• 3901 Citations

Research output per year

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Personal profile

Research Interests

Dr. Zhang's major research interests include the genetics and epigenetics of complex traits, such as risks for common diseases, drug response, and gene expression. Dr. Zhang is also developing novel epigenetics-based biomarkers for various human cancers and chronic diseases using liquid biopsy.

Education/Academic qualification

PhD, University of Vermont

… → 2004

Research interests

  • Bioinformatics
  • Cancer Genetics
  • Epigenetics
  • Genomic Medicine/Personalized Medicine
  • Health Disparities
  • Microbiome
  • Systems Biology
  • Translational Research

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  • Research Output

    Enhanced CXCR4 expression associates with increased gene body 5-hydroxymethylcytosine modification but not decreased promoter methylation in colorectal cancer

    Stuckel, A. J., Zhang, W., Zhang, X., Zeng, S., Dougherty, U., Mustafi, R., Zhang, Q., Perreand, E., Khare, T., Joshi, T., West-Szymanski, D. C., Bissonnette, M. & Khare, S., Mar 2020, In : Cancers. 12, 3, 539.

    Research output: Contribution to journalArticle

    Open Access
  • 5-Hydroxymethylcytosines in circulating cell-free DNA reveal vascular complications of type 2 diabetes

    Yang, Y., Zeng, C., Lu, X., Song, Y., Nie, J., Ran, R., Zhang, Z., He, C., Zhang, W. & Liu, S. M., Jan 1 2019, In : Clinical chemistry. 65, 11, p. 1414-1425 12 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers (Cell Research, (2017), 27, 10, (1243-1257), 10.1038/cr.2017.121)

    Li, W., Zhang, X., Lu, X., You, L., Song, Y., Luo, Z., Zhang, J., Nie, J., Zheng, W., Xu, D., Wang, Y., Dong, Y., Yu, S., Hong, J., Shi, J., Hao, H., Luo, F., Hua, L., Wang, P., Qian, X. & 17 others, Yuan, F., Wei, L., Cui, M., Zhang, T., Liao, Q., Dai, M., Liu, Z., Chen, G., Meckel, K., Adhikari, S., Jia, G., Bissonnette, M. B., Zhang, X., Zhao, Y., Zhang, W., He, C. & Liu, J., Jul 1 2019, In : Cell Research. 29, 7, 1 p.

    Research output: Contribution to journalComment/debate

    Open Access
  • Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma

    Cai, J., Chen, L., Zhang, Z., Zhang, X., Lu, X., Liu, W., Shi, G., Ge, Y., Gao, P., Yang, Y., Ke, A., Xiao, L., Dong, R., Zhu, Y., Yang, X., Wang, J., Zhu, T., Yang, D., Huang, X., Sui, C. & 15 others, Qiu, S., Shen, F., Sun, H., Zhou, W., Zhou, J., Nie, J., Zeng, C., Stroup, E. K., Zhang, X., Chiu, B. C. H., Lau, W. Y., He, C., Wang, H., Zhang, W. & Fan, J., Dec 1 2019, In : Gut. 68, 12, p. 2195-2205 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • 20 Scopus citations

    Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma

    Chiu, B. C. H., Zhang, Z., You, Q., Zeng, C., Stepniak, E., Bracci, P. M., Yu, K., Venkataraman, G., Smith, S. M., He, C. & Zhang, W., Oct 8 2019, In : Blood Advances. 3, 19, p. 2790-2799 10 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations