William J Gradishar

  • 12981 Citations
1988 …2020

Research output per year

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Personal profile

Research Interests

My clinical domain is breast cancer management. My clinical research interest focuses on the development of novel therapies for the treatment of breast cancer. Clinical trials focusing on precision medicine for defining the right therapy, for the right patient at the right time is our goal. To that end, molecular interogation of breast tumors are leading to novel trial design that will hopefully translate into better outcomes for our patients. In conjuction with the developmental therapeutics program, novel agents are being incorporated into clinical trials for patients with both early and late stage disease.

Certifications and Licenses

Internal Medicine
Medical Oncology

Training Experience

1986Residency, Michael Reese Medical Center
1990Fellowship, University of Chicago Hospitals

Education/Academic qualification

MD, University of Illinois at Chicago

… → 1982

Research interests

  • Breast Cancer
  • Chemotherapy
  • Clinical Research
  • Drug Discovery
  • Drugs (clinical pharmacology)
  • Genomic Medicine/Personalized Medicine
  • Medical Education

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Grants

Research Output

Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis

Telli, M. L., Chu, C., Badve, S. S., Vinayak, S., Silver, D. P., Isakoff, S. J., Kaklamani, V., Gradishar, W., Stearns, V., Connolly, R. M., Ford, J. M., Gruber, J. J., Adams, S., Garber, J., Tung, N., Neff, C., Bernhisel, R., Timms, K. M. & Richardson, A. L., Jun 1 2020, In : Clinical Cancer Research. 26, 11, p. 2704-2710 7 p.

Research output: Contribution to journalArticle

  • Breast Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology

    Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Agnese, D., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Krishnamurthy, J., Lyons, J., Marcom, P. K., Matro, J., Mayer, I. A., Moran, M. S. & 15 others, Mortimer, J., O'Regan, R. M., Patel, S. A., Pierce, L. J., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Stringer-Reasor, E. M., Telli, M. L., Ward, J. H., Young, J. S., Burns, J. L. & Kumar, R., Apr 1 2020, In : Journal of the National Comprehensive Cancer Network : JNCCN. 18, 4, p. 452-478 27 p.

    Research output: Contribution to journalArticle

    Open Access
  • 6 Scopus citations

    Evaluation of the 12-Gene Molecular Score and the 21-Gene Recurrence Score as Predictors of Response to Neo-adjuvant Chemotherapy in Estrogen Receptor-Positive, HER2-Negative Breast Cancer

    Soliman, H., Wagner, S., Flake, D. D., Robson, M., Schwartzberg, L., Sharma, P., Magliocco, A., Kronenwett, R., Lancaster, J. M., Lanchbury, J. S., Gutin, A. & Gradishar, W., Mar 1 2020, In : Annals of surgical oncology. 27, 3, p. 765-771 7 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Landscape of circulating tumour DNA in metastatic breast cancer

    Davis, A. A., Jacob, S., Gerratana, L., Shah, A. N., Wehbe, F., Katam, N., Zhang, Q., Flaum, L., Siziopikou, K. P., Platanias, L. C., Gradishar, W. J., Behdad, A. & Cristofanilli, M., Aug 2020, In : EBioMedicine. 58, 102914.

    Research output: Contribution to journalArticle

    Open Access
  • Novel Neoadjuvant Treatment Strategies for Triple-Negative Breast Cancer

    Davis, A. A. & Gradishar, W. J., May 13 2020, In : Oncology (Williston Park, N.Y.). 34, 5, p. 176-182 7 p.

    Research output: Contribution to journalArticle