Grants per year
Personal profile
Research Interests
Dr. Zhang's major research interests include the genetics and epigenetics of complex traits, such as risks for common diseases, drug response, and gene expression. Dr. Zhang is also developing novel epigenetics-based biomarkers for various human cancers and chronic diseases using liquid biopsy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Microbiology, University of Vermont
… → 2004
Research interests keywords
- Bioinformatics
- Cancer Genetics
- Epigenetics
- Genomic Medicine/Personalized Medicine
- Health Disparities
- Microbiome
- Systems Biology
- Translational Research
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Collaborations and top research areas from the last five years
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Pleiotropic Role of PAI-1 in Cardiovascular Aging
Vaughan, D. E., Abdala-Valencia, H., Burridge, P., Wilsbacher, L. D. & Zhang, W.
National Heart, Lung, and Blood Institute
8/1/23 → 5/31/28
Project: Research project
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Targeting RNA Splicing in Glioma
National Institute of Neurological Disorders and Stroke
7/1/22 → 4/30/27
Project: Research project
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CXCR4 as a target for colon cancer chemoprevention
The University of Chicago, National Cancer Institute
7/1/19 → 6/30/24
Project: Research project
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Methodological development of epigenetic biomarkers in esophageal cancer
7/1/20 → 6/30/22
Project: Research project
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Advances in biomarker discovery using circulating cell-free DNA for early detection of hepatocellular carcinoma
Liu, M., Zhang, Z., Zhang, W. & Liu, S. M., May 1 2023, In: WIREs mechanisms of disease. 15, 3, e1598.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Associations of MTHFR Polymorphisms and Cytosine Modifications with Early-Gestational Diabetes Mellitus in Chinese Pregnant Women
Liu, H. Y., Qin, S., Zhang, Z., Qi, J., Zhang, W., Liu, S. M. & Zhang, Y., 2023, (Accepted/In press) In: Reproductive Sciences.Research output: Contribution to journal › Article › peer-review
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Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis
Zeng, C., Song, X., Zhang, Z., Cai, Q., Cai, J., Horbinski, C., Hu, B., Cheng, S. Y. & Zhang, W., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 133.Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease
Beadell, A. V., Zhang, Z., Capuano, A. W., Bennett, D. A., He, C., Zhang, W. & Arvanitakis, Z., 2023, In: Journal of Alzheimer's Disease. 93, 3, p. 1135-1151 17 p.Research output: Contribution to journal › Article › peer-review
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Geospatial analysis of population-based incidence of multiple myeloma in the United States
Cheung, J. T. H., Zhang, W. & Chiu, B. C. H., Apr 2023, In: Cancer Epidemiology. 83, 102343.Research output: Contribution to journal › Article › peer-review
Datasets
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Associations of two-pore domain potassium channels and triple negative breast cancer subtype in The Cancer Genome Atlas: systematic evaluation of gene expression and methylation
Dookeran, K. A. (Creator), Zhang, W. (Creator), Stayner, L. (Creator) & Argos, M. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3878248.v1, https://figshare.com/collections/Associations_of_two-pore_domain_potassium_channels_and_triple_negative_breast_cancer_subtype_in_The_Cancer_Genome_Atlas_systematic_evaluation_of_gene_expression_and_methylation/3878248/1
Dataset
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MOESM4 of Associations of two-pore domain potassium channels and triple negative breast cancer subtype in The Cancer Genome Atlas: systematic evaluation of gene expression and methylation
Dookeran, K. A. (Creator), Zhang, W. (Creator), Stayner, L. (Creator) & Argos, M. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3878248_d4, https://springernature.figshare.com/articles/dataset/MOESM4_of_Associations_of_two-pore_domain_potassium_channels_and_triple_negative_breast_cancer_subtype_in_The_Cancer_Genome_Atlas_systematic_evaluation_of_gene_expression_and_methylation/5401180
Dataset
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Additional file 4: Table S4. of Characterization of genome-wide H3K27ac profiles reveals a distinct PM2.5-associated histone modification signature
Liu, C. (Creator), Xu, J. (Contributor), Chen, Y. (Contributor), Guo, X. (Contributor), Zheng, Y. (Contributor), Wang, Q. (Contributor), Chen, Y. (Contributor), Ni, Y. (Creator), Zhu, Y. (Contributor), Joyce, B. (Creator), Baccarelli, A. (Creator), Deng, F. (Contributor), Zhang, W. (Creator), Hou, L. (Contributor), Yahong, C. (Contributor), Qianfei, W. (Contributor), Yiyong, C. (Contributor), Yidan, Z. (Contributor) & Baccarelli, A. (Creator), figshare, 2015
DOI: 10.6084/m9.figshare.c.3610925_d2, https://springernature.figshare.com/articles/dataset/Additional_file_4_Table_S4_of_Characterization_of_genome-wide_H3K27ac_profiles_reveals_a_distinct_PM2_5-associated_histone_modification_signature/4361933
Dataset
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MOESM3 of Associations of two-pore domain potassium channels and triple negative breast cancer subtype in The Cancer Genome Atlas: systematic evaluation of gene expression and methylation
Dookeran, K. A. (Creator), Zhang, W. (Creator), Stayner, L. (Creator) & Argos, M. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3878248_d3, https://springernature.figshare.com/articles/dataset/MOESM3_of_Associations_of_two-pore_domain_potassium_channels_and_triple_negative_breast_cancer_subtype_in_The_Cancer_Genome_Atlas_systematic_evaluation_of_gene_expression_and_methylation/5401153
Dataset
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Characterization of CpG sites that escape methylation on the inactive human X-chromosome
Moen, E. L. (Creator), Litwin, E. (Creator), Arnovitz, S. (Creator), Zhang, X. (Creator), Zhang, W. (Creator), Dolan, M. E. (Contributor), Godley, L. A. (Creator) & Moen, E. L. (Creator), Taylor & Francis, 2015
DOI: 10.6084/m9.figshare.1485315.v4, https://figshare.com/articles/Characterization_of_CpG_sites_that_escape_methylation_on_the_inactive_human_X_chromosome/1485315/4
Dataset