Grants per year
Personal profile
Research Interests
Dr. Kume’s research interests focus on cardiovascular development, cardiovascular stem/progenitor cells, and angiogenesis. Current studies include the role of Foxc transcription factors in cardiovascular development and disease.
Education/Academic qualification
PhD, The University of Tokyo
… → 1996
Research interests
- Cardiovascular Diseases
- Cardiovascular System
- Developmental Biology
- Developmental Genetics
- Stem Cells
- Vascular Biology
Fingerprint
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants
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Molecular mechanisms of Foxc-mediated angiogenesis
National Heart, Lung, and Blood Institute
7/1/18 → 6/30/22
Project: Research project
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Mechanisms underlying the formation of the cornea and ocular surface epithelium
Kennedy Institute - National Eye Clinic
5/1/18 → 4/30/22
Project: Research project
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A-006 Potential Treatment of Corneal Vascularization
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/21
Project: Research project
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Fox Transcription factors in lymphatic vessel development
National Heart, Lung, and Blood Institute
9/1/15 → 6/30/20
Project: Research project
Research Output
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A temporo-spatial regulation of sema3c is essential for interaction of progenitor cells during cardiac outflow tract development
Kodo, K., Shibata, S., Miyagawa-Tomita, S., Ong, S. G., Takahashi, H., Kume, T., Okano, H., Matsuoka, R. & Yamagishi, H., Jan 1 2020, Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension. Springer Singapore, p. 377-379 3 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access -
Conditional inactivation of Foxc1 and Foxc2 in neural crest cells leads to cardiac abnormalities
Sanchez, J., Miyake, R., Cheng, A., Liu, T., Iseki, S. & Kume, T., Jul 1 2020, In: Genesis. 58, 7, e23364.Research output: Contribution to journal › Letter › peer-review
1 Scopus citations -
In vivo imaging of Schlemm’s canal and limbal vascular network in mouse using visible-light OCT
Zhang, X., Beckmann, L., Miller, D. A., Shao, G., Cai, Z., Sun, C., Sheibani, N., Liu, X., Schuman, J., Johnson, M., Kume, T. & Zhang, H. F., Feb 2020, In: Investigative Ophthalmology and Visual Science. 61, 2, 2761682.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation
Norden, P. R., Sabine, A., Wang, Y., Demir, C. S., Liu, T., Petrova, T. V. & Kume, T., Jun 2020, In: eLife. 9, p. 1-35 35 p., e53814.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
The Role of Lymphatic Vascular Function in Metabolic Disorders
Norden, P. R. & Kume, T., May 5 2020, In: Frontiers in Physiology. 11, 404.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations