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Article
2017

High glucose induces mitochondrial dysfunction in retinal müller cells: Implications for diabetic retinopathy

Tien, T., Zhang, J., Muto, T., Kim, D., Sarthy, V. P. & Roy, S., Jun 2017, In : Investigative Ophthalmology and Visual Science. 58, 7, p. 2915-2921 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
2015

Endothelin2 induces expression of genes associated with reactive gliosis in retinal müller cells

Sarthy, V. P., Sawkar, H. & Dudley, V. J., Jan 1 2015, In : Current Eye Research. 40, 11, p. 1181-1184 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014
32 Scopus citations
2013

Multimodal photoacoustic ophthalmoscopy in mouse

Song, W., Wei, Q., Feng, L., Sarthy, V., Jiao, S., Liu, X. & Zhang, H. F., Jun 1 2013, In : Journal of Biophotonics. 6, 6-7, p. 505-512 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Ciliary neurotrophic factor induces genes associated with inflammation and gliosis in the retina: A gene profiling study of flow-sorted, müller cells

Xue, W., Cojocaru, R. I., Dudley, V. J., Brooks, M., Swaroop, A. & Sarthy, V. P., May 31 2011, In : PloS one. 6, 5, e20326.

Research output: Contribution to journalArticle

35 Scopus citations

Gene expression changes in retinal Müller (Glial) cells exposed to elevated pressure

Xue, W., Du, P., Lin, S., Dudley, V. J., Hernandez, M. R. & Sarthy, V. P., Aug 1 2011, In : Current eye research. 36, 8, p. 754-767 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization

Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A., Eladl, M., Sarthy, V., Nussbaum, J., El-Marakby, A., Park, S. Y., Gurel, Z., Sheibani, N. & Maddipati, K. R., Feb 1 2011, In : Diabetes. 60, 2, p. 614-624 11 p.

Research output: Contribution to journalArticle

62 Scopus citations
2009

Differential regulation of high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation in müller cells by IL-1β and IL-6

Yego, E. C. K., Vincent, J. A., Sarthy, V., Busik, J. V. & Mohr, S., Apr 1 2009, In : Investigative Ophthalmology and Visual Science. 50, 4, p. 1920-1928 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network

Loewen, N., Chen, J., Dudley, V. J., Sarthy, V. P. & Mathura, J. R., May 1 2009, In : Experimental eye research. 88, 5, p. 928-937 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2007

Characterization of green fluorescent protein-expressing retinal cells in CD 44-transgenic mice

Sarthy, V., Hoshi, H., Mills, S. & Dudley, V. J., Feb 9 2007, In : Neuroscience. 144, 3, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

Yao, D., Taguchi, T., Matsumura, T., Pestell, R., Edelstein, D., Giardino, I., Suske, G., Rabbani, N., Thornalley, P. J., Sarthy, V. P., Hammes, H. P. & Brownlee, M., Oct 19 2007, In : Journal of Biological Chemistry. 282, 42, p. 31038-31045 8 p.

Research output: Contribution to journalArticle

174 Scopus citations
2006

Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription

Yao, D., Taguchi, T., Matsumura, T., Pestell, R., Edelstein, D., Giardino, I., Suske, G., Ahmed, N., Thornalley, P. J., Sarthy, V. P., Hammes, H. P. & Brownlee, M., Jan 27 2006, In : Cell. 124, 2, p. 275-286 12 p.

Research output: Contribution to journalArticle

69 Scopus citations
2005

Glutamate transport by retinal Müller cells in glutamate/aspartate transporter-knockout mice

Sarthy, V. P., Pignataro, L., Pannicke, T., Weick, M., Reichenbach, A., Harada, T., Tanaka, K. & Marc, R., Jan 15 2005, In : Glia. 49, 2, p. 184-196 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors

Pignataro, L., Sitaramayya, A., Finnemann, S. C. & Sarthy, V. P., Mar 2005, In : Molecular and Cellular Neuroscience. 28, 3, p. 440-451 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

Contribution of a glial glutamate transporter to GABA synthesis in the retina

Sarthy, V. P., Marc, R. E., Pignataro, L. & Tanaka, K., Aug 26 2004, In : NeuroReport. 15, 12, p. 1895-1898 4 p.

Research output: Contribution to journalArticle

6 Scopus citations
133 Scopus citations
103 Scopus citations

Retinal glucose metabolism in mice lacking the L-glutamate/aspartate transporter

Sarthy, V. P., Dudley, V. J. & Tanaka, K., Jul 1 2004, In : Visual Neuroscience. 21, 4, p. 637-643 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2003

CRALBP transcriptional regulation in ciliary epithelial, retinal Müller and retinal pigment epithelial cells

Kennedy, B. N., Li, C., Ortego, J., Coca-Prados, M., Sarthy, V. P. & Crabb, J. W., Feb 1 2003, In : Experimental eye research. 76, 2, p. 257-260 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

GFAP promoter drives Müller cell-specific expression in transgenic mice

Kuzmanovic, M., Dudley, V. J. & Sarthy, V. P., Aug 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 8, p. 3606-3613 8 p.

Research output: Contribution to journalArticle

46 Scopus citations
2002

Ciliary neurotrophic factor induces glial fibrillary acidic protein in retinal Müller cells through the JAK/STAT signal transduction pathway

Wang, Y., Smith, S. B., Ogilvie, J. M., McCool, D. J. & Sarthy, V., Oct 23 2002, In : Current eye research. 24, 4, p. 305-312 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Developmental expression of beta-catenin in mouse retina.

Liu, X., Sarthy, V. P., Craft, C. M., Honda, Y. & Ide, C., Sep 2002, In : Anatomical science international / Japanese Association of Anatomists. 77, 3, p. 182-188 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2001

Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina

Shamsul Ola, M., Moore, P., El-Sherbeny, A., Roon, P., Agarwal, N., Sarthy, V. P., Casellas, P., Ganapathy, V. & Smith, S. B., Nov 1 2001, In : Molecular Brain Research. 95, 1-2, p. 86-95 10 p.

Research output: Contribution to journalArticle

65 Scopus citations
1999

Protection from oxidant injury by sodium-dependent GSH uptake in retinal Muller cells

Kannan, R., Bao, Y., Wang, Y., Sarthy, V. P. & Kaplowitz, N., May 1999, In : Experimental eye research. 68, 5, p. 609-616 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Regulation of γ-glutamylcysteine synthetase subunit gene expression in retinal Muller cells by oxidative stress

Lu, S. C., Bao, Y., Huang, Z. Z., Sarthy, V. P. & Kannan, R., Jul 8 1999, In : Investigative Ophthalmology and Visual Science. 40, 8, p. 1776-1782 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
1998

Establishment and characterization of a retinal Muller cell line

Sarthy, V. P., Brodjian, S. J., Dutt, K., Kennedy, B. N., French, R. P. & Crabb, J. W., Jan 1 1998, In : Investigative Ophthalmology and Visual Science. 39, 1, p. 212-216 5 p.

Research output: Contribution to journalArticle

132 Scopus citations
1997

Ciliary neurotrophic factor (CNTF) induces reactive gliosis and gfap expression in müller cells

Sarthy, V. P., Brodjian, S. J. & Smith, S. B., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4

Research output: Contribution to journalArticle

3 Scopus citations

Cloning and localization of GABA and taurine transporters in mouse retina

Sarthy, V. P. & Sarkar, H. K., Jan 1 1997, In : Amino Acids. 13, 1, 1 p.

Research output: Contribution to journalArticle

Glial fibrillary acidic protein (GFAP) is synthesized in the early stages of the photoreceptor cell degeneration of the mivit/mivit (vitiligo) mouse.

Smith, S. B., Brodjian, S., Desai, S. & Sarthy, V., Apr 1997, In : Experimental eye research. 64, 4, p. 645-650 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Molecular characterization and in situ localization of a mouse retinal taurine transporter

Vinnakota, S., Qian, X., Egal, H., Sarthy, V. & Sarkar, H. K., Dec 1 1997, In : Journal of neurochemistry. 69, 6, p. 2238-2250 13 p.

Research output: Contribution to journalArticle

63 Scopus citations
1996
1 Scopus citations

Immunocytochemical localization of retinoid-binding protein in the dogfish retina

Sarthy, V. & Bickoff, C., Aug 1996, In : Current eye research. 15, 8, p. 905-907 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
1995

Differential regulation of a glial fibrillary acidic protein-LacZ transgene in retinal astrocytes and Muller cells

Verderber, L., Johnson, W., Mucke, L. & Sarthy, V. P., Jan 1 1995, In : Investigative Ophthalmology and Visual Science. 36, 6, p. 1137-1143 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Indicator expression directed by regulatory sequences of the glial fibrillary acidic protein (GFAP) gene: In vivo comparison of distinct GFAP‐lacZ transgenes

Johnson, W. B., Ruppe, M. D., Rockenstein, E. M., Price, J., Sarthy, V. P., Verderber, L. C. & Mucke, L., Jan 1 1995, In : Glia. 13, 3, p. 174-184 11 p.

Research output: Contribution to journalArticle

72 Scopus citations

Transient Induction of the Glial Intermediate Filament Protein Gene in Müller Cells in the Mouse Retina

Sarthy, V. & Egal, H., Apr 1995, In : DNA and Cell Biology. 14, 4, p. 313-320 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
1994

Cloning, expression, and localization of a mouse retinal γ-aminobutyric acid transporter

Ruiz, M., Egal, H., Sarthy, V., Qian, X. & Sarkar, H. K., Jan 1 1994, In : Investigative Ophthalmology and Visual Science. 35, 12, p. 4039-4048 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
1993
32 Scopus citations

Genetic and molecular identification of a Drosophila histidine decarboxylase gene required in photoreceptor transmitter synthesis

Burg, M. G., Sarthy, P. V., Koliantz, G. & Pak, W. L., 1993, In : EMBO Journal. 12, 3, p. 911-919 9 p.

Research output: Contribution to journalArticle

95 Scopus citations
1991

Developmental expression of the Glial fibrillary acidic protein (GFAP) gene in the mouse retina

Sarthy, P. V., Fu, M. & Huang, J., Dec 1 1991, In : Cellular and molecular neurobiology. 11, 6, p. 623-637 15 p.

Research output: Contribution to journalArticle

40 Scopus citations

Histamine: A Neurotransmitter Candidate for Drosophila Photoreceptors

Sarthy, P. V., Nov 1991, In : Journal of neurochemistry. 57, 5, p. 1757-1768 12 p.

Research output: Contribution to journalArticle

70 Scopus citations
1990

Intermediate filaments in the inner ear of normal and experimentally damaged guinea pigs

Oesterle, E. C., Sarthy, P. V. & Rubel, E. W., Aug 1 1990, In : Hearing research. 47, 1-2, p. 1-16 16 p.

Research output: Contribution to journalArticle

17 Scopus citations

Localization of laminin B1 mRNA in retinal ganglion cells by in situ hybridization

Sarthy, P. V. & Fu, M., Jan 1 1990, In : Journal of Cell Biology. 110, 6, p. 2099-2108 10 p.

Research output: Contribution to journalArticle

54 Scopus citations
1989

A monoclonal antibody marker for the paraboloid region of cone photoreceptors in turtle retina

Gaur, V. P., Eldred, W., Possin, D. E. & Sarthy, P. V., Sep 1 1989, In : Cell and Tissue Research. 257, 3, p. 497-503 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Localization of L‐glutamic acid decarboxylase mRNA in cat retinal horizontal cells by in situ hybridization

Sarthy, P. V. & Fu, M., Jan 1 1989, In : Journal of Comparative Neurology. 288, 4, p. 593-600 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Localization of L‐glutamic acid decarboxylase mRNA in monkey and human retina by in situ hybridization

Sarthy, P. V. & Fu, M., Jan 1 1989, In : Journal of Comparative Neurology. 288, 4, p. 691-697 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Subcellular localization of an intermediate filament protein and its mRNA in glial cells

Sarthy, P. V., Fu, M. & Huang, J., Jan 1 1989, In : Molecular and cellular biology. 9, 10, p. 4556-4559 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Transcriptional Activation of an Intermediate Filament Protein Gene in Mice with Retinal Dystrophy

Sarthy, P. V. & fu, M., Jul 1989, In : DNA. 8, 6, p. 437-446 10 p.

Research output: Contribution to journalArticle

50 Scopus citations
1988

A monoclonal antibody that binds to photoreceptors in the turtle retina

Gaur, V. P., Adamus, G., Arendt, A., Eldred, W., Possin, D. E., McDowell, J. H., Hargrave, P. A. & Sarthy, P. V., 1988, In : Vision Research. 28, 7, p. 765-776 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Distribution of Müller cells in the turtle retina: an immunocytochemical study

Gaur, V. P., Eldred, W. & Vijay Sarthy, P., Oct 1 1988, In : Journal of Neurocytology. 17, 5, p. 683-692 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Localization of glycine‐containing neurons in the Macaca monkey retina

Hendrickson, A. E., Koontz, M. A., Pourcho, R. G., Sarthy, P. V. & Goebel, D. J., Jan 1 1988, In : Journal of Comparative Neurology. 273, 4, p. 473-487 15 p.

Research output: Contribution to journalArticle

86 Scopus citations