Research Output per year
Research Output per year
Personal profile
Research Interests
I am interested in using quantitative pharmacologic approaches (modeling and simulation) to improve the understanding of drug disposition and effects in children. Pharmacometric interpretation of both population and clinical trial data can lead to more efficacious and safer treatments as well as provide guidance for the design of efficient, definitive pediatric clinical trials.
Pharmacometrics, Pediatric Clinical Pharmacology
Pediatric Critical Care Medicine, Pediatric Pulmonary Medicine
Certifications and Licenses
| Pediatric Pulmonology | |
| Pediatric Critical Care Medicine | |
| Pediatrics |
Training Experience
| 1975 | Internship, University of Minnesota Medical Center |
| 1977 | Residency, University of Minnesota Medical Center |
| 1979 | Fellowship, University of Minnesota Medical Center |
| 1994 | Fellowship, University of North Carolina School of Medicine |
| 1994 | Fellowship, University of Minnesota Medical Center |
Education/Academic qualification
MD, Medicine, Stanford University
… → 1974
Research interests keywords
- Clinical Pharmacology
- Critical Care
- Pediatrics
- Pharmacokinetics
- Pharmacology
- Respiratory Diseases
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Collaborations and top research areas from the last five years
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Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity
the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, Aug 2022, In: Clinical pharmacology and therapeutics. 112, 2, p. 391-403 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Estimation of Body Fat Percentage for Clinical Pharmacokinetic Studies in Children
Green, T. P., Binns, H. J., Wu, H., Ariza, A. J., Perrin, E. M., Quadri, M., Hornik, C. P. & Cohen-Wolkowiez, M., Mar 2021, In: Clinical and Translational Science. 14, 2, p. 509-517 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Physiologically-Based Pharmacokinetic Modeling Characterizes the CYP3A-Mediated Drug-Drug Interaction Between Fluconazole and Sildenafil in Infants
the Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee, Jan 2021, In: Clinical pharmacology and therapeutics. 109, 1, p. 253-262 10 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants
the Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee, Dec 2021, In: Clinical Pharmacokinetics. 60, 12, p. 1591-1604 14 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Prolonged post-discontinuation antibiotic exposure in very low birth weight neonates at risk for early-onset sepsis
The Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network, May 1 2021, In: Journal of the Pediatric Infectious Diseases Society. 10, 5, p. 615-621 7 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations