• 23225 Citations
1975 …2020

Research output per year

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Research Output

2020

Bone Adaptation in Adult Women Is Related to Loading Dose: A 12-Month Randomized Controlled Trial

Troy, K. L., Mancuso, M. E., Johnson, J. E., Wu, Z., Schnitzer, T. J. & Butler, T. A., Jul 1 2020, In : Journal of Bone and Mineral Research. 35, 7, p. 1300-1312 13 p.

Research output: Contribution to journalArticle

Open Access

Onset and maintenance of efficacy of subcutaneous tanezumab in patients with moderate to severe osteoarthritis of the knee or hip: A 16-week dose-titration study

Schnitzer, T. J., Khan, A., Bessette, L., Davignon, I., Brown, M. T., Pixton, G., Prucka, W. R., Tive, L., Viktrup, L. & West, C. R., Jun 2020, In : Seminars in Arthritis and Rheumatism. 50, 3, p. 387-393 7 p.

Research output: Contribution to journalArticle

Open Access

Prognostics for pain in osteoarthritis: Do clinical measures predict pain after total joint replacement?

Barroso, J., Wakaizumi, K., Reckziegel, D., Pinto-Ramos, J., Schnitzer, T., Galhardo, V. & Apkarian, A. V., 2020, In : PloS one. 15, 1, e0222370.

Research output: Contribution to journalArticle

Open Access

Temporal Factors Associated With Opioid Prescriptions for Patients With Pain Conditions in an Urban Emergency Department

Smith, B. C., Vigotsky, A. D., Apkarian, A. V. & Schnitzer, T. J., Mar 2 2020, In : JAMA network open. 3, 3, p. e200802

Research output: Contribution to journalArticle

Open Access
2019

A Phase II Trial of Lutikizumab, an Anti–Interleukin-1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis

Fleischmann, R. M., Bliddal, H., Blanco, F. J., Schnitzer, T. J., Peterfy, C., Chen, S., Wang, L., Feng, S., Conaghan, P. G., Berenbaum, F., Pelletier, J. P., Martel-Pelletier, J., Vaeterlein, O., Kaeley, G. S., Liu, W., Kosloski, M. P., Levy, G., Zhang, L., Medema, J. K. & Levesque, M. C., Jul 2019, In : Arthritis and Rheumatology. 71, 7, p. 1056-1069 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Applications of Bayesian statistical methodology to clinical trial design: A case study of a phase 2 trial with an interim futility assessment in patients with knee osteoarthritis

Smith, C. L., Jin, Y., Raddad, E., McNearney, T. A., Ni, X., Monteith, D., Brown, R., Deeg, M. A. & Schnitzer, T., Jan 1 2019, In : Pharmaceutical Statistics. 18, 1, p. 39-53 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Deconstructing biomarkers for chronic pain: context- and hypothesis-dependent biomarker types in relation to chronic pain

Reckziegel, D., Vachon-Presseau, E., Petre, B., Schnitzer, T. J., Baliki, M. N. & Apkarian, A. V., May 1 2019, In : Pain. 160, p. S37-S48

Research output: Contribution to journalReview article

3 Scopus citations

Effect of Tanezumab on Joint Pain, Physical Function, and Patient Global Assessment of Osteoarthritis among Patients with Osteoarthritis of the Hip or Knee: A Randomized Clinical Trial

Schnitzer, T. J., Easton, R., Pang, S., Levinson, D. J., Pixton, G., Viktrup, L., Davignon, I., Brown, M. T., West, C. R. & Verburg, K. M., Jul 2 2019, In : JAMA - Journal of the American Medical Association. 322, 1, p. 37-48 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Identification of traits and functional connectivity-based neurotraits of chronic pain

Vachon-Presseau, E., Berger, S. E., Abdullah, T. B., Griffith, J. W., Schnitzer, T. J. & Vania Apkarian, A., Aug 20 2019, In : PLoS biology. 17, 8, e3000349.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Open-label clinical trial of alendronate after teriparatide therapy in people with spinal cord injury and low bone mineral density

Haider, I. T., Simonian, N., Saini, A. S., Leung, F. M., Edwards, W. B. & Schnitzer, T. J., Oct 1 2019, In : Spinal Cord. 57, 10, p. 832-842 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase iii clinical trials in patients with osteoarthritis pain of the knee or hip

Tive, L., Bello, A. E., Radin, D., Schnitzer, T. J., Nguyen, H., Brown, M. T. & West, C. R., Jan 1 2019, In : Journal of Pain Research. 12, p. 975-995 21 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

The Efficacy, Tolerability, and Joint Safety of Fasinumab in Osteoarthritis Pain: A Phase IIb/III Double-Blind, Placebo-Controlled, Randomized Clinical Trial

Dakin, P., DiMartino, S. J., Gao, H., Maloney, J., Kivitz, A. J., Schnitzer, T. J., Stahl, N., Yancopoulos, G. D. & Geba, G. P., Nov 1 2019, In : Arthritis and Rheumatology. 71, 11, p. 1824-1834 11 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

The OMERACT-OARSI core domain set for measurement in clinical trials of hip and/or knee osteoarthritis

Smith, T. O., Hawker, G. A., Hunter, D. J., March, L. M., Boers, M., Shea, B. J., Christensen, R., Guillemin, F., Terwee, C. B., Williamson, P. R., Dodd, S., Roos, E. M., Loeser, R. F., Schnitzer, T. J., Kloppenburg, M., Neogi, T., Ladel, C. H., Kalsi, G., Kaiser, U., Buttel, T. W. & 8 others, Ashford, A. E., Mobasheri, A., Arden, N. K., Tennant, A., Hochberg, M. C., De Wit, M., Tugwell, P. & Conaghan, P. G., Aug 1 2019, In : Journal of Rheumatology. 46, 8, p. 981-989 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Uptake of the OMERACT-OARSI hip and knee osteoarthritis core outcome set: Review of randomized controlled trials from 1997 to 2017

Smith, T. O., Mansfield, M., Hawker, G. A., Hunter, D. J., March, L. M., Boers, M., Shea, B. J., Christensen, R., Guillemin, F., Terwee, C. B., Williamson, P. R., Roos, E. M., Loeser, R. F., Schnitzer, T. J., Kloppenburg, M., Neogi, T., Ladel, C. H., Kalsi, G., Kaiser, U., Buttel, T. W. & 8 others, Ashford, A. E., Mobasheri, A., Arden, N. K., Tennant, A., Hochberg, M. C., De Wit, M., Tugwell, P. & Conaghan, P. G., Aug 1 2019, In : Journal of Rheumatology. 46, 8, p. 976-980 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2018

Bone fragility after spinal cord injury: reductions in stiffness and bone mineral at the distal femur and proximal tibia as a function of time

Haider, I. T., Lobos, S. M., Simonian, N., Schnitzer, T. J. & Edwards, W. B., Dec 1 2018, In : Osteoporosis International. 29, 12, p. 2703-2715 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Brain and psychological determinants of placebo pill response in chronic pain patients

Vachon-Presseau, E., Berger, S. E., Abdullah, T. B., Huang, L., Cecchi, G. A., Griffith, J. W., Schnitzer, T. J. & Apkarian, A. V., Dec 1 2018, In : Nature communications. 9, 1, 3397.

Research output: Contribution to journalArticle

17 Scopus citations

CGRP blockade by galcanezumab was not associated with reductions in signs and symptoms of knee osteoarthritis in a randomized clinical trial

Jin, Y., Smith, C., Monteith, D., Brown, R., Camporeale, A., McNearney, T. A., Deeg, M. A., Raddad, E., Xiao, N., de la Peña, A., Kivitz, A. J. & Schnitzer, T. J., Dec 2018, In : Osteoarthritis and Cartilage. 26, 12, p. 1609-1618 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effects of Teriparatide and Vibration on Bone Mass and Bone Strength in People with Bone Loss and Spinal Cord Injury: A Randomized, Controlled Trial

Edwards, W. B., Simonian, N., Haider, I. T., Anschel, A. S., Chen, D., Gordon, K. E., Gregory, E. K., Kim, K. H., Parachuri, R., Troy, K. L. & Schnitzer, T. J., Oct 2018, In : Journal of Bone and Mineral Research. 33, 10, p. 1729-1740 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Efficacy and safety of single-dose onabotulinumtoxinA in the treatment of symptoms of osteoarthritis of the knee: results of a placebo-controlled, double-blind study

McAlindon, T. E., Schmidt, U., Bugarin, D., Abrams, S., Geib, T., DeGryse, R. E., Kim, K. & Schnitzer, T. J., Oct 2018, In : Osteoarthritis and Cartilage. 26, 10, p. 1291-1299 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hippocampal morphology mediates biased memories of chronic pain

Berger, S. E., Vachon-Presseau, É., Abdullah, T. B., Baria, A. T., Schnitzer, T. J. & Apkarian, A. V., Feb 1 2018, In : Neuroimage. 166, p. 86-98 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Inferring distinct mechanisms in the absence of subjective differences: Placebo and centrally acting analgesic underlie unique brain adaptations

Tétreault, P., Baliki, M. N., Baria, A. T., Bauer, W. R., Schnitzer, T. J. & Apkarian, A. V., May 2018, In : Human Brain Mapping. 39, 5, p. 2210-2223 14 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Tanezumab in the treatment of chronic musculoskeletal conditions

Jayabalan, P. S. & Schnitzer, T. J., Feb 1 2017, In : Expert Opinion on Biological Therapy. 17, 2, p. 245-254 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain

Schnitzer, T. J., Torbey, S., Herrmann, K., Kaushal, G., Yeasted, R. & Vania Apkarian, A., Nov 1 2016, In : Molecular Pain. 12

Research output: Contribution to journalArticle

2 Scopus citations

Brain Connectivity Predicts Placebo Response across Chronic Pain Clinical Trials

Tétreault, P., Mansour, A., Vachon-Presseau, E., Schnitzer, T. J., Apkarian, A. V. & Baliki, M. N., Oct 27 2016, In : PLoS biology. 14, 10, e1002570.

