Grants per year
Personal profile
Research Interests
Using electron microscopy, digital image reconstruction, biophysics and a diversity of biochemical approaches, his lab study the structure and function of membrane proteins and membrane-associated scaffolds. Currently their efforts focus on the mechanisms by which cells acquire and distribute copper ions, and how cells change the shape of their membranes.
Education/Academic qualification
Biochemistry, PhD, University of Cambridge
… → 1995
Biochemistry, Diploma, University of Tübingen
… → 1991
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Grants
- 8 Finished
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Structure and Function of Mammalian Copper Transporters
National Institute of General Medical Sciences
9/15/16 → 7/31/19
Project: Research project
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Structure and Function of F-BAR Protein Membrane Remodeling Interactions
American Heart Association Midwest Affiliate
7/1/13 → 4/4/14
Project: Research project
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MRI: Development of a Cryogenic Sample Preparation Instrument (NU CRYOCLUSTER)
Joester, D., Dravid, V. P., Gaillard, J., Shah, R. N., Woloschak, G. E., Jacobsen, C., Jewett, M. C., Marko, J. F., Mrksich, M., O'Halloran, T. V., Shull, K. R., Stupp, S., Unger, V. M. & Wang, Y.
9/1/12 → 8/31/16
Project: Research project
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IN-009: Direct Electron Detector for the Biological CryoEm
Walsh, J. & Unger, V. M.
Searle Funds at The Chicago Community Trust
1/1/11 → 12/31/17
Project: Research project
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Structural Biology of Membrane Scaffolds
National Institute of General Medical Sciences
9/1/10 → 8/31/15
Project: Research project
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Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells
Jayakanthan, S., Braiterman, L. T., Hasan, N. M., Unger, V. M. & Lutsenko, S., Nov 17 2017, In: Journal of Biological Chemistry. 292, 46, p. 18760-18774 15 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Protein-mediated membrane remodeling
Daumke, O. & Unger, V. M., Oct 1 2016, In: Journal of Structural Biology. 196, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial › peer-review
1 Scopus citations -
Structure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy
Chen, P. H., Unger, V. & He, X., Dec 4 2015, In: Journal of Molecular Biology. 427, 24, p. 3921-3934 14 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers
Opatowsky, Y., Lax, I., Tomé, F., Bleichert, F., Unger, V. M. & Schlessinger, J., Feb 4 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 5, p. 1772-1777 6 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Atox1 contains positive residues that mediate membrane association and aid subsequent copper loading
Flores, A. G. & Unger, V. M., Dec 2013, In: Journal of Membrane Biology. 246, 12, p. 903-913 11 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations