Grants per year
Personal profile
Research Interests
Dr. Kume’s research interests focus on cardiovascular development, cardiovascular stem/progenitor cells, and angiogenesis. Current studies include the role of Foxc transcription factors in cardiovascular development and disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular Biology, PhD, University of Tokyo
… → 1996
Research interests keywords
- Cardiovascular Diseases
- Cardiovascular System
- Developmental Biology
- Developmental Genetics
- Stem Cells
- Vascular Biology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel ocular imaging and molecular analysis of anterior eye segment for glaucoma
Kume, T., Kume, T., Zhang, H. F., Zhang, H. F. & Tan, C.
3/1/23 → 2/29/28
Project: Research project
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Administrative Supplement to Encourage Research in Valvular Heart Disease (CAROL Act),
National Heart, Lung, and Blood Institute
4/1/22 → 3/31/26
Project: Research project
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New roles of endothelial regrowth in ischemic tissue recovery and regeneration
National Heart, Lung, and Blood Institute
4/1/22 → 3/31/26
Project: Research project
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The identification and pathophysiology of non-infarcted but injured myocardium in the post-ischemic heart
Arora, R. K., Arora, R. K., Zhao, M., Zhao, M., Arora, R. K., Jin, J., Jin, J., Kume, T., Kume, T., Kwasny, M. J., Kwasny, M. J., Lomasney, J. W. & Lomasney, J. W.
National Heart, Lung, and Blood Institute
1/1/21 → 12/31/24
Project: Research project
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Molecular mechanisms of Foxc-mediated angiogenesis
National Heart, Lung, and Blood Institute
7/1/18 → 6/30/23
Project: Research project
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Differential roles of FOXC2 in the trabecular meshwork and Schlemm’s canal in glaucomatous pathology
Ujiie, N., Norden, P. R., Fang, R., Beckmann, L., Cai, Z., Kweon, J., Liu, T., Tan, C., Kuhn, M. S., Stamer, W. D., Aoto, K., Quaggin, S. E., Zhang, H. F. & Kume, T., Sep 2023, In: Life science alliance. 9, e202201721.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: Lymphatic system: organ specific functions in health and disease
Koltowska, K., Jakus, Z., Hong, Y. K. & Kume, T., 2023, In: Frontiers in Cell and Developmental Biology. 11, 1224584.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia–reperfusion injury
Tan, C., Norden, P. R., Yu, W., Liu, T., Ujiie, N., Lee, S. K., Yan, X., Dyakiv, Y., Aoto, K., Ortega, S., De Plaen, I. G., Sampath, V. & Kume, T., Jul 5 2023, In: EMBO Reports. 24, 7, e56030.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
FoxC1 activates limbal epithelial stem cells following corneal epithelial debridement
Yang, W., Lee, S. K., Lehmann, O. J., Wu, Z., Hiriyanna, S., Swaroop, A., Lavker, R. M., Peng, H. & Kume, T., Sep 2023, In: Experimental eye research. 234, 109599.Research output: Contribution to journal › Article › peer-review
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Foxc1 and Foxc2 are indispensable for the maintenance of nephron and stromal progenitors in the developing kidney
Motojima, M., Tanaka, M. & Kume, T., Oct 2022, In: Journal of cell science. 135, 19, jcs260356.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Supplementary Material for: Characterization of Kidney and Skeleton Phenotypes of Mice Double Heterozygous for Foxc1 and Foxc2
Motojima, M. (Creator), Tanimoto, S. (Creator), Ohtsuka, M. (Creator), Matsusaka, T. (Creator), Kume, T. (Creator) & Abe, K. (Creator), Karger Publishers, 2016
DOI: 10.6084/m9.figshare.5129671, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Characterization_of_Kidney_and_Skeleton_Phenotypes_of_Mice_Double_Heterozygous_for_Foxc1_and_Foxc2/5129671
Dataset