Thomas Patrick Shanley

  • 7656 Citations
19952019
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Research Output 1995 2019

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Article
2019
1 Citation (Scopus)

A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome

Flori, H., Sapru, A., Quasney, M. W., Gildengorin, G., Curley, M. A. Q., Matthay, M. A., Dahmer, M. K., Bateman, S. T., Berg, M. D., Borasino, S., Bysani, G. K., Cowl, A. S., Bowens, C. D., Faustino, E. V. S., Fineman, L. D., Godshall, A. J., Hirshberg, E., Kirby, A. L., McLaughlin, G. E., Medar, S. & 10 others, Oren, P. P., Schneider, J. B., Schwarz, A. J., Shanley, T. P., Sorce, L. R., Truemper, E. J., Vander Heyden, M. A., Wittmayer, K., Zuppa, A. & Wypij, D., Apr 17 2019, In : Critical Care. 23, 1, 128.

Research output: Contribution to journalArticle

Open Access
Adult Respiratory Distress Syndrome
Interleukin-8
Respiratory Insufficiency
Pediatrics
Single Nucleotide Polymorphism
1 Citation (Scopus)

Loss of myeloid-specific protein phosphatase 2A enhances lung injury and fibrosis and results in IL-10-dependent sensitization of epithelial cell apoptosis

Sun, L., Hult, E. M., Cornell, T. T., Kim, K. K., Shanley, T. P., Wilke, C. A., Agarwal, M., Gurczynski, S. J., Moore, B. B. & Dahmer, M. K., Jun 1 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 316, 6, p. L1035-L1048

Research output: Contribution to journalArticle

Protein Phosphatase 2
Lung Injury
Interleukin-10
Fibrosis
Epithelial Cells
2 Citations (Scopus)

miR-144-mediated Inhibition of ROCK1 Protects against LPS-induced Lung Endothelial Hyperpermeability

Siddiqui, M. R., Akhtar, S., Shahid, M., Tauseef, M., McDonough, K. & Shanley, T. P., Aug 1 2019, In : American journal of respiratory cell and molecular biology. 61, 2, p. 257-265 9 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
MicroRNAs
Myosin Light Chains
Endothelial cells
Lung

Sedation Management for Critically Ill Children with Pre-Existing Cognitive Impairment

Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators, Mar 1 2019, In : Journal of Pediatrics. 206, p. 204-211.e1

Research output: Contribution to journalArticle

Critical Illness
Pediatric Intensive Care Units
Analgesia
Pediatrics
Substance Withdrawal Syndrome

The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest

Topjian, A. A., Sutton, R. M., Reeder, R. W., Telford, R., Meert, K. L., Yates, A. R., Morgan, R. W., Berger, J. T., Newth, C. J., Carcillo, J. A., McQuillen, P. S., Harrison, R. E., Moler, F. W., Pollack, M. M., Carpenter, T. C., Notterman, D. A., Holubkov, R., Dean, J. M., Nadkarni, V. M., Berg, R. A. & 26 others, Zuppa, A. F., Graham, K., Twelves, C., Diliberto, M. A., Landis, W. P., Tomanio, E., Kwok, J., Bell, M. J., Abraham, A., Sapru, A., Alkhouli, M. F., Heidemann, S., Pawluszka, A., Hall, M. W., Steele, L., Shanley, T. P., Weber, M., Dalton, H. J., Bell, A. L., Mourani, P. M., Malone, K., Locandro, C., Coleman, W., Peterson, A., Thelen, J. & Doctor, A., Aug 1 2019, In : Resuscitation. 141, p. 88-95 8 p.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Heart Arrest
Pediatrics
Hypertension
Survival
2018
2 Citations (Scopus)

Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation

Cashen, K., Reeder, R., Dalton, H. J., Berg, R. A., Shanley, T. P., Newth, C. J. L., Pollack, M. M., Wessel, D., Carcillo, J., Harrison, R., Dean, J. M., Tamburro, R. & Meert, K. L., Sep 1 2018, In : Perfusion (United Kingdom). 33, 6, p. 472-482 11 p.

Research output: Contribution to journalArticle

Intensive care units
Extracorporeal Membrane Oxygenation
Pediatrics
Oxygenation
mortality
7 Citations (Scopus)

Chest compression rates and pediatric in-hospital cardiac arrest survival outcomes

the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators, Sep 1 2018, In : Resuscitation. 130, p. 159-166 8 p.

Research output: Contribution to journalArticle

Pediatric Hospitals
Heart Arrest
Thorax
Guidelines
Survival
1 Citation (Scopus)

Cognitive Development One Year after Infantile Critical Pertussis

Berger, J. T., Villalobos, M. E., Clark, A. E., Holubkov, R., Pollack, M. M., Berg, R. A., Carcillo, J. A., Dalton, H., Harrison, R., Meert, K. L., Newth, C. J. L., Shanley, T. P., Wessel, D. L., Anand, K. J. S., Zimmerman, J. J., Sanders, R. C., Liu, T., Burr, J. S., Willson, D. F., Doctor, A. & 3 others, Dean, J. M., Jenkins, T. L. & Nicholson, C. E., Feb 1 2018, In : Pediatric Critical Care Medicine. 19, 2, p. 89-97 9 p.

Research output: Contribution to journalArticle

Whooping Cough
Learning
Language
National Institute of Child Health and Human Development (U.S.)
Critical Care
3 Citations (Scopus)

Hemolysis during pediatric extracorporeal membrane oxygenation: Associations with circuitry, complications, and mortality

Dalton, H. J., Cashen, K., Reeder, R. W., Berg, R. A., Shanley, T. P., Newth, C. J. L., Pollack, M. M., Wessel, D., Carcillo, J., Harrison, R., Dean, J. M. & Meert, K. L., Jan 1 2018, In : Pediatric Critical Care Medicine. 19, 11, p. 1067-1076 10 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Hemolysis
Pediatrics
Mortality
Hemofiltration
6 Citations (Scopus)

Hyperoxia and hypocapnia during pediatric extracorporeal membrane oxygenation: Associations with complications, mortality, and functional status among survivors

Cashen, K., Reeder, R., Dalton, H. J., Berg, R. A., Shanley, T. P., Newth, C. J. L., Pollack, M. M., Wessel, D., Carcillo, J., Harrison, R., Michael Dean, J., Tamburro, R. & Meert, K. L., Mar 1 2018, In : Pediatric Critical Care Medicine. 19, 3, p. 245-253 9 p.

Research output: Contribution to journalArticle

Hypocapnia
Extracorporeal Membrane Oxygenation
Hyperoxia
Survivors
Pediatrics
3 Citations (Scopus)

RBC Transfusion Practice in Pediatric Extracorporeal Membrane Oxygenation Support

Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN), Jun 1 2018, In : Critical care medicine. 46, 6, p. e552-e559

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Hematocrit
Pediatrics
Hospital Mortality
Hemoglobins
2017
29 Citations (Scopus)

Factors associated with bleeding and thrombosis in children receiving extracorporeal membrane oxygenation

Dalton, H. J., Reeder, R., Garcia-Filion, P., Holubkov, R., Berg, R. A., Zuppa, A., Moler, F. W., Shanley, T., Pollack, M., Newth, C., Berger, J., Wessel, D., Carcillo, J., Bell, M., Heidemann, S., Meert, K. L., Harrison, R., Doctor, A., Tamburro, R. F., Dean, J. M. & 2 others, Jenkins, T. & Nicholson, C., Sep 15 2017, In : American journal of respiratory and critical care medicine. 196, 6, p. 762-771 10 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Thrombosis
Hemorrhage
Hemolysis
Intracranial Hemorrhages
10 Citations (Scopus)

Functional Status of Neonatal and Pediatric Patients after Extracorporeal Membrane Oxygenation

Cashen, K., Reeder, R., Dalton, H. J., Berg, R. A., Shanley, T. P., Newth, C. J. L., Pollack, M. M., Wessel, D., Carcillo, J., Harrison, R., Dean, M. M., Jenkins, T., Meert, K. L. & for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN), Jun 1 2017, In : Pediatric Critical Care Medicine. 18, 6, p. 561-570 10 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Pediatrics
Mortality
Cardiopulmonary Resuscitation
Critical Care
1 Citation (Scopus)

Interaction Between 2 Nutraceutical Treatments and Host Immune Status in the Pediatric Critical Illness Stress-Induced Immune Suppression Comparative Effectiveness Trial

Carcillo, J. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J. S., Zimmerman, J. J., Newth, C. J. L., Harrison, R., Burr, J., Willson, D. F., Nicholson, C., Bell, M. J., Berg, R. A., Shanley, T. P., Heidemann, S. M., Dalton, H., Jenkins, T. L., Doctor, A., Webster, A. & 2 others, Tamburro, R. F. & for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN), Nov 1 2017, In : Journal of Parenteral and Enteral Nutrition. 41, 8, p. 1325-1335 11 p.

Research output: Contribution to journalArticle

Lymphopenia
Dietary Supplements
Critical Illness
Sepsis
Pediatrics
4 Citations (Scopus)

Myeloid-specific gene deletion of protein phosphatase 2A magnifies MyD88- and TRIF-dependent inflammation following endotoxin challenge

Sun, L., Pham, T. T., Cornell, T. T., McDonough, K. L., McHugh, W. M., Blatt, N. B., Dahmer, M. K. & Shanley, T. P., Jan 1 2017, In : Journal of Immunology. 198, 1, p. 404-416 13 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Gene Deletion
Endotoxins
Macrophages
Knockout Mice
12 Citations (Scopus)

Pathophysiology of pediatric multiple organ dysfunction syndrome

Carcillo, J. A., Podd, B., Aneja, R., Weiss, S. L., Hall, M. W., Cornell, T. T., Shanley, T. P., Doughty, L. A. & Nguyen, T. C., Jan 1 2017, In : Pediatric Critical Care Medicine. 18, 3, p. S32-S45

Research output: Contribution to journalArticle

Multiple Organ Failure
Pediatrics
Inflammation
Macrophage Activation Syndrome
Thrombotic Microangiopathies
1 Citation (Scopus)

Potential acceptability of a pediatric ventilator management computer protocol

Eunice Kennedy Shriver National Institute for Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN), Nov 1 2017, In : Pediatric Critical Care Medicine. 18, 11, p. 1027-1034 8 p.

Research output: Contribution to journalArticle

Mechanical Ventilators
Pediatrics
Positive-Pressure Respiration
Adult Respiratory Distress Syndrome
Pressure
2 Citations (Scopus)

Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial

Natale, J. E., Lebet, R., Joseph, J. G., Ulysse, C., Ascenzi, J., Wypij, D., Curley, M. A. Q., Curley, M. A. Q., Wypij, D., Allen, G. L., Angus, D. C., Asaro, L. A., Ascenzi, J. A., Bateman, S. T., Borasino, S., Bowens, C. D., Bysani, G. K., Cheifetz, I. M., Cowl, A. S., Dodson, B. L. & 27 others, Faustino, E. V. S., Fineman, L. D., Flori, H. R., Franck, L. S., Gedeit, R. G., Grant, M. J. C., Harabin, A. L., Haskins-Kiefer, C., Hertzog, J. H., Hutchins, L., Kirby, A. L., Lebet, R. M., Matthay, M. A., McLaughlin, G. E., Natale, J. E., Oren, P. P., Polavarapu, N., Schneider, J. B., Schwarz, A. J., Shanley, T. P., Simone, S., Singer, L. P., Sorce, L. R., Truemper, E. J., Vander Heyden, M. A., Watson, R. S. & Wells, C. R., May 1 2017, In : Journal of Pediatrics. 184, p. 204-208.e1

Research output: Contribution to journalArticle

Parental Consent
Critical Care
Clinical Trials
Pediatrics
Parents
10 Citations (Scopus)

Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol?

Eunice Kennedy Shriver National Institute for Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN), Nov 1 2017, In : Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 18, 11, p. e521-e529

Research output: Contribution to journalArticle

Adult Respiratory Distress Syndrome
Mechanical Ventilators
Artificial Respiration
Pediatrics
Oximetry
2016
5 Citations (Scopus)

Evaluation of advanced cooling therapy’s esophageal cooling device for core temperature control

Naiman, M., Shanley, P., Garrett, F. & Kulstad, E., May 3 2016, In : Expert Review of Medical Devices. 13, 5, p. 423-433 11 p.

Research output: Contribution to journalArticle

Temperature control
Cooling
Equipment and Supplies
Temperature
Modulation
44 Citations (Scopus)

Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs

Berg, R. A., Nadkarni, V. M., Clark, A. E., Moler, F., Meert, K., Harrison, R. E., Newth, C. J. L., Sutton, R. M., Wessel, D. L., Berger, J. T., Carcillo, J., Dalton, H., Heidemann, S., Shanley, T. P., Zuppa, A. F., Doctor, A., Tamburro, R. F., Jenkins, T. L., Dean, J. M., Holubkov, R. & 1 others, Pollack, M. M., Apr 1 2016, In : Critical Care Medicine. 44, 4, p. 798-808 11 p.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Nervous System
Incidence
Survival Rate
Survivors
2 Citations (Scopus)

Inherent Risk Factors for Nosocomial Infection in the Long Stay Critically Ill Child Without Known Baseline Immunocompromise: A Post Hoc Analysis of the CRISIS Trial

Carcillo, J. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J. S., Zimmerman, J., Newth, C. J., Harrison, R., Burr, J., Willson, D. F., Nicholson, C., Bell, M. J., Berg, R. A., Shanley, T. P., Heidemann, S. M., Dalton, H., Jenkins, T. L., Doctor, A. & Webster, A., Nov 1 2016, In : Pediatric Infectious Disease Journal. 35, 11, p. 1182-1186 5 p.

Research output: Contribution to journalArticle

Cross Infection
Critical Illness
Pediatric Intensive Care Units
Lymphopenia
Heart Arrest
12 Citations (Scopus)

Limiting and Withdrawing Life Support in the PICU: For Whom Are These Options Discussed?

Keele, L., Meert, K. L., Berg, R. A., Dalton, H., Newth, C. J. L., Harrison, R., Wessel, D. L., Shanley, T., Carcillo, J., Morrison, W., Funai, T., Holubkov, R., Dean, J. M. & Pollack, M., Feb 1 2016, In : Pediatric Critical Care Medicine. 17, 2, p. 110-120 11 p.

Research output: Contribution to journalArticle

Critical Care
Institutional Practice
Pediatrics
Persistent Vegetative State
Coma
13 Citations (Scopus)

Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure

Oh, B. R., Chen, P., Nidetz, R., McHugh, W., Fu, J., Shanley, T. P., Cornell, T. T. & Kurabayashi, K., Jul 22 2016, In : ACS Sensors. 1, 7, p. 941-948 8 p.

Research output: Contribution to journalArticle

T-cells
drugs
secretions
Immunosuppressive Agents
Cytokines
13 Citations (Scopus)

Patterns of Sedation Weaning in Critically Ill Children Recovering From Acute Respiratory Failure

Best, K. M., Asaro, L. A., Franck, L. S., Wypij, D., Curley, M. A. Q., Allen, G. L., Ascenzi, J. A., Bateman, S. T., Borasino, S., Cheifetz, I. M., Cowl, A. S., Faustino, E. V. S., Fineman, L. D., Flori, H. R., Grant, M. J. C., Hertzog, J. H., Hutchins, L., Kirby, A. L., Natale, J. A. E., Oren, P. P. & 5 others, Polavarapu, N., Shanley, T. P., Simone, S., Sorce, L. R. & Heyden, M. A. V., Jan 1 2016, In : Pediatric Critical Care Medicine. 17, 1, p. 19-29 11 p.

Research output: Contribution to journalArticle

Weaning
Critical Illness
Respiratory Insufficiency
Hypnotics and Sedatives
Opioid Analgesics
4 Citations (Scopus)

Protein phosphatase 2A activation attenuates inflammation in murine models of acute lung injury

McHugh, W. M., Russell, W. W., Fleszar, A. J., Rodenhouse, P. E., Rietberg, S. P., Sun, L., Shanley, T. P. & Cornell, T. T., Jan 1 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 5, p. L903-L912

Research output: Contribution to journalArticle

Protein Phosphatase 2
Acute Lung Injury
Adult Respiratory Distress Syndrome
Inflammation
Neutrophil Infiltration
54 Citations (Scopus)

The Pediatric Risk of Mortality Score: Update 2015

Pollack, M. M., Holubkov, R., Funai, T., Dean, J. M., Berger, J. T., Wessel, D. L., Meert, K., Berg, R. A., Newth, C. J. L., Harrison, R. E., Carcillo, J., Dalton, H., Shanley, T., Jenkins, T. L., Tamburro, R. & Nicholson, C., Jan 1 2016, In : Pediatric Critical Care Medicine. 17, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

Pediatrics
Mortality
Survival
Public Sector
Critical Care
2015
13 Citations (Scopus)

A multibiomarker-based model for estimating the risk of septic acute kidney injury

