Wenan Qiang

  • 1123 Citations
1994 …2022

Research output per year

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Research Output

  • 1123 Citations
  • 64 Article
  • 2 Comment/debate
  • 2 Review article
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Article
2019

Anti-inflammatory activities of Sigesbeckia glabrescens Makino: Combined in vitro and in silico investigations

Zhong, Z., Zhang, Q., Tao, H., Sang, W., Cui, L., Qiang, W., Cheang, W. S., Hu, Y., Yu, H. & Wang, Y., Sep 23 2019, In : Chinese Medicine (United Kingdom). 14, 1, 35.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
2 Scopus citations

Human organoids share structural and genetic features with primary pancreatic adenocarcinoma tumors

Romero-Calvo, I., Weber, C. R., Ray, M., Brown, M., Kirby, K., Nandi, R. K., Long, T. M., Sparrow, S. M., Ugolkov, A., Qiang, W., Zhang, Y., Brunetti, T., Kindler, H., Segal, J. P., Rzhetsky, A., Mazar, A. P., Buschmann, M. M., Weichselbaum, R., Roggin, K. & White, K. P., Jan 1 2019, In : Molecular Cancer Research. 17, 1, p. 70-83 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b

Lin, K., Qiang, W., Zhu, M., Ding, Y., Shi, Q., Chen, X., Zsiros, E., Wang, K., Yang, X., Kurita, T. & Xu, E. Y., Feb 26 2019, In : Cell reports. 26, 9, p. 2434-2450.e6

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2018

Cellular kinetics of MED12-mutant uterine leiomyoma growth and regression in vivo

Serna, V. A., Wu, X., Qiang, W., Thomas, J., Blumenfeld, M. L. & Kurita, T., Jul 2018, In : Endocrine-related cancer. 25, 7, p. 747-759 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

HE4 and eIF3a expression correlates with surgical outcome and overall survival in ovarian cancer patients with secondary cytoreduction

Luo, C. H., Zhao, M., Chen, X. Y., Shahabi, S., Qiang, W., Zeng, L., Wang, J. & Zhou, H. H., Jan 1 2018, In : Journal of Cancer. 9, 14, p. 2472-2479 8 p.

Research output: Contribution to journalArticle

Pumilio2 regulates synaptic plasticity via translational repression of synaptic receptors in mice

Dong, H., Zhu, M., Meng, L., Ding, Y., Yang, D., Zhang, S., Qiang, W., Fisher, D. W. & Xu, E. Y., Aug 14 2018, In : Oncotarget. 9, 63, p. 32134-32148 15 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Baicalein Induces Beclin 1- and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells

Wang, Y. F., Xu, Y. L., Tang, Z. H., Li, T., Zhang, L. L., Chen, X., Lu, J. H., Leung, C. H., Ma, D. L., Qiang, W. A., Wang, Y. T. & Lu, J. J., Jan 1 2017, In : American Journal of Chinese Medicine. 45, 1, p. 123-136 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models

Ugolkov, A., Qiang, W., Bondarenko, G., Procissi, D., Gaisina, I., James, C. D., Chandler, J., Kozikowski, A., Gunosewoyo, H., O'Halloran, T., Raizer, J. & Mazar, A. P., Aug 2017, In : Translational Oncology. 10, 4, p. 669-678 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro

Zhong, Z. F., Tan, W., Tian, K., Yu, H., Qiang, W. A. & Wang, Y. T., Apr 2017, In : Oncology reports. 37, 4, p. 2016-2024 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Furanodiene induces extrinsic and intrinsic apoptosis in doxorubicin-resistant MCF-7 breast cancer cells via NF-κB-independent mechanism

Zhong, Z. F., Yu, H. B., Wang, C. M., Qiang, W. A., Wang, S. P., Zhang, J. M., Yu, H., Cui, L., Wu, T., Li, D. Q. & Wang, Y. T., Sep 14 2017, In : Frontiers in Pharmacology. 8, SEP, 648.

Research output: Contribution to journalArticle

3 Scopus citations

Garcinone e induces apoptosis and inhibits migration and invasion in ovarian cancer cells

Xu, X. H., Liu, Q. Y., Li, T., Liu, J. L., Chen, X., Huang, L., Qiang, W. A., Chen, X., Wang, Y., Lin, L. G. & Lu, J. J., Dec 1 2017, In : Scientific reports. 7, 1, 10718.

Research output: Contribution to journalArticle

12 Scopus citations

Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells

Zhao, G., Wang, Q., Gu, Q., Qiang, W., Wei, J. J., Dong, P., Watari, H., Li, W. & Yue, J., Nov 1 2017, In : Oncotarget. 8, 55, p. 94666-94680 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Subtype-specific tumor-associated fibroblasts contribute to the pathogenesis of uterine leiomyoma

Wu, X., Serna, V. A., Thomas, J., Qiang, W., Blumenfeld, M. L. & Kurita, T., Dec 15 2017, In : Cancer Research. 77, 24, p. 6891-6901 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells

Chen, X., Wu, Q. S., Meng, F. C., Tang, Z. H., Chen, X., Lin, L. G., Chen, P., Qiang, W. A., Wang, Y. T., Zhang, Q. W. & Lu, J. J., Dec 1 2016, In : Phytomedicine. 23, 13, p. 1555-1565 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Furanodiene alters mitochondrial function in doxorubicin-resistant MCF-7 human breast cancer cells in an AMPK-dependent manner

Zhong, Z. F., Tan, W., Qiang, W. W., Scofield, V. L., Tian, K., Wang, C. M., Qiang, W. A. & Wang, Y. T., Jan 1 2016, In : Molecular bioSystems. 12, 5, p. 1626-1637 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Furanodiene enhances the anti-cancer effects of doxorubicin on ERα-negative breast cancer cells in vitro

Zhong, Z. F., Qiang, W. A., Wang, C. M., Tan, W. & Wang, Y. T., Mar 5 2016, In : European Journal of Pharmacology. 774, p. 10-19 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Halofuginone suppresses growth of human uterine leiomyoma cells in a mouse xenograft model

Koohestani, F., Qiang, W., MacNeill, A. L., Druschitz, S. A., Serna, V. A., Adur, M., Kurita, T. & Nowak, R. A., Jan 1 2016, In : Human Reproduction. 31, 7, p. 1540-1551 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma

Dong, R., Qiang, W., Guo, H., Xu, X., Kim, J. J., Mazar, A., Kong, B. & Wei, J. J., Sep 21 2016, In : Journal of Hematology and Oncology. 9, 1, 92.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Anti-proliferative activity and cell cycle arrest induced by evodiamine on paclitaxel-sensitive and -resistant human ovarian cancer cells

Zhong, Z. F., Tan, W., Wang, S. P., Qiang, W. A. & Wang, Y. T., Nov 10 2015, In : Scientific reports. 5, 16415.

Research output: Contribution to journalArticle

30 Scopus citations

Human uterine leiomyoma stem/progenitor cells expressing CD34 and CD49b initiate tumors in vivo

Yin, P., Ono, M., Moravek, M. B., Coon, J. S. V., Navarro, A., Monsivais, D., Dyson, M. T., Druschitz, S. A., Malpani, S. S., Serna, V. A., Qiang, W., Chakravarti, D., Julie Kim, J. & Bulun, S. E., Apr 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 4, p. E601-E606

Research output: Contribution to journalArticle

32 Scopus citations

Role of miR-182 in response to oxidative stress in the cell fate of human fallopian tube epithelial cells

Liu, Y., Qiang, W., Xu, X., Dong, R., Karst, A. M., Liu, Z., Kong, B., Drapkin, R. I. & Wei, J. J., Jan 1 2015, In : Oncotarget. 6, 36, p. 38983-38998 16 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Anti-miR182 reduces ovarian cancer burden, invasion, and metastasis: An in vivo study in orthotopic xenografts of nude mice

Xu, X., Ayub, B., Liu, Z., Serna, V. A., Qiang, W., Liu, Y., Hernando, E., Zabludoff, S., Kurita, T., Kong, B. & Wei, J. J., Jul 2014, In : Molecular cancer therapeutics. 13, 7, p. 1729-1739 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Down-regulation of miR-29b is essential for pathogenesis of uterine leiomyoma

Qiang, W., Liu, Z., Serna, V. A., Druschitz, S. A., Liu, Y., Espona-Fiedler, M., Wei, J. J. & Kurita, T., Mar 1 2014, In : Endocrinology. 155, 3, p. 663-669 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Inactivation of AKT induces cellular senescence in uterine leiomyoma

Xu, X., Lu, Z., Qiang, W., Vidimar, V., Kong, B., Kim, J. J. & Wei, J-J., Apr 1 2014, In : Endocrinology. 155, 4, p. 1510-1519 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

MED12 and HMGA2 mutations: Two independent genetic events in uterine leiomyoma and leiomyosarcoma

Bertsch, E., Qiang, W., Zhang, Q., Espona-Fiedler, M., Druschitz, S., Liu, Y., Mittal, K., Kong, B., Kurita, T. & Wei, J. J., Aug 2014, In : Modern Pathology. 27, 8, p. 1144-1153 10 p.

Research output: Contribution to journalArticle

77 Scopus citations

Molecular analyses of 6 different types of uterine smooth muscle tumors: Emphasis in atypical leiomyoma

Zhang, Q., Ubago, J., Li, L., Guo, H., Liu, Y., Qiang, W., Kim, J. J., Kong, B. & Wei, J. J., Jan 1 2014, In : Cancer. 120, 20, p. 3165-3177 13 p.

Research output: Contribution to journalArticle

34 Scopus citations
2013

MK-2206, an AKT inhibitor, promotes caspase-independent cell death and inhibits leiomyoma growth

Sefton, E. C., Qiang, W., Serna, V., Kurita, T., Wei, J. J., Chakravarti, D. & Kim, J. J., Nov 1 2013, In : Endocrinology. 154, 11, p. 4046-4057 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

Ono, M., Yin, P., Navarro, A., Moravek, M. B., Coon V, J. S., Druschitz, S. A., Serna, V. A., Qiang, W., Brooks, D. C., Malpani, S. S., Ma, J., Ercan, C. M., Mittal, N., Monsivais, D., Dyson, M. T., Yemelyanov, A., Maruyama, T., Chakravarti, D., Kim, J. J., Kurita, T. & 2 others, Gottardi, C. J. & Bulun, S. E., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 17053-17058 6 p.

Research output: Contribution to journalArticle

77 Scopus citations
2012

Role of stem cells in human uterine leiomyoma growth

Ono, M., Qiang, W., Serna, V. A., Yin, P., Coon, J. S., Navarro, A., Monsivais, D., Kakinuma, T., Dyson, M., Druschitz, S., Unno, K., Kurita, T. & Bulun, S. E., May 3 2012, In : PloS one. 7, 5, e36935.

Research output: Contribution to journalArticle

85 Scopus citations
2006

Astrocytes survive chronic infection and cytopathic effects of the ts1 mutant of the retrovirus moloney murine leukemia virus by upregulation of antioxidant defenses

Qiang, W., Kuang, X., Liu, J., Liu, N., Scofield, V. L., Reid, A. J., Jiang, Y., Stoica, G., Lynn, W. S. & Wong, P. K. Y., Apr 1 2006, In : Journal of virology. 80, 7, p. 3273-3284 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

ATM controls c-Myc and DNA synthesis during postnatal thymocyte development through regulation of redox state

Yan, M., Zhu, C., Liu, N., Jiang, Y., Scofield, V. L., Riggs, P. K., Qiang, W., Lynn, W. S. & Wong, P. K. Y., Aug 15 2006, In : Free Radical Biology and Medicine. 41, 4, p. 640-648 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes

Liu, N., Scofield, V. L., Qiang, W., Yan, M., Kuang, X. & Wong, P. K. Y., May 10 2006, In : Virology. 348, 2, p. 398-405 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Retrovirus-induced oxidative stress with neuroimmunodegeneration is suppressed by antioxidant treatment with a refined monosodium α-luminol (Galavit)

Jiang, Y., Scofield, V. L., Yan, M., Qiang, W., Liu, N., Reid, A. J., Lynn, W. S. & Wong, P. K. Y., May 1 2006, In : Journal of Virology. 80, 9, p. 4557-4569 13 p.

Research output: Contribution to journalArticle

34 Scopus citations
2005

ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes

Liu, N., Stoica, G., Yan, M., Scofield, V. L., Qiang, W., Lynn, W. S. & Wong, P. K. Y., Dec 1 2005, In : Laboratory Investigation. 85, 12, p. 1471-1480 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Control of Atm-/- thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone

Kuang, X., Yan, M., Liu, N., Scofield, V. L., Qiang, W., Cahill, J., Lynn, W. S. & Wong, P. K. Y., Mar 1 2005, In : Cancer Chemotherapy and Pharmacology. 55, 3, p. 203-212 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
19 Scopus citations
2004

Activation of endoplasmic reticulum stress signaling pathway is associated with neuronal degeneration in MoMuLV-ts1-induced spongiform encephalomyelopathy

Kim, H. T., Waters, K., Stoica, G., Qiang, W., Liu, N., Scofield, V. L. & Wong, P. K. Y., Jul 1 2004, In : Laboratory Investigation. 84, 7, p. 816-827 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Activation of transcription factor Nrf-2 and its downstream targets in response to Moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes

Qiang, W., Cahill, J. M., Liu, J., Kuang, X., Liu, N., Scofield, V. L., Voorhees, J. R., Reid, A. J., Yan, M., Lynn, W. S. & Wong, P. K. Y., Nov 1 2004, In : Journal of virology. 78, 21, p. 11926-11938 13 p.

