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Research Output 1978 2019

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2019
3 Citations (Scopus)

Arsenoplatin-1 Is a Dual Pharmacophore Anticancer Agent

Miodragović, D., Merlino, A., Swindell, E. P., Bogachkov, A., Ahn, R. W., Abuhadba, S., Ferraro, G., Marzo, T., Mazar, A. P., Messori, L. & O'Halloran, T. V., Apr 24 2019, In : Journal of the American Chemical Society. 141, 16, p. 6453-6457 5 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
DNA
Arsenic
Cisplatin
Tumors

Bovine eggs release zinc in response to parthenogenetic and sperm-induced egg activation

Que, E. L., Duncan, F. E., Lee, H. C., Hornick, J. E., Vogt, S., Fissore, R. A., O'Halloran, T. V. & Woodruff, T. K., Mar 15 2019, In : Theriogenology. 127, p. 41-48 8 p.

Research output: Contribution to journalArticle

Eggs
Ovum
Spermatozoa
Zinc
zinc

Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation

Stephens, A. D., Liu, P. Z., Kandula, V., Chen, H., Almassalha, L. M., Herman, C., Backman, V., O'Halloran, T. V., Adam, S. A., Goldman, R., Banigan, E. J. & Marko, J. F., Aug 1 2019, In : Molecular biology of the cell. 30, 17, p. 2320-2330 11 p.

Research output: Contribution to journalArticle

Open Access
Heterochromatin
Mechanics
Chromatin
Ion Channels
Cations
1 Citation (Scopus)

Whole-body imaging of cell death provides a systemic, minimally invasive, dynamic, and near-real time indicator for chemotherapeutic drug toxicity

Johnson, S. E., Ugolkov, A., Haney, C. R., Bondarenko, G., Li, L., Waters, E. A., Bergan, R., Tran, A., O'Halloran, T. V., Mazar, A. & Zhao, M., Feb 15 2019, In : Clinical Cancer Research. 25, 4, p. 1331-1342 12 p.

Research output: Contribution to journalArticle

Whole Body Imaging
Drug-Related Side Effects and Adverse Reactions
Cell Death
Drug Therapy
Toxicology
2018
3 Citations (Scopus)

9-ING-41, a small-molecule glycogen synthase kinase-3 inhibitor, is active in neuroblastoma

Ugolkov, A. V., Bondarenko, G. I., Dubrovskyi, O., Berbegall, A. P., Navarro, S., Noguera, R., O'Halloran, T. V., Hendrix, M. J., Giles, F. J. & Mazar, A. P., Sep 1 2018, In : Anti-Cancer Drugs. 29, 8, p. 717-724 8 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Neuroblastoma
irinotecan
Heterografts
Pediatrics
2 Citations (Scopus)

Aberrant expression of glycogen synthase kinase-3β in human breast and head and neck cancer

Ugolkov, A. V., Matsangou, M., Taxter, T. J., O'Halloran, T. V., Cryns, V. L., Giles, F. J. & Mazar, A. P., Nov 1 2018, In : Oncology Letters. 16, 5, p. 6437-6444 8 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Head and Neck Neoplasms
Breast Neoplasms
Breast
Protein-Serine-Threonine Kinases
3 Citations (Scopus)

A new role for Zinc limitation in bacterial pathogenicity: Modulation of α-hemolysin from uropathogenic Escherichia coli

Velasco, E., Wang, S., Sanet, M., Fernández-Vázquez, J., Jové, D., Glaría, E., Valledor, A. F., O'Halloran, T. V. & Balsalobre, C., Dec 1 2018, In : Scientific reports. 8, 1, 6535.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Hemolysin Proteins
Operon
Virulence
Zinc
2017
8 Citations (Scopus)

Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models

Ugolkov, A., Qiang, W., Bondarenko, G., Procissi, D., Gaisina, I., James, C. D., Chandler, J. P., Kozikowski, A., Gunosewoyo, H., O'Halloran, T. V., Raizer, J. J. & Mazar, A. P., Aug 1 2017, In : Translational Oncology. 10, 4, p. 669-678 10 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Glioblastoma
Heterografts
Combination Drug Therapy
Survival
9 Citations (Scopus)

Macrogenomic engineering via modulation of the scaling of chromatin packing density

Almassalha, L. M., Bauer, G. M., Wu, W., Cherkezyan, L., Zhang, D., Kendra, A., Gladstein, S., Chandler, J. E., Vanderway, D., Seagle, B. L. L., Ugolkov, A., Billadeau, D. D., O'Halloran, T. V., Mazar, A. P., Roy, H. K., Szleifer, I. G., Shahabi, S. & Backman, V., Nov 1 2017, In : Nature Biomedical Engineering. 1, 11, p. 902-913 12 p.

Research output: Contribution to journalArticle

Chromatin
Modulation
Genes
Cells
Gene expression
27 Citations (Scopus)

Molecular pathways: Revisiting glycogen synthase kinase-3β as a target for the treatment of cancer

Walz, A. L., Ugolkov, A., Chandra, S., Kozikowski, A., Carneiro Filho, B. A., O'Halloran, T. V., Giles, F. J., Billadeau, D. D. & Mazar, A. P., Apr 15 2017, In : Clinical Cancer Research. 23, 8, p. 1891-1897 7 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Neoplasms
Protein-Serine-Threonine Kinases
Cell Nucleus
Type 2 Diabetes Mellitus
2 Citations (Scopus)
Caenorhabditis elegans
Embryonic Development
Zinc
Availability
Oocytes
17 Citations (Scopus)

Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy

Que, E. L., Duncan, F. E., Bayer, A. R., Philips, S. J., Roth, E. W., Bleher, R., Gleber, S. C., Vogt, S., Woodruff, T. K. & O'Halloran, T. V., Feb 1 2017, In : Integrative Biology (United Kingdom). 9, 2, p. 135-144 10 p.

Research output: Contribution to journalArticle

Zona Pellucida
Electric sparks
Ovum
Zinc
Hardening
2016
19 Citations (Scopus)

Evolution of a heavy metal homeostasis/resistance island reflects increasing copper stress in enterobacteria

Staehlin, B. M., Gibbons, J. G., Rokas, A., O'Halloran, T. V. & Slot, J. C., Jan 1 2016, In : Genome biology and evolution. 8, 3, p. 811-826 16 p.

Research output: Contribution to journalArticle

homeostasis
Enterobacteriaceae
Heavy Metals
Islands
Copper
15 Citations (Scopus)

GSK-3 inhibition overcomes chemoresistance in human breast cancer

Ugolkov, A., Gaisina, I., Zhang, J. S., Billadeau, D. D., White, K., Kozikowski, A., Jain, S., Cristofanilli, M., Giles, F., O'Halloran, T., Cryns, V. L. & Mazar, A. P., Oct 1 2016, In : Cancer Letters. 380, 2, p. 384-392 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
irinotecan
Breast Neoplasms
Therapeutics
Protein-Serine-Threonine Kinases
4 Citations (Scopus)

Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer

Upreti, M., Jyoti, A., Johnson, S. E., Swindell, E. P., Napier, D., Sethi, P., Chan, R., Feddock, J. M., Weiss, H. L., O'Halloran, T. V. & Evers, B. M., Jul 5 2016, In : Oncotarget. 7, 27, p. 41559-41574 16 p.

Research output: Contribution to journalArticle

Galectin 1
Triple Negative Breast Neoplasms
Radiation
Neoplasms
Therapeutics
16 Citations (Scopus)
Fertilization
Zinc
Embryonic Structures
Biomarkers
Zygote
27 Citations (Scopus)

The zinc spark is an inorganic signature of human egg activation

Duncan, F. E., Que, E. L., Zhang, N., Feinberg, E. C., O'Halloran, T. V. & Woodruff, T. K., Apr 26 2016, In : Scientific Reports. 6, 24737.

Research output: Contribution to journalArticle

Ovum
Zinc
Ionomycin
Calcium
Germ Cells
2015
15 Citations (Scopus)

3D tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and radiation

Sethi, P., Jyoti, A., Swindell, E. P., Chan, R., Langner, U. W., Feddock, J. M., Nagarajan, R., O'Halloran, T. V. & Upreti, M., Nov 1 2015, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 11, 8, p. 2013-2023 11 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Chemotherapy
Tumors
Radiation
Tissue
48 Citations (Scopus)

Allosteric transcriptional regulation via changes in the overall topology of the core promoter

Philips, S. J., Canalizo-Hernandez, M., Yildirim, I., Schatz, G. C., Mondragon, A. & O'Halloran, T. V., Aug 21 2015, In : Science. 349, 6250, p. 877-881 5 p.

Research output: Contribution to journalArticle

Allosteric Regulation
DNA
DNA-Directed RNA Polymerases
Proteins
A-Form DNA
14 Citations (Scopus)

Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors

Beauchamp, E. M., Kosciuczuk, E. M., Serrano, R., Nanavati, D., Swindell, E. P., Viollet, B., O'Halloran, T. V., Altman, J. K. & Platanias, L. C., Jan 1 2015, In : Molecular cancer therapeutics. 14, 1, p. 202-212 11 p.

Research output: Contribution to journalArticle

Cohort Effect
AMP-Activated Protein Kinases
Acute Myeloid Leukemia
Arsenic
Antineoplastic Agents
34 Citations (Scopus)

Patient-derived tumor xenografts are susceptible to formation of human lymphocytic tumors

Bondarenko, G., Ugolkov, A., Rohan, S., Kulesza, P., Dubrovskyi, O., Gursel, D., Mathews, J., O'Halloran, T. V., Wei, J. J. & Mazar, A. P., Jan 1 2015, In : Neoplasia. 17, 9, p. 735-741 7 p.

Research output: Contribution to journalArticle

Heterografts
Neoplasms
B-Lymphocytes
Pancreatic Neoplasms
Adenocarcinoma
75 Citations (Scopus)

Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

Que, E. L., Bleher, R., Duncan, F. E., Kong, B. Y., Gleber, S. C., Vogt, S., Chen, S., Garwin, S. A., Bayer, A. R., Dravid, V. P., Woodruff, T. K. & O'Halloran, T. V., Jan 1 2015, In : Nature chemistry. 7, 2, p. 130-139 10 p.

Research output: Contribution to journalArticle

Electric sparks
Zinc
Fluxes
Fluorescence microscopy
Tomography
11 Citations (Scopus)

The inorganic anatomy of the mammalian preimplantation embryo and the requirement of zinc during the first mitotic divisions

Kong, B. Y., Duncan, F. E., Que, E. L., Xu, Y., Vogt, S., O'Halloran, T. V. & Woodruff, T. K., Aug 1 2015, In : Developmental Dynamics. 244, 8, p. 935-947 13 p.

Research output: Contribution to journalArticle

Mammalian Embryo
Blastocyst
Zinc
Anatomy
ethylenediamine
2014
5 Citations (Scopus)

Alignment of low-dose X-ray fluorescence tomography images using differential phase contrast

Hong, Y. P., Gleber, S. C., O'Halloran, T. V., Que, E. L., Bleher, R., Vogt, S., Woodruff, T. K. & Jacobsen, C., Jan 1 2014, In : Journal of Synchrotron Radiation. 21, 1, p. 229-234 6 p.

Research output: Contribution to journalArticle

phase contrast
Dosimetry
Tomography
tomography
Pixels
20 Citations (Scopus)

Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM)

Xu, X., Cai, Y., Wei, Y., Donate, F., Juarez, J., Parry, G., Chen, L., Meehan, E. J., Ahn, R. W., Ugolkov, A., Dubrovskyi, O., O'Halloran, T. V., Huang, M. & Mazar, A. P., Jan 21 2014, In : PloS one. 9, 1, e85349.

Research output: Contribution to journalArticle

Urokinase Plasminogen Activator Receptors
u-plasminogen activator
integrins
Integrins
epitopes
30 Citations (Scopus)

Maternally-derived zinc transporters ZIP6 and ZIP10 drive the mammalian oocyte-to-egg transition

Kong, B. Y., Duncan, F. E., Que, E. L., Kim, A. M., O'Halloran, T. V. & Woodruff, T. K., Jan 1 2014, In : Molecular Human Reproduction. 20, 11, p. 1077-1089 13 p., gau066.

Research output: Contribution to journalArticle

Oocytes
Ovum
Zinc
Metals
Cytoplasmic Structures
43 Citations (Scopus)

Structural and Mechanistic Basis of Zinc Regulation Across the E. coli Zur Regulon

Gilston, B. A., Wang, S., Marcus, M. D., Canalizo-Hernández, M. A., Swindell, E. P., Xue, Y., Mondragon, A. & O'Halloran, T. V., Jan 1 2014, In : PLoS biology. 12, 11

Research output: Contribution to journalArticle

Regulon
regulon
Escherichia coli
Zinc
zinc
2013
13 Citations (Scopus)

A copper hyperaccumulation phenotype correlates with pathogenesis in Cryptococcus neoformans

Raja, M. R., Waterman, S. R., Qiu, J., Bleher, R., Williamson, P. R. & O'Halloran, T. V., Apr 1 2013, In : Metallomics. 5, 4, p. 363-371 9 p.

Research output: Contribution to journalArticle

Cryptococcus neoformans
Copper
Phenotype
Pathogens
Virulence
43 Citations (Scopus)

Anticancer activity of small-molecule and nanoparticulate arsenic(III) complexes

Swindell, E. P., Hankins, P. L., Chen, H., Miodragović, C. D. S. U. & O'Halloran, T. V., Nov 4 2013, In : Inorganic Chemistry. 52, 21, p. 12292-12304 13 p.

Research output: Contribution to journalArticle

arsenic compounds
Arsenic
arsenic
Arsenicals
leukemias
88 Citations (Scopus)

A physical sciences network characterization of non-tumorigenic and metastatic cells

Agus, D. B., Alexander, J. F., Arap, W., Ashili, S., Aslan, J. E., Austin, R. H., Backman, V., Bethel, K. J., Bonneau, R., Chen, W. C., Chen-Tanyolac, C., Choi, N. C., Curley, S. A., Dallas, M., Damania, D., Davies, P. C. W., Decuzzi, P., Dickinson, L., Estevez-Salmeron, L., Estrella, V. & 75 others, Ferrari, M., Fischbach, C., Foo, J., Fraley, S. I., Frantz, C., Fuhrmann, A., Gascard, P., Gatenby, R. A., Geng, Y., Gerecht, S., Gillies, R. J., Godin, B., Grady, W. M., Greenfield, A., Hemphill, C., Hempstead, B. L., Hielscher, A., Hillis, W. D., Holland, E. C., Ibrahim-Hashim, A., Jacks, T., Johnson, R. H., Joo, A., Katz, J. E., Kelbauskas, L., Kesselman, C., King, M. R., Konstantopoulos, K., Kraning-Rush, C. M., Kuhn, P., Kung, K., Kwee, B., Lakins, J. N., Lambert, G., Liao, D., Licht, J. D., Liphardt, J. T., Liu, L., Lloyd, M. C., Lyubimova, A., Mallick, P., Marko, J. F., McCarty, O. J. T., Meldrum, D. R., Michor, F., Mumenthaler, S. M., Nandakumar, V., O'Halloran, T. V., Oh, S., Pasqualini, R., Paszek, M. J., Philips, K. G., Poultney, C. S., Rana, K., Reinhart-King, C. A., Ros, R., Semenza, G. L., Senechal, P., Shuler, M. L., Srinivasan, S., Staunton, J. R., Stypula, Y., Subramanian, H., Tlsty, T. D., Tormoen, G. W., Tseng, Y., Van Oudenaarden, A., Verbridge, S. S., Wan, J. C., Weaver, V. M., Widom, J., Will, C., Wirtz, D., Wojtkowiak, J. & Wu, P. H., Jul 4 2013, In : Scientific reports. 3, 1449.

Research output: Contribution to journalArticle

Natural Science Disciplines
Neoplasm Metastasis
Cell Line
Mechanics
Proteomics
22 Citations (Scopus)

Imaging and elemental mapping of biological specimens with a dual-EDS dedicated scanning transmission electron microscope

Wu, J. S., Kim, A. M., Bleher, R., Myers, B. D., Marvin, R. G., Inada, H., Nakamura, K., Zhang, X. F., Roth, E., Li, S. Y., Woodruff, T. K., O'Halloran, T. V. & Dravid, V. P., May 1 2013, In : Ultramicroscopy. 128, p. 24-31 8 p.

Research output: Contribution to journalArticle

Energy dispersive spectroscopy
Electron microscopes
electron microscopes
Scanning
Imaging techniques
40 Citations (Scopus)

Nano-Encapsulation of Arsenic Trioxide Enhances Efficacy against Murine Lymphoma Model while Minimizing Its Impact on Ovarian Reserve In Vitro and In Vivo

Ahn, R. W., Barrett, S. L., Raja, M. R., Jozefik, J. K., Spaho, L., Chen, H., Bally, M. B., Mazar, A. P., Avram, M. J., Winter, J. N., Gordon, L. I., Shea, L. D., O'Halloran, T. V. & Woodruff, T. K., Mar 20 2013, In : PloS one. 8, 3, e58491.

Research output: Contribution to journalArticle

encapsulation
arsenic
lymphoma
Encapsulation
Lymphoma
9 Citations (Scopus)

PH-responsive theranostic polymer-caged nanobins: Enhanced cytotoxicity and T1 MRI contrast by Her2 targeting

Hong, B. J., Swindell, E. P., Macrenaris, K. W., Hankins, P. L., Chipre, A. J., Mastarone, D. J., Ahn, R. W., Meade, T. J., O'Halloran, T. V. & Nguyen, S., Sep 1 2013, In : Particle and Particle Systems Characterization. 30, 9, p. 770-774 5 p.

Research output: Contribution to journalArticle

Magnetic resonance
Cytotoxicity
magnetic resonance
Polymers
Imaging techniques
9 Citations (Scopus)

Rapid and accurate analysis of an x-ray fluorescence microscopy data set through gaussian mixture-based soft clustering methods

Ward, J., Marvin, R., O'Halloran, T. V., Jacobsen, C. & Vogt, S., Oct 1 2013, In : Microscopy and Microanalysis. 19, 5, p. 1281-1289 9 p.

Research output: Contribution to journalArticle

x ray fluorescence
Fluorescence microscopy
microscopy
parasites
X rays
21 Citations (Scopus)

Robust structure and reactivity of aqueous arsenous acid-platinum(II) anticancer complexes

Miodragovic̈, D. U., Quentzel, J. A., Kurutz, J. W., Stern, C. L., Ahn, R. W., Kandela, I., Mazar, A. & O'Halloran, T. V., Oct 4 2013, In : Angewandte Chemie - International Edition. 52, 41, p. 10749-10752 4 p.

Research output: Contribution to journalArticle

Arsenic
Cytotoxicity
Platinum
Substitution reactions
Ligands
22 Citations (Scopus)

Urokinase plasminogen activator system-Targeted delivery of nanobins as a novel ovarian cancer therapy

Zhang, Y., Kenny, H. A., Swindell, E. P., Mitra, A. K., Hankins, P. L., Ahn, R. W., Gwin, K., Mazar, A. P., O'Halloran, T. V. & Lengyel, E., Dec 1 2013, In : Molecular Cancer Therapeutics. 12, 12, p. 2628-2639 12 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Urokinase-Type Plasminogen Activator
Ovarian Neoplasms
Neoplasms
Therapeutics
2012
35 Citations (Scopus)

Accumulation of cadmium in insulin-producing β cells

El Muayed, M., Raja, M. R., Zhang, X., Macrenaris, K. W., Bhatt, S., Chen, X., Urbanek, M., O'Halloran, T. V. & Lowe Jr, W. L., Nov 1 2012, In : Islets. 4, 6, p. 405-416 12 p.

Research output: Contribution to journalArticle

Cadmium
Insulin
Oxidative Stress
Cadmium Chloride
Type 2 Diabetes Mellitus
47 Citations (Scopus)

A Zinc-Dependent Mechanism Regulates Meiotic Progression in Mammalian Oocytes

Bernhardt, M. L., Kong, B. Y., Kim, A. M., O'Halloran, T. V. & Woodruff, T. K., Apr 1 2012, In : Biology of Reproduction. 86, 4, 114.

Research output: Contribution to journalArticle

Oocytes
Zinc
Proto-Oncogene Proteins c-mos
Metaphase
Telophase

Elucidating the Role of Zinc in Malaria with Synchrotron-Based X-Ray Fluorescence Microscopy and Spectroscopy

Ward, J., Marvin, R., Vogt, S., O'Halloran, T. V. & Penner-Hahn, J., Jan 1 2012, In : Microscopy and Microanalysis. 18, p. 222-223 2 p.

Research output: Contribution to journalArticle

Fluorescence microscopy
Fluorescence spectroscopy
X ray spectroscopy
Synchrotrons
synchrotrons
19 Citations (Scopus)

Fluxes in "free" and total zinc are essential for progression of intraerythrocytic stages of plasmodium falciparum

Marvin, R. G., Wolford, J. L., Kidd, M. J., Murphy, S., Ward, J., Que, E. L., Mayer, M. L., Penner-Hahn, J. E., Haldar, K. & O'Halloran, T. V., Jun 22 2012, In : Chemistry and Biology. 19, 6, p. 731-741 11 p.

Research output: Contribution to journalArticle

Plasmodium falciparum
Zinc
Fluxes
Parasites
Cell signaling
9 Citations (Scopus)

Improved anti-proliferative effect of doxorubicin-containing polymer nanoparticles upon surface modification with cationic groups

Krovi, S. A., Swindell, E. P., O'Halloran, T. V. & Nguyen, S., Dec 28 2012, In : Journal of Materials Chemistry. 22, 48, p. 25463-25470 8 p.

Research output: Contribution to journalArticle

Doxorubicin
Surface treatment
Polymers
Nanoparticles
Control surfaces
35 Citations (Scopus)

Role of CTR4 in the virulence of cryptococcus neoformans

Waterman, S. R., Park, Y. D., Raja, M., Qiu, J., Hammoud, D. A., O'Halloran, T. V. & Williamson, P. R., Nov 9 2012, In : mBio. 3, 5

Research output: Contribution to journalArticle

Cryptococcus neoformans
Virulence
Copper
Metals
Macrophages
29 Citations (Scopus)

Zinc maintains prophase i arrest in mouse oocytes through regulation of the: Mos-mapk pathway

Kong, B. Y., Bernhardt, M. L., Kim, A. M., O'Halloran, T. V. & Woodruff, T. K., Jul 1 2012, In : Biology of reproduction. 87, 1, 1 p.

Research output: Contribution to journalArticle

Prophase
ethylenediamine
Meiotic Prophase I
Oocytes
Zinc
2011
7 Citations (Scopus)

Design, Implementation, Simulation, and Visualization of a Highly Efficient RIM Microfluidic Mixer for Rapid Freeze-Quench of Biological Samples

Schmidt, B., Mahmud, G., Soh, S., Kim, S. H., Page, T., O'Halloran, T. V., Grzybowski, B. A. & Hoffman, B. M., Aug 1 2011, In : Applied Magnetic Resonance. 40, 4, p. 415-425 11 p.

Research output: Contribution to journalArticle

simulation
reaction intermediates
injection molding
low Reynolds number
wheels
21 Citations (Scopus)

Development and modeling of arsenic-trioxide-loaded thermosensitive liposomes for anticancer drug delivery

Winter, N. D., Murphy, R. K. J., O'Halloran, T. V. & Schatz, G. C., Jun 1 2011, In : Journal of Liposome Research. 21, 2, p. 106-115 10 p.

Research output: Contribution to journalArticle

Liposomes
Arsenic
Pharmaceutical Preparations
Permeability
Gels
19 Citations (Scopus)

High-throughput screen for identifying small molecules that target fungal zinc homeostasis

Simm, C., Luan, C-H., Weiss, E. L. & O'Halloran, T. V., Sep 29 2011, In : PloS one. 6, 9, e25136.

Research output: Contribution to journalArticle

Zinc
homeostasis
Homeostasis
zinc
Throughput
36 Citations (Scopus)
Polymers
drugs
polymers
Drug delivery
Pharmaceutical Preparations
51 Citations (Scopus)

Zinc requirement during meiosis I-meiosis II transition in mouse oocytes is independent of the MOS-MAPK pathway

Bernhardt, M. L., Kim, A. M., O'Halloran, T. V. & Woodruff, T. K., Mar 1 2011, In : Biology of Reproduction. 84, 3, p. 526-536 11 p.

Research output: Contribution to journalArticle

Meiosis
Oocytes
Zinc
ethylenediamine
Maturation-Promoting Factor
98 Citations (Scopus)

Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs

Kim, A. M., Bernhardt, M. L., Kong, B. Y., Ahn, R. W., Vogt, S., Woodruff, T. K. & O'Halloran, T. V., Jul 15 2011, In : ACS Chemical Biology. 6, 7, p. 716-723 8 p.

Research output: Contribution to journalArticle

Electric sparks
Fertilization
Eggs
Zinc
Cell Cycle
2010
36 Citations (Scopus)

Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic β-cell function

El Muayed, M., Billings, L. K., Raja, M. R., Zhang, X., Park, P. J., Newman, M. V., Kaufman, D. B., O'Halloran, T. V. & Lowe Jr, W. L., Aug 1 2010, In : Journal of Endocrinology. 206, 2, p. 159-169 11 p.

Research output: Contribution to journalArticle

Down-Regulation
Cytokines
Interleukin-1
Insulin
Messenger RNA