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Wei Zhang

  • 3656 Citations
20072024
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Personal profile

Research Interests

Dr. Zhang's major research interests include the genetics and epigenetics of complex traits, such as risks for common diseases, drug response, and gene expression. Dr. Zhang is also developing novel epigenetics-based biomarkers for various human cancers and chronic diseases using liquid biopsy.

Education/Academic qualification

PhD, University of Vermont

… → 2004

Research interests

  • Bioinformatics
  • Cancer Genetics
  • Epigenetics
  • Genomic Medicine/Personalized Medicine
  • Health Disparities
  • Microbiome
  • Systems Biology
  • Translational Research

Fingerprint Dive into the research topics where Wei Zhang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Gene Expression Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Genes Medicine & Life Sciences
HapMap Project Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Genome Medicine & Life Sciences
Pharmacogenetics Medicine & Life Sciences
Epigenomics Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2014 2024

CXCR4 as a target for colon cancer chemoprevention

Zhang, W.

University of Chicago, National Cancer Institute

7/1/19 → 6/30/24

Project: Research project

Chemoprevention
Colonic Neoplasms
Colorectal Neoplasms
Biological Products
Carcinogenesis

Epigenomic markers of circulating cell-free DNA and treatment outcome in multiple myeloma

Zhang, W.

University of Chicago, National Cancer Institute

7/1/18 → 6/30/23

Project: Research project

5-Methylcytosine
Multiple Myeloma
Epigenomics
Recurrence
DNA

Vascular-Targeting Genomic and Genetic Strategies for Acute Chest Syndrome

Zhang, W.

Indiana University, National Heart, Lung, and Blood Institute

5/4/18 → 4/30/22

Project: Research project

Acute Chest Syndrome
Blood Vessels
Lung Injury
Biomarkers
Bronchopulmonary Sequestration

Effects of Flame Retardants on brain function and attentional deficits in school-age children – brain imaging, neurobehavioral, and gut microbiome studies in a longitudinal birth cohort

Zhang, W.

Columbia University, National Institute of Environmental Health Sciences

1/1/18 → 3/31/23

Project: Research project

Flame Retardants
Computational Biology
Neuroimaging
Biostatistics
Parturition

Using epigenomic subtyping to understand the racial differences in lymphoma

Zhang, W.

University of Chicago, National Institute on Minority Health and Health Disparities

9/25/17 → 5/31/20

Project: Research project

Computational Biology
Epigenomics
Lymphoma
Biostatistics
Manuscripts

Research Output 2007 2019

Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers (Cell Research, (2017), 27, 10, (1243-1257), 10.1038/cr.2017.121)

Li, W., Zhang, X., Lu, X., You, L., Song, Y., Luo, Z., Zhang, J., Nie, J., Zheng, W., Xu, D., Wang, Y., Dong, Y., Yu, S., Hong, J., Shi, J., Hao, H., Luo, F., Hua, L., Wang, P., Qian, X. & 17 others, Yuan, F., Wei, L., Cui, M., Zhang, T., Liao, Q., Dai, M., Liu, Z., Chen, G., Meckel, K., Adhikari, S., Jia, G., Bissonnette, M. B., Zhang, X., Zhao, Y., Zhang, W., He, C. & Liu, J., Jul 1 2019, In : Cell Research. 29, 7, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access
Tumor Biomarkers
Gene Expression
DNA
Research
Neoplasms
1 Citation (Scopus)

Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma

Chiu, B. C. H., Zhang, Z., You, Q., Zeng, C., Stepniak, E., Bracci, P. M., Yu, K., Venkataraman, G., Smith, S. M., He, C. & Zhang, W., Oct 8 2019, In : Blood Advances. 3, 19, p. 2790-2799 10 p.

Research output: Contribution to journal › Article

Open Access
Lymphoma, Large B-Cell, Diffuse
DNA
Disease-Free Survival
Proportional Hazards Models
Survival

Significant association of eed promoter hypomethylation with colorectal cancer

Ying, X., Pan, R., Zhong, J., Wu, B., Jiang, Y., Ying, J., Zhou, C., Dai, J., Zhao, S., Shen, Y., Zhang, W. & Duan, S., Aug 1 2019, In : Oncology Letters. 18, 2, p. 1564-1570 7 p.

Research output: Contribution to journal › Article

Open Access
Ectoderm
Embryonic Development
Colorectal Neoplasms
Methylation
Neoplasms
6 Citations (Scopus)

Towards precision medicine: Advances in 5-hydroxymethylcytosine cancer biomarker discovery in liquid biopsy

Zeng, C., Stroup, E. K., Zhang, Z., Chiu, B. C. H. & Zhang, W., Mar 29 2019, In : Cancer Communications. 39, 1, 12.

Research output: Contribution to journal › Review article

Precision Medicine
Tumor Biomarkers
Epigenomics
Biopsy
DNA
6 Citations (Scopus)

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma

Pangeni, R. P., Zhang, Z., Alvarez, A. A., Wan, X., Sastry, N., Lu, S., Shi, T., Huang, T., Lei, C. X., James, C. D., Kessler, J., Brennan, C. W., Nakano, I., Lu, X., Hu, B., Zhang, W. & Cheng, S-Y., Apr 3 2018, In : Epigenetics. 13, 4, p. 432-448 17 p.

Research output: Contribution to journal › Article

Glioblastoma
Epigenomics
Glioma
Stem Cells
Genome