Grants per year
Personal profile
Research Interests
My clinical domain is breast cancer management. My clinical research interest focuses on the development of novel therapies for the treatment of breast cancer. Clinical trials focusing on precision medicine for defining the right therapy, for the right patient at the right time is our goal. To that end, molecular interogation of breast tumors are leading to novel trial design that will hopefully translate into better outcomes for our patients. In conjuction with the developmental therapeutics program, novel agents are being incorporated into clinical trials for patients with both early and late stage disease.
Certifications and Licenses
Internal Medicine | |
Medical Oncology |
Training Experience
1986 | Residency, Michael Reese Medical Center |
1990 | Fellowship, University of Chicago Hospitals |
Education/Academic qualification
MD, University of Illinois at Chicago
… → 1982
Medicine, MD, University of Illinois at Chicago
… → 1982
Research interests
- Breast Cancer
- Chemotherapy
- Clinical Research
- Drug Discovery
- Drugs (clinical pharmacology)
- Genomic Medicine/Personalized Medicine
- Medical Education
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Network
Grants
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Prot #CT7001_001: A Modular, Multipart, Multi-arm, Open-label, Phase 1/2a Study to Evaluate the Safety and Tolerability of CT7001 Alone and in Combination with Anti-Cancer Treatments in Patients with Advanced Malignancies
Emas Pharma Limited, Carrick Therapeutics Ltd
10/15/20 → 10/15/23
Project: Research project
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Prot #CBYL719G12301: EPIK-B2: A Two Part, Phase III, Multicenter, Randomized (1:1), Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Alpelisib (BYL719) in Combination with Trastuzumab and Pertuzumab as Maintenance Therapy in Pat
Novartis Pharmaceuticals Corporation
7/1/20 → 12/31/24
Project: Research project
Research Output
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Phase III, randomized study of dual human epidermal growth factor receptor 2 (HER2) blockade with lapatinib plus trastuzumab in combination with an aromatase inhibitor in postmenopausal women with HER2-positive, hormone receptor–positive metastatic breast cancer: Updated results of alternative
Johnston, S. R. D., Hegg, R., Im, S. A., Park, I. H., Burdaeva, O., Kurteva, G., Press, M. F., Tjulandin, S., Iwata, H., Simon, S. D., Kenny, S., Sarp, S., Izquierdo, M. A., Williams, L. S. & Gradishar, W. J., Jan 1 2021, In: Journal of Clinical Oncology. 39, 1, p. 79-89 11 p.Research output: Contribution to journal › Article › peer-review
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Predictors and outcomes in breast cancer patients who did or did not pursue fertility preservation
Moravek, M. B., Confino, R., Lawson, A. K., Smith, K. N., Kazer, R., Klock, S. M., Gradishar, W. J., Jeruss, J. S. & Pavone, M. E., 2021, (Accepted/In press) In: Breast Cancer Research and Treatment.Research output: Contribution to journal › Article › peer-review
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Understanding the organ tropism of metastatic breast cancer through the combination of liquid biopsy tools
Gerratana, L., Davis, A. A., Polano, M., Zhang, Q., Shah, A. N., Lin, C., Basile, D., Toffoli, G., Wehbe, F., Puglisi, F., Behdad, A., Platanias, L. C., Gradishar, W. J. & Cristofanilli, M., Jan 2021, In: European Journal of Cancer. 143, p. 147-157 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Addressing Fertility: an Essential Aspect of Comprehensive Care for Young Patients with Breast Cancer
Shah, A. N., Luck, M., Goldman, K. & Gradishar, W., Dec 2020, In: Current Breast Cancer Reports. 12, 4, p. 381-390 10 p.Research output: Contribution to journal › Review article › peer-review
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Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis
Telli, M. L., Chu, C., Badve, S. S., Vinayak, S., Silver, D. P., Isakoff, S. J., Kaklamani, V., Gradishar, W., Stearns, V., Connolly, R. M., Ford, J. M., Gruber, J. J., Adams, S., Garber, J., Tung, N., Neff, C., Bernhisel, R., Timms, K. M. & Richardson, A. L., Jun 1 2020, In: Clinical Cancer Research. 26, 11, p. 2704-2710 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations