Thomas Patrick Shanley

  • 7752 Citations
19952019
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Research Output 1995 2019

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Article
2014

Refractory hypoxemia caused by hepatopulmonary syndrome: A case report

Govindan, M. L., Kuo, K. W., Mahani, M. G. & Shanley, T. P., Dec 10 2014, In : Journal of Medical Case Reports. 8, 1, 418.

Research output: Contribution to journalArticle

Hepatopulmonary Syndrome
Biliary Atresia
Liver Transplantation
Echocardiography
Liver Diseases
62 Citations (Scopus)

Relationship between the functional status scale and the pediatric overall performance category and pediatric cerebral performance category scales

Pollack, M. M., Holubkov, R., Funai, T., Clark, A., Moler, F., Shanley, T., Meert, K., Newth, C. J. L., Carcillo, J., Berger, J. T., Doctor, A., Berg, R. A., Dalton, H., Wessel, D. L., Harrison, R. E., Dean, J. M. & Jenkins, T. L., Jan 1 2014, In : JAMA Pediatrics. 168, 7, p. 671-676 6 p.

Research output: Contribution to journalArticle

Pediatrics
Pediatric Intensive Care Units
Critical Care
Persistent Vegetative State
Coma
41 Citations (Scopus)

Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model

Wong, H. R., Weiss, S. L., Giuliano, J. S., Wainwright, M. S., Cvijanovich, N. Z., Thomas, N. J., Allen, G. L., Anas, N., Bigham, M. T., Hall, M., Freishtat, R. J., Sen, A., Meyer, K., Checchia, P. A., Shanley, T. P., Nowak, J., Quasney, M., Chopra, A., Fitzgerald, J. C., Gedeit, R. & 5 others, Banschbach, S., Beckman, E., Lahn, P., Hart, K. & Lindsell, C. J., Jan 29 2014, In : PLoS One. 9, 1, e86242.

Research output: Contribution to journalArticle

sepsis (infection)
Pediatrics
Biomarkers
biomarkers
Sepsis
26 Citations (Scopus)

The temporal version of the pediatric sepsis biomarker risk model

Wong, H. R., Weiss, S. L., Giuliano, J. S., Wainwright, M. S., Cvijanovich, N. Z., Thomas, N. J., Allen, G. L., Anas, N., Bigham, M. T., Hall, M., Freishtat, R. J., Sen, A., Meyer, K., Checchia, P. A., Shanley, T. P., Nowak, J., Quasney, M., Chopra, A., Fitzgerald, J. C., Gedeit, R. & 5 others, Banschbach, S., Beckman, E., Harmon, K., Lahni, P. & Lindsell, C. J., Mar 13 2014, In : PloS one. 9, 3, e92121.

Research output: Contribution to journalArticle

septic shock
sepsis (infection)
Pediatrics
Biomarkers
Septic Shock
79 Citations (Scopus)

Validation of the KDIGO acute kidney injury criteria in a pediatric critical care population

Selewski, D. T., Cornell, T. T., Heung, M., Troost, J. P., Ehrmann, B. J., Lombel, R. M., Blatt, N. B., Luckritz, K., Hieber, S., Gajarski, R., Kershaw, D. B., Shanley, T. P. & Gipson, D. S., Sep 26 2014, In : Intensive Care Medicine. 40, 10, p. 1481-1488 8 p.

Research output: Contribution to journalArticle

Kidney Diseases
Critical Care
Acute Kidney Injury
Pediatrics
Population
2013
58 Citations (Scopus)

Critical pertussis illness in children: A multicenter prospective cohort study

Berger, J. T., Carcillo, J. A., Shanley, T. P., Wessel, D. L., Clark, A., Holubkov, R., Meert, K. L., Newth, C. J. L., Berg, R. A., Heidemann, S., Harrison, R., Pollack, M., Dalton, H., Harvill, E., Karanikas, A., Liu, T., Burr, J. S., Doctor, A., Dean, J. M., Jenkins, T. L. & 1 others, Nicholson, C. E., May 1 2013, In : Pediatric Critical Care Medicine. 14, 4, p. 356-365 10 p.

Research output: Contribution to journalArticle

Whooping Cough
Critical Illness
Cohort Studies
Prospective Studies
Pulmonary Hypertension
22 Citations (Scopus)

Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation

Sun, L., Cornell, T. T., Levine, A., Berlin, A. A., Hinkovska-Galcheva, V., Fleszar, A. J., Lukacs, N. W. & Shanley, T. P., May 1 2013, In : Clinical and Experimental Immunology. 172, 2, p. 263-279 17 p.

Research output: Contribution to journalArticle

Interleukin-10
Pneumonia
Viruses
Virus Diseases
Respiratory Tract Infections
18 Citations (Scopus)

Improving delivery of continuous renal replacement therapy: Impact of a simulation-based educational intervention

Mottes, T., Owens, T., Niedner, M., Juno, J., Shanley, T. P. & Heung, M., Oct 1 2013, In : Pediatric Critical Care Medicine. 14, 8, p. 747-754 8 p.

Research output: Contribution to journalArticle

Renal Replacement Therapy
Education
Educational Models
Nursing Models
Critical Care Nursing
16 Citations (Scopus)

Induction, maintenance, and reversal of therapeutic hypothermia with an esophageal heat transfer device

Kulstad, E., Metzger, A. K., Courtney, D. M., Rees, J., Shanley, T. P., Matsuura, T., McKnite, S. & Lurie, K., Nov 1 2013, In : Resuscitation. 84, 11, p. 1619-1624 6 p.

Research output: Contribution to journalArticle

Induced Hypothermia
Hot Temperature
Maintenance
Equipment and Supplies
Temperature
15 Citations (Scopus)

Public Participation in, and Awareness about, Medical Research Opportunities in the Era of Clinical and Translational Research

Davis, M. M., Clark, S. J., Butchart, A. T., Singer, D. C., Shanley, T. P. & Gipson, D. S., Apr 1 2013, In : Clinical and Translational Science. 6, 2, p. 88-93 6 p.

Research output: Contribution to journalArticle

Translational Medical Research
Biomedical Research
Parents
Education
Social Conditions
53 Citations (Scopus)

Ratio of PICU versus ward cardiopulmonary resuscitation events is increasing

Berg, R. A., Sutton, R. M., Holubkov, R., Nicholson, C. E., Dean, J. M., Harrison, R., Heidemann, S., Meert, K., Newth, C., Moler, F., Pollack, M., Dalton, H., Doctor, A., Wessel, D., Berger, J., Shanley, T., Carcillo, J. & Nadkarni, V. M., Oct 1 2013, In : Critical Care Medicine. 41, 10, p. 2292-2297 6 p.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Patients' Rooms
Pediatric Hospitals
Pediatrics
Resuscitation
31 Citations (Scopus)

Surface-Micromachined Microfiltration Membranes for Efficient Isolation and Functional Immunophenotyping of Subpopulations of Immune Cells

Chen, W., Huang, N. T., Oh, B., Lam, R. H. W., Fan, R., Cornell, T. T., Shanley, T. P., Kurabayashi, K. & Fu, J., Jan 1 2013, In : Advanced Healthcare Materials. 2, 7, p. 965-975 11 p.

Research output: Contribution to journalArticle

Immunophenotyping
Microfiltration
Membranes
Cellular Immunity
Blood Cells
16 Citations (Scopus)

The ideal time interval for critical care severity-of-illness assessment.

Pollack, M. M., Dean, J. M., Butler, J., Holubkov, R., Doctor, A., Meert, K. L., Newth, C. J. L., Berg, R. A., Moler, F., Dalton, H., Wessel, D. L., Berger, J., Harrison, R. E., Carcillo, J. A., Shanley, T. P. & Nicholson, C. E., Jan 1 2013, In : Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14, 5, p. 448-453 6 p.

Research output: Contribution to journalArticle

Critical Care
Pediatrics
Mortality
Observation
Partial Thromboplastin Time
8 Citations (Scopus)

The use of extracorporeal membrane oxygenation in pediatric patients with sickle cell disease

Kuo, K. W., Cornell, T. T., Shanley, T. P., Odetola, F. O. & Annich, G. M., Sep 1 2013, In : Perfusion (United Kingdom). 28, 5, p. 424-432 9 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Pediatrics
Oxygenation
Sickle Cell Anemia
Disease
4 Citations (Scopus)

Tristetraprolin Mediates Radiation-Induced TNF-α Production in Lung Macrophages

Ray, D., Shukla, S., Allam, U. S., Helman, A., Ramanand, S. G., Tran, L., Bassetti, M., Krishnamurthy, P. M., Rumschlag, M., Paulsen, M., Sun, L., Shanley, T. P., Ljungman, M., Nyati, M. K., Zhang, M. & Lawrence, T. S., Feb 28 2013, In : PloS one. 8, 2, e57290.

Research output: Contribution to journalArticle

Tristetraprolin
Macrophages
tumor necrosis factor-alpha
macrophages
Tumor Necrosis Factor-alpha
2012
32 Citations (Scopus)

Clinical implications and molecular mechanisms of immunoparalysis after cardiopulmonary bypass

Cornell, T. T., Sun, L., Hall, M. W., Gurney, J. G., Ashbrook, M. J., Ohye, R. G. & Shanley, T. P., May 2012, In : Journal of Thoracic and Cardiovascular Surgery. 143, 5, p. 1160-1166.e1

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Interleukin-10
Immune System
Infection
Epigenomics
47 Citations (Scopus)

Critical care for pediatric asthma: Wide care variability and challenges for study

Bratton, S. L., Newth, C. J. L., Zuppa, A. F., Moler, F. W., Meert, K. L., Berg, R. A., Berger, J., Wessel, D., Pollack, M., Harrison, R., Carcillo, J. A., Shanley, T. P., Liu, T., Holubkov, R., Dean, J. M. & Nicholson, C. E., Jul 1 2012, In : Pediatric Critical Care Medicine. 13, 4, p. 407-414 8 p.

Research output: Contribution to journalArticle

Critical Care
Pediatric Intensive Care Units
Asthma
Pediatrics
Research
38 Citations (Scopus)

Fatal and near-fatal asthma in children: The critical care perspective

Newth, C. J. L., Meert, K. L., Clark, A. E., Moler, F. W., Zuppa, A. F., Berg, R. A., Pollack, M. M., Sward, K. A., Berger, J. T., Wessel, D. L., Harrison, R. E., Reardon, J., Carcillo, J. A., Shanley, T. P., Holubkov, R., Dean, J. M., Doctor, A. & Nicholson, C. E., Jan 1 2012, In : Journal of Pediatrics. 161, 2

Research output: Contribution to journalArticle

Critical Care
Pediatric Intensive Care Units
Asthma
Barotrauma
Ventilation
95 Citations (Scopus)

Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy

Selewski, D. T., Cornell, T. T., Blatt, N. B., Han, Y. Y., Mottes, T., Kommareddi, M., Gaies, M. G., Annich, G. M., Kershaw, D. B., Shanley, T. P. & Heung, M., Sep 1 2012, In : Critical Care Medicine. 40, 9, p. 2694-2699 6 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Renal Replacement Therapy
Pediatrics
Mortality
Survival
54 Citations (Scopus)

Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children

Wong, H. R., Cvijanovich, N. Z., Hall, M., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Lin, R., Bigham, M. T., Sen, A., Nowak, J., Quasney, M., Henricksen, J. W., Chopra, A., Banschbach, S., Beckman, E., Harmon, K., Lahni, P. & 1 others, Shanley, T. P., Oct 26 2012, In : Critical Care. 16, 5, R213.

Research output: Contribution to journalArticle

Interleukin-27
Systemic Inflammatory Response Syndrome
Bacterial Infections
Critical Illness
Biomarkers
21 Citations (Scopus)

Mitogen-activated protein kinase phosphatase 2, MKP-2, regulates early inflammation in acute lung injury

Cornell, T. T., Fleszar, A., McHugh, W., Blatt, N. B., LeVine, A. M. & Shanley, T. P., Aug 1 2012, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 303, 3

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Phosphatases
Protein Phosphatase 2
Acute Lung Injury
Mitogen-Activated Protein Kinase 1
Neutrophil Infiltration
12 Citations (Scopus)
Health
Maintenance
Research Personnel
Education
National Center for Advancing Translational Sciences (U.S.)
88 Citations (Scopus)

The pediatric sepsis biomarker risk model

Wong, H. R., Salisbury, S., Xiao, Q., Cvijanovich, N. Z., Hall, M., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Lin, R., Shanley, T. P., Bigham, M. T., Sen, A., Nowak, J., Quasney, M., Henricksen, J. W., Chopra, A., Banschbach, S. & 4 others, Beckman, E., Harmon, K., Lahni, P. & Lindsell, C. J., Oct 1 2012, In : Critical Care. 16, 5, R174.

Research output: Contribution to journalArticle

Septic Shock
Sepsis
Biomarkers
Pediatrics
Decision Trees
5 Citations (Scopus)

Tracking the impact of the national institutes of health clinical and translational science awards on child health research: Developing and evaluating a measurement strategy

Huskins, W. C., Sullivan, C. D., Wang, J., Aitken, M., Alexander, S. R., Epstein, L. G., Hoberman, A., Neufeld, E., Philipps, A., Shanley, T. P., Szilagyi, P., Purucker, M. & Barkin, S. L., May 1 2012, In : Pediatric research. 71, 5, p. 619-624 6 p.

Research output: Contribution to journalArticle

Program Development
National Institutes of Health (U.S.)
Program Evaluation
Child Welfare
Research
2011
5 Citations (Scopus)

Clinical course of sepsis in children with acute leukemia admitted to the pediatric intensive care unit

Singer, K., Subbaiah, P., Hutchinson, R., Odetola, F. & Shanley, T. P., Jan 1 2011, In : Pediatric Critical Care Medicine. 12, 6, p. 649-654 6 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Sepsis
Leukemia
Mortality
Steroids
26 Citations (Scopus)

Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray

Basu, R. K., Standage, S. W., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Lin, R., Shanley, T. P., Bigham, M. T., Wheeler, D. S., Devarajan, P., Goldstein, S. L. & Wong, H. R., Nov 18 2011, In : Critical Care. 15, 6, R273.

Research output: Contribution to journalArticle

Septic Shock
Acute Kidney Injury
Biomarkers
Kidney
Wounds and Injuries
123 Citations (Scopus)

IL-17Induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease

Mukherjee, S., Lindell, D. M., Berlin, A. A., Morris, S. B., Shanley, T. P., Hershenson, M. B. & Lukacs, N. W., Jul 1 2011, In : American Journal of Pathology. 179, 1, p. 248-258 11 p.

Research output: Contribution to journalArticle

Interleukin-17
Virus Diseases
Respiratory Tract Infections
Disease Progression
Lung
48 Citations (Scopus)

Inpatient health care utilization for children dependent on long-term mechanical ventilation

Benneyworth, B. D., Gebremariam, A., Clark, S. J., Shanley, T. P. & Davis, M. M., Jun 1 2011, In : Pediatrics. 127, 6

Research output: Contribution to journalArticle

Patient Acceptance of Health Care
Artificial Respiration
Inpatients
Hospital Charges
Health Services Research
122 Citations (Scopus)

New concepts of IL-10-induced lung fibrosis: Fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis

Sun, L., Louie, M. C., Vannella, K. M., Wilke, C. A., Levine, A. M., Moore, B. B. & Shanley, T. P., Mar 1 2011, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 300, 3

Research output: Contribution to journalArticle

Interleukin-10
Fibrosis
Lung
Macrophages
Bronchoalveolar Lavage
65 Citations (Scopus)

The influence of developmental age on the early transcriptomic response of children with septic shock

Wynn, J. L., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Lin, R., Shanley, T. P., Bigham, M. T., Banschbach, S., Beckman, E. & Wong, H. R., Nov 1 2011, In : Molecular Medicine. 17, 11, p. 1146-1156 11 p.

Research output: Contribution to journalArticle

Septic Shock
Newborn Infant
Transcriptome
Pediatric Intensive Care Units
Genome
59 Citations (Scopus)

Validation of a gene expression-based subclassification strategy for pediatric septic shock

Wong, H. R., Cvijanovich, N. Z., Allen, G. L., Thomas, N. J., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Lin, R., Shanley, T. P., Bigham, M. T., Wheeler, D. S., Doughty, L. A., Tegtmeyer, K., Poynter, S. E., Kaplan, J. M., Chima, R. S., Stalets, E., Basu, R. K., Varisco, B. M. & 1 others, Barr, F. E., Jan 1 2011, In : Critical Care Medicine. 39, 11, p. 2511-2517 7 p.

Research output: Contribution to journalArticle

Septic Shock
Pediatrics
Gene Expression
Transcriptome
Pediatric Intensive Care Units
84 Citations (Scopus)

Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy

Selewski, D. T., Cornell, T. T., Lombel, R. M., Blatt, N. B., Han, Y. Y., Mottes, T., Kommareddi, M., Kershaw, D. B., Shanley, T. P. & Heung, M., Jul 1 2011, In : Intensive Care Medicine. 37, 7, p. 1166-1173 8 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Renal Replacement Therapy
Weights and Measures
Mortality
Water-Electrolyte Balance
2010
43 Citations (Scopus)

Leukocyte subset-derived genomewide expression profiles in pediatric septic shock

Wong, H. R., Freishtat, R. J., Monaco, M., Odoms, K. & Shanley, T. P., Jan 1 2010, In : Pediatric Critical Care Medicine. 11, 3, p. 349-355 7 p.

Research output: Contribution to journalArticle

Septic Shock
Leukocytes
RNA
Pediatrics
Gene Regulatory Networks
38 Citations (Scopus)

Mitogen-activated protein kinase phosphatase 2 regulates the inflammatory response in sepsis

Cornell, T. T., Rodenhouse, P., Cai, Q., Sun, L. & Shanley, T. P., Jun 1 2010, In : Infection and immunity. 78, 6, p. 2868-2876 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Phosphatases
Dual Specificity Phosphatase 1
Protein Phosphatase 2
Mitogen-Activated Protein Kinase 1
Sepsis
2009
36 Citations (Scopus)

Ceramide-dependent PP2A regulation of TNFα-induced IL-8 production in respiratory epithelial cells

Cornell, T. T., Hinkovska-Galcheva, V., Sun, L., Cai, Q., Hershenson, M. B., Vanway, S. & Shanley, T. P., May 1 2009, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 296, 5

Research output: Contribution to journalArticle

Ceramides
Interleukin-8
Epithelial Cells
Phosphoprotein Phosphatases
Transcriptional Activation
640 Citations (Scopus)

Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine

Brierley, J., Carcillo, J. A., Choong, K., Cornell, T., Decaen, A., Deymann, A., Doctor, A., Davis, A., Duff, J., Dugas, M. A., Duncan, A., Evans, B., Feldman, J., Felmet, K., Fisher, G., Frankel, L., Jeffries, H., Greenwald, B., Gutierrez, J., Hall, M. & 33 others, Han, Y. Y., Hanson, J., Hazelzet, J., Hernan, L., Kiff, J., Kissoon, N., Kon, A., Irazusta, J., Lin, J., Lorts, A., Mariscalco, M., Mehta, R., Nadel, S., Nguyen, T., Nicholson, C., Peters, M., Okhuysen-Cawley, R., Poulton, T., Relves, M., Rodriguez, A., Rozenfeld, R., Schnitzler, E., Shanley, T., Skache, S., Skippen, P., Torres, A., Von Dessauer, B., Weingarten, J., Yeh, T., Zaritsky, A., Stojadinovic, B., Zimmerman, J. & Zuckerberg, A., Jan 1 2009, In : Critical care medicine. 37, 2, p. 666-688 23 p.

Research output: Contribution to journalArticle

Critical Care
Septic Shock
Hemodynamics
Medicine
Guidelines
50 Citations (Scopus)

Effect of IL-10 on neutrophil recruitment and survival after Pseudomonas aeruginosa challenge

Sun, L., Guo, R. F., Newstead, M. W., Standiford, T. J., Macariola, D. R. & Shanley, T. P., Jul 1 2009, In : American journal of respiratory cell and molecular biology. 41, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Neutrophil Infiltration
Interleukin-10
Pseudomonas aeruginosa
Transgenic Mice
Cytokines
32 Citations (Scopus)

Effect of interhospital transfer on resource utilization and outcomes at a tertiary pediatric intensive care unit

Odetola, F. O., Clark, S. J., Gurney, J. G., Dechert, R. E., Shanley, T. P. & Freed, G. L., Sep 1 2009, In : Journal of Critical Care. 24, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Hospital Emergency Service
Mortality
Respiratory Insufficiency
Sepsis
122 Citations (Scopus)

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum

Wong, H. R., Cvijanovich, N., Allen, G. L., Lin, R., Anas, N., Meyer, K., Freishtat, R. J., Monaco, M., Odoms, K., Sakthivel, B. & Shanley, T. P., Jan 1 2009, In : Critical care medicine. 37, 5, p. 1558-1566 9 p.

Research output: Contribution to journalArticle

Systemic Inflammatory Response Syndrome
Septic Shock
Sepsis
Pediatrics
Genes
107 Citations (Scopus)

Identification of pediatric septic shock subclasses based on genome-wide expression profiling

Wong, H. R., Cvijanovich, N., Lin, R., Allen, G. L., Thomas, N. J., Willson, D. F., Freishtat, R. J., Anas, N., Meyer, K., Checchia, P. A., Monaco, M., Odom, K. & Shanley, T. P., Jul 22 2009, In : BMC Medicine. 7, 34.

Research output: Contribution to journalArticle

Septic Shock
Genome
Pediatrics
Genes
Cluster Analysis
2008
10 Citations (Scopus)

Ceramide kinase promotes Ca2+ signaling near IgG-opsonized targets and enhances phagolysosomal fusion in COS-1 cells

Hinkovska-Galcheva, V., Clark, A., VanWay, S., Huang, J. B., Hiraoka, M., Abe, A., Borofsky, M., Kunkel, R. G., Shanley, T., Shayman, J. A., Lanni, F., Petty, H. R. & Boxer, L. A., Mar 1 2008, In : Journal of Lipid Research. 49, 3, p. 531-542 12 p.

Research output: Contribution to journalArticle

COS Cells
Phagocytosis
Fusion reactions
Immunoglobulin G
Phagosomes
56 Citations (Scopus)

Do outcomes vary according to the source of admission to the pediatric intensive care unit?

Odetola, F. O., Rosenberg, A. L., Davis, M. M., Clark, S. J., Dechert, R. E. & Shanley, T. P., Jan 1 2008, In : Pediatric Critical Care Medicine. 9, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Intensive Care Units
Mortality
Hospital Emergency Service
Critical Care
45 Citations (Scopus)

Extracorporeal life support for severe respiratory failure in children with immune compromised conditions

Gupta, M., Shanley, T. P. & Moler, F. W., Jan 1 2008, In : Pediatric Critical Care Medicine. 9, 4, p. 380-385 6 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Respiratory Insufficiency
Survival
Transplants
Nitric Oxide
28 Citations (Scopus)

Granulocyte-macrophage-colony-stimulating factor-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice

Spight, D., Trapnell, B., Zhao, B., Berclaz, P. & Shanley, T. P., Oct 1 2008, In : Shock. 30, 4, p. 434-442 9 p.

Research output: Contribution to journalArticle

Peritoneal Macrophages
Granulocyte-Macrophage Colony-Stimulating Factor
Peritonitis
Sepsis
Macrophages
27 Citations (Scopus)

PP2A regulates upstream members of the c-jun N-terminal kinase mitogen-activated protein kinase signaling pathway

Zhao, B., Sun, L., Haas, M., Denenberg, A. G., Wong, H. R. & Shanley, T. P., Feb 1 2008, In : Shock. 29, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinases
MAP Kinase Kinase Kinases
Phosphotransferases
Monocytes
62 Citations (Scopus)

Validating the genomic signature of pediatric septic shock

Cvijanovich, N., Shanley, T. P., Lin, R., Allen, G. L., Thomas, N. J., Checchia, P., Anas, N., Freishtat, R. J., Monaco, M., Odoms, K., Sakthivel, B. & Wong, H. R., Jun 1 2008, In : Physiological Genomics. 34, 1, p. 127-134 8 p.

Research output: Contribution to journalArticle

Septic Shock
Pediatrics
Genes
Genome
Datasets
2007
24 Citations (Scopus)

Epstein-Barr virus-induced hemophagocytic lymphohistiocytosis and X-linked lymphoproliferative disease: A mimicker of sepsis in the Pediatric Intensive Care Unit

Mischler, M., Fleming, G. M., Shanley, T. P., Madden, L., Levine, J., Castle, V., Filipovich, A. H. & Cornell, T. T., May 1 2007, In : Pediatrics. 119, 5

Research output: Contribution to journalArticle

Hemophagocytic Lymphohistiocytosis
Pediatric Intensive Care Units
Lymphoproliferative Disorders
Human Herpesvirus 4
Sepsis
155 Citations (Scopus)

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

Wong, H. R., Shanley, T. P., Sakthivel, B., Cvijanovich, N., Lin, R., Allen, G. L., Thomas, N. J., Doctor, A., Kalyanaraman, M., Tofil, N. M., Penfil, S., Monaco, M., Tagavilla, M. A., Odoms, K., Dunsmore, K., Barnes, M. & Aronow, B. J., Jul 18 2007, In : Physiological genomics. 30, 2, p. 146-155 10 p.

Research output: Contribution to journalArticle

Septic Shock
Zinc
Homeostasis
Genome
Pediatrics
97 Citations (Scopus)

Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock

Shanley, T. P., Cvijanovich, N., Lin, R., Allen, G. L., Thomas, N. J., Doctor, A., Kalyanaraman, M., Tofil, N. M., Penfil, S., Monaco, M., Odoms, K., Barnes, M., Sakthivel, B., Aronow, B. J. & Wong, H. R., Sep 1 2007, In : Molecular Medicine. 13, 9-10, p. 495-508 14 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Septic Shock
Genome
Pediatrics
Genes
27 Citations (Scopus)

Going back for more: An evaluation of clinical outcomes and characteristics of readmissions to a pediatric intensive care unit

Odetola, F. O., Clark, S. J., Dechert, R. E. & Shanley, T. P., Jan 1 2007, In : Pediatric Critical Care Medicine. 8, 4, p. 343-347 5 p.

Research output: Contribution to journalArticle

Pediatric Intensive Care Units
Confidence Intervals
Odds Ratio
Mortality
Critical Illness