• 3347 Citations
20072023
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Personal profile

Research Interests

Dr. Zhang's major research interests include the genetics and epigenetics of complex traits, such as risks for common diseases, drug response, and gene expression. Dr. Zhang is also developing novel epigenetics-based biomarkers for various human cancers and chronic diseases using liquid biopsy.

Education/Academic qualification

PhD, University of Vermont

… → 2004

Keywords

  • Bioinformatics
  • Cancer Genetics
  • Epigenetics
  • Genomic Medicine/Personalized Medicine
  • Health Disparities
  • Microbiome
  • Systems Biology
  • Translational Research

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Grants 2014 2023

5-Methylcytosine
Multiple Myeloma
Epigenomics
Recurrence
DNA
Acute Chest Syndrome
Blood Vessels
Lung Injury
Biomarkers
Bronchopulmonary Sequestration
Glioblastoma
Epigenomics
Biomarkers
Brain Neoplasms
Therapeutics
Computational Biology
Epigenomics
Colonic Neoplasms
Biomarkers
Biostatistics

Research Output 2007 2019

Towards precision medicine: Advances in 5-hydroxymethylcytosine cancer biomarker discovery in liquid biopsy

Zeng, C., Stroup, E. K., Zhang, Z., Chiu, B. C. H. & Zhang, W., Mar 29 2019, In : Cancer Communications. 39, 1, 12.

Research output: Contribution to journalReview article

Precision Medicine
Tumor Biomarkers
Epigenomics
Biopsy
DNA
1 Citation (Scopus)

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma

Pangeni, R. P., Zhang, Z., Alvarez, A. A., Wan, X., Sastry, N., Lu, S., Shi, T., Huang, T., Lei, C. X., James, C. D., Kessler, J., Brennan, C. W., Nakano, I., Lu, X., Hu, B., Zhang, W. & Cheng, S-Y., Apr 3 2018, In : Epigenetics. 13, 4, p. 432-448 17 p.

Research output: Contribution to journalArticle

Glioblastoma
Epigenomics
Glioma
Stem Cells
Genome
24 Citations (Scopus)

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

Li, W., Zhang, X., Lu, X., You, L., Song, Y., Luo, Z., Zhang, J., Nie, J., Zheng, W., Xu, D., Wang, Y., Dong, Y., Yu, S., Hong, J., Shi, J., Hao, H., Luo, F., Hua, L., Wang, P., Qian, X. & 17 othersYuan, F., Wei, L., Cui, M., Zhang, T., Liao, Q., Dai, M., Liu, Z., Chen, G., Meckel, K., Adhikari, S., Jia, G., Bissonnette, M. B., Zhang, X., Zhao, Y., Zhang, W., He, C. & Liu, J., Oct 1 2017, In : Cell Research. 27, 10, p. 1243-1257 15 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
DNA
Biomarkers
Epigenomics
Stomach Neoplasms
Triple Negative Breast Neoplasms
Methylation
Atlases
Potassium Channels
Gene expression
5 Citations (Scopus)

Blood pressure and expression of microRNAs in whole blood

Zhang, Z., Joyce, B. T., Kresovich, J. K., Zheng, Y., Zhong, J., Patel, R., Zhang, W., Liu, L., Dou, C., McCracken, J. P., DõÂaz, A., Motta, V., Sanchez-Guerra, M., Bian, S., Bertazzi, P. A., Schwartz, J., Baccarelli, A. A., Wang, S. & Hou, L., Mar 1 2017, In : PloS one. 12, 3, e0173550.

Research output: Contribution to journalArticle

Blood pressure
MicroRNAs
microRNA
blood pressure
Blood