William A Muller

  • 15135 Citations
1980 …2020

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2020

Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro

Nishihara, H., Soldati, S., Mossu, A., Rosito, M., Rudolph, H., Muller, W. A., Latorre, D., Sallusto, F., Sospedra, M., Martin, R., Ishikawa, H., Tenenbaum, T., Schroten, H., Gosselet, F. & Engelhardt, B., Feb 3 2020, In : Fluids and barriers of the CNS. 17, 1, 3.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Return of Individual Research Results: A Guide for Biomedical Researchers Utilizing Human Biospecimens

Sobel, M. E., Dreyfus, J. C., Dillehay McKillip, K., Kolarcik, C., Muller, W. A., Scott, M. J., Siegal, G. P., Wadosky, K. & O'Leary, T. J., May 2020, In : American Journal of Pathology. 190, 5, p. 918-933 16 p.

Research output: Contribution to journalArticle

Open Access

Spinocerebellar Ataxia Type 3: A Case Report and Literature Review

McCord, M. R., Bigio, E. H., Kam, K. L., Fischer, V., Obeidin, F., White, C. L., Brat, D. J., Muller, W. A. & Mao, Q., Jun 1 2020, In : Journal of neuropathology and experimental neurology. 79, 6, p. 641-646 6 p.

Research output: Contribution to journalArticle

2019

Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis

Sullivan, D. P., Dalal, P. J., Jaulin, F., Sacks, D. B., Kreitzer, G. & Muller, W. A., Nov 1 2019, In : Journal of Experimental Medicine. 216, 11, p. 2582-2601 20 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Longitudinal deep-brain imaging in mouse using visible-light optical coherence tomography through chronic microprism cranial window

Beckmann, L., Zhang, X., Nadkarni, N. A., Cai, Z., Batra, A., Sullivan, D. P., Muller, W. A., Sun, C., Kuranov, R. & Zhang, H. F., Oct 1 2019, In : Biomedical Optics Express. 10, 10, p. 5235-5250 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

PECAM-1 stabilizes blood-brain barrier integrity and favors paracellular T-cell diapedesis across the blood-brain barrier during neuroinflammation

Wimmer, I., Tietz, S., Nishihara, H., Deutsch, U., Sallusto, F., Gosselet, F., Lyck, R., Muller, W. A., Lassmann, H. & Engelhardt, B., Jan 1 2019, In : Frontiers in immunology. 10, APR, 711.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response

Klomp, J. E., Shaaya, M., Matsche, J., Rebiai, R., Aaron, J. S., Collins, K. B., Huyot, V., Gonzalez, A. M., Muller, W. A., Chew, T. L., Malik, A. B. & Karginov, A. V., Aug 15 2019, In : Cell Chemical Biology. 26, 8, p. 1081-1094.e6

Research output: Contribution to journalArticle

1 Scopus citations
2018
2 Scopus citations
2017

Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses

Early, M., Schroeder, W. G., Unnithan, R., Gilchrist, J. M., Muller, W. A. & Schenkel, A., 2017, In : PeerJ. 2017, 7, e3555.

Research output: Contribution to journalArticle

2 Scopus citations

Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking

Randolph, G. J., Beaulieu, S., Lebecque, S., Steinman, R. M. & Muller, W. A., Jun 1 2017, In : Journal of Immunology. 198, 11, p. 4191-4194 4 p.

Research output: Contribution to journalArticle

Loss of mDia1 causes neutropenia via attenuated CD11b endocytosis and increased neutrophil adhesion to the endothelium

Mei, Y., Feng, G., Rahimi, N., Zhao, B., Zhang, J., Cao, L., Yang, J., Gao, J., Chen, Y., Sumagin, R., Muller, W. A., Zhang, L. & Ji, P., Sep 12 2017, In : Blood Advances. 1, 20, p. 1650-1656 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

MerTK cleavage on resident cardiac macrophages compromises repair after myocardial ischemia reperfusion injury

DeBerge, M., Yeap, X. Y., Dehn, S., Zhang, S., Grigoryeva, L., Misener, S., Procissi, D., Zhou, X., Lee, D. C., Muller, W. A., Luo, X., Rothlin, C., Tabas, I. & Thorp, E. B., Sep 1 2017, In : Circulation research. 121, 8, p. 930-940 11 p.

Research output: Contribution to journalArticle

44 Scopus citations
2016
7 Scopus citations

A Unique Role for Endothelial Cell Kinesin Light Chain 1, Variant 1 in Leukocyte Transendothelial Migration

Cyrus, B. F. & Muller, W. A., May 1 2016, In : American Journal of Pathology. 186, 5, p. 1375-1386 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cutting edge: CD99 is a novel therapeutic target for control of T cell-mediated central nervous system autoimmune disease

Winger, R. C., Harp, C. T., Chiang, M. Y., Sullivan, D. P., Watson, R. L., Weber, E. W., Podoji, J. R., Miller, S. D. & Muller, W. A., Feb 15 2016, In : Journal of Immunology. 196, 4, p. 1443-1448 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
7 Scopus citations
2015

CD99-like 2 (CD99L2)-deficient mice are defective in the acute inflammatory response

Rutledge, N. S., Weber, E. W., Winger, R., Tourtellotte, W. G., Park, S. H. & Muller, W. A., Dec 1 2015, In : Experimental and Molecular Pathology. 99, 3, p. 455-459 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration

Watson, R. L., Buck, J., Levin, L. R., Winger, R. C., Wang, J., Arase, H. & Muller, W. A., Jun 29 2015, In : Journal of Experimental Medicine. 212, 7, p. 1021-1041 21 p.

Research output: Contribution to journalArticle

48 Scopus citations

Monocytes from HIV-infected individuals show impaired cholesterol efflux and increased foam cell formation after transendothelial migration

Maisa, A., Hearps, A. C., Angelovich, T. A., Pereira, C. F., Zhou, J., Shi, M. D. Y., Palmer, C. S., Muller, W. A., Crowe, S. M. & Jaworowski, A., Jul 31 2015, In : AIDS. 29, 12, p. 1445-1457 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

Segregation of VE-cadherin from the LBRC depends on the ectodomain sequence required for homophilic adhesion

Feng, G., Sullivan, D. P., Han, F. & Muller, W. A., 2015, In : Journal of cell science. 128, 3, p. 576-588 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response

Weber, E. W., Han, F., Tauseef, M., Birnbaumer, L., Mehta, D. & Muller, W. A., Oct 19 2015, In : Journal of Experimental Medicine. 212, 11, p. 1883-1899 17 p.

Research output: Contribution to journalArticle

55 Scopus citations
2014

Blocking monocyte transmigration in in vitro system by a human antibody scFv anti-CD99. Efficient large scale purification from periplasmic inclusion bodies in E. coli expression system

Moricoli, D., Muller, W. A., Carbonella, D. C., Balducci, M. C., Dominici, S., Watson, R., Fiori, V., Weber, E., Cianfriglia, M., Scotlandi, K. & Magnani, M., Jun 2014, In : Journal of Immunological Methods. 408, p. 35-45 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

How endothelial cells regulate transmigration of leukocytes in the inflammatory response

Muller, W. A., Jan 1 2014, In : American Journal of Pathology. 184, 4, p. 886-896 11 p.

