• 1560 Citations
20052020

Research output per year

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Research Output

  • 1560 Citations
  • 41 Article
  • 8 Review article
  • 2 Chapter
  • 2 Comment/debate
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Article
2020

Survivorship support in head and neck cancer: American Head and Neck Society survey

Cognetti, D. M., Villaflor, V. M., Fakhry, C., Miller, M. C. & Malloy, K. M., May 1 2020, In : Head and Neck. 42, 5, p. 939-944 6 p.

Research output: Contribution to journalArticle

2019

Association of Tumor Mutational Burden With DNA Repair Mutations and Response to Anti–PD-1/PD-L1 Therapy in Non–Small-Cell Lung Cancer

Chae, Y. K., Davis, A. A., Raparia, K., Agte, S., Pan, A., Mohindra, N., Villaflor, V. & Giles, F., Mar 2019, In : Clinical Lung Cancer. 20, 2, p. 88-96.e6

Research output: Contribution to journalArticle

16 Scopus citations

Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer

Chae, Y. K., Viveiros, P., Lopes, G., Sukhadia, B., Sheikh, M. M., Saravia, D., Florou, V., Sokol, E. S., Frampton, G. M., Chalmers, Z. R., Ali, S. M., Ross, J. S., Chang, S., Wang, S., Chiec, L., Rahbari, A., Mohindra, N., Villaflor, V., Shin, S. H., Oh, M. & 5 others, Anker, J., Park, L. C., Wang, V., Chuang, J. & Park, W., Oct 2019, In : Journal of Thoracic Oncology. 14, 10, p. 1807-1817 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical Implications of Circulating Tumor DNA Tumor Mutational Burden (ctDNA TMB) in Non-Small Cell Lung Cancer

Chae, Y. K., Davis, A. A., Agte, S., Pan, A., Simon, N. I., Iams, W. T., Cruz, M. R., Tamragouri, K., Rhee, K., Mohindra, N., Villaflor, V., Park, W., Lopes, G. & Giles, F. J., Jun 2019, In : Oncologist. 24, 6, p. 820-828 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Optima: A phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer

Seiwert, T. Y., Foster, C. C., Blair, E. A., Karrison, T. G., Agrawal, N., Melotek, J. M., Portugal, L., Brisson, R. J., Dekker, A., Kochanny, S., Gooi, Z., Lingen, M. W., Villaflor, V. M., Ginat, D. T., Haraf, D. J. & Vokes, E. E., Feb 1 2019, In : Annals of Oncology. 30, 2, p. 297-302 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2018

Heuristic value-based framework for lung cancer decision-making

Mambetsariev, I., Pharaon, R., Nam, A., Knopf, K., Djulbegovic, B., Villaflor, V. M., Vokes, E. E. & Salgia, R., Jul 1 2018, In : Oncotarget. 9, 52, p. 29877-29891 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Indoleamine 2,3-dioxygenase 1 and overall survival of patients diagnosed with esophageal cancer

Rosenberg, A. J., Wainwright, D. A., Rademaker, A., Galvez, C., Genet, M., Zhai, L., Lauing, K. L., Mulcahy, M. F., Hayes, J. P., Odell, D. D., Horbinski, C., Komanduri, S., Tetreault, M. P., Kim, K. Y. A. & Villaflor, V. M., May 1 2018, In : Oncotarget. 9, 34, p. 23482-23493 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Inhibition of the fibroblast growth factor receptor (FGFR) pathway: The current landscape and barriers to clinical application

Chae, Y. K., Ranganath, K., Hammerman, P. S., Vaklavas, C., Mohindra, N., Kalyan, A., Matsangou, M., Costa, R., Carneiro, B., Villaflor, V. M., Cristofanilli, M. & Giles, F. J., Jan 1 2017, In : Oncotarget. 8, 9, p. 16052-16074 23 p.

Research output: Contribution to journalArticle

109 Scopus citations

Neoadjuvant Treatment for Locally Invasive Esophageal Cancer

Iams, W. T. & Villaflor, V. M., Jul 1 2017, In : World Journal of Surgery. 41, 7, p. 1719-1725 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Salivary Gland Secretory Carcinoma with High-Grade Transformation, CDKN2A/B Loss, Distant Metastasis, and Lack of Sustained Response to Crizotinib

Cipriani, N. A., Blair, E. A., Finkle, J., Kraninger, J. L., Straus, C. M., Villaflor, V. M. & Ginat, D. T., Oct 1 2017, In : International Journal of Surgical Pathology. 25, 7, p. 613-618 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer

Villaflor, V., Won, B., Nagy, R., Banks, K., Lanman, R. B., Talasaz, A. A. & Salgia, R., Jan 1 2016, In : Oncotarget. 7, 41, p. 66880-66891 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

CALGB 80403 (Alliance)/E1206: A randomized phase II study of three chemotherapy regimens plus cetuximab in metastatic esophageal and gastroesophageal Junction Cancers

Enzinger, P. C., Burtness, B. A., Niedzwiecki, D., Ye, X., Douglas, K., Ilson, D. H., Villaflor, V. M., Cohen, S. J., Mayer, R. J., Venook, A., Benson, A. B. & Goldberg, R. M., Aug 10 2016, In : Journal of Clinical Oncology. 34, 23, p. 2736-2742 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation

Vigneswaran, J., Tan, Y. H. C., Murgu, S. D., Won, B. M., Patton, K. A., Villaflor, V. M., Hoffman, P. C., Hensing, T., Hogarth, D. K., Malik, R., MacMahon, H., Mueller, J., Simon, C. A., Vigneswaran, W. T., Wigfield, C. H., Ferguson, M. K., Husain, A. N., Vokes, E. E. & Salgia, R., 2016, In : Oncotarget. 7, 14, p. 18876-18886 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Final Results of a Randomized Phase 2 Trial Investigating the Addition of Cetuximab to Induction Chemotherapy and Accelerated or Hyperfractionated Chemoradiation for Locoregionally Advanced Head and Neck Cancer

Seiwert, T. Y., Melotek, J. M., Blair, E. A., Stenson, K. M., Salama, J. K., Witt, M. E., Brisson, R. J., Chawla, A., Dekker, A., Lingen, M. W., Kocherginsky, M., Villaflor, V. M., Cohen, E. E. W., Haraf, D. J. & Vokes, E. E., Sep 1 2016, In : International Journal of Radiation Oncology Biology Physics. 96, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Oral Cavity Clear Cell Odontogenic Carcinoma

Ginat, D. T., Villaflor, V. & Cipriani, N. A., Jun 1 2016, In : Head and Neck Pathology. 10, 2, p. 217-220 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer

Villaflor, V. M., Melotek, J. M., Karrison, T. G., Brisson, R. J., Blair, E. A., Portugal, L., De Souza, J. A., Ginat, D. T., Stenson, K. M., Langerman, A., Kocherginsky, M., Spiotto, M. T., Hannigan, N., Seiwert, T. Y., Cohen, E. E. W., Vokes, E. E. & Haraf, D. J., May 1 2016, In : Annals of Oncology. 27, 5, p. 908-913 6 p., mdw051.

Research output: Contribution to journalArticle

31 Scopus citations
2015

AXLIs a logical molecular target in headand neck squamous cell carcinoma

Brand, T. M., Iida, M., Stein, A. P., Corrigan, K. L., Braverman, C. M., Coan, J. P., Pearson, H. E., Bahrar, H., Fowler, T. L., Bednarz, B. P., Saha, S., Yang, D., Gill, P. S., Lingen, M. W., Saloura, V., Villaflor, V. M., Salgia, R., Kimple, R. J. & Wheeler, D. L., Jun 1 2015, In : Clinical Cancer Research. 21, 11, p. 2601-2612 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Ex vivo antibody-dependent cellular cytotoxicity inducibility predicts efficacy of cetuximab

Taylor, R. J., Saloura, V., Jain, A., Goloubeva, O., Wong, S., Kronsberg, S., Nagilla, M., Silpino, L., De Souza, J., Seiwert, T., Vokes, E., Villaflor, V. & Cohen, E. E. W., May 2015, In : Cancer Immunology Research. 3, 5, p. 567-574 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Leptomeningeal carcinomatosis in esophageal cancer: A case series and systematic review of the literature

Lukas, R. V., Mata-Machado, N. A., Nicholas, M. K., Salgia, R., Antic, T. & Villaflor, V. M., Nov 1 2015, In : Diseases of the Esophagus. 28, 8, p. 772-781 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer

Cohen, E. E. W., Karrison, T. G., Kocherginsky, M., Mueller, J., Egan, R., Huang, C. H., Brockstein, B. E., Agulnik, M. B., Mittal, B. B., Yunus, F., Samant, S., Raez, L. E., Mehra, R., Kumar, P., Ondrey, F., Marchand, P., Braegas, B., Seiwert, T. Y., Villaflor, V. M., Haraf, D. J. & 1 others, Vokes, E. E., Sep 1 2014, In : Journal of Clinical Oncology. 32, 25, p. 2735-2743 9 p.

Research output: Contribution to journalArticle

257 Scopus citations
2013

A phase I dose escalation study of ad GV.EGR.TNF.11D (TNFeradeTMM Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation

Seiwert, T. Y., Darg, T., Haraf, D., Blair, E. A., Stenson, K., Cohen, E. E. W., Salama, J. K., Villaflor, V., Witt, M. E., Lingen, M. W., Weichselbaum, R. R. & Vokes, E. E., Mar 1 2013, In : Annals of Oncology. 24, 3, p. 769-776 8 p., mds523.

Research output: Contribution to journalArticle

14 Scopus citations

Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers

Hasina, R., Mollberg, N., Kawada, I., Mutreja, K., Kanade, G., Yala, S., Surati, M., Liu, R., Li, X., Zhou, Y., Ferguson, B. D., Nallasura, V., Cohen, K. S., Hyjek, E., Mueller, J., Kanteti, R., El Hashani, E., Kane, D., Shimada, Y., Lingen, M. W. & 9 others, Husain, A. N., Posner, M. C., Waxman, I., Villaflor, V. M., Ferguson, M. K., Varticovski, L., Vokes, E. E., Gill, P. & Salgia, R., Jan 1 2013, In : Cancer Research. 73, 1, p. 184-194 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

O-6-methylguanine-deoxyribonucleic acid methyltransferase methylation enhances response to temozolomide treatment in esophageal cancer

Hasina, R., Surati, M., Kawada, I., Arif, Q., Carey, G., Kanteti, R., Husain, A., Ferguson, M., Vokes, E., Villaflor, V. & Salgia, R., Jan 1 2013, In : Journal of Carcinogenesis. 12, 120632.

Research output: Contribution to journalArticle

11 Scopus citations

Prevalence of off-label use and spending in 2010 among patent-protected chemotherapies in a population-based cohort of medical oncologists

Conti, R. M., Bernstein, A. C., Villaflor, V. M., Schilsky, R. L., Rosenthal, M. B. & Bach, P. B., Mar 20 2013, In : Journal of Clinical Oncology. 31, 9, p. 1134-1139 6 p.

Research output: Contribution to journalArticle

83 Scopus citations

Targeted agents in non-small cell lung cancer therapy: What is there on the horizon?

Villaflor, V. & Salgia, R., Jan 1 2013, In : Journal of Carcinogenesis. 12, 109253.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Chemoradiation for patients with large-volume laryngeal cancers

Stenson, K. M., MacCracken, E., Kunnavakkam, R., Ezra, E. E., Portugal, L. D., Villaflor, V., Seiwert, T., Blair, E., Haraf, D. J., Salama, J. K. & Vokes, E. E., Aug 1 2012, In : Head and Neck. 34, 8, p. 1162-1167 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer

Hasselle, M. D., Haraf, D. J., Rusthoven, K. E., Golden, D. W., Salgia, R., Villaflor, V. M., Shah, N., Hoffman, P. C., Chmura, S. J., Connell, P. P., Vokes, E. E., Weichselbaum, R. R. & Salama, J. K., Jan 1 2012, In : Journal of Thoracic Oncology. 7, 2, p. 376-381 6 p.

Research output: Contribution to journalArticle

75 Scopus citations

Multidisciplinary approach for patients with esophageal cancer

Villaflor, V. M., Allaix, M. E., Minsky, B., Herbella, F. A. & Patti, M. G., Dec 1 2012, In : World Journal of Gastroenterology. 18, 46, p. 6737-6746 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Stereotactic body radiotherapy for multisite extracranial oligometastases: Final report of a dose escalation trial in patients with 1 to 5 sites of metastatic disease

Salama, J. K., Hasselle, M. D., Chmura, S. J., Malik, R., Mehta, N., Yenice, K. M., Villaflor, V. M., Stadler, W. M., Hoffman, P. C., Cohen, E. E. W., Connell, P. P., Haraf, D. J., Vokes, E. E., Hellman, S. & Weichselbaum, R. R., Jun 1 2012, In : Cancer. 118, 11, p. 2962-2970 9 p.

Research output: Contribution to journalArticle

209 Scopus citations
2011

Adjuvant chemoradiotherapy for locoregionally advanced and high-risk salivary gland malignancies

Pederson, A. W., Salama, J. K., Haraf, D. J., Witt, M. E., Stenson, K. M., Portugal, L., Seiwert, T., Villaflor, V. M., Cohen, E. E. W., Vokes, E. E. & Blair, E. A., Jul 28 2011, In : Head and Neck Oncology. 3, 1, 31.

Research output: Contribution to journalArticle

33 Scopus citations

Pathologic response rates following definitive dose image-guided chemoradiotherapy and resection for locally advanced non-small cell lung cancer

Shumway, D., Corbin, K., Salgia, R., Hoffman, P., Villaflor, V., Malik, R. M., Haraf, D. J., Vigneswaren, W. T., Shaikh, A. Y., Connell, P. P., Ferguson, M. K. & Salama, J. K., Dec 1 2011, In : Lung Cancer. 74, 3, p. 446-450 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Personalized treatment of lung cancer

Salgia, R., Hensing, T., Campbell, N., Salama, A. K., Maitland, M., Hoffman, P., Villaflor, V. & Vokes, E. E., Apr 1 2011, In : Seminars in Oncology. 38, 2, p. 274-283 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Phase II trial of pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated patients with squamous cell carcinoma of the head and neck

Villaflor, V. M., Haraf, D., Salama, J. K., Kocherginsky, M., Langerman, A., Gomez-Abuin, G., Beniwal, P., Blair, E. A., Stenson, K. M., Portugal, L., Seiwert, T., Williams, R. D., Dekker, A. J., Witt, M. E., Vokes, E. E. & Cohen, E. E. W., Nov 2011, In : Annals of Oncology. 22, 11, p. 2501-2507 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation

Choe, K. S., Haraf, D. J., Solanki, A., Cohen, E. E. W., Seiwert, T. Y., Stenson, K. M., Blair, E. A., Portugal, L., Villaflor, V. M., Witt, M. E., Vokes, E. E. & Salama, J. K., Oct 15 2011, In : Cancer. 117, 20, p. 4671-4678 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database

Surati, M., Robinson, M., Nandi, S., Faoro, L., Demchuk, C., Rolle, C. E., Kanteti, R., Ferguson, B. D., Hasina, R., Gangadhar, T. C., Salama, A. K., Arif, Q., Kirchner, C., Mendonca, E., Campbell, N., Limvorasak, S., Villaflor, V., Hensing, T. A., Krausz, T., Vokes, E. E. & 4 others, Husain, A. N., Ferguson, M. K., Karrison, T. G. & Salgia, R., Feb 28 2011, In : Journal of Clinical Bioinformatics. 1, 1, 8.

Research output: Contribution to journalArticle

10 Scopus citations

Takotsubo cardiomyopathy in a patient with squamous cell esophageal carcinoma

Schweizer, M. T., Mehta, R., Salgia, R. & Villaflor, V. M., Jul 10 2011, In : Journal of Clinical Oncology. 29, 20

Research output: Contribution to journalArticle

6 Scopus citations
2010

Neoadjuvant treatment of esophageal cancer

Campbell, N. P. & Villaflor, V. M., Aug 14 2010, In : World Journal of Gastroenterology. 16, 30, p. 3793-3803 11 p.

Research output: Contribution to journalArticle

46 Scopus citations
2009

Single-agent versus combination chemotherapy in patients with advanced non-small cell lung cancer and a performance status of 2: Prognostic factors and treatment selection based on two large randomized clinical trials

Lilenbaum, R., Villaflor, V. M., Langer, C., O'Byrne, K., O'Brien, M., Ross, H. J., Socinski, M., Oldham, F. B., Sandilac, L., Singer, J. W. & Bonomi, P., Jul 2009, In : Journal of Thoracic Oncology. 4, 7, p. 869-874 6 p.

Research output: Contribution to journalArticle

56 Scopus citations
2008

The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib

Fidler, M. J., Argiris, A., Patel, J. D., Johnson, D. H., Sandler, A., Villaflor, V. M., Coon IV, J., Buckingham, L., Kaiser, K., Basu, S. & Bonomi, P., Apr 1 2008, In : Clinical Cancer Research. 14, 7, p. 2088-2094 7 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

The prognostic value of chromosome 7 polysomy in non-small cell lung cancer patients treated with gefitinib

Buckingham, L. E., Coon, J. S., Morrison, L. E., Jacobson, K. K. B., Jewell, S. S., Kaiser, K. A., Mauer, A. M., Muzzafar, T., Polowy, C., Basu, S., Gale, M., Villaflor, V. M. & Bonomi, P., May 1 2007, In : Journal of Thoracic Oncology. 2, 5, p. 414-422 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
2005

Other compounds and targets in non-small cell lung cancer

Villaflor, V. & Bonomi, P., Dec 2005, In : Seminars in Oncology. 32, SUPPL. 10, p. 30-36 7 p.

Research output: Contribution to journalArticle

3 Scopus citations