Grants per year
Personal profile
Research Interests
The focus of my research efforts centered on the effect of bone graft substitutes in pre-clinical animal models. Our publications looked at the effects of viral-mediated gene therapy, bone morphogenetic protein (BMP), adipose-derived stem cells, and demineralized bone matrix in a variety of rodent bone healing models in the extremity and spine. Furthermore, our research group studied the effects of novel imaging to track in vivo bone formation and metabolic activity. My current focus of research is aligned with my research partner and wife, Dr. Erin Hsu, who is a Research Assistant Professor at Northwestern University. Our work investigates the role of the Aryl Hydrocarbon Receptor (Ahr) with a focus on gene and protein expression changes and downstream effects after activation by xenobiotics such as dioxin and its role on osteogenic differentiation and bone healing. This has led to publications suggesting that the mechanism in which smoking increases the risk of fracture nonunion is mediated by Ahr ligands and not nicotine. Another arm of our research aims to develop and evaluate novel technologies involving both nanomaterials and 3D-printing methodologies to ultimately produce a universally safe and effective bone graft substitute for use in humans. I serve as PI or Co-Investigator on all of these studies.
Certifications and Licenses
Orthopaedic Surgery |
Training Experience
2007 | Residency, Univ. of CA-Los Angeles Med. Ctr. |
2008 | Fellowship, Univ. of Wisconsin Hospital |
Education/Academic qualification
Medicine, MD, Vanderbilt University
… → 2001
Research interests keywords
- Biomaterials
- Spinal Biomechanics
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Grants
- 24 Finished
-
Rat Paraspinal Neuroinflammation Model-to Study Host Response to rhPDGF-BB Combined with a Beta-tricalcium Phosphate (b-TCP)/Bovine Collagen Matrix
Hsu, E. L., Hsu, W. K. & Yun, C.
Wright Medical Technology, Inc.
5/9/18 → 5/9/21
Project: Research project
-
Resveratrol as a Therapeutic to Reverse the Adverse Effects of Cigarette Smoke on Bone
Cervical Spine Research Society
1/1/17 → 10/1/18
Project: Research project
-
Development of 3D-printed hyperelastic bone composites for bone regeneration and spine fusion
Hsu, E. L., Hsu, W. K., Shah, R. N., Stock, S. R. & Yun, C.
Orthopaedic Research and Education Foundation
7/1/16 → 6/30/17
Project: Research project
-
Congenital Cervical Stenosis: a Review of the Current Literature
Goodwin, A. M. & Hsu, W. K., Sep 2023, In: Current Reviews in Musculoskeletal Medicine. 16, 9, p. 438-445 8 p.Research output: Contribution to journal › Review article › peer-review
-
Patient and Surgeon Perceptions Regarding Microdiscectomy Surgery: A Cross-Sectional Analysis of Social Media Posts
Roumeliotis, A. G., Swiatek, P. R., Goedderz, C., Mathur, P., Zhang, Y., Gerlach, E. B., Divi, S. N., Hsu, W. K. & Patel, A. A., Jun 1 2023, In: International Journal of Spine Surgery. 17, 3, p. 434-441 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Social Media Posts Pertaining to Anterior Cervical Discectomy and Fusion (ACDF) Surgery: A Cross-sectional Analysis of Patient and Surgeon Perceptions
Swiatek, P. R., Roumeliotis, A. G., Weiner, J. A., Ramesh, A., Johnson, D. J., Gerlach, E. B., Divi, S. N., Hsu, W. K. & Patel, A. A., Jun 1 2023, In: Clinical spine surgery. 36, 5, p. E167-E173Research output: Contribution to journal › Article › peer-review
-
The Role of Cervical Disc Arthroplasty in Elite Athletes
Brecount, H., Goodwin, A., Hiltzik, D. M. & Hsu, W. K., Sep 2023, In: Current Reviews in Musculoskeletal Medicine. 16, 9, p. 432-437 6 p.Research output: Contribution to journal › Review article › peer-review
-
Using Machine Learning and Deep Learning Algorithms to Predict Postoperative Outcomes Following Anterior Cervical Discectomy and Fusion
Khazanchi, R., Bajaj, A., Shah, R. M., Chen, A. R., Reyes, S. G., Kurapaty, S. S., Hsu, W. K., Patel, A. A. & Divi, S. N., Apr 1 2023, In: Clinical spine surgery. 36, 3, p. 143-149 7 p.Research output: Contribution to journal › Article › peer-review
Datasets
-
The Effectiveness of Bioskills Training for Simulated Lumbar Pedicle Screw Placement
Boody, B. S. (Creator), Hashmi, S. Z. (Contributor), Rosenthal, B. D. (Creator), Maslak, J. P. (Creator), McCarthy, M. H. (Creator), Patel, A. A. (Contributor), Savage, J. W. (Creator), Hsu, W. K. (Contributor) & Alpesh A., P. (Contributor), figshare, 2019
DOI: 10.25384/sage.c.4222898.v2, https://sage.figshare.com/collections/The_Effectiveness_of_Bioskills_Training_for_Simulated_Lumbar_Pedicle_Screw_Placement/4222898/2
Dataset