Thomas Patrick Shanley

  • 7752 Citations
19952019
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Research Output 1995 2019

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2 Citations (Scopus)

Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation

Cashen, K., Reeder, R., Dalton, H. J., Berg, R. A., Shanley, T. P., Newth, C. J. L., Pollack, M. M., Wessel, D., Carcillo, J., Harrison, R., Dean, J. M., Tamburro, R. & Meert, K. L., Sep 1 2018, In : Perfusion (United Kingdom). 33, 6, p. 472-482 11 p.

Research output: Contribution to journalArticle

Intensive care units
Extracorporeal Membrane Oxygenation
Pediatrics
Oxygenation
mortality
4 Citations (Scopus)

Adenosine receptor agonists inhibit Macrophage Inflammatory Protein (MIP)-1α production in immunostimulated macrophages

Shanley, T. P., Haskó, G., Egnaczyk, G., Salzman, A. L. & Szabó, C., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

Purinergic P1 Receptor Agonists
Macrophage Inflammatory Proteins
Macrophages
adenosine
agonists
14 Citations (Scopus)

A multibiomarker-based model for estimating the risk of septic acute kidney injury

Wong, H. R., Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J., Checchia, P. A., Meyer, K., Shanley, T. P., Quasney, M., Hall, M., Gedeit, R., Freishtat, R. J., Nowak, J., Raj, S. S., Gertz, S., Dawson, E., Howard, K. & 5 others, Harmon, K., Lahni, P., Frank, E., Hart, K. W. & Lindsell, C. J., Jan 1 2015, In : Critical care medicine. 43, 8, p. 1646-1653 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Septic Shock
Biomarkers
Area Under Curve
Decision Trees
2 Citations (Scopus)

Anti-thrombin III deficiency primes the endothelial inflam matory response via upregulation of adhesion molecules

Shanley, T. P., Vasi, N., Stark, J. & Morris, C., Dec 1 1999, In : Critical care medicine. 27, 1 SUPPL.

Research output: Contribution to journalArticle

Thrombin
Intercellular Adhesion Molecule-1
Up-Regulation
Human Umbilical Vein Endothelial Cells
Vascular Cell Adhesion Molecule-1
23 Citations (Scopus)

Approach to management of malignant hyperthermia-like syndrome in pediatric diabetes mellitus

Kilbane, B. J., Mehta, S., Backeljauw, P. F., Shanley, T. P. & Crimmins, N. A., Mar 1 2006, In : Pediatric Critical Care Medicine. 7, 2, p. 169-173 5 p.

Research output: Contribution to journalArticle

Malignant Hyperthermia
Hyperglycemic Hyperosmolar Nonketotic Coma
Diabetes Mellitus
Pediatrics
Dantrolene
1 Citation (Scopus)

A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome

Flori, H., Sapru, A., Quasney, M. W., Gildengorin, G., Curley, M. A. Q., Matthay, M. A., Dahmer, M. K., Bateman, S. T., Berg, M. D., Borasino, S., Bysani, G. K., Cowl, A. S., Bowens, C. D., Faustino, E. V. S., Fineman, L. D., Godshall, A. J., Hirshberg, E., Kirby, A. L., McLaughlin, G. E., Medar, S. & 10 others, Oren, P. P., Schneider, J. B., Schwarz, A. J., Shanley, T. P., Sorce, L. R., Truemper, E. J., Vander Heyden, M. A., Wittmayer, K., Zuppa, A. & Wypij, D., Apr 17 2019, In : Critical Care. 23, 1, 128.

Research output: Contribution to journalArticle

Open Access
Adult Respiratory Distress Syndrome
Interleukin-8
Respiratory Insufficiency
Pediatrics
Single Nucleotide Polymorphism
54 Citations (Scopus)

Association of bleeding and thrombosis with outcome in extracorporeal life support

Dalton, H. J., Garcia-Filion, P., Holubkov, R., Moler, F. W., Shanley, T., Heidemann, S., Meert, K., Berg, R. A., Berger, J., Carcillo, J., Newth, C., Harrison, R., Doctor, A., Rycus, P., Dean, J. M., Jenkins, T., Nicholson, C., Eunice Kennedy Shriver National Institute of Child Health and Human Development & Collaborative Pediatric Critical Care Research Network, Feb 13 2015, In : Pediatric Critical Care Medicine. 16, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Thrombosis
Hemorrhage
National Institute of Child Health and Human Development (U.S.)
Critical Care
36 Citations (Scopus)

Ceramide-dependent PP2A regulation of TNFα-induced IL-8 production in respiratory epithelial cells

Cornell, T. T., Hinkovska-Galcheva, V., Sun, L., Cai, Q., Hershenson, M. B., Vanway, S. & Shanley, T. P., May 1 2009, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 296, 5

Research output: Contribution to journalArticle

Ceramides
Interleukin-8
Epithelial Cells
Phosphoprotein Phosphatases
Transcriptional Activation
10 Citations (Scopus)

Ceramide kinase promotes Ca2+ signaling near IgG-opsonized targets and enhances phagolysosomal fusion in COS-1 cells

Hinkovska-Galcheva, V., Clark, A., VanWay, S., Huang, J. B., Hiraoka, M., Abe, A., Borofsky, M., Kunkel, R. G., Shanley, T., Shayman, J. A., Lanni, F., Petty, H. R. & Boxer, L. A., Mar 1 2008, In : Journal of Lipid Research. 49, 3, p. 531-542 12 p.

Research output: Contribution to journalArticle

COS Cells
Phagocytosis
Fusion reactions
Immunoglobulin G
Phagosomes
9 Citations (Scopus)

Characteristics and outcomes of interhospital transfers from level II to level I pediatric intensive care units

Odetola, F. O., Shanley, T. P., Gurney, J. G., Clark, S. J., Dechert, R. E., Freed, G. L. & Davis, M. M., Nov 1 2006, In : Pediatric Critical Care Medicine. 7, 6, p. 536-540 5 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Mortality
Length of Stay
Extracorporeal Membrane Oxygenation
Renal Replacement Therapy
8 Citations (Scopus)

Chest compression rates and pediatric in-hospital cardiac arrest survival outcomes

the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators, Sep 1 2018, In : Resuscitation. 130, p. 159-166 8 p.

Research output: Contribution to journalArticle

Pediatric Hospitals
Heart Arrest
Thorax
Guidelines
Survival
12 Citations (Scopus)

Citrate modulates lipopolysaccharide-induced monocyte inflammatory responses

Ashbrook, M. J., Mcdonough, K. L., Pituch, J. J., Christopherson, P. L., Cornell, T. T., Selewski, D. T., Shanley, T. P. & Blatt, N. B., Jun 1 2015, In : Clinical and Experimental Immunology. 180, 3, p. 520-530 11 p.

Research output: Contribution to journalArticle

Citric Acid
Lipopolysaccharides
Monocytes
citrate (pro-3S)-lyase
Interleukin-8
5 Citations (Scopus)

Clinical course of sepsis in children with acute leukemia admitted to the pediatric intensive care unit

Singer, K., Subbaiah, P., Hutchinson, R., Odetola, F. & Shanley, T. P., Jan 1 2011, In : Pediatric Critical Care Medicine. 12, 6, p. 649-654 6 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Sepsis
Leukemia
Mortality
Steroids
32 Citations (Scopus)

Clinical implications and molecular mechanisms of immunoparalysis after cardiopulmonary bypass

Cornell, T. T., Sun, L., Hall, M. W., Gurney, J. G., Ashbrook, M. J., Ohye, R. G. & Shanley, T. P., May 2012, In : Journal of Thoracic and Cardiovascular Surgery. 143, 5, p. 1160-1166.e1

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Interleukin-10
Immune System
Infection
Epigenomics
640 Citations (Scopus)

Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine

Brierley, J., Carcillo, J. A., Choong, K., Cornell, T., Decaen, A., Deymann, A., Doctor, A., Davis, A., Duff, J., Dugas, M. A., Duncan, A., Evans, B., Feldman, J., Felmet, K., Fisher, G., Frankel, L., Jeffries, H., Greenwald, B., Gutierrez, J., Hall, M. & 33 others, Han, Y. Y., Hanson, J., Hazelzet, J., Hernan, L., Kiff, J., Kissoon, N., Kon, A., Irazusta, J., Lin, J., Lorts, A., Mariscalco, M., Mehta, R., Nadel, S., Nguyen, T., Nicholson, C., Peters, M., Okhuysen-Cawley, R., Poulton, T., Relves, M., Rodriguez, A., Rozenfeld, R., Schnitzler, E., Shanley, T., Skache, S., Skippen, P., Torres, A., Von Dessauer, B., Weingarten, J., Yeh, T., Zaritsky, A., Stojadinovic, B., Zimmerman, J. & Zuckerberg, A., Jan 1 2009, In : Critical care medicine. 37, 2, p. 666-688 23 p.

Research output: Contribution to journalArticle

Critical Care
Septic Shock
Hemodynamics
Medicine
Guidelines
2 Citations (Scopus)

Cognitive Development One Year after Infantile Critical Pertussis

Berger, J. T., Villalobos, M. E., Clark, A. E., Holubkov, R., Pollack, M. M., Berg, R. A., Carcillo, J. A., Dalton, H., Harrison, R., Meert, K. L., Newth, C. J. L., Shanley, T. P., Wessel, D. L., Anand, K. J. S., Zimmerman, J. J., Sanders, R. C., Liu, T., Burr, J. S., Willson, D. F., Doctor, A. & 3 others, Dean, J. M., Jenkins, T. L. & Nicholson, C. E., Feb 1 2018, In : Pediatric Critical Care Medicine. 19, 2, p. 89-97 9 p.

Research output: Contribution to journalArticle

Whooping Cough
Learning
Language
National Institute of Child Health and Human Development (U.S.)
Critical Care
119 Citations (Scopus)

Combined steroid treatment for congenital heart surgery improves oxygen delivery and reduces postbypass inflammatory mediator expression

Schroeder, V. A., Pearl, J. M., Schwartz, S. M., Shanley, T. P., Manning, P. B. & Nelson, D. P., Jun 10 2003, In : Circulation. 107, 22, p. 2823-2828 6 p.

Research output: Contribution to journalArticle

Methylprednisolone
Thoracic Surgery
Steroids
Oxygen
Interleukin-6
54 Citations (Scopus)

Contribution of MKP-1 regulation of p38 to endotoxin tolerance

Nimah, M., Zhao, B., Denenberg, A. G., Bueno, O., Molkentin, J., Wong, H. R. & Shanley, T. P., Jan 1 2005, In : Shock. 23, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

Endotoxins
Dual Specificity Phosphatase 1
Peritoneal Macrophages
p38 Mitogen-Activated Protein Kinases
Nuclear Proteins
28 Citations (Scopus)

Corticosteroids and pediatric septic shock outcomes: A risk stratified analysis

Atkinson, S. J., Cvijanovich, N. Z., Thomas, N. J., Allen, G. L., Anas, N., Bigham, M. T., Hall, M., Freishtat, R. J., Sen, A., Meyer, K., Checchia, P. A., Shanley, T. P., Nowak, J., Quasney, M., Weiss, S. L., Banschbach, S., Beckman, E., Howard, K., Frank, E., Harmon, K. & 3 others, Lahni, P., Lindsell, C. J. & Wong, H. R., Nov 11 2014, In : PloS one. 9, 11, e112702.

Research output: Contribution to journalArticle

septic shock
Pediatrics
risk analysis
adrenal cortex hormones
Septic Shock
37 Citations (Scopus)

Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock

Wong, H. R., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Weiss, S. L., Shanley, T. P., Bigham, M. T., Banschbach, S., Beckman, E., Harmon, K. & Zimmerman, J. J., Apr 15 2014, In : American journal of respiratory and critical care medicine. 189, 8, p. 940-946 7 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Septic Shock
Adrenal Cortex Hormones
Pediatrics
Genes
47 Citations (Scopus)

Critical care for pediatric asthma: Wide care variability and challenges for study

Bratton, S. L., Newth, C. J. L., Zuppa, A. F., Moler, F. W., Meert, K. L., Berg, R. A., Berger, J., Wessel, D., Pollack, M., Harrison, R., Carcillo, J. A., Shanley, T. P., Liu, T., Holubkov, R., Dean, J. M. & Nicholson, C. E., Jul 1 2012, In : Pediatric Critical Care Medicine. 13, 4, p. 407-414 8 p.

Research output: Contribution to journalArticle

Critical Care
Pediatric Intensive Care Units
Asthma
Pediatrics
Research
58 Citations (Scopus)

Critical pertussis illness in children: A multicenter prospective cohort study

Berger, J. T., Carcillo, J. A., Shanley, T. P., Wessel, D. L., Clark, A., Holubkov, R., Meert, K. L., Newth, C. J. L., Berg, R. A., Heidemann, S., Harrison, R., Pollack, M., Dalton, H., Harvill, E., Karanikas, A., Liu, T., Burr, J. S., Doctor, A., Dean, J. M., Jenkins, T. L. & 1 others, Nicholson, C. E., May 1 2013, In : Pediatric Critical Care Medicine. 14, 4, p. 356-365 10 p.

Research output: Contribution to journalArticle

Whooping Cough
Critical Illness
Cohort Studies
Prospective Studies
Pulmonary Hypertension
8 Citations (Scopus)

Cytokine and adhesion molecule requirements for lung injury induced by anti-glomerular basement membrane antibody

Mulligan, M. S., Lentsch, A. B., Shanley, T. P., Miyasaka, M., Johnson, K. J. & Ward, P. A., Aug 26 1998, In : Inflammation. 22, 4, p. 403-417 15 p.

Research output: Contribution to journalArticle

Glomerular Basement Membrane
Lung Injury
Cytokines
Neutrophils
Antibodies
5 Citations (Scopus)
Cytokines
114 Citations (Scopus)

Developing a clinically feasible personalized medicine approach to pediatric septic shock

Wong, H. R., Cvijanovich, N. Z., Anas, N., Allen, G. L., Thomas, N. J., Bigham, M. T., Weiss, S. L., Fitzgerald, J., Checchia, P. A., Meyer, K., Shanley, T. P., Quasney, M., Hall, M., Gedeit, R., Freishtat, R. J., Nowak, J., Shekhar, R. S., Gertz, S., Dawson, E., Howard, K. & 4 others, Harmon, K., Beckman, E., Frank, E. & Lindsell, C. J., Feb 1 2015, In : American journal of respiratory and critical care medicine. 191, 3, p. 309-315 7 p.

Research output: Contribution to journalArticle

Precision Medicine
Septic Shock
Pediatrics
Gene Expression
Adrenal Cortex Hormones
3 Citations (Scopus)

Differential expression of the Nrf2-linked genes in pediatric septic shock

Grunwell, J. R., Weiss, S. L., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Shanley, T. P., Bigham, M. T., Fitzgerald, J., Howard, K., Frank, E., Harmon, K. & Wong, H. R., Sep 17 2015, In : Critical Care. 19, 1, 327.

Research output: Contribution to journalArticle

Septic Shock
Pediatrics
Genes
NF-E2 Transcription Factor
Databases
12 Citations (Scopus)

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock

Weiss, S. L., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Shanley, T. P., Bigham, M. T., Fitzgerald, J., Banschbach, S., Beckman, E., Howard, K., Frank, E., Harmon, K. & Wong, H. R., Nov 19 2014, In : Critical Care. 18, 6, 623.

Research output: Contribution to journalArticle

Septic Shock
Transcriptome
Mitochondrial Genes
Pediatrics
Electron Transport Complex I
56 Citations (Scopus)

Do outcomes vary according to the source of admission to the pediatric intensive care unit?

Odetola, F. O., Rosenberg, A. L., Davis, M. M., Clark, S. J., Dechert, R. E. & Shanley, T. P., Jan 1 2008, In : Pediatric Critical Care Medicine. 9, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Intensive Care Units
Mortality
Hospital Emergency Service
Critical Care
22 Citations (Scopus)

Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation

Sun, L., Cornell, T. T., Levine, A., Berlin, A. A., Hinkovska-Galcheva, V., Fleszar, A. J., Lukacs, N. W. & Shanley, T. P., May 1 2013, In : Clinical and Experimental Immunology. 172, 2, p. 263-279 17 p.

Research output: Contribution to journalArticle

Interleukin-10
Pneumonia
Viruses
Virus Diseases
Respiratory Tract Infections
50 Citations (Scopus)

Effect of IL-10 on neutrophil recruitment and survival after Pseudomonas aeruginosa challenge

Sun, L., Guo, R. F., Newstead, M. W., Standiford, T. J., Macariola, D. R. & Shanley, T. P., Jul 1 2009, In : American journal of respiratory cell and molecular biology. 41, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Neutrophil Infiltration
Interleukin-10
Pseudomonas aeruginosa
Transgenic Mice
Cytokines
32 Citations (Scopus)

Effect of interhospital transfer on resource utilization and outcomes at a tertiary pediatric intensive care unit

Odetola, F. O., Clark, S. J., Gurney, J. G., Dechert, R. E., Shanley, T. P. & Freed, G. L., Sep 1 2009, In : Journal of Critical Care. 24, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Hospital Emergency Service
Mortality
Respiratory Insufficiency
Sepsis
31 Citations (Scopus)

End-of-life practices among tertiary care PICUs in the United States: A multicenter study

Meert, K. L., Keele, L., Morrison, W., Berg, R. A., Dalton, H., Newth, C. J. L., Harrison, R., Wessel, D. L., Shanley, T., Carcillo, J., Clark, A., Holubkov, R., Jenkins, T. L., Doctor, A., Dean, J. M. & Pollack, M., Sep 1 2015, In : Pediatric Critical Care Medicine. 16, 7, p. e231-e238

Research output: Contribution to journalArticle

Tertiary Healthcare
Multicenter Studies
Critical Care
Autopsy
Tissue and Organ Procurement
24 Citations (Scopus)

Epstein-Barr virus-induced hemophagocytic lymphohistiocytosis and X-linked lymphoproliferative disease: A mimicker of sepsis in the Pediatric Intensive Care Unit

Mischler, M., Fleming, G. M., Shanley, T. P., Madden, L., Levine, J., Castle, V., Filipovich, A. H. & Cornell, T. T., May 1 2007, In : Pediatrics. 119, 5, p. e1212-e1218

Research output: Contribution to journalArticle

Hemophagocytic Lymphohistiocytosis
Pediatric Intensive Care Units
Lymphoproliferative Disorders
Human Herpesvirus 4
Sepsis
5 Citations (Scopus)

Evaluation of advanced cooling therapy’s esophageal cooling device for core temperature control

Naiman, M., Shanley, P., Garrett, F. & Kulstad, E., May 3 2016, In : Expert Review of Medical Devices. 13, 5, p. 423-433 11 p.

Research output: Contribution to journalArticle

Temperature control
Cooling
Equipment and Supplies
Temperature
Modulation
76 Citations (Scopus)

Exogenous and endogenous catecholamines inhibit the production of macrophage inflammatory protein (MIP) 1α via a β adrenoceptor mediated mechanism

Haskó, G., Shanley, T. P., Egnaczyk, G., Németh, Z. H., Salzman, A. L., Vizi, E. S. & Szabó, C., Jan 1 1998, In : British Journal of Pharmacology. 125, 6, p. 1297-1303 7 p.

