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Research Output 1976 2017

2017
20 Citations (Scopus)

High glucose induces mitochondrial dysfunction in retinal müller cells: Implications for diabetic retinopathy

Tien, T., Zhang, J., Muto, T., Kim, D., Sarthy, V. P. & Roy, S., Jun 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 7, p. 2915-2921 7 p.

Research output: Contribution to journalArticle

Diabetic Retinopathy
Glucose
Cytochromes c
Oxygen Consumption
Apoptosis
2015
3 Citations (Scopus)

Endothelin2 induces expression of genes associated with reactive gliosis in retinal müller cells

Sarthy, V. P., Sawkar, H. & Dudley, V. J., Jan 1 2015, In : Current Eye Research. 40, 11, p. 1181-1184 4 p.

Research output: Contribution to journalArticle

Gliosis
Endothelin B Receptors
Gene Expression
Glial Fibrillary Acidic Protein
Ciliary Neurotrophic Factor
2014
31 Citations (Scopus)
Pericytes
Connexin 43
Gap Junctions
Apoptosis
Glucose
2013

Erratum: Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization (Diabetes (2011) 60 (614-624))

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A., Eladl, M., Sarthy, V., Nussbaum, J., El-Marakby, A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Mar 1 2013, In : Diabetes. 62, 3, 1 p.

Research output: Contribution to journalComment/debate

Arachidonate 12-Lipoxygenase
Retinal Neovascularization
Diabetic Retinopathy
Oxygen
17 Citations (Scopus)

Multimodal photoacoustic ophthalmoscopy in mouse

Song, W., Wei, Q., Feng, L., Sarthy, V. P., Jiao, S., Liu, X. & Zhang, H. F., Jun 1 2013, In : Journal of Biophotonics. 6, 6-7, p. 505-512 8 p.

Research output: Contribution to journalArticle

Ophthalmoscopy
Photoacoustic effect
mice
Green Fluorescent Proteins
Imaging techniques
2011
34 Citations (Scopus)

Ciliary neurotrophic factor induces genes associated with inflammation and gliosis in the retina: A gene profiling study of flow-sorted, müller cells

Xue, W., Cojocaru, R. I., Dudley, V. J., Brooks, M., Swaroop, A. & Sarthy, V. P., May 31 2011, In : PloS one. 6, 5, e20326.

Research output: Contribution to journalArticle

Ciliary Neurotrophic Factor
neurotrophins
Gliosis
retina
Retina
6 Citations (Scopus)

Gene expression changes in retinal Müller (Glial) cells exposed to elevated pressure

Xue, W., Du, P., Lin, S., Dudley, V. J., Hernandez, M. R. & Sarthy, V. P., Aug 1 2011, In : Current eye research. 36, 8, p. 754-767 14 p.

Research output: Contribution to journalArticle

Neuroglia
Gene Expression
Pressure
Genes
Gliosis
57 Citations (Scopus)

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A., Eladl, M., Sarthy, V. P., Nussbaum, J., El-Marakby, A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Feb 1 2011, In : Diabetes. 60, 2, p. 614-624 11 p.

Research output: Contribution to journalArticle

Arachidonate 12-Lipoxygenase
Retinal Neovascularization
Hydroxyeicosatetraenoic Acids
Diabetic Retinopathy
Oxygen
2009
38 Citations (Scopus)

Differential regulation of high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation in müller cells by IL-1β and IL-6

Yego, E. C. K., Vincent, J. A., Sarthy, V. P., Busik, J. V. & Mohr, S., Apr 1 2009, In : Investigative Ophthalmology and Visual Science. 50, 4, p. 1920-1928 9 p.

Research output: Contribution to journalArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Interleukin-1
Interleukin-6
Glucose
Interleukin-1 Receptors
23 Citations (Scopus)

Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network

Loewen, N., Chen, J., Dudley, V. J., Sarthy, V. P. & Mathura, J. R., May 1 2009, In : Experimental eye research. 88, 5, p. 928-937 10 p.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Genes
Organogenesis
Cytoplasm
Retinal Neovascularization
2007
17 Citations (Scopus)

Characterization of green fluorescent protein-expressing retinal cells in CD 44-transgenic mice

Sarthy, V. P., Hoshi, H., Mills, S. & Dudley, V. J., Feb 9 2007, In : Neuroscience. 144, 3, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Transgenic Mice
Amacrine Cells
Retina
Ganglia
22 Citations (Scopus)

Focus on Molecules: Glial fibrillary acidic protein (GFAP)

Sarthy, V. P., Mar 1 2007, In : Experimental eye research. 84, 3, p. 381-382 2 p.

Research output: Contribution to journalShort survey

Molecular Sequence Data
Alexander Disease
Gliosis
Intermediate Filaments
Glial Fibrillary Acidic Protein
165 Citations (Scopus)

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

Yao, D., Taguchi, T., Matsumura, T., Pestell, R., Edelstein, D., Giardino, I., Suske, G., Rabbani, N., Thornalley, P. J., Sarthy, V. P., Hammes, H. P. & Brownlee, M., Oct 19 2007, In : Journal of Biological Chemistry. 282, 42, p. 31038-31045 8 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Pyruvaldehyde
Endothelial cells
Transcription
Endothelial Cells
7 Citations (Scopus)

Methylglyoxal Modification of mSin3A Links Glycolysis to Angiopoietin-2 Transcription (DOI:10.1016/j.cell.2005.11.024)

Yao, D., Taguchi, T., Matsumura, T., Pestell, R., Edelstein, D., Giardino, I., Suske, G., Ahmed, N., Thornalley, P. J., Sarthy, V. P., Hammes, H. P. & Brownlee, M., Feb 9 2007, In : Cell. 128, 3, 1 p.

Research output: Contribution to journalComment/debate

Angiopoietin-2
Pyruvaldehyde
Glycolysis
2006
69 Citations (Scopus)

Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription

Yao, D., Taguchi, T., Matsumura, T., Pestell, R., Edelstein, D., Giardino, I., Suske, G., Ahmed, N., Thornalley, P. J., Sarthy, V. P., Hammes, H. P. & Brownlee, M., Jan 27 2006, In : Cell. 124, 2, p. 275-286 12 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Pyruvaldehyde
Glycolysis
Transcription
Trioses
2005
44 Citations (Scopus)

Glutamate transport by retinal Müller cells in glutamate/aspartate transporter-knockout mice

Sarthy, V. P., Pignataro, L., Pannicke, T., Weick, M., Reichenbach, A., Harada, T., Tanaka, K. & Marc, R., Jan 15 2005, In : Glia. 49, 2, p. 184-196 13 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Knockout Mice
Glutamic Acid
Retina
Excitatory Amino Acid Transporter 5
10 Citations (Scopus)

Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors

Pignataro, L., Sitaramayya, A., Finnemann, S. C. & Sarthy, V. P., Jan 1 2005, In : Molecular and Cellular Neuroscience. 28, 3, p. 440-451 12 p.

Research output: Contribution to journalArticle

Excitatory Amino Acid Transporter 4
Retina
Rod Cell Outer Segment
Glutamic Acid
Sciuridae
2004
6 Citations (Scopus)

Contribution of a glial glutamate transporter to GABA synthesis in the retina

Sarthy, V. P., Marc, R. E., Pignataro, L. & Tanaka, K., Aug 26 2004, In : NeuroReport. 15, 12, p. 1895-1898 4 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Neuroglia
gamma-Aminobutyric Acid
Retina
Glutamic Acid
127 Citations (Scopus)
Retina
Nitric Oxide
Glucose
Aspirin
NG-Nitroarginine Methyl Ester
102 Citations (Scopus)
Glyceraldehyde-3-Phosphate Dehydrogenases
Selegiline
Apoptosis
Glucose
Hyperglycemia
1 Citation (Scopus)

Retinal glucose metabolism in mice lacking the L-glutamate/aspartate transporter

Sarthy, V. P., Dudley, V. J. & Tanaka, K., Jul 1 2004, In : Visual Neuroscience. 21, 4, p. 637-643 7 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Glutamic Acid
Lactic Acid
Glucose
Retina
2003
13 Citations (Scopus)

CRALBP transcriptional regulation in ciliary epithelial, retinal Müller and retinal pigment epithelial cells

Kennedy, B. N., Li, C., Ortego, J., Coca-Prados, M., Sarthy, V. P. & Crabb, J. W., Feb 1 2003, In : Experimental eye research. 76, 2, p. 257-260 4 p.

Research output: Contribution to journalArticle

Retinaldehyde
Retinal Pigments
Carrier Proteins
Retinal Pigment Epithelium
Epithelial Cells
45 Citations (Scopus)

GFAP promoter drives Müller cell-specific expression in transgenic mice

Kuzmanovic, M., Dudley, V. J. & Sarthy, V. P., Aug 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 8, p. 3606-3613 8 p.

Research output: Contribution to journalArticle

Glial Fibrillary Acidic Protein
Transgenic Mice
Retina
Ciliary Neurotrophic Factor
Genes
2002
35 Citations (Scopus)

Ciliary neurotrophic factor induces glial fibrillary acidic protein in retinal Müller cells through the JAK/STAT signal transduction pathway

Wang, Y., Smith, S. B., Ogilvie, J. M., McCool, D. J. & Sarthy, V. P., Oct 23 2002, In : Current eye research. 24, 4, p. 305-312 8 p.

Research output: Contribution to journalArticle

Ciliary Neurotrophic Factor
Glial Fibrillary Acidic Protein
Signal Transduction
Immunohistochemistry
Intravitreal Injections
7 Citations (Scopus)

Developmental expression of beta-catenin in mouse retina.

Liu, X., Sarthy, V. P., Craft, C. M., Honda, Y. & Ide, C., Jan 1 2002, In : Anatomical science international / Japanese Association of Anatomists. 77, 3, p. 182-188 7 p.

Research output: Contribution to journalArticle

beta Catenin
Retina
Ganglia
Catenins
Retinal Pigment Epithelium
2001
65 Citations (Scopus)

Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina

Shamsul Ola, M., Moore, P., El-Sherbeny, A., Roon, P., Agarwal, N., Sarthy, V. P., Casellas, P., Ganapathy, V. & Smith, S. B., Nov 1 2001, In : Molecular Brain Research. 95, 1-2, p. 86-95 10 p.

Research output: Contribution to journalArticle

Retina
Messenger RNA
Proteins
Ganglia
Retinal Pigments

The Retinal Muller cell- Structure and Function

Sarthy, V. & Ripps, H., 2001, New York: Kluwer Academic. 1 p.

Research output: Book/ReportBook

2000
11 Citations (Scopus)

Müller cells in retinal health and disease.

Sarthy, V. P., Jun 1 2000, In : Archivos de la Sociedad Espanola de Oftalmologia. 75, 6, p. 367-368 2 p.

Research output: Contribution to journalEditorial

Ciliary Neurotrophic Factor
Retinal Diseases
Retinal Vessels
Neuroglia
Extracellular Matrix
1999
12 Citations (Scopus)

Protection from oxidant injury by sodium-dependent GSH uptake in retinal Muller cells

Kannan, R., Bao, Y., Wang, Y., Sarthy, V. P. & Kaplowitz, N., Jan 1 1999, In : Experimental eye research. 68, 5, p. 609-616 8 p.

Research output: Contribution to journalArticle

Ependymoglial Cells
Oxidants
Sodium
Wounds and Injuries
tert-Butylhydroperoxide
29 Citations (Scopus)

Regulation of γ-glutamylcysteine synthetase subunit gene expression in retinal Muller cells by oxidative stress

Lu, S. C., Bao, Y., Huang, Z. Z., Sarthy, V. P. & Kannan, R., Jul 8 1999, In : Investigative Ophthalmology and Visual Science. 40, 8, p. 1776-1782 7 p.

Research output: Contribution to journalArticle

Glutamate-Cysteine Ligase
Ependymoglial Cells
Buthionine Sulfoximine
diethyl maleate
Oxidative Stress
1998
127 Citations (Scopus)

Establishment and characterization of a retinal Muller cell line

Sarthy, V. P., Brodjian, S. J., Dutt, K., Kennedy, B. N., French, R. P. & Crabb, J. W., Jan 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 1, p. 212-216 5 p.

Research output: Contribution to journalArticle

Ependymoglial Cells
Cell Line
Retinaldehyde
Carrier Proteins
Transfection
1997
3 Citations (Scopus)

Ciliary neurotrophic factor (CNTF) induces reactive gliosis and gfap expression in müller cells

Sarthy, V. P., Brodjian, S. J. & Smith, S. B., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4

Research output: Contribution to journalArticle

Ciliary Neurotrophic Factor
Gliosis
Glial Fibrillary Acidic Protein
Retina
Staining and Labeling

Cloning and localization of GABA and taurine transporters in mouse retina

Sarthy, V. P. & Sarkar, H. K., Jan 1 1997, In : Amino Acids. 13, 1, 1 p.

Research output: Contribution to journalArticle

GABA Plasma Membrane Transport Proteins
Cloning
taurine transporter
10 Citations (Scopus)

Glial fibrillary acidic protein (GFAP) is synthesized in the early stages of the photoreceptor cell degeneration of the mivit/mivit (vitiligo) mouse.

Smith, S. B., Brodjian, S., Desai, S. & Sarthy, V., Jan 1 1997, In : Experimental Eye Research. 64, 4, p. 645-650 6 p.

Research output: Contribution to journalArticle

Mutant Strains Mice
Retinal Diseases
Photoreceptor Cells
Vitiligo
Glial Fibrillary Acidic Protein
61 Citations (Scopus)

Molecular characterization and in situ localization of a mouse retinal taurine transporter

Vinnakota, S., Qian, X., Egal, H., Sarthy, V. & Sarkar, H. K., Dec 1 1997, In : Journal of neurochemistry. 69, 6, p. 2238-2250 13 p.

Research output: Contribution to journalArticle

Taurine
Brain
Equilibrium constants
Phorbol Esters
taurine transporter
1996
5 Citations (Scopus)

Cellular retinaldehyde-binding protein localization in cornea.

Sarthy, V., Jan 1 1996, In : Experimental eye research. 63, 6, p. 759-762 4 p.

Research output: Contribution to journalLetter

Retinaldehyde
Indirect Fluorescent Antibody Technique
Cornea
Carrier Proteins
1 Citation (Scopus)
Glial Fibrillary Acidic Protein
Cell Culture Techniques
Genes
3' Flanking Region
Lac Operon
2 Citations (Scopus)

Immunocytochemical localization of retinoid-binding protein in the dogfish retina

Sarthy, V. P. & Bickoff, C., Jan 1 1996, In : Current Eye Research. 15, 8, p. 905-907 3 p.

Research output: Contribution to journalArticle

Dogfish
Retinol-Binding Proteins
Retina
Vertebrates
Elasmobranchii
1995
28 Citations (Scopus)

Differential regulation of a glial fibrillary acidic protein-LacZ transgene in retinal astrocytes and Muller cells

Verderber, L., Johnson, W., Mucke, L. & Sarthy, V. P., Jan 1 1995, In : Investigative Ophthalmology and Visual Science. 36, 6, p. 1137-1143 7 p.

Research output: Contribution to journalArticle

Ependymoglial Cells
Glial Fibrillary Acidic Protein
Transgenes
Astrocytes
Retina
72 Citations (Scopus)

Indicator expression directed by regulatory sequences of the glial fibrillary acidic protein (GFAP) gene: In vivo comparison of distinct GFAP‐lacZ transgenes

Johnson, W. B., Ruppe, M. D., Rockenstein, E. M., Price, J., Sarthy, V. P., Verderber, L. C. & Mucke, L., Jan 1 1995, In : Glia. 13, 3, p. 174-184 11 p.

