William J Gradishar

  • 13146 Citations
1988 …2020

Research output per year

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Research Output

2020

Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis

Telli, M. L., Chu, C., Badve, S. S., Vinayak, S., Silver, D. P., Isakoff, S. J., Kaklamani, V., Gradishar, W., Stearns, V., Connolly, R. M., Ford, J. M., Gruber, J. J., Adams, S., Garber, J., Tung, N., Neff, C., Bernhisel, R., Timms, K. M. & Richardson, A. L., Jun 1 2020, In : Clinical Cancer Research. 26, 11, p. 2704-2710 7 p.

Research output: Contribution to journalArticle

Breast cancer, version 3.2020

Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Agnese, D., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Krishnamurthy, J., Lyons, J., Marcom, P. K., Matro, J., Mayer, I. A., Moran, M. S. & 15 others, Mortimer, J., O’Regan, R. M., Patel, S. A., Pierce, L. J., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Stringer-Reasor, E. M., Telli, M. L., Ward, J. H., Young, J. S., Burns, J. L. & Kumar, R., Apr 2020, In : JNCCN Journal of the National Comprehensive Cancer Network. 18, 4, p. 452-478 27 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Evaluation of the 12-Gene Molecular Score and the 21-Gene Recurrence Score as Predictors of Response to Neo-adjuvant Chemotherapy in Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Soliman, H., Wagner, S., Flake, D. D., Robson, M., Schwartzberg, L., Sharma, P., Magliocco, A., Kronenwett, R., Lancaster, J. M., Lanchbury, J. S., Gutin, A. & Gradishar, W., Mar 1 2020, In : Annals of surgical oncology. 27, 3, p. 765-771 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Landscape of circulating tumour DNA in metastatic breast cancer

Davis, A. A., Jacob, S., Gerratana, L., Shah, A. N., Wehbe, F., Katam, N., Zhang, Q., Flaum, L., Siziopikou, K. P., Platanias, L. C., Gradishar, W. J., Behdad, A. & Cristofanilli, M., Aug 2020, In : EBioMedicine. 58, 102914.

Research output: Contribution to journalArticle

Open Access

Novel Neoadjuvant Treatment Strategies for Triple-Negative Breast Cancer

Davis, A. A. & Gradishar, W. J., May 13 2020, In : Oncology (Williston Park, N.Y.). 34, 5, p. 176-182 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access

Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. the COVID-19 pandemic breast cancer consortium

Dietz, J. R., Moran, M. S., Isakoff, S. J., Kurtzman, S. H., Willey, S. C., Burstein, H. J., Bleicher, R. J., Lyons, J. A., Sarantou, T., Baron, P. L., Stevens, R. E., Boolbol, S. K., Anderson, B. O., Shulman, L. N., Gradishar, W. J., Monticciolo, D. L., Plecha, D. M., Nelson, H. & Yao, K. A., Jun 1 2020, In : Breast Cancer Research and Treatment. 181, 3, p. 487-497 11 p.

Research output: Contribution to journalEditorial

Open Access
28 Scopus citations

Selective progesterone receptor modulators in early-stage breast cancer: A randomized, placebo-controlled phase II window-of-opportunity trial using telapristone acetate

Lee, O., Sullivan, M. E., Xu, Y., Rogers, C., Muzzio, M., Helenowski, I., Shidfar, A., Zeng, Z., Singhal, H., Jovanovic, B., Hansen, N., Bethke, K. P., Gann, P. H., Gradishar, W., Kim, J. J., Clare, S. E. & Khan, S. A., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2019

A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy

Zhou, Z., Feng, Z., Hu, D., Yang, P., Gur, M., Bahar, I., Cristofanilli, M., Gradishar, W. J., Xie, X. Q. & Wan, Y., Jun 2019, In : EBioMedicine. 44, p. 98-111 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Are Biosimilars the Future of Oncology and Haematology?

Zinzani, P. L., Dreyling, M., Gradishar, W., Andre, M., Esteva, F. J., Boulos, S., González Barca, E. & Curigliano, G., Oct 1 2019, In : Drugs. 79, 15, p. 1609-1624 16 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
2 Scopus citations

Breast cancer, version 3.2018 featured updates to the NCCN guidelines

Goetz, M. P., Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Farrar, W. B., Giordano, S. H., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., Moran, M. S., Mortimer, J., O’Regan, R. M. & 13 others, Patel, S. A., Pierce, L. J., Reed, E. C., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Telli, M. L., Ward, J. H., Young, J. S., Shead, D. A. & Kumar, R., Feb 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Current state of clinical trials in breast cancer brain metastases

Fares, J., Kanojia, D., Cordero, A., Rashidi, A., Miska, J., Schwartz, C. W., Savchuk, S., Ahmed, A. U., Balyasnikova, I. V., Cristofanilli, M., Gradishar, W. J. & Lesniak, M. S., Sep 20 2019, In : Neuro-Oncology Practice. 6, 5, p. 392-401 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Feasibility and acceptability of intensive longitudinal data collection of activity and patient-reported outcomes during chemotherapy for breast cancer

Solk, P., Gavin, K., Fanning, J., Welch, W., Lloyd, G., Cottrell, A., Nielsen, A., Santa Maria, C. A., Gradishar, W., Khan, S. A., Kulkarni, S., Siddique, J. & Phillips, S. M., Dec 1 2019, In : Quality of Life Research. 28, 12, p. 3333-3346 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Innovating Cancer Care Delivery: the Example of the 4R Oncology Model for Colorectal Cancer Patients

Trosman, J., Weldon, C., Kircher, S., Gradishar, W. & Benson, A., Feb 1 2019, In : Current treatment options in oncology. 20, 2, 11.

Research output: Contribution to journalReview article

NCCN Guidelines Updates: Breast Cancer

Telli, M. L., Gradishar, W. J. & Ward, J. H., May 1 2019, In : Journal of the National Comprehensive Cancer Network : JNCCN. 17, 55, p. 552-555 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

Prediction of chemotherapy benefit by EndoPredict in patients with breast cancer who received adjuvant endocrine therapy plus chemotherapy or endocrine therapy alone

Sestak, I., Martín, M., Dubsky, P., Kronenwett, R., Rojo, F., Cuzick, J., Filipits, M., Ruiz, A., Gradishar, W., Soliman, H., Schwartzberg, L., Buus, R., Hlauschek, D., Rodríguez-Lescure, A. & Gnant, M., Jul 30 2019, In : Breast Cancer Research and Treatment. 176, 2, p. 377-386 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Prognostic role of serum thymidine kinase 1 activity in patients with hormone receptor–positive metastatic breast cancer: Analysis of the randomised phase III Evaluation of Faslodex versus Exemestane Clinical Trial (EFECT)

McCartney, A., Biagioni, C., Schiavon, G., Bergqvist, M., Mattsson, K., Migliaccio, I., Benelli, M., Romagnoli, D., Bonechi, M., Boccalini, G., Pestrin, M., Galardi, F., De Luca, F., Biganzoli, L., Piccart, M., Gradishar, W. J., Chia, S., Di Leo, A. & Malorni, L., Jun 2019, In : European Journal of Cancer. 114, p. 55-66 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Relationship of pathological features and a 21 gene expression assay in younger versus older women with node-negative endocrine receptor-positive breast cancer

Mutonga, M., Speedy, S., Rademaker, A., Liu, D., Uthe, R., Jain, S., Gradishar, W. J., Flaum, L. & Santa-Maria, C. A., Jul 15 2019, In : Breast Cancer Research and Treatment. 176, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

U.S. prevalence of endocrine therapy–naïve locally advanced or metastatic breast cancer

Nunes, A. P., Liang, C., Gradishar, W. J., Dalvi, T., Lewis, J., Jones, N., Green, E., Doherty, M. & Seeger, J. D., 2019, In : Current Oncology. 26, 2, p. e180-e187

Research output: Contribution to journalArticle

Open Access
2018

Adjuvant and neoadjuvant systemic therapies for early-stage breast cancer

Santa-Maria, C. A. & Gradishar, W. J., Jan 1 2018, The Breast: Comprehensive Management of Benign and Malignant Diseases. Elsevier Inc, p. 752-762.e4

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Adjuvant Anthracyclines in Breast Cancer: What Is Their Role?

Shah, A. N. & Gradishar, W. J., Aug 17 2018, In : The oncologist.

Research output: Contribution to journalArticle

4 Scopus citations

Advances in endocrine therapy for postmenopausal metastatic breast cancer

Flaum, L. E. & Gradishar, W. J., Jan 1 2018, Cancer Treatment and Research. Springer International Publishing, p. 141-154 14 p. (Cancer Treatment and Research; vol. 173).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer

Santa-Maria, C. A., Kato, T., Park, J. H., Kiyotani, K., Rademaker, A., Shah, A. N., Gross, L., Blanco, L. Z., Jain, S., Flaum, L., Tellez, C., Stein, R., Uthe, R., Gradishar, W. J., Cristofanilli, M., Nakamura, Y. & Giles, F. J., Apr 10 2018, In : Oncotarget. 9, 27, p. 18985-18996 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Cell-free DNA and circulating tumor cells: Comprehensive liquid biopsy analysis in advanced breast cancer

Rossi, G., Mu, Z., Rademaker, A. W., Austin, L. K., Strickland, K. S., Costa, R. L. B., Nagy, R. J., Zagonel, V., Taxter, T. J., Behdad, A., Wehbe, F. H., Platanias, L. C., Gradishar, W. J. & Cristofanilli, M., Feb 1 2018, In : Clinical Cancer Research. 24, 3, p. 560-568 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Clinical practice guidelines in oncology

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A., Elias, A. D., Farrar, W. B., Forero, A., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., McCormick, B., Moran, M. S., O’Regan, R. M., Patel, S. A. & 13 others, Pierce, L. J., Reed, E. C., Salerno, K. E., Schwartzberg, L. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Somlo, G., Telli, M. L., Ward, J. H., Kumar, R. & Shead, D. A., Mar 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 3, p. 310-320 11 p.

Research output: Contribution to journalArticle

118 Scopus citations

Do genomic assays provide the necessary confidence to de-escalate adjuvant therapy?

Costa, R. L. B. & Gradishar, W. J., Mar 10 2018, In : Journal of Clinical Oncology. 36, 8, p. 725-727 3 p.

Research output: Contribution to journalEditorial

Double-blind phase III trial of adjuvant chemotherapy withand without bevacizumab in patients with lymph node-positiveand high-risk lymph node-negative breast cancer (E5103)

Miller, K. D., O'Neill, A., Gradishar, W., Hobday, T. J., Goldstein, L. J., Mayer, I. A., Bloom, S., Brufsky, A. M., Tevaarwerk, A. J., Sparano, J. A., Le-Lindqwister, N. A., Hendricks, C. B., Northfelt, D. W., Dang, C. T. & Sledge, G. W., Sep 1 2018, In : Journal of Clinical Oncology. 36, 25, p. 2621-2629 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Enzalutamide for the treatment of androgen receptor-expressing triple-negative breast cancer

Traina, T. A., Miller, K., Yardley, D. A., Eakle, J., Schwartzberg, L. S., O'Shaughnessy, J., Gradishar, W., Schmid, P., Winer, E., Kelly, C., Nanda, R., Gucalp, A., Awada, A., Garcia-Estevez, L., Trudeau, M. E., Steinberg, J., Uppal, H., Tudor, I. C., Peterson, A. & Cortes, J., 2018, In : