• 5219 Citations

Research output per year

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Personal profile

Research Interests

Using electron microscopy, digital image reconstruction, biophysics and a diversity of biochemical approaches, his lab study the structure and function of membrane proteins and membrane-associated scaffolds. Currently their efforts focus on the mechanisms by which cells acquire and distribute copper ions, and how cells change the shape of their membranes.

Education/Academic qualification

Biochemistry, PhD, University of Cambridge

… → 1995

Biochemistry, Diploma, University of Tübingen

… → 1991

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Research Output

Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells

Jayakanthan, S., Braiterman, L. T., Hasan, N. M., Unger, V. M. & Lutsenko, S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 18760-18774 15 p.

Research output: Contribution to journalArticle

  • 18 Scopus citations

    Protein-mediated membrane remodeling

    Daumke, O. & Unger, V. M., Oct 1 2016, In : Journal of Structural Biology. 196, 1, p. 1-2 2 p.

    Research output: Contribution to journalEditorial

    Structure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy

    Chen, P. H., Unger, V. & He, X., Dec 4 2015, In : Journal of Molecular Biology. 427, 24, p. 3921-3934 14 p.

    Research output: Contribution to journalArticle

  • 19 Scopus citations

    Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers

    Opatowsky, Y., Lax, I., Tomé, F., Bleichert, F., Unger, V. M. & Schlessinger, J., Feb 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 5, p. 1772-1777 6 p.

    Research output: Contribution to journalArticle

  • 18 Scopus citations

    Atox1 contains positive residues that mediate membrane association and aid subsequent copper loading

    Flores, A. G. & Unger, V. M., Sep 16 2013, In : Journal of Membrane Biology. 246, 12, p. 903-913 11 p.

    Research output: Contribution to journalArticle

  • 18 Scopus citations