Grants per year
Personal profile
Training Experience
| 1999 | Postdoctoral Fellowship, Washington University School of Medicine |
Education/Academic qualification
MD, PhD, University of Pittsburgh
… → 1995
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 22 Similar Profiles
Corpus Striatum
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Neuronal Plasticity
Medicine & Life Sciences
Parkinson Disease
Medicine & Life Sciences
Dopamine
Medicine & Life Sciences
Synapses
Medicine & Life Sciences
Outer Auditory Hair Cells
Medicine & Life Sciences
Cholinergic Agents
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2003 2021
Molecular and Cellular Mechanisms of Parkinson’s Disease
Guzman-Lucero, J. N., Kondapalli, J., Shen, W., Surmeier Jr, D. J. & Wokosin, D. L.
11/1/18 → 10/31/21
Project: Research project
Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Molecular and Cellular Mechanisms of Parkinson's Disease
Guzman-Lucero, J. N., Kondapalli, J., Schumacker, P. T., Shen, W., Surmeier Jr, D. J. & Wokosin, D. L.
9/1/15 → 10/31/19
Project: Research project
Levodopa
Parkinson Disease
Dyskinesias
Dopaminergic Neurons
Muscarinic M4 Receptors
Evaluation of Acute Effects of Amantadine on Corticostriatal Synaptic Plasticity in a Mouse Model of L-DOPA-Induced Dyskinesia.
2/1/17 → 11/1/18
Project: Research project
Amantadine
Neuronal Plasticity
Dyskinesias
Neurons
Brain
Targeting M4 muscarinic receptors for the treatment of L-Dopa-induced dyskinesia
Michael J. Fox Foundation for Parkinson's Research
3/1/15 → 9/17/16
Project: Research project
Muscarinic M4 Receptors
Dyskinesias
Levodopa
Synapses
Long-Term Synaptic Depression
Molecular and Cellular Mechanisms of Parkinson's Disease
Guzman-Lucero, J. N., Kondapalli, J., Shen, W., Surmeier Jr, D. J., Wokosin, D. L. & Xie, Z.
9/1/12 → 8/31/15
Project: Research project
Research Output 1994 2018
Striatal cholinergic interneurons and Parkinson's disease
Tanimura, A., Pancani, T., Lim, S. A. O., Tubert, C., Melendez, A. E., Shen, W. & Surmeier Jr, D. J., May 1 2018, In : European Journal of Neuroscience. 47, 10, p. 1148-1158 11 p.Research output: Contribution to journal › Review article
Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease
Optogenetics
Striatal synapses, circuits, and Parkinson's disease
Zhai, S., Tanimura, A., Graves, S. M., Shen, W. & Surmeier Jr, D. J., Feb 1 2018, In : Current opinion in neurobiology. 48, p. 9-16 8 p.Research output: Contribution to journal › Review article
Corpus Striatum
Synapses
Parkinson Disease
Aptitude
Basal Ganglia
Dopaminergic Modulation of Glutamatergic Signaling in Striatal Spiny Projection Neurons
Shen, W., Plokin, J. L., Zhai, S. & Surmeier Jr, D. J., Jan 1 2017, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 179-196 18 p. (Handbook of Behavioral Neuroscience; vol. 24).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Corpus Striatum
Dopamine
Neurons
Learning
Dopamine D1 Receptors
Erratum: M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia (Neuron (2015) 88 (762–773))
Shen, W., Plotkin, JL. L., Francardo, V., Ko, WKD. K. D., Xie, Z., Li, Q., Fieblinger, T., Wess, J., Neubig, RR. R., Lindsley, CW. W., Conn, P. J., Greengard, P., Bezard, E., Cenci, M. A. & Surmeier, D. J., Jun 1 2016, In : Neuron. 90, 5, 1 p.Research output: Contribution to journal › Comment/debate
Muscarinic M4 Receptors
Corpus Striatum
Neuronal Plasticity
Manuscripts
Dyskinesias
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia
Shen, W., Plotkin, J. L., Francardo, V., Ko, W. K. D., Xie, Z., Li, Q., Fieblinger, T., Wess, J., Neubig, R. R., Lindsley, C. W., Conn, P. J., Greengard, P., Bezard, E., Cenci, M. A. & Surmeier Jr, D. J., Nov 18 2015, In : Neuron. 88, 4, p. 762-773 12 p.Research output: Contribution to journal › Article
Muscarinic M4 Receptors
Corpus Striatum
Long-Term Potentiation
Dyskinesias
Levodopa