Grants per year
Personal profile
Research Interests
Dr. Kume’s research interests focus on cardiovascular development, cardiovascular stem/progenitor cells, and angiogenesis. Current studies include the role of Foxc transcription factors in cardiovascular development and disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular Biology, PhD, University of Tokyo
… → 1996
Research interests
- Cardiovascular Diseases
- Cardiovascular System
- Developmental Biology
- Developmental Genetics
- Stem Cells
- Vascular Biology
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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New roles of endothelial regrowth in ischemic tissue recovery and regeneration
National Heart, Lung, and Blood Institute
4/1/22 → 3/31/26
Project: Research project
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Molecular mechanisms of Foxc-mediated angiogenesis
National Heart, Lung, and Blood Institute
7/1/18 → 6/30/23
Project: Research project
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Mechanisms underlying the formation of the cornea and ocular surface epithelium
5/1/18 → 4/30/23
Project: Research project
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A-006 Potential Treatment of Corneal Vascularization
Searle Funds at The Chicago Community Trust
1/1/17 → 12/31/23
Project: Research project
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Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development
Takenoshita, M., Takechi, M., Vu Hoang, T., Furutera, T., Akagawa, C., Namangkalakul, W., Aoto, K., Kume, T., Miyashin, M., Iwamoto, T. & Iseki, S., Aug 2021, In: Developmental Dynamics. 250, 8, p. 1125-1139 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Escape of hair follicle stem cells causes stem cell exhaustion during aging
Zhang, C., Wang, D., Wang, J., Wang, L., Qiu, W., Kume, T., Dowell, R. & Yi, R., Oct 2021, In: Nature Aging. 1, 10, p. 889-903 15 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification
Almubarak, A., Lavy, R., Srnic, N., Hu, Y., Maripuri, D. P., Kume, T. & Berry, F. B., Sep 1 2021, In: Journal of Biological Chemistry. 297, 3, 101020.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular Mechanisms Controlling Lymphatic Endothelial Junction Integrity
Norden, P. R. & Kume, T., Jan 14 2021, In: Frontiers in Cell and Developmental Biology. 8, 627647.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Super-enhancer-associated transcription factors maintain transcriptional regulation in mature podocytes
Yang, J., Zhang, D., Motojima, M., Kume, T., Hou, Q., Pan, Y., Duan, A., Zhang, M., Jiang, S., Hou, J., Shi, J., Qin, Z. & Liu, Z., Jun 2021, In: Journal of the American Society of Nephrology. 32, 6, p. 1323-1337 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Datasets
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Supplementary Material for: Characterization of Kidney and Skeleton Phenotypes of Mice Double Heterozygous for Foxc1 and Foxc2
Motojima, M. (Creator), Tanimoto, S. (Creator), Ohtsuka, M. (Creator), Matsusaka, T. (Creator), Kume, T. (Creator) & Abe, K. (Creator), Karger Publishers, 2016
DOI: 10.6084/m9.figshare.5129671.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Characterization_of_Kidney_and_Skeleton_Phenotypes_of_Mice_Double_Heterozygous_for_Foxc1_and_Foxc2/5129671/1
Dataset