• 17497 Citations
1978 …2022
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Research Output 1978 2019

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Review article
2013
24 Citations (Scopus)

The many spaces of uPAR: Delivery of theranostic agents and nanobins to multiple tumor compartments through a single target

O'Halloran, T. V., Ahn, R., Hankins, P., Swindell, E. & Mazar, A. P., Sep 3 2013, In : Theranostics. 3, 7, p. 496-506 11 p.

Research output: Contribution to journalReview article

Plasminogen Activators
Urokinase-Type Plasminogen Activator
Neoplasms
Theranostic Nanomedicine
Monoclonal Antibodies
18 Citations (Scopus)

Zinc, insulin, and the liver: A ménage à trois

O'Halloran, T. V., Kebede, M., Philips, S. J. & Attie, A. D., Oct 1 2013, In : Journal of Clinical Investigation. 123, 10, p. 4136-4139 4 p.

Research output: Contribution to journalReview article

Zinc
Insulin
Liver
Insulysin
Secretory Vesicles
2011
40 Citations (Scopus)

Development of novel therapeutics targeting the urokinase plasminogen activator receptor (uPAR) and their translation toward the clinic

Mazar, A. P., Ahn, R. W. & O'Halloran, T. V., Jun 1 2011, In : Current Pharmaceutical Design. 17, 19, p. 1970-1978 9 p.

Research output: Contribution to journalReview article

Urokinase Plasminogen Activator Receptors
Therapeutics
Plasminogen Activators
Urokinase-Type Plasminogen Activator
Neoplasms
2006
313 Citations (Scopus)

Activation of superoxide dismutases: Putting the metal to the pedal

Culotta, V. C., Yang, M. & O'Halloran, T. V., Jul 1 2006, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1763, 7, p. 747-758 12 p.

Research output: Contribution to journalReview article

Superoxide Dismutase
Foot
Copper
Metals
Manganese
89 Citations (Scopus)

Posttranslational modifications in Cu,Zn-superoxide dismutase and mutations associated with amyptrophic lateral sclerosis

Furukawa, Y. & O'Halloran, T. V., May 1 2006, In : Antioxidants and Redox Signaling. 8, 5-6, p. 847-867 21 p.

Research output: Contribution to journalReview article

Motor Neuron Disease
Post Translational Protein Processing
Copper
Disulfides
Mutation
2003
801 Citations (Scopus)

Transition metal speciation in the cell: Insights from the chemistry of metal ion receptors

Finney, L. A. & O'Halloran, T. V., May 9 2003, In : Science. 300, 5621, p. 931-936 6 p.

Research output: Contribution to journalReview article

Metals
Ions
Metallochaperones
Inorganic Chemistry
Proteins
2001
376 Citations (Scopus)

Function, structure, and mechanism of intracellular copper trafficking proteins

Huffman, D. L. & O'Halloran, T. V., Jul 30 2001, In : Annual Review of Biochemistry. 70, p. 677-701 25 p.

Research output: Contribution to journalReview article

Protein Transport
Copper
Metals
Proteins
Chemical activation
2000
148 Citations (Scopus)

Structure and chemistry of the copper chaperone proteins

Rosenzweig, A. C. & O'Halloran, T. V., Apr 1 2000, In : Current Opinion in Chemical Biology. 4, 2, p. 140-147 8 p.

Research output: Contribution to journalReview article

Copper
Proteins
1996
22 Citations (Scopus)

Metal-responsive gene regulation and the zinc metalloregulatory model.

Suhy, D. A. & O'Halloran, T. V., Jan 1 1996, In : Metal Ions in Biological Systems. 32, p. 557-578 22 p.

Research output: Contribution to journalReview article

Post Transcriptional RNA Processing
Gene expression regulation
Apoproteins
Metallothionein
Zinc Fingers
1993
516 Citations (Scopus)

Transition metals in control of gene expression

O'Halloran, T. V., Jan 1 1993, In : Science. 261, 5122, p. 715-725 11 p.

Research output: Contribution to journalReview article

Metals
Gene Expression
Mercury
Inorganic Chemistry
Iron