Research output: Contribution to journalArticle

Macrophage Inflammatory Proteins
Adrenergic Receptors
Catecholamines
Rolipram
Norepinephrine
89 Citations (Scopus)

Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells

Aneja, R., Odoms, K., Dunsmore, K., Shanley, T. P. & Wong, H. R., Nov 15 2006, In : Journal of Immunology. 177, 10, p. 7184-7192 9 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Endotoxins
Monocytes
Volunteers
45 Citations (Scopus)

Extracorporeal life support for severe respiratory failure in children with immune compromised conditions

Gupta, M., Shanley, T. P. & Moler, F. W., Jan 1 2008, In : Pediatric Critical Care Medicine. 9, 4, p. 380-385 6 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Respiratory Insufficiency
Survival
Transplants
Nitric Oxide
30 Citations (Scopus)

Factors associated with bleeding and thrombosis in children receiving extracorporeal membrane oxygenation

Dalton, H. J., Reeder, R., Garcia-Filion, P., Holubkov, R., Berg, R. A., Zuppa, A., Moler, F. W., Shanley, T., Pollack, M., Newth, C., Berger, J., Wessel, D., Carcillo, J., Bell, M., Heidemann, S., Meert, K. L., Harrison, R., Doctor, A., Tamburro, R. F., Dean, J. M. & 2 others, Jenkins, T. & Nicholson, C., Sep 15 2017, In : American journal of respiratory and critical care medicine. 196, 6, p. 762-771 10 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Thrombosis
Hemorrhage
Hemolysis
Intracranial Hemorrhages
38 Citations (Scopus)

Fatal and near-fatal asthma in children: The critical care perspective

Newth, C. J. L., Meert, K. L., Clark, A. E., Moler, F. W., Zuppa, A. F., Berg, R. A., Pollack, M. M., Sward, K. A., Berger, J. T., Wessel, D. L., Harrison, R. E., Reardon, J., Carcillo, J. A., Shanley, T. P., Holubkov, R., Dean, J. M., Doctor, A. & Nicholson, C. E., Jan 1 2012, In : Journal of Pediatrics. 161, 2

Research output: Contribution to journalArticle

Critical Care
Pediatric Intensive Care Units
Asthma
Barotrauma
Ventilation
9 Citations (Scopus)

Feasibility and perceived benefits of a framework for physician-parent follow-up meetings after a child's death in the PICU

Meert, K. L., Eggly, S., Berg, R. A., Wessel, D. L., Newth, C. J. L., Shanley, T. P., Harrison, R., Dalton, H., Clark, A. E., Dean, J. M., Doctor, A. & Nicholson, C. E., Jan 1 2014, In : Critical Care Medicine. 42, 1, p. 148-157 10 p.

Research output: Contribution to journalArticle

Critical Care
Physicians
Parents
Pediatrics
Research
95 Citations (Scopus)

Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy

Selewski, D. T., Cornell, T. T., Blatt, N. B., Han, Y. Y., Mottes, T., Kommareddi, M., Gaies, M. G., Annich, G. M., Kershaw, D. B., Shanley, T. P. & Heung, M., Sep 1 2012, In : Critical Care Medicine. 40, 9, p. 2694-2699 6 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Renal Replacement Therapy
Pediatrics
Mortality
Survival

Functional outcomes among survivors of pediatric in-hospital cardiac arrest are associated with baseline neurologic and functional status, but not with diastolic blood pressure during CPR

for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Pediatric Intensive Care Quality of cardiopulmonary resuscitation (PICqCPR) investigators, Oct 1 2019, In : Resuscitation. 143, p. 57-65 9 p.

Research output: Contribution to journalArticle

Pediatric Hospitals
Cardiopulmonary Resuscitation
Heart Arrest
Nervous System
Survivors
11 Citations (Scopus)

Functional Status of Neonatal and Pediatric Patients after Extracorporeal Membrane Oxygenation

Cashen, K., Reeder, R., Dalton, H. J., Berg, R. A., Shanley, T. P., Newth, C. J. L., Pollack, M. M., Wessel, D., Carcillo, J., Harrison, R., Dean, M. M., Jenkins, T., Meert, K. L. & for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN), Jun 1 2017, In : Pediatric Critical Care Medicine. 18, 6, p. 561-570 10 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Pediatrics
Mortality
Cardiopulmonary Resuscitation
Critical Care
34 Citations (Scopus)

Geldanamycin inhibits NF-κB activation and interleukin-8 gene expression in cultured human respiratory epithelium

Malhotra, V., Shanley, T. P., Pittet, J. F., Welch, W. J. & Wong, H. R., Jan 1 2001, In : American Journal of Respiratory Cell and Molecular Biology. 25, 1, p. 92-97 6 p.

Research output: Contribution to journalArticle

Respiratory Mucosa
Interleukin-8
Gene expression
Chemical activation
Gene Expression
155 Citations (Scopus)

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

Wong, H. R., Shanley, T. P., Sakthivel, B., Cvijanovich, N., Lin, R., Allen, G. L., Thomas, N. J., Doctor, A., Kalyanaraman, M., Tofil, N. M., Penfil, S., Monaco, M., Tagavilla, M. A., Odoms, K., Dunsmore, K., Barnes, M. & Aronow, B. J., Jul 18 2007, In : Physiological genomics. 30, 2, p. 146-155 10 p.

Research output: Contribution to journalArticle

Septic Shock
Zinc
Homeostasis
Genome
Pediatrics
97 Citations (Scopus)

Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock

Shanley, T. P., Cvijanovich, N., Lin, R., Allen, G. L., Thomas, N. J., Doctor, A., Kalyanaraman, M., Tofil, N. M., Penfil, S., Monaco, M., Odoms, K., Barnes, M., Sakthivel, B., Aronow, B. J. & Wong, H. R., Sep 1 2007, In : Molecular Medicine. 13, 9-10, p. 495-508 14 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Septic Shock
Genome
Pediatrics
Genes
122 Citations (Scopus)

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum

Wong, H. R., Cvijanovich, N., Allen, G. L., Lin, R., Anas, N., Meyer, K., Freishtat, R. J., Monaco, M., Odoms, K., Sakthivel, B. & Shanley, T. P., Jan 1 2009, In : Critical care medicine. 37, 5, p. 1558-1566 9 p.

Research output: Contribution to journalArticle

Systemic Inflammatory Response Syndrome
Septic Shock
Sepsis
Pediatrics
Genes
107 Citations (Scopus)

Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury

Vogt, B. A., Shanley, T. P., Croatt, A., Alam, J., Johnson, K. J. & Nath, K. A., Nov 1 1996, In : Journal of Clinical Investigation. 98, 9, p. 2139-2145 7 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Inflammation
Kidney
Acute Kidney Injury
Wounds and Injuries
27 Citations (Scopus)

Going back for more: An evaluation of clinical outcomes and characteristics of readmissions to a pediatric intensive care unit

Odetola, F. O., Clark, S. J., Dechert, R. E. & Shanley, T. P., Jan 1 2007, In : Pediatric Critical Care Medicine. 8, 4, p. 343-347 5 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Confidence Intervals
Odds Ratio
Mortality
Critical Illness
28 Citations (Scopus)

Granulocyte-macrophage-colony-stimulating factor-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice

Spight, D., Trapnell, B., Zhao, B., Berclaz, P. & Shanley, T. P., Oct 1 2008, In : Shock. 30, 4, p. 434-442 9 p.

Research output: Contribution to journalArticle

Peritoneal Macrophages
Granulocyte-Macrophage Colony-Stimulating Factor
Peritonitis
Sepsis
Macrophages