Weixing Shen

  • 4079 Citations
1994 …2021

Research output per year

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Research Output

  • 4079 Citations
  • 21 Article
  • 7 Review article
  • 4 Chapter
  • 1 Comment/debate
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Article
2015

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

Shen, W., Plotkin, J. L., Francardo, V., Ko, W. K. D., Xie, Z., Li, Q., Fieblinger, T., Wess, J., Neubig, R. R., Lindsley, C. W., Conn, P. J., Greengard, P., Bezard, E., Cenci, M. A. & Surmeier, D. J., Nov 18 2015, In : Neuron. 88, 4, p. 762-773 12 p.

Research output: Contribution to journalArticle

94 Scopus citations
2013

Regulation of dendritic calcium release in striatal spiny projection neurons

Plotkin, J. L., Shen, W., Rafalovich, I., Sebel, L. E., Day, M., Savio Chan, C. & James Surmeier, D., Nov 15 2013, In : Journal of neurophysiology. 110, 10, p. 2325-2336 12 p.

Research output: Contribution to journalArticle

26 Scopus citations
2012

Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice

Chan, S., Peterson, J. D., Gertler, T. S., Glajch, K. E., Quintana, R. E., Cui, Q., Sebel, L. E., Plotkin, J. L., Shen, W., Heiman, M., Heintz, N., Greengard, P. & Surmeier Jr, D. J., Jul 4 2012, In : Journal of Neuroscience. 32, 27, p. 9124-9132 9 p.

Research output: Contribution to journalArticle

41 Scopus citations
2010

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

Bateup, H. S., Santini, E., Shen, W., Birnbaum, S., Valjent, E., Surmeier, D. J., Fisone, G., Nestler, E. J. & Greengard, P., Aug 17 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 33, p. 14845-14850 6 p.

Research output: Contribution to journalArticle

225 Scopus citations
2008

Dichotomous dopaminergic control of striatal synaptic plasticity

Shen, W., Flajolet, M., Greengard, P. & Surmeier Jr, D. J., Aug 8 2008, In : Science. 321, 5890, p. 848-851 4 p.

Research output: Contribution to journalArticle

709 Scopus citations

FGF acts as a co-transmitter through adenosine A 2A receptor to regulate synaptic plasticity

Flajolet, M., Wang, Z., Futter, M., Shen, W., Nuangchamnong, N., Bendor, J., Wallach, I., Nairn, A. C., Surmeier Jr, D. J. & Greengard, P., Dec 1 2008, In : Nature Neuroscience. 11, 12, p. 1402-1409 8 p.

Research output: Contribution to journalArticle

122 Scopus citations
2007

Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons

Shen, W., Tian, X., Day, M., Ulrich, S., Tkatch, T., Nathanson, N. M. & Surmeier, D. J., Nov 1 2007, In : Nature Neuroscience. 10, 11, p. 1458-1466 9 p.

Research output: Contribution to journalArticle

163 Scopus citations
2005

Cholinergic suppression of KCNQ channel currents enhances excitability of striatal medium spiny neurons

Shen, W., Hamilton, S. E., Nathanson, N. M. & Surmeier, D. J., Aug 10 2005, In : Journal of Neuroscience. 25, 32, p. 7449-7458 10 p.

Research output: Contribution to journalArticle

151 Scopus citations
2004

Kv1.2-Containing K+ Channels Regulate Subthreshold Excitability of Striatal Medium Spiny Neurons

Shen, W., Hernandez-Lopez, S., Tkatch, T., Held, J. E. & Surmeier, D. J., Mar 1 2004, In : Journal of neurophysiology. 91, 3, p. 1337-1349 13 p.

Research output: Contribution to journalArticle

77 Scopus citations
2001

Effects of membrane potential and tension on prestin, the outer hair cell lateral membrane motor protein

Santos-Sacchi, J., Shen, W., Zheng, J. & Dallos, P., Mar 15 2001, In : Journal of Physiology. 531, 3, p. 661-666 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Effects on γ-aminobutyric acid (GABA)A receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission

Mennerick, S., Zeng, C. M., Benz, A., Shen, W., Izumi, Y., Evers, A. S., Covey, D. F. & Zorumski, C. F., Oct 8 2001, In : Molecular Pharmacology. 60, 4, p. 732-741 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Prestin topology: Localization of protein epitopes in relation to the plasma membrane

Zheng, J., Long, K. B., Shen, W., Madison, L. D. & Dallos, P., Jul 3 2001, In : Neuroreport. 12, 9, p. 1929-1935 7 p.

Research output: Contribution to journalArticle

84 Scopus citations

Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats

Vallée, M., Shen, W., Heinrichs, S. C., Zorumski, C. F., Covey, D. F., Koob, G. F. & Purdy, R. H., Dec 1 2001, In : European Journal of Neuroscience. 14, 12, p. 2003-2010 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2000

Pregnenolone sulfate modulates inhibitory synaptic transmission by enhancing GABA(A) receptor desensitization

Shen, W., Mennerick, S., Covey, D. F. & Zorumski, C. F., May 15 2000, In : Journal of Neuroscience. 20, 10, p. 3571-3579 9 p.

Research output: Contribution to journalArticle

83 Scopus citations
1999

Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors

Shen, W., Mennerick, S., Zorumski, E. C., Covey, D. F. & Zorumski, C. F., Feb 1 1999, In : Neuropharmacology. 38, 2, p. 267-271 5 p.

Research output: Contribution to journalArticle

51 Scopus citations

Substrate turnover by transporters curtails synaptic glutamate transients

Mennerick, S., Shen, W., Xu, W., Benz, A., Tanaka, K., Shimamoto, K., Isenberg, K. E., Krause, J. E. & Zorumski, C. F., Nov 1 1999, In : Journal of Neuroscience. 19, 21, p. 9242-9251 10 p.

Research output: Contribution to journalArticle

85 Scopus citations
1998

Effect of nitrous oxide on excitatory and inhibitory synaptic transmission in hippocampal cultures

Mennerick, S., Jevtovic-Todorovic, V., Todorovic, S. M., Shen, W., Olney, J. W. & Zorumski, C. F., Dec 1 1998, In : Journal of Neuroscience. 18, 23, p. 9716-9726 11 p.

Research output: Contribution to journalArticle

146 Scopus citations

Mecamylamine selectively blocks nicotinic receptors on vasomotor sympathetic C neurons

Shen, W. X. & Horn, J. P., Mar 30 1998, In : Brain research. 788, 1-2, p. 118-124 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
1996

Presynaptic muscarinic inhibition in bullfrog sympathethic ganglia

Shen, W. X. & Horn, J. P., Mar 1 1996, In : Journal of Physiology. 491, 2, p. 413-421 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
1995

A presynaptic mechanism accounts for the differential block of nicotinic synapses on sympathetic B and C neurons by d-tubocurarine

Shen, W. X. & Horn, J. P., Jan 1 1995, In : Journal of Neuroscience. 15, 7 I, p. 5025-5035 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
1994

The sensitivity of nicotinic synapses in bullfrog sympathetic ganglia to α‐bungarotoxin and neuronal‐bungarotoxin

Shen, WX. X., Jobling, P. & Horn, J. P., Nov 1994, In : British journal of pharmacology. 113, 3, p. 898-902 5 p.

Research output: Contribution to journalArticle

2 Scopus citations