Research output: Contribution to journalArticle

Glial Fibrillary Acidic Protein
Galactosidases
Transgenes
Transgenic Mice
Genes
2 Citations (Scopus)

Localization of α-tubulin and carbonic anhydrase II mRNAs in isolated Müller cells

Sarthy, V. P., Jan 1 1995, In : Experimental eye research. 60, 1, p. 103-105 3 p.

Research output: Contribution to journalLetter

Genetic Transcription
Carbonic Anhydrase II
Carbonic Anhydrases
Glial Fibrillary Acidic Protein
Tubulin
19 Citations (Scopus)

Transient Induction of the Glial Intermediate Filament Protein Gene in Müller Cells in the Mouse Retina

Sarthy, V. P. & Egal, H., Jan 1 1995, In : DNA and Cell Biology. 14, 4, p. 313-320 8 p.

Research output: Contribution to journalArticle

Glial Fibrillary Acidic Protein
Retina
Genes
Light
Messenger RNA
1994
27 Citations (Scopus)

Cloning, expression, and localization of a mouse retinal γ-aminobutyric acid transporter

Ruiz, M., Egal, H., Sarthy, V., Qian, X. & Sarkar, H. K., Jan 1 1994, In : Investigative Ophthalmology and Visual Science. 35, 12, p. 4039-4048 10 p.

Research output: Contribution to journalArticle

Aminobutyrates
Organism Cloning
GABA Plasma Membrane Transport Proteins
gamma-Aminobutyric Acid
Complementary DNA
1993
32 Citations (Scopus)
In Situ Hybridization
Retina
Collagen
Messenger RNA
Lenses
94 Citations (Scopus)

Genetic and molecular identification of a Drosophila histidine decarboxylase gene required in photoreceptor transmitter synthesis

Burg, M. G., Sarthy, V. P., Koliantz, G. & Pak, W. L., Dec 1 1993, In : EMBO Journal. 12, 3, p. 911-919 9 p.

Research output: Contribution to journalArticle

Histidine Decarboxylase
Drosophila
Molecular Biology
Transmitters
Genes
1991
39 Citations (Scopus)

Developmental expression of the Glial fibrillary acidic protein (GFAP) gene in the mouse retina

Sarthy, P. V., Fu, M. & Huang, J., Dec 1 1991, In : Cellular and molecular neurobiology. 11, 6, p. 623-637 15 p.

Research output: Contribution to journalArticle

Glial Fibrillary Acidic Protein
Retina
Genes
Astrocytes
Ependymoglial Cells
68 Citations (Scopus)

Histamine: A Neurotransmitter Candidate for Drosophila Photoreceptors

Sarthy, V. P., Jan 1 1991, In : Journal of neurochemistry. 57, 5, p. 1757-1768 12 p.

Research output: Contribution to journalArticle

Histamine
Drosophila
Neurotransmitter Agents
Head
Invertebrate Photoreceptor Cells
1990
17 Citations (Scopus)

Intermediate filaments in the inner ear of normal and experimentally damaged guinea pigs

Oesterle, E. C., Sarthy, P. V. & Rubel, E. W., Aug 1 1990, In : Hearing Research. 47, 1-2, p. 1-16 16 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Inner Ear
Guinea Pigs
Vimentin
Glial Fibrillary Acidic Protein
53 Citations (Scopus)

Localization of laminin B1 mRNA in retinal ganglion cells by in situ hybridization

Sarthy, P. V. & Fu, M., Jan 1 1990, In : Journal of Cell Biology. 110, 6, p. 2099-2108 10 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Laminin
In Situ Hybridization
Retina
Messenger RNA
1989
4 Citations (Scopus)

A monoclonal antibody marker for the paraboloid region of cone photoreceptors in turtle retina

Gaur, V. P., Eldred, W., Possin, D. E. & Sarthy, P. V., Sep 1 1989, In : Cell and Tissue Research. 257, 3, p. 497-503 7 p.

Research output: Contribution to journalArticle

Retinal Cone Photoreceptor Cells
Turtles
Retina
Monoclonal Antibodies
Antibodies