Wong, H. R., Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J., Checchia, P. A., Meyer, K., Shanley, T. P., Quasney, M., Hall, M., Gedeit, R., Freishtat, R. J., Nowak, J., Raj, S. S., Gertz, S., Dawson, E., Howard, K. & 5 others, Harmon, K., Lahni, P., Frank, E., Hart, K. W. & Lindsell, C. J., Jan 1 2015, In : Critical care medicine. 43, 8, p. 1646-1653 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Septic Shock
Biomarkers
Area Under Curve
Decision Trees
52 Citations (Scopus)

Association of bleeding and thrombosis with outcome in extracorporeal life support

Dalton, H. J., Garcia-Filion, P., Holubkov, R., Moler, F. W., Shanley, T., Heidemann, S., Meert, K., Berg, R. A., Berger, J., Carcillo, J., Newth, C., Harrison, R., Doctor, A., Rycus, P., Dean, J. M., Jenkins, T., Nicholson, C., Eunice Kennedy Shriver National Institute of Child Health and Human Development & Collaborative Pediatric Critical Care Research Network, Feb 13 2015, In : Pediatric Critical Care Medicine. 16, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Thrombosis
Hemorrhage
National Institute of Child Health and Human Development (U.S.)
Critical Care
12 Citations (Scopus)

Citrate modulates lipopolysaccharide-induced monocyte inflammatory responses

Ashbrook, M. J., Mcdonough, K. L., Pituch, J. J., Christopherson, P. L., Cornell, T. T., Selewski, D. T., Shanley, T. P. & Blatt, N. B., Jun 1 2015, In : Clinical and Experimental Immunology. 180, 3, p. 520-530 11 p.

Research output: Contribution to journalArticle

Citric Acid
Lipopolysaccharides
Monocytes
citrate (pro-3S)-lyase
Interleukin-8
110 Citations (Scopus)

Developing a clinically feasible personalized medicine approach to pediatric septic shock

Wong, H. R., Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J., Checchia, P. A., Meyer, K., Shanley, T. P., Quasney, M., Hall, M., Gedeit, R., Freishtat, R. J., Nowak, J., Shekhar, R. S., Gertz, S., Dawson, E., Howard, K. & 4 others, Harmon, K., Beckman, E., Frank, E. & Lindsell, C. J., Feb 1 2015, In : American journal of respiratory and critical care medicine. 191, 3, p. 309-315 7 p.

Research output: Contribution to journalArticle

Precision Medicine
Septic Shock
Pediatrics
Gene Expression
Adrenal Cortex Hormones
3 Citations (Scopus)

Differential expression of the Nrf2-linked genes in pediatric septic shock

Grunwell, J. R., Weiss, S. L., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Shanley, T. P., Bigham, M. T., Fitzgerald, J., Howard, K., Frank, E., Harmon, K. & Wong, H. R., Sep 17 2015, In : Critical Care. 19, 1, 327.

Research output: Contribution to journalArticle

Septic Shock
Pediatrics
Genes
NF-E2 Transcription Factor
Databases
28 Citations (Scopus)

End-of-life practices among tertiary care PICUs in the United States: A multicenter study

Meert, K. L., Keele, L., Morrison, W., Berg, R. A., Dalton, H., Newth, C. J. L., Harrison, R., Wessel, D. L., Shanley, T., Carcillo, J., Clark, A., Holubkov, R., Jenkins, T. L., Doctor, A., Dean, J. M. & Pollack, M., Sep 1 2015, In : Pediatric Critical Care Medicine. 16, 7, p. e231-e238

Research output: Contribution to journalArticle

Tertiary Healthcare
Multicenter Studies
Critical Care
Autopsy
Tissue and Organ Procurement
5 Citations (Scopus)

Language Analysis as a Window to Bereaved Parents’ Emotions During a Parent–Physician Bereavement Meeting

Eggly, S., Manning, M. A., Slatcher, R. B., Berg, R. A., Wessel, D. L., Newth, C. J. L., Shanley, T. P., Harrison, R., Dalton, H., Dean, J. M., Doctor, A., Jenkins, T. & Meert, K. L., Mar 6 2015, In : Journal of Language and Social Psychology. 34, 2, p. 181-199 19 p.

Research output: Contribution to journalArticle

language analysis
Bereavement
Emotions
parents
Language
13 Citations (Scopus)

Meaning making during parent-physician bereavement meetings after a child's death

Meert, K. L., Eggly, S., Kavanaugh, K., Berg, R. A., Wessel, D. L., Newth, C. J. L., Shanley, T. P., Harrison, R., Dalton, H., Michael Dean, J., Doctor, A., Jenkins, T., Park, C. L., Reardon, J., Tomanio, E., Bel, A. L., Villa, M., Pawluszka, A., DiLiberto, M. A., Weber, M. S. & 4 others, Bisping, S., Burr, J., Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network & Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network, Apr 1 2015, In : Health Psychology. 34, 4, p. 453-461 9 p.

Research output: Contribution to journalArticle

Bereavement
Parents
Physicians
Ceremonial Behavior
Pediatric Intensive Care Units
103 Citations (Scopus)

Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays

Chen, P., Chung, M. T., McHugh, W., Nidetz, R., Li, Y., Fu, J., Cornell, T. T., Shanley, T. P. & Kurabayashi, K., Apr 28 2015, In : ACS Nano. 9, 4, p. 4173-4181 9 p.

Research output: Contribution to journalArticle

immunoassay
Microarrays
bioinstrumentation
Biosensors
serums
30 Citations (Scopus)

Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA

Yu, Z. T. F., Guan, H., Cheung, M. K., McHugh, W. M., Cornell, T. T., Shanley, T. P., Kurabayashi, K. & Fu, J., Jun 15 2015, In : Scientific Reports. 5, 11339.

Research output: Contribution to journalArticle

Microfluidics
Immunoassay
Immunophenotyping
Limit of Detection
Flow Cytometry
63 Citations (Scopus)

Simultaneous prediction of new morbidity, mortality, and survival without new morbidity from pediatric intensive care: A new paradigm for outcomes assessment

Pollack, M. M., Holubkov, R., Funai, T., Berger, J. T., Clark, A. E., Meert, K., Berg, R. A., Carcillo, J., Wessel, D. L., Moler, F., Dalton, H., Newth, C. J. L., Shanley, T., Harrison, R. E., Doctor, A., Jenkins, T. L., Tamburro, R. & Dean, J. M., Jan 1 2015, In : Critical care medicine. 43, 8, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

Critical Care
Outcome Assessment (Health Care)
Pediatrics
Morbidity
Survival
3 Citations (Scopus)

Study of protein phosphatase 2a (Pp2a) activity in lps-induced tolerance using fluorescence-based and immunoprecipitation-aided methodology

Sun, L., Pappy, A. L., Pham, T. T. & Shanley, T. P., Jul 7 2015, In : Biomolecules. 5, 3, p. 1284-1301 18 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Immunoprecipitation
Fluorescence
Macrophages
Phosphoric Monoester Hydrolases
5 Citations (Scopus)

Temperature modulation with an esophageal heat transfer device- a pediatric swine model study

Kulstad, E. B., Naiman, M., Shanley, P., Garrett, F., Haryu, T., Waller, D., Azarafrooz, F. & Courtney, D. M., Feb 4 2015, In : BMC Anesthesiology. 15, 1, 16.

Research output: Contribution to journalArticle

Swine
Hot Temperature
Pediatrics
Equipment and Supplies
Temperature
6 Citations (Scopus)

Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network

Frey, L. J., Sward, K. A., Newth, C. J. L., Khemani, R. G., Cryer, M. E., Thelen, J. L., Enriquez, R., Shaoyu, S., Pollack, M. M., Harrison, R. E., Meert, K. L., Berg, R. A., Wessel, D. L., Shanley, T. P., Dalton, H., Carcillo, J., Jenkins, T. L. & Michael Dean, J., Jan 1 2015, In : Journal of the American Medical Informatics Association. 22, 6, p. 1271-1276 6 p.

Research output: Contribution to journalArticle

Critical Care
Pediatrics
Research
Databases
Information Dissemination
2014
26 Citations (Scopus)

Corticosteroids and pediatric septic shock outcomes: A risk stratified analysis

Atkinson, S. J., Cvijanovich, N. Z., Thomas, N. J., Allen, G. L., Anas, N., Bigham, M. T., Hall, M., Freishtat, R. J., Sen, A., Meyer, K., Checchia, P. A., Shanley, T. P., Nowak, J., Quasney, M., Weiss, S. L., Banschbach, S., Beckman, E., Howard, K., Frank, E., Harmon, K. & 3 others, Lahni, P., Lindsell, C. J. & Wong, H. R., Nov 11 2014, In : PloS one. 9, 11, e112702.

Research output: Contribution to journalArticle

septic shock
Pediatrics
risk analysis
adrenal cortex hormones
Septic Shock
37 Citations (Scopus)

Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock

Wong, H. R., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Weiss, S. L., Shanley, T. P., Bigham, M. T., Banschbach, S., Beckman, E., Harmon, K. & Zimmerman, J. J., Apr 15 2014, In : American journal of respiratory and critical care medicine. 189, 8, p. 940-946 7 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Septic Shock
Adrenal Cortex Hormones
Pediatrics
Genes
11 Citations (Scopus)

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock

Weiss, S. L., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Shanley, T. P., Bigham, M. T., Fitzgerald, J., Banschbach, S., Beckman, E., Howard, K., Frank, E., Harmon, K. & Wong, H. R., Nov 19 2014, In : Critical Care. 18, 6, 623.

Research output: Contribution to journalArticle

Septic Shock
Transcriptome
Mitochondrial Genes
Pediatrics
Electron Transport Complex I
9 Citations (Scopus)

Feasibility and perceived benefits of a framework for physician-parent follow-up meetings after a child's death in the PICU

Meert, K. L., Eggly, S., Berg, R. A., Wessel, D. L., Newth, C. J. L., Shanley, T. P., Harrison, R., Dalton, H., Clark, A. E., Dean, J. M., Doctor, A. & Nicholson, C. E., Jan 1 2014, In : Critical Care Medicine. 42, 1, p. 148-157 10 p.

Research output: Contribution to journalArticle

Critical Care
Physicians
Parents
Pediatrics
Research
45 Citations (Scopus)

Integrated nanoplasmonic sensing for cellular functional immunoanalysis using human blood

Oh, B. R., Huang, N. T., Chen, W., Seo, J. H., Chen, P., Cornell, T. T., Shanley, T. P., Fu, J. & Kurabayashi, K., Mar 25 2014, In : ACS Nano. 8, 3, p. 2667-2676 10 p.

Research output: Contribution to journalArticle

Surface plasmon resonance
blood
Assays
Blood
surface plasmon resonance
8 Citations (Scopus)

Interleukin 10 overexpression alters survival in the setting of gram-negative pneumonia following lung contusion

Dolgachev, V. A., Yu, B., Sun, L., Shanley, T. P., Raghavendran, K. & Hemmila, M. R., Jan 1 2014, In : Shock. 41, 4, p. 301-310 10 p.

Research output: Contribution to journalArticle

Contusions
Interleukin-10
Pneumonia
Lung
Survival
80 Citations (Scopus)

Pediatric intensive care outcomes: Development of new morbidities during pediatric critical care

Pollack, M. M., Holubkov, R., Funai, T., Clark, A., Berger, J. T., Meert, K., Newth, C. J. L., Shanley, T., Moler, F., Carcillo, J., Berg, R. A., Dalton, H., Wessel, D. L., Harrison, R. E., Doctor, A., Dean, J. M. & Jenkins, T. L., Nov 10 2014, In : Pediatric Critical Care Medicine. 15, 9, p. 821-827 7 p.

Research output: Contribution to journalArticle

Critical Care
Pediatrics
Morbidity
Mortality
Cardiovascular Diseases
31 Citations (Scopus)

Post-ICU admission fluid balance and pediatric septic shock outcomes: A risk-stratified analysis

Abulebda, K., Cvijanovich, N. Z., Thomas, N. J., Allen, G. L., Anas, N., Bigham, M. T., Hall, M., Freishtat, R. J., Sen, A., Meyer, K., Checchia, P. A., Shanley, T. P., Nowak, J., Quasney, M., Weiss, S. L., Chopra, A., Banschbach, S., Beckman, E., Lindsell, C. J. & Wong, H. R., Feb 1 2014, In : Critical care medicine. 42, 2, p. 397-403 7 p.

Research output: Contribution to journalArticle

Water-Electrolyte Balance
Septic Shock
Pediatrics
Mortality
Biomarkers

Refractory hypoxemia caused by hepatopulmonary syndrome: A case report

Govindan, M. L., Kuo, K. W., Mahani, M. G. & Shanley, T. P., Dec 10 2014, In : Journal of Medical Case Reports. 8, 1, 418.

Research output: Contribution to journalArticle

Hepatopulmonary Syndrome
Biliary Atresia
Liver Transplantation
Echocardiography
Liver Diseases