Wellington K Hsu

  • 2989 Citations
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Personal profile

Research Interests

The focus of my research efforts centered on the effect of bone graft substitutes in pre-clinical animal models. Our publications looked at the effects of viral-mediated gene therapy, bone morphogenetic protein (BMP), adipose-derived stem cells, and demineralized bone matrix in a variety of rodent bone healing models in the extremity and spine. Furthermore, our research group studied the effects of novel imaging to track in vivo bone formation and metabolic activity. My current focus of research is aligned with my research partner and wife, Dr. Erin Hsu, who is a Research Assistant Professor at Northwestern University. Our work investigates the role of the Aryl Hydrocarbon Receptor (Ahr) with a focus on gene and protein expression changes and downstream effects after activation by xenobiotics such as dioxin and its role on osteogenic differentiation and bone healing. This has led to publications suggesting that the mechanism in which smoking increases the risk of fracture nonunion is mediated by Ahr ligands and not nicotine. Another arm of our research aims to develop and evaluate novel technologies involving both nanomaterials and 3D-printing methodologies to ultimately produce a universally safe and effective bone graft substitute for use in humans. I serve as PI or Co-Investigator on all of these studies.

Certifications and Licenses

Orthopaedic Surgery

Training Experience

2007Residency, Univ. of CA-Los Angeles Med. Ctr.
2008Fellowship, Univ. of Wisconsin Hospital

Education/Academic qualification

MD, Vanderbilt U

… → 2001

Research interests

  • Biomaterials
  • Spinal Biomechanics

Fingerprint Dive into the research topics where Wellington K Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
Spine Medicine & Life Sciences
Athletes Medicine & Life Sciences
Diskectomy Medicine & Life Sciences
Spinal Fusion Medicine & Life Sciences
Football Medicine & Life Sciences
Arthrodesis Medicine & Life Sciences
Bone and Bones Medicine & Life Sciences
Sports Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2010 2023

Research Output 2003 2019

2 Citations (Scopus)

Anatomic Considerations in the Lateral Transpsoas Interbody Fusion: The Impact of Age, Sex, BMI, and Scoliosis

Mai, H. T., Schneider, A. D., Alvarez, A. P., Hashmi, S. Z., Smith, J. T., Freshman, R. D., Mitchell, S. M., Qin, C. D. & Hsu, W. K., Jun 1 2019, In : Clinical Spine Surgery. 32, 5, p. 215-221 7 p.

Research output: Contribution to journalArticle

Blood Vessels
Lumbosacral Plexus
Anatomic Variation

Controversies in the management of cervical spine conditions in elite athletes

Pahapill, R. R. & Hsu, W. K., Jan 1 2019, In : Orthopedics. 42, 4, p. E370-E375

Research output: Contribution to journalReview article

Wounds and Injuries
4 Citations (Scopus)

Cost-effectiveness of a Bone-anchored Annular Closure Device Versus Conventional Lumbar Discectomy in Treating Lumbar Disc Herniations

Ament, J., Thaci, B., Yang, Z., Kulubya, E., Hsu, W. K., Bouma, G. & Kim, K. D., Jan 1 2019, In : Spine. 44, 1, p. 5-16 12 p.

Research output: Contribution to journalArticle

Cost-Benefit Analysis
Bone and Bones
Equipment and Supplies
Costs and Cost Analysis
1 Citation (Scopus)

Intervertebral disc herniation in elite athletes

Yamaguchi, J. T. & Hsu, W. K., Apr 4 2019, In : International Orthopaedics. 43, 4, p. 833-840 8 p.

Research output: Contribution to journalReview article

Intervertebral Disc
Neck Pain
3 Citations (Scopus)

Prognosis Following Hip Arthroscopy Varies in Professional Athletes Based on Sport

Christian, R. A., Lubbe, R. J., Chun, D. S., Selley, R. S., Terry, M. A. & Hsu, W. K., Mar 1 2019, In : Arthroscopy - Journal of Arthroscopic and Related Surgery. 35, 3, p. 837-842.e1

Research output: Contribution to journalArticle