Research output: Contribution to journalArticle

58 Scopus citations

Corticolimbic anatomical characteristics predetermine risk for chronic pain

Vachon-Presseau, E., Tétreault, P., Petre, B., Huang, L., Berger, S. E., Torbey, S., Baria, A. T., Mansour, A. R., Hashmi, J. A., Griffith, J. W., Comasco, E., Schnitzer, T. J., Baliki, M. N. & Apkarian, A. V., Jul 1 2016, In : Brain. 139, 7, p. 1958-1970 13 p.

Research output: Contribution to journalArticle

97 Scopus citations

Efficacy and Safety of Proton-Pump Inhibitors in High-Risk Cardiovascular Subsets of the COGENT Trial

Vaduganathan, M., Cannon, C. P., Cryer, B. L., Liu, Y., Hsieh, W. H., Doros, G., Cohen, M., Lanas, A., Schnitzer, T. J., Shook, T. L., Lapuerta, P., Goldsmith, M. A., Laine, L. & Bhatt, D. L., Sep 1 2016, In : American Journal of Medicine. 129, 9, p. 1002-1005 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy

Bhatt, D. L., Cryer, B. L., Liu, Y., Hsieh, W. H., Doros, G., Cohen, M., Lanas, A., Schnitzer, T. J., Shook, T. L., Lapuerta, P., Goldsmith, M. A., Laine, L., Cannon, C. P. & COGENT Investigators, Apr 12 2016, In : Journal of the American College of Cardiology. 67, 14, p. 1661-1671 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Reply: High Risk of Gastrointestinal Bleeding on Dual Antiplatelet Treatment

Vaduganathan, M., Bhatt, D. L., Cryer, B. L., Liu, Y., Hsieh, W. H., Doros, G., Cohen, M., Lanas, A., Schnitzer, T. J., Shook, T. L., Lapuerta, P., Goldsmith, M. A., Laine, L. & Cannon, C. P., Aug 30 2016, In : Journal of the American College of Cardiology. 68, 9, p. 981-982 2 p.

Research output: Contribution to journalLetter

The emotional brain as a predictor and amplifier of chronic pain

Vachon-Presseau, E., Centeno, M. V., Ren, W., Berger, S. E., Tétreault, P., Ghantous, M., Baria, A., Farmer, M., Baliki, M. N., Schnitzer, T. J. & Apkarian, A. V., 2016, In : Journal of Dental Research. 95, 6, p. 605-612 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Zoledronic Acid Treatment After Acute Spinal Cord Injury: Results of a Randomized, Placebo-Controlled Pilot Trial

Schnitzer, T. J., Kim, K., Marks, J., Yeasted, R., Simonian, N. & Chen, D., Sep 1 2016, In : PM and R. 8, 9, p. 833-843 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015
79 Scopus citations

Bone Imaging and Fracture Risk after Spinal Cord Injury

Edwards, W. B. & Schnitzer, T. J., Oct 7 2015, In : Current Osteoporosis Reports. 13, 5, p. 310-317 8 p.

Research output: Contribution to journalReview article

9 Scopus citations

Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain

Schnitzer, T. J., Ekman, E. F., Spierings, E. L. H., Greenberg, H. S., Smith, M. D., Brown, M. T., West, C. R., Verburg, K. M. & Kvien, T. K., Jun 1 2015, In : Annals of the Rheumatic Diseases. 74, 6, p. 1202-1211 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

OARSI Clinical Trials Recommendations: Key analytic considerations in design, analysis, and reporting of randomized controlled trials in osteoarthritis

Losina, E., Ranstam, J., Collins, J. E., Schnitzer, T. J. & Katz, J. N., Jan 1 2015, In : Osteoarthritis and Cartilage. 23, 5, p. 677-685 9 p.

Research output: Contribution to journalReview article

12 Scopus citations

OARSI Clinical Trials Recommendations: Design, conduct, and reporting of clinical trials for knee osteoarthritis

McAlindon, T. E., Driban, J. B., Henrotin, Y., Hunter, D. J., Jiang, G. L., Skou, S. T., Wang, S. & Schnitzer, T., Jan 1 2015, In : Osteoarthritis and Cartilage. 23, 5, p. 747-760 14 p.