Research output: Contribution to journalArticle

69 Scopus citations

Possible involvement of both endoplasmic reticulum- and mitochondria-dependent pathways in MoMuLV-ts1-induced apoptosis in astrocytes

Liu, N., Kuang, X., Kim, H. T., Stoica, G., Qiang, W., Scofield, V. L. & Wong, P. K. Y., Jun 1 2004, In : Journal of neurovirology. 10, 3, p. 189-198 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
2002

Induction of p53 accumulation by Moloney murine leukemia virus-ts1 infection in astrocytes via activation of extracellular signal-regulated kinases 1/2

Kim, H. T., Tasca, S., Qiang, W., Wong, P. K. Y. & Stoica, G., Jan 1 2002, In : Laboratory Investigation. 82, 6, p. 693-702 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Prevention of thymic lymphoma development in Atm-/- mice by dexamethasone

Yan, M., Kuang, X., Qiang, W., Shen, J., Claypool, K., Lynn, W. S. & Wong, P. K. Y., Sep 15 2002, In : Cancer Research. 62, 18, p. 5153-5157 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

The effect of A1015 on DNA synthesis of D-galactosamine damaged mice hepatotoxicity

Liu, B. C., Qiang, W. A. & Wang, Y. S., Jan 1 2002, In : Chinese Pharmacological Bulletin. 18, 4, p. 441-443 3 p.

Research output: Contribution to journalArticle

The peroxisome proliferator phenylbutyric acid (PBA) protects astrocytes from ts1 MoMuLV-induced oxidative cell death

Liu, N., Qiang, W., Kuang, X., Thuillier, P., Lynn, W. S. & Wong, P. K. Y., Aug 1 2002, In : Journal of NeuroVirology. 8, 4, p. 318-325 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
2001

Enhanced proteolysis of IκBα and IκBβ proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: A potential mechanism of NF-κB activation

Kim, H. T., Qiang, W., Wong, P. K. Y. & Stoica, G., Nov 20 2001, In : Journal of NeuroVirology. 7, 5, p. 466-475 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

The ataxia-telangiectasia gene product may modulate DNA turnover and control cell fate by regulating cellular redox in lymphocytes

Yan, M., Qiang, W., Liu, N., Shen, J., Lynn, W. S. & Wong, P. K. Y., May 24 2001, In : FASEB Journal. 15, 7, p. 1132-1138 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2000

Constitutive and inducible nitric oxide synthases after dynorphin-induced spinal cord injury

Hu, W. H., Qiang, W. A., Li, F., Liu, N., Wang, G. Q., Wang, H. Y., Wan, X. S. T., Liao, W. H., Liu, J. S. & Jen, M. F., Jan 1 2000, In : Journal of chemical neuroanatomy. 17, 4, p. 183-197 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Effects of high dose of dynorphin on NMDA receptor and NOS activities in spinal cord of rats

Qiang, W., Sun, L., Hu, W., Zuo, P., Ren, M. & Liu, J., Apr 2000, In : Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 22, 2, p. 134-138 5 p.

Research output: Contribution to journalArticle

Polyactin A induced nitro oxide from mice macrophages and its antitumor activity

Xiaokang, L., Liming, Z., Wen'an, Q. & Yusheng, W., Jan 1 2000, In : Chinese Journal of Antibiotics. 25, 1, p. 62-63 2 p.

Research output: Contribution to journalArticle

1999

Dual role for nitric oxide in dynorphin spinal neurotoxicity

Hu, W. H., Li, F., Qiang, W. A., Liu, N., Wang, G. Q., Xiao, J., Liu, J. S., Liao, W. H. & Jen, M. F., Jan 1999, In : Journal of neurotrauma. 16, 1, p. 85-98 14 p.

Research output: Contribution to journalArticle

18 Scopus citations