Research output: Contribution to journalArticle

72 Scopus citations

Isolation of the lateral border recycling compartment using a diaminobenzidine-induced density shift

Sullivan, D. P., Rüffer, C. & Muller, W. A., Sep 2014, In : Traffic. 15, 9, p. 1016-1029 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Microhemorrhage is an early event in the pulmonary fibrotic disease of PECAM-1 deficient FVB/n mice

Lishnevsky, M., Young, L. C., Woods, S. J., Groshong, S. D., Basaraba, R. J., Gilchrist, J. M., Higgins, D. M., Gonzalez-Juarrero, M., Bass, T. A., Muller, W. A. & Schenkel, A. R., Aug 2014, In : Experimental and Molecular Pathology. 97, 1, p. 128-136 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier

Winger, R. C., Koblinski, J. E., Kanda, T., Ransohoff, R. M. & Muller, W. A., Sep 1 2014, In : Journal of Immunology. 193, 5, p. 2427-2437 11 p.

Research output: Contribution to journalArticle

52 Scopus citations
2013

Absence of platelet endothelial cell adhesion molecule 1, PECAM-1/ CD31, in vivo increases resistance to salmonella enterica serovar typhimurium in mice

Lovelace, M. D., Yap, M. L., Yip, J., Muller, W., Wijburg, O. & Jackson, D. E., Jun 2013, In : Infection and immunity. 81, 6, p. 1952-1963 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Endothelial transmigration by trypanosoma cruzi

Coates, B. M., Sullivan, D. P., Makanji, M. Y., Du, N. Y., Olson, C. L., Muller, W. A., Engman, D. M. & Epting, C. L., Dec 2 2013, In : PloS one. 8, 12, e81187.

Research output: Contribution to journalArticle

7 Scopus citations

Poliovirus receptor (CD155) regulates a step in transendothelial migration between PECAM and CD99

Sullivan, D. P., Seidman, M. A. & Muller, W. A., Mar 1 2013, In : American Journal of Pathology. 182, 3, p. 1031-1042 12 p.

Research output: Contribution to journalArticle

40 Scopus citations
2012

Endothelial cell activation promotes foam cell formation by monocytes following transendothelial migration in an in vitro model

Westhorpe, C. L. V., Dufour, E. M., Maisa, A., Jaworowski, A., Crowe, S. M. & Muller, W. A., Oct 1 2012, In : Experimental and Molecular Pathology. 93, 2, p. 220-226 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration

Liu, G., Place, A. T., Chen, Z., Brovkovych, V. M., Vogel, S. M., Muller, W. A., Skidgel, R. A., Malik, A. B. & Minshall, R. D., Aug 30 2012, In : Blood. 120, 9, p. 1942-1952 11 p.

Research output: Contribution to journalArticle

61 Scopus citations
2011

HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes

Wu, J., Liu, Z., Shao, C., Gong, Y., Hernando, E., Lee, P., Narita, M., Muller, W., Liu, J. & Wei, J. J., Jan 15 2011, In : Cancer Research. 71, 2, p. 349-359 11 p.

Research output: Contribution to journalArticle

115 Scopus citations

In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates

Jung, K. C., Park, C. G., Jeon, Y. K., Park, H. J., Ban, Y. L., Min, H. S., Kim, E. J., Kim, J. H., Kang, B. H., Park, S. P., Bae, Y., Yoon, I. H., Kim, Y. H., Lee, J. I., Kim, J. S., Shin, J. S., Yang, J., Kim, S. J., Rostlund, E., Muller, W. A. & 1 others, Park, S. H., Nov 21 2011, In : Journal of Experimental Medicine. 208, 12, p. 2477-2488 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Mechanisms of leukocyte transendothelial migration

Muller, W. A., Feb 28 2011, In : Annual Review of Pathology: Mechanisms of Disease. 6, p. 323-344 22 p.

Research output: Contribution to journalArticle

333 Scopus citations

Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity

Privratsky, J. R., Paddock, C. M., Florey, O., Newman, D. K., Muller, W. A. & Newman, P. J., May 1 2011, In : Journal of cell science. 124, 9, p. 1477-1485 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Remembering Ralph Steinman.

Banchereau, J., Cohn, F., Inaba, K., Muller, B., Mellman, I., Nathan, C., Nussenzweig, M., O'Garra, A., Seder, B., Schuler, G. & Sher, A., Nov 21 2011, In : The Journal of experimental medicine. 208, 12, p. 2343-2347 5 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2010
9 Scopus citations

Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins block distinct steps in transendothelial migration of effector memory CD4+ T cells by targeting different endothelial proteins

Manes, T. D., Hoer, S., Muller, W. A., Lehner, P. J. & Pober, J. S., May 1 2010, In : Journal of Immunology. 184, 9, p. 5186-5192 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Phosphorylation of leukocyte PECAM and its association with detergent-resistant membranes regulate transendothelial migration

Florey, O., Durgan, J. & Muller, W., Aug 1 2010, In : Journal of Immunology. 185, 3, p. 1878-1886 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2009

A novel and critical role for tyrosine 663 in platelet endothelial cell adhesion molecule-1 trafficking and transendothelial migration

Dasgupta, B., Dufour, E., Mamdouh, Z. & Muller, W. A., Apr 15 2009, In : Journal of Immunology. 182, 8, p. 5041-5051 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Effects of HIV-1 infection in vitro on transendothelial migration by monocytes and monocyte-derived macrophages

Westhorpe, C. L. V., Zhou, J., Webster, N. L., Kalionis, B., Lewin, S. R., Jaworowski, A., Muller, W. A. & Crowe, S. M., Jun 1 2009, In : Journal of Leukocyte Biology. 85, 6, p. 1027-1035 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Non-invasive diagnosis of early pulmonary disease in PECAM-deficient mice using infrared pulse oximetry

Early, M. A., Lishnevsky, M., Gilchrist, J. M., Higgins, D. M., Orme, I. M., Muller, W. A., Gonzalez-Juarerro, M. & Schenkel, A. R., Oct 1 2009, In : Experimental and Molecular Pathology. 87, 2, p. 152-158 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

PECAM-independent thioglycollate peritonitis is associated with a locus on murine chromosome 2

Seidman, M. A., Chew, T. W., Schenkel, A. R. & Muller, W. A., Jan 30 2009, In : PLoS One. 4, 1, e4316.

Research output: Contribution to journalArticle

16 Scopus citations

Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartment

Mamdouh, Z., Mikhailov, A. & Muller, W. A., Nov 23 2009, In : Journal of Experimental Medicine. 206, 12, p. 2795-2808 14 p.

Research output: Contribution to journalArticle

128 Scopus citations
2008

CD99 is essential for leukocyte diapedesis in vivo

Dufour, E. M., Deroche, A., Bae, Y. & Muller, W. A., 2008, In : Cell Communication and Adhesion. 15, 4, p. 351-363 13 p.

Research output: Contribution to journalArticle

44 Scopus citations
18 Scopus citations

Leukocyte transmigration requires kinesin-mediated microtubule-dependent membrane trafficking from the lateral border recycling compartment

Mamdouh, Z., Kreitzer, G. E. & Muller, W. A., Apr 14 2008, In : Journal of Experimental Medicine. 205, 4, p. 951-966 16 p.

Research output: Contribution to journalArticle

82 Scopus citations

Tonsilar NK cells restrict B cell transformation by the epstein-barr virus via IFN-γ

Strowig, T., Brilot, F., Arrey, F., Bougras, G., Thomas, D., Muller, W. A. & Münz, C., Feb 2008, In : PLoS pathogens. 4, 2

Research output: Contribution to journalArticle

85 Scopus citations
2007

CD99 is a key mediator of the transendothelial migration of neutrophils

Lou, O., Alcaide, P., Luscinskas, F. W. & Muller, W. A., Jan 15 2007, In : Journal of Immunology. 178, 2, p. 1136-1143 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms

Reinke, E. K., Lee, J., Zozulya, A., Karman, J., Muller, W. A., Sandor, M. & Fabry, Z., May 1 2007, In : Journal of Neuroimmunology. 186, 1-2, p. 86-93 8 p.

Research output: Contribution to journalArticle

14 Scopus citations