Grants per year
Personal profile
Research Interests
Professor Meade Lab's research focuses on inorganic coordination chemistry for the study of molecular imaging of in vivo gene expression and intracellular messengers, transition metal enzyme inhibitors, and electronic biosensors. The design, synthesis and physical properties of transition metal and lanthanide coordination complexes are the foundation of its research.
Education/Academic qualification
PhD, Ohio State University
… → 1985
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Collaborations and top research areas from the last five years
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MR Imaging of Bioscaffold-Induced Neural Progenitor Migration
University of Pittsburgh, National Institute of Neurological Disorders and Stroke
7/1/21 → 6/30/24
Project: Research project
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PSMA-targeted AuNPs for MR guided radiotherapy and radiosensitization
Case Western Reserve University, National Cancer Institute
3/1/21 → 2/28/25
Project: Research project
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Real-Time Tracking of Gene Therapy by Bioactivated MR contrast Probes
National Institute of Neurological Disorders and Stroke
9/1/20 → 5/31/25
Project: Research project
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Acquisition of a K2 Camera for Soft Matter Transmission Electron Microscopy
Gianneschi, N., Dichtel, W., Dravid, V. P., Farha, O. K., Joester, D., Meade, T. J., Mirkin, C. A., Mrksich, M., Scott, E. A., Stupp, S., Weiss, E. A. & Wu, J.
Office of the Director, National Institutes of Health
8/12/19 → 8/11/24
Project: Research project
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Engineered Nonviral Protein Cages Modified for MR Imaging
Kaster, M. A., Levasseur, M. D., Edwardson, T. G. W., Caldwell, M. A., Hofmann, D., Licciardi, G., Parigi, G., Luchinat, C., Hilvert, D. & Meade, T. J., Feb 20 2023, In: ACS Applied Bio Materials. 6, 2, p. 591-602 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Molecular Engineering of Self-Immolative Bioresponsive MR Probes
Tang, J. H., Li, H., Yuan, C., Parigi, G., Luchinat, C. & Meade, T. J., May 10 2023, In: Journal of the American Chemical Society. 145, 18, p. 10045-10050 6 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Delivery of Targeted Co(III)-DNA Inhibitors of Gli Proteins to Disrupt Hedgehog Signaling
Dukes, M. W., Bajema, E. A., Whittemore, T. J., Holmgren, R. A. & Meade, T. J., Apr 20 2022, In: Bioconjugate Chemistry. 33, 4, p. 643-653 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Functional Disruption of Gli1-DNA Recognition via a Cobalt(III) Complex
Brue, C. R., Dukes, M. W., Masotti, M., Holmgren, R. & Meade, T. J., Apr 20 2022, In: ChemMedChem. 17, 8, e202200025.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Modulation of Hedgehog Signaling for the Treatment of Basal Cell Carcinoma and the Development of Preclinical Models
Dukes, M. W. & Meade, T. J., Oct 2022, In: Biomedicines. 10, 10, 2376.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations
Datasets
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CCDC 938581: Experimental Crystal Structure Determination
Manus, L. M. (Creator), Holbrook, R. J. (Creator), Atesin, T. A. (Creator), Heffern, M. C. (Creator), Harney, A. S. (Creator), Eckermann, A. L. (Creator) & Meade, T. J. (Creator), Cambridge Crystallographic Data Centre, 2013
DOI: 10.5517/cc10hntz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc10hntz&sid=DataCite
Dataset
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NMR Relaxometry data for publication "Engineered Nonviral Protein Cages Modified for MR Imaging"
Kaster, M. A. (Contributor), Levasseur, M. D. (Contributor), Edwardson, T. G. W. (Contributor), Caldwell, M. A. (Contributor), Hofmann, D. (Contributor), Licciardi, G. (Contributor), Parigi, G. (Contributor), Luchinat, C. (Contributor), Hilvert, D. (Contributor) & Meade, T. J. (Contributor), ZENODO, Jan 10 2023
DOI: 10.5281/zenodo.7624051, https://zenodo.org/record/7624051
Dataset
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CCDC 2076267: Experimental Crystal Structure Determination
Tang, J. (Contributor), Li, H. (Contributor), Yuan, C. (Contributor), Parigi, G. (Contributor), Luchinat, C. (Contributor) & Meade, T. J. (Contributor), Cambridge Crystallographic Data Centre, 2023
DOI: 10.5517/ccdc.csd.cc27pjcv, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc27pjcv&sid=DataCite
Dataset
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CCDC 286496: Experimental Crystal Structure Determination
Duimstra, J. A. (Creator), Stern, C. L. (Creator) & Meade, T. J. (Creator), Cambridge Crystallographic Data Centre, 2007
DOI: 10.5517/cc9m3tt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc9m3tt&sid=DataCite
Dataset
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CCDC 1821083: Experimental Crystal Structure Determination
Lilley, L. M. (Creator), Du, K. (Creator), Krzyaniak, M. D. (Creator), Parigi, G. (Creator), Luchinat, C. (Creator), Harris, T. D. (Creator), Meade, T. J. (Creator) & Lilley, L. M. (Creator), Cambridge Crystallographic Data Centre, 2018
DOI: 10.5517/ccdc.csd.cc1z3zmp, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1z3zmp&sid=DataCite
Dataset