Research output: Contribution to journalReview article

80 Scopus citations

Predicting development of chronic musculoskeletal pain: Contrasting the brain imaging viewpoint with classical models

Apkarian, A. V., Baliki, M. N. & Schnitzer, T. J., Jun 1 2015, Musculoskeletal Pain: Basic Mechanisms and Implications. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Reduction in Torsional Stiffness and Strength at the Proximal Tibia as a Function of Time since Spinal Cord Injury

Edwards, W. B., Simonian, N., Troy, K. L. & Schnitzer, T. J., Aug 1 2015, In : Journal of Bone and Mineral Research. 30, 8, p. 1422-1430 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Smoking increases risk of pain chronification through shared corticostriatal circuitry

Petre, B., Torbey, S., Griffith, J. W., De Oliveira, G., Herrmann, K., Mansour, A., Baria, A. T., Baliki, M. N., Schnitzer, T. J. & Apkarian, A. V., Feb 1 2015, In : Human Brain Mapping. 36, 2, p. 683-694 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: Analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial

Vardi, M., Cryer, B. L., Cohen, M., Lanas, A., Schnitzer, T. J., Lapuerta, P., Goldsmith, M. A., Laine, L., Doros, G., Liu, Y., McIntosh, A. I., Cannon, C. P. & Bhatt, D. L., Aug 1 2015, In : Alimentary Pharmacology and Therapeutics. 42, 3, p. 365-374 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Bone mineral and stiffness loss at the distal femur and proximal tibia in acute spinal cord injury

Edwards, W. B., Schnitzer, T. J. & Troy, K. L., Mar 1 2014, In : Osteoporosis International. 25, 3, p. 1005-1015 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Dual energy X-ray absorptiometry of the knee in spinal cord injury: Methodology and correlation with quantitative computed tomography

McPherson, J. G., Edwards, W. B., Prasad, A., Troy, K. L., Griffith, J. W. & Schnitzer, T. J., Nov 13 2014, In : Spinal Cord. 52, 11, p. 821-825 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Intra-articular hylastan versus steroid for knee osteoarthritis

Housman, L., Arden, N., Schnitzer, T. J., Birbara, C., Conrozier, T., Skrepnik, N., Wei, N., Bockow, B., Waddell, D., Tahir, H., Hammond, A., Goupille, P., Sanson, B. J., Elkins, C. & Bailleul, F., Jul 2014, In : Knee Surgery, Sports Traumatology, Arthroscopy. 22, 7, p. 1684-1692 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reduction in proximal femoral strength in patients with acute spinal cord injury

Edwards, W. B., Schnitzer, T. J. & Troy, K. L., Jan 1 2014, In : Journal of Bone and Mineral Research. 29, 9, p. 2074-2079 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reorganization of hippocampal functional connectivity with transition to chronic back pain

Mutso, A. A., Petre, B., Huang, L., Baliki, M. N., Torbey, S., Herrmann, K. M., Schnitzer, T. J. & Apkarian, V. A., Mar 1 2014, In : Journal of neurophysiology. 111, 5, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

The mechanical consequence of actual bone loss and simulated bone recovery in acute spinal cord injury

Edwards, W. B., Schnitzer, T. J. & Troy, K. L., Mar 1 2014, In : Bone. 60, p. 141-147 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Bone mineral loss at the proximal femur in acute spinal cord injury

Edwards, W. B., Schnitzer, T. J. & Troy, K. L., Sep 1 2013, In : Osteoporosis International. 24, 9, p. 2461-2469 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Brain white matter structural properties predict transition to chronic pain

Mansour, A. R., Baliki, M. N., Huang, L., Torbey, S., Herrmann, K. M., Schnitzer, T. J. & Apkarian, A., Jan 1 2013, In : Pain. 154, 10, p. 2160-2168 9 p.

Research output: Contribution to journalArticle

127 Scopus citations
26 Scopus citations

Shape shifting pain: Chronification of back pain shifts brain representation from nociceptive to emotional circuits

Hashmi, J. A., Baliki, M. N., Huang, L., Baria, A. T., Torbey, S., Hermann, K. M., Schnitzer, T. J. & Apkarian, A. V., Sep 2013, In : Brain. 136, 9, p. 2751-2768 18 p.

Research output: Contribution to journalArticle

278 Scopus citations

Subchondral bone trabecular integrity predicts and changes concurrently with radiographic and magnetic resonance imaging-determined knee osteoarthritis progression

Kraus, V. B., Feng, S., Wang, S., White, S., Ainslie, M., Le Graverand, M. P. H., Brett, A., Eckstein, F., Hunter, D. J., Lane, N. E., Taljanovic, M. S., Schnitzer, T. J. & Charles, H. C., Jul 1 2013, In : Arthritis and rheumatism. 65, 7, p. 1812-1821 10 p.

Research output: Contribution to journalArticle

43 Scopus citations