of Allergy and Infectious Diseases

  7/1/16 → 6/30/18

  Project: Research project

  • HIV 100%
  • Anti-Infective Agents 90%
  • Congresses 77%
  • Vaccines 69%
  • Pre-Exposure Prophylaxis 31%

• Binding Antibody FcMediated Antiviral Functions Across Humans and Non-human Primates

  Hope, T. J.

  Duke University, National Institute of Allergy and Infectious Diseases

  5/1/16 → 4/30/21

  Project: Research project

  • Viruses 100%
  • Primates 93%
  • Antiviral Agents 85%
  • Antibodies 69%
  • Program Evaluation 56%

• Drug at the Right Place and Concentration: Optimizing Sustained PreP Agents

  Hope, T. J.

  Albert Einstein College of Medicine, Inc., National Institute of Allergy and Infectious Diseases

  1/1/16 → 12/31/18

  Project: Research project

• Viral Infection Bottleneck - Mucosal Pilot Study

  Hope, T. J.

  International AIDS Vaccine Initiative, Agency for International Development

  9/23/15 → 6/30/16

  Project: Research project

  • Luciferases 100%
  • Virus Diseases 78%
  • Viruses 71%
  • Biopsy 64%

• Identifying the Earliest Immune Responses to HIV Infection in Women

  Hope, T. J.

  Northwestern Memorial Hospital

  9/1/15 → 8/31/19

  Project: Research project

  • HIV Infections 100%
  • Virus Diseases 83%
  • Immune System 59%
  • Reproductive Tract Infections 53%
  • Heterosexuality 43%

• Admin Supplement

  Hope, T. J.

  National Institute of Allergy and Infectious Diseases

  7/7/15 → 6/30/21

  Project: Research project

  • Drug Delivery Systems 100%
  • HIV 93%
  • Pharmaceutical Preparations 63%
  • Lead 61%
  • Investigational New Drug Application 58%

• SRS-1 Core & SRS-2 Core: subcontracts to Utah and PSI

  Hope, T. J.

  National Institute of Allergy and Infectious Diseases

  7/7/15 → 6/30/21

  Project: Research project

  • Drug Delivery Systems 100%
  • HIV 93%
  • Pharmaceutical Preparations 63%
  • Lead 61%
  • Investigational New Drug Application 58%

• SRS-3 Core

  Kiser, P. & Hope, T. J.

  National Institute of Allergy and Infectious Diseases

  7/7/15 → 6/30/21

  Project: Research project

  • Drug Delivery Systems 100%
  • HIV 93%
  • Pharmaceutical Preparations 63%
  • Lead 61%
  • Investigational New Drug Application 58%

• IND-ES Core: subcontract to EVMS

  Hope, T. J.

  National Institute of Allergy and Infectious Diseases

  7/7/15 → 6/30/21

  Project: Research project

  • Investigational New Drug Application 100%
  • Drug Delivery Systems 57%
  • HIV 53%
  • Pharmaceutical Preparations 36%
  • Lead 35%