No photo of Wellington K Hsu

View Scopus Profile

Wellington K Hsu

  • 3406 Citations
20032020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

The focus of my research efforts centered on the effect of bone graft substitutes in pre-clinical animal models. Our publications looked at the effects of viral-mediated gene therapy, bone morphogenetic protein (BMP), adipose-derived stem cells, and demineralized bone matrix in a variety of rodent bone healing models in the extremity and spine. Furthermore, our research group studied the effects of novel imaging to track in vivo bone formation and metabolic activity. My current focus of research is aligned with my research partner and wife, Dr. Erin Hsu, who is a Research Assistant Professor at Northwestern University. Our work investigates the role of the Aryl Hydrocarbon Receptor (Ahr) with a focus on gene and protein expression changes and downstream effects after activation by xenobiotics such as dioxin and its role on osteogenic differentiation and bone healing. This has led to publications suggesting that the mechanism in which smoking increases the risk of fracture nonunion is mediated by Ahr ligands and not nicotine. Another arm of our research aims to develop and evaluate novel technologies involving both nanomaterials and 3D-printing methodologies to ultimately produce a universally safe and effective bone graft substitute for use in humans. I serve as PI or Co-Investigator on all of these studies.

Certifications and Licenses

Orthopaedic Surgery

Training Experience

2007Residency, Univ. of CA-Los Angeles Med. Ctr.
2008Fellowship, Univ. of Wisconsin Hospital

Education/Academic qualification

MD, Vanderbilt University

… → 2001

Research interests

  • Biomaterials
  • Spinal Biomechanics

Fingerprint Dive into the research topics where Wellington K Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants

Prot# CP-010: Prospective Evaluation on Lumbar Discectomy with Additional Implantation of an Annular Closure Device in Patients with Large Postsurgical Annular Defects for Prevention of Lumbar Disc Reherniation

Hsu, W. K.

Intrinsic Therapeutics, Inc.

3/18/20 → 3/18/23

Project: Research project

Prot# CT-17-001:Safety and Effectiveness of Bio2 Vitrium® Cervical Cage in Anterior Cervical Discectomy and Fusion. A Randomized, Controlled, Non-inferiority, Pivotal Study.

Hsu, W. K.

Bio2 Technologies, Inc.

8/20/19 → 8/20/22

Project: Research project

A BMP-2-binding nanofiber—Demineralized bone matrix composite scaffold as a bone graft substitute for spinal fusion

Hsu, E. L., Hsu, W. K., Stock, S. R. & Stupp, S.

Musculoskeletal Transplant Foundation, Inc.

8/1/19 → 7/31/22

Project: Research project

Supramolecular nanofibers for recombinant growth factor-free spine fusion

Hsu, E. L., Hsu, W. K., Stock, S. R. & Stupp, S.

National Institute of Arthritis and Musculoskeletal and Skin Diseases

7/12/18 → 4/30/23

Project: Research project

    • Prot#1006:An Assessment of P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion with Instrumentation

    Hsu, W. K.

    Emergent Clinical Consulting, LLC, Cerapedics, Inc.

    6/26/18 → 6/25/21

    Project: Research project

    Research Output

    3D-Printed Ceramic-Demineralized Bone Matrix Hyperelastic Bone Composite Scaffolds for Spinal Fusion

    Driscoll, J. A., Lubbe, R., Jakus, A. E., Chang, K., Haleem, M., Yun, C., Singh, G., Schneider, A. D., Katchko, K. M., Soriano, C., Newton, M., Maerz, T., Li, X., Baker, K., Hsu, W. K., Shah, R. N., Stock, S. R. & Hsu, E. L., Feb 2020, In : Tissue Engineering - Part A. 26, 3-4, p. 157-166 10 p.

    Research output: Contribution to journal › Article

    • Association between Opioid Use and Patient-Reported Outcomes in a Randomized Trial Evaluating Basivertebral Nerve Ablation for the Relief of Chronic Low Back Pain

    Markman, J. D., Rhyne, A. L., Sasso, R. C., Patel, A. A., Hsu, W. K., Fischgrund, J. S., Edidin, A. A. & Vajkoczy, P., Mar 1 2020, In : Clinical Neurosurgery. 86, 3, p. 343-347 5 p.

    Research output: Contribution to journal › Article

    Open Access

    • Burden of Sciatica on US Medicare Recipients

    Maslak, J. P., Jenkins, T. J., Weiner, J. A., Kannan, A. S., Patoli, D. M., McCarthy, M. H., Hsu, W. K. & Patel, A. A., May 15 2020, In : The Journal of the American Academy of Orthopaedic Surgeons. 28, 10, p. e433-e439

    Research output: Contribution to journal › Article

    Open Access

    • Can the American College of Surgeons Risk Calculator Predict 30-day Complications After Spine Surgery?

    McCarthy, M. H., Singh, P., Nayak, R., Maslak, J. P., Jenkins, T. J., Patel, A. A. & Hsu, W. K., May 1 2020, In : Spine. 45, 9, p. 621-628 8 p.

    Research output: Contribution to journal › Article

    • No S.C.A.R.E. Protocol: A Streamlined Safety Protocol

    Jenkins, T. J., Snowden, R. D., Smucker, J., Hsu, W. K., Riew, K. D. & Sasso, R. C., Jan 1 2020, In : The Journal of the American Academy of Orthopaedic Surgeons. 28, 1, p. 21-28 8 p.

    Research output: Contribution to journal › Article

    Open Access