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Tsutomu Kume

  • 4135 Citations
1992 …2020

Research output per year

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Personal profile

Research Interests

Dr. Kume’s research interests focus on cardiovascular development, cardiovascular stem/progenitor cells, and angiogenesis. Current studies include the role of Foxc transcription factors in cardiovascular development and disease.

Education/Academic qualification

PhD, University of Tokyo

… → 1996

Research interests

  • Cardiovascular Diseases
  • Cardiovascular System
  • Developmental Biology
  • Developmental Genetics
  • Stem Cells
  • Vascular Biology

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Grants

Molecular mechanisms of Foxc-mediated angiogenesis

Kume, T.

National Heart, Lung, and Blood Institute

7/1/18 → 6/30/22

Project: Research project

    • Mechanisms underlying the formation of the cornea and ocular surface epithelium

    Kume, T.

    Kennedy Institute - National Eye Clinic

    5/1/18 → 4/30/22

    Project: Research project

    • A-006 Potential Treatment of Corneal Vascularization

    Kume, T.

    Searle Funds at The Chicago Community Trust

    1/1/17 → 12/31/21

    Project: Research project

    Fox Transcription factors in lymphatic vessel development

    Kume, T.

    National Heart, Lung, and Blood Institute

    9/1/15 → 6/30/20

    Project: Research project

    • Predoctoral-Erin Lambers: The Role of Foxc1 During the Differentiation of Embryonic Stem Cells into Functional Cardiomyocytes

    Kume, T.

    American Heart Association Midwest Affiliate

    7/1/15 → 6/30/17

    Project: Research project

    • Research Output

    Conditional inactivation of Foxc1 and Foxc2 in neural crest cells leads to cardiac abnormalities

    Sanchez, J., Miyake, R., Cheng, A., Liu, T., Iseki, S. & Kume, T., Jan 1 2020, (Accepted/In press) In : Genesis.

    Research output: Contribution to journal › Letter

    • In vivo imaging of Schlemm’s canal and limbal vascular network in mouse using visible-light OCT

    Zhang, X., Beckmann, L., Miller, D. A., Shao, G., Cai, Z., Sun, C., Sheibani, N., Liu, X., Schuman, J., Johnson, M., Kume, T. & Zhang, H. F., Feb 2020, In : Investigative Ophthalmology and Visual Science. 61, 2, 2761682.

    Research output: Contribution to journal › Article

    Open Access

    • The Role of Lymphatic Vascular Function in Metabolic Disorders

    Norden, P. R. & Kume, T., May 5 2020, In : Frontiers in Physiology. 11, 404.

    Research output: Contribution to journal › Review article

    Open Access

    • Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis

    Welsh, J. D., Hoofnagle, M. H., Bamezai, S., Oxendine, M., Lim, L., Hall, J. D., Yang, J., Schultz, S., Engel, J. D., Kume, T., Oliver, G., Jimenez, J. M. & Kahn, M. L., Dec 2 2019, In : Journal of Clinical Investigation. 129, 12, p. 5489-5500 12 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Organ/tissue-specific vascular endothelial cell heterogeneity in health and disease

    Minami, T., Muramatsu, M. & Kume, T., Jan 1 2019, In : Biological and Pharmaceutical Bulletin. 42, 10, p. 1609-1619 11 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations