• 5307 Citations
1969 …2020

Research output per year

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Research Output

2014

Structure determination, refinement, and validation

Minasov, G. & Anderson, W. F., Jan 1 2014, In : Methods in Molecular Biology. 1140, p. 239-249 11 p.

Research output: Contribution to journalArticle

Structure of the LdcB LD-carboxypeptidase reveals the molecular basis of peptidoglycan recognition

Hoyland, C. N., Aldridge, C., Cleverley, R. M., Duchêne, M. C., Minasov, G., Onopriyenko, O., Sidiq, K., Stogios, P. J., Anderson, W. F., Daniel, R. A., Savchenko, A., Vollmer, W. & Lewis, R. J., Jul 8 2014, In : Structure. 22, 7, p. 949-960 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Targeting DXP synthase in human pathogens: Enzyme inhibition and antimicrobial activity of butylacetylphosphonate

Smith, J. M., Warrington, N. V., Vierling, R. J., Kuhn, M. L., Anderson, W. F., Koppisch, A. T. & Freel Meyers, C. L., Jan 1 2014, In : Journal of Antibiotics. 67, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Type III effector NleH2 from Escherichia coli O157:H7 str. Sakai features an atypical protein kinase domain

Halavaty, A. S., Anderson, S. M., Wawrzak, Z., Kudritska, M., Skarina, T., Anderson, W. F. & Savchenko, A., Apr 22 2014, In : Biochemistry. 53, 15, p. 2433-2435 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Virtual high-throughput ligand screening

Andrew Binkowski, T., Jiang, W., Roux, B., Anderson, W. F. & Joachimiak, A., Jan 1 2014, In : Methods in Molecular Biology. 1140, p. 251-261 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Acetylation of the response regulator RcsB controls transcription from a small RNA promoter

Hu, L. I., Chi, B. K., Kuhn, M. L., Filippova, E. V., Walker-Peddakotla, A. J., Bäsell, K., Becher, D., Anderson, W. F., Antelmann, H. & Wolfe, A. J., Sep 5 2013, In : Journal of bacteriology. 195, 18, p. 4174-4186 13 p.

Research output: Contribution to journalArticle

61 Scopus citations

A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4

Krishna, S. N., Luan, C. H., Mishra, R. K., Xu, L., Scheidt, K. A., Anderson, W. F. & Bergan, R. C., Dec 5 2013, In : PloS one. 8, 12, e81504.

Research output: Contribution to journalArticle

24 Scopus citations

Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity

Kuhn, M. L., Majorek, K. A., Minor, W. & Anderson, W. F., Feb 1 2013, In : Protein Science. 22, 2, p. 222-230 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Characterization of fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae

Seo, H. S., Minasov, G., Seepersaud, R., Doran, K. S., Dubrovska, I., Shuvalova, L., Anderson, W. F., Iverson, T. M. & Sullam, P. M., Dec 13 2013, In : Journal of Biological Chemistry. 288, 50, p. 35982-35996 15 p.

Research output: Contribution to journalArticle

46 Scopus citations

Crystal structure of a type II dehydroquinate dehydratase-like protein from Bifidobacterium longum

Light, S. H., Krishna, S. N., Bergan, R. C., Lavie, A. & Anderson, W. F., Mar 1 2013, In : Journal of Structural and Functional Genomics. 14, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction

Watterson, D. M., Grum-Tokars, V. L., Roy, S. M., Schavocky, J. P., de Bradaric, B., Bachstetter, A. D., Xing, B., Dimayuga, E., Saeed, F., Zhang, H., Staniszewski, A., Pelletier, J. C., Minasov, G., Anderson, W. F., Arancio, O. & van Eldik, L. J., Jun 26 2013, In : PloS one. 8, 6, e66226.

Research output: Contribution to journalArticle

47 Scopus citations

Large scale structural rearrangement of a serine hydrolase from francisella tularensis facilitates catalysis

Filippova, E. V., Weston, L. A., Kuhn, M. L., Geissler, B., Gehring, A. M., Armoush, N., Adkins, C. T., Minasov, G., Dubrovska, I., Shuvalova, L., Winsor, J. R., Lavis, L. D., Satchell, K. J. F., Becker, D. P., Anderson, W. F. & Johnson, R. J., Apr 12 2013, In : Journal of Biological Chemistry. 288, 15, p. 10522-10535 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

LigSearch: A knowledge-based web server to identify likely ligands for a protein target

De Beer, T. A. P., Laskowski, R. A., Duban, M. E., Edith Chan, A. W., Anderson, W. F. & Thornton, J. M., Dec 2013, In : Acta Crystallographica Section D: Biological Crystallography. 69, 12, p. 2395-2402 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Reassessing the Type i dehydroquinate dehydratase catalytic triad: Kinetic and structural studies of Glu86 mutants

Light, S. H., Anderson, W. F. & Lavie, A., Apr 1 2013, In : Protein Science. 22, 4, p. 418-424 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
25 Scopus citations

Structure and activity of the NAD(P)+-dependent succinate semialdehyde dehydrogenase YneI from Salmonella typhimurium

Zheng, H., Beliavsky, A., Tchigvintsev, A., Brunzelle, J. S., Brown, G., Flick, R., Evdokimova, E., Wawrzak, Z., Mahadevan, R., Anderson, W. F., Savchenko, A. & Yakunin, A. F., Jun 1 2013, In : Proteins: Structure, Function and Bioinformatics. 81, 6, p. 1031-1041 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

The diversity of allosteric controls at the gateway to aromatic amino acid biosynthesis

Light, S. H. & Anderson, W. F., Apr 2013, In : Protein Science. 22, 4, p. 395-404 10 p.

Research output: Contribution to journalReview article

26 Scopus citations
2012

Bacillus anthracis inosine 5′-monophosphate dehydrogenase in action: The first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes

Makowska-Grzyska, M., Kim, Y., Wu, R., Wilton, R., Gollapalli, D. R., Wang, X. K., Zhang, R., Jedrzejczak, R., MacK, J. C., Maltseva, N., Mulligan, R., Binkowski, T. A., Gornicki, P., Kuhn, M. L., Anderson, W. F., Hedstrom, L. & Joachimiak, A., Aug 7 2012, In : Biochemistry. 51, 31, p. 6148-6163 16 p.

Research output: Contribution to journalArticle

26 Scopus citations

Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni

Zheng, H., Filippova, E. V., Tkaczuk, K. L., Dworzynski, P., Chruszcz, M., Porebski, P. J., Wawrzak, Z., Onopriyenko, O., Kudritska, M., Grimshaw, S., Savchenko, A., Anderson, W. F. & Minor, W., Mar 1 2012, In : Journal of Structural and Functional Genomics. 13, 1, p. 15-26 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain

Light, S. H., Halavaty, A. S., Minasov, G., Shuvalova, L. & Anderson, W. F., Jun 2012, In : Protein Science. 21, 6, p. 887-895 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Structural and functional characterization of microcin C resistance peptidase MccF from bacillus anthracis

Nocek, B., Tikhonov, A., Babnigg, G., Gu, M., Zhou, M., Makarova, K. S., Vondenhoff, G., Aerschot, A. V., Kwon, K., Anderson, W. F., Severinov, K. & Joachimiak, A., Jul 20 2012, In : Journal of Molecular Biology. 420, 4-5, p. 366-383 18 p.

Research output: Contribution to journalArticle

18 Scopus citations

Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria

Halavaty, A. S., Kim, Y., Minasov, G., Shuvalova, L., Dubrovska, I., Winsor, J., Zhou, M., Onopriyenko, O., Skarina, T., Papazisi, L., Kwon, K., Peterson, S. N., Joachimiak, A., Savchenko, A. & Anderson, W. F., Oct 1 2012, In : Acta Crystallographica Section D: Biological Crystallography. 68, 10, p. 1359-1370 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU

Halavaty, A. S., Borek, D., Tyson, G. H., Veesenmeyer, J. L., Shuvalova, L., Minasov, G., Otwinowski, Z., Hauser, A. R. & Anderson, W. F., Nov 14 2012, In : PloS one. 7, 11, e49388.

Research output: Contribution to journalArticle

25 Scopus citations

The crystal structures of the a-subunit of the α2β 2 tetrameric Glycyl-tRNA synthetase

Tan, K., Zhou, M., Zhang, R., Anderson, W. F. & Joachimiak, A., Dec 1 2012, In : Journal of Structural and Functional Genomics. 13, 4, p. 233-239 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

A conserved surface loop in type i dehydroquinate dehydratases positions an active site arginine and functions in substrate binding

Light, S. H., Minasov, G., Shuvalova, L. A., Peterson, S. N., Caffrey, M., Anderson, W. F. & Lavie, A., Mar 29 2011, In : Biochemistry. 50, 12, p. 2357-2363 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
27 Scopus citations
9 Scopus citations

Crystal structure of the novel PaiB transcriptional regulator from Geobacillus stearothermophilus

Filippova, E. V., Brunzelle, J. S., Cuff, M. E., Li, H., Joachimiak, A. & Anderson, W. F., Aug 1 2011, In : Proteins: Structure, Function and Bioinformatics. 79, 8, p. 2578-2582 5 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates

Light, S. H., Minasov, G., Shuvalova, L. A., Duban, M. E., Caffrey, M., Anderson, W. F. & Lavie, A., Feb 4 2011, In : Journal of Biological Chemistry. 286, 5, p. 3531-3539 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2010

Role of the membrane localization domain of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicity

Veesenmeyer, J. L., Howell, H., Halavaty, A. S., Ahrens, S., Anderson, W. F. & Hauser, A. R., Aug 1 2010, In : Infection and immunity. 78, 8, p. 3346-3357 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases

Tchigvintsev, A., Xu, X., Singer, A., Chang, C., Brown, G., Proudfoot, M., Cui, H., Flick, R., Anderson, W. F., Joachimiak, A., Galperin, M. Y., Savchenko, A. & Yakunin, A. F., Sep 2010, In : Journal of Molecular Biology. 402, 3, p. 524-538 15 p.

Research output: Contribution to journalArticle

76 Scopus citations

To automate or not to automate: This is the question

Cymborowski, M., Klimecka, M., Chruszcz, M., Zimmerman, M. D., Shumilin, I. A., Borek, D., Lazarski, K., Joachimiak, A., Otwinowski, Z., Anderson, W. & Minor, W., Sep 2010, In : Journal of Structural and Functional Genomics. 11, 3, p. 211-221 11 p.

Research output: Contribution to journalReview article

20 Scopus citations
2009

Crystal structures of Ykul and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains

Minasov, G., Padavattan, S., Shuvalova, L., Brunzelle, J. S., Miller, D. J., Baslé, A., Massa, C., Collart, F. R., Schirmer, T. & Anderson, W. F., May 8 2009, In : Journal of Biological Chemistry. 284, 19, p. 13174-13184 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

MEK4 function, genistein treatment, and invasion of human prostate cancer cells

Xu, L., Ding, Y., Catalona, W. J., Yang, X. J., Anderson, W. F., Jovanovic, B., Wellman, K., Killmer, J., Huang, X., Scheidt, K. A., Montgomery, R. B. & Bergan, R. C., Aug 2009, In : Journal of the National Cancer Institute. 101, 16, p. 1141-1155 15 p.

Research output: Contribution to journalArticle

68 Scopus citations

Structural and molecular mechanism for autoprocessing of MARTX toxin of vibrio cholerae at multiple sites

Prochazkova, K., Shuvalova, L. A., Minasov, G., Voburka, Z., Anderson, W. F. & Satchell, K. J. F., Sep 25 2009, In : Journal of Biological Chemistry. 284, 39, p. 26557-26568 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Structural genomics and drug discovery for infectious diseases

Anderson, W. F., Oct 5 2009, In : Infectious Disorders - Drug Targets. 9, 5, p. 507-517 11 p.

Research output: Contribution to journalArticle

32 Scopus citations
2007

Crystal structure of an apo form of Shigella flexneri ArsH protein with an NADPH-dependent FMN reductase activity

Vorontsov, I. I., Minasov, G., Brunzelle, J. S., Shuvalova, L., Kiryukhina, O., Collart, F. R. & Anderson, W. F., Nov 1 2007, In : Protein Science. 16, 11, p. 2483-2490 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Structural and biochemical characterization of a novel Mn 2+-dependent phosphodiesterase encoded by the yfcE gene

Miller, D. J., Shuvalova, L., Evdokimova, E., Savchenko, A., Yakunin, A. F. & Anderson, W. F., Jul 2007, In : Protein Science. 16, 7, p. 1338-1348 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

The 2.2 Å resolution crystal structure of Bacillus cereus Nif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory domain

Godsey, M. H., Minasov, G., Shuvalova, L., Brunzelle, J. S., Vorontsov, I. I., Collart, F. R. & Anderson, W. F., Jul 1 2007, In : Protein Science. 16, 7, p. 1285-1293 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2006

Crystal structure of YfiR, an unusual TetR/CamR-type putative transcriptional regulator from Bacillus subtilis

Rajan, S. S., Yang, X., Shuvalova, L., Collart, F. & Anderson, W. F., Oct 1 2006, In : Proteins: Structure, Function and Genetics. 65, 1, p. 255-257 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2005

Crystal structure of a predicted precorrin-8x methylmutase from Thermoplasma acidophilum

Cuff, M. E., Miller, D. J., Korolev, S., Xu, X., Anderson, W. F., Edwards, A., Joachimiak, A. & Savchenko, A., Feb 15 2005, In : Proteins: Structure, Function and Genetics. 58, 3, p. 751-754 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: Structural insight into specificity for phospho-β-D- glucosides

Varrot, A., Yip, V. L. Y., Li, Y., Rajan, S. S., Yang, X., Anderson, W. F., Thompson, J., Withers, S. G. & Davies, G. J., Feb 18 2005, In : Journal of Molecular Biology. 346, 2, p. 423-435 13 p.

Research output: Contribution to journalArticle

43 Scopus citations
2004

An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 β-glycosidase from Thermotoga maritima

Yip, V. L. Y., Varrot, A., Davies, G. J., Rajan, S. S., Yang, X., Thompson, J., Anderson, W. F. & Withers, S. G., Jul 14 2004, In : Journal of the American Chemical Society. 126, 27, p. 8354-8355 2 p.

Research output: Contribution to journalArticle

94 Scopus citations

Crystal structure of Bacillus subtilis YdaF protein: A putative ribosomal N-acetyltransferase

Brunzelle, J. S., Wu, R., Korolev, S. V., Collart, F. R., Joachimiak, A. & Anderson, W. F., Dec 1 2004, In : Proteins: Structure, Function and Genetics. 57, 4, p. 850-853 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+-dependent phospho-α-glucosidase from Bacillus subtilis

Rajan, S. S., Yang, X., Collart, F., Yip, V. L. Y., Withers, S. G., Varrot, A., Thompson, J., Davies, G. J. & Anderson, W. F., Sep 1 2004, In : Structure. 12, 9, p. 1619-1629 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology

Rajan, S. S., Yang, X., Shuvalova, L. A., Collart, F. & Anderson, W. F., Dec 14 2004, In : Biochemistry. 43, 49, p. 15472-15479 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
2003

Automated crystallographic system for high-throughput protein structure determination

Brunzelle, J. S., Shafaee, P., Yang, X., Weigand, S., Ren, Z. & Anderson, W. F., Jul 1 2003, In : Acta Crystallographica Section D: Biological Crystallography. 59, 7, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments

VanLoock, M. S., Yu, X., Yang, S., Galkin, V. E., Huang, H., Rajan, S. S., Anderson, W. F., Stohl, E. A., Seifert, H. S. & Egelman, E. H., Oct 17 2003, In : Journal of Molecular Biology. 333, 2, p. 345-354 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain

Miller, D. J., Ouellette, N., Evdokimova, E., Savchenko, A., Edwards, A. & Anderson, W. F., Jul 1 2003, In : Protein Science. 12, 7, p. 1432-1442 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Structure of the Bacillus subtilis YYCN Protein: A Putative N-Acetyltransferase

Taneja, B., Maar, S., Shuvalova, L., Collart, F., Anderson, W. & Mondragón, A., Dec 1 2003, In : Proteins: Structure, Function and Genetics. 53, 4, p. 950-952 3 p.

Research output: Contribution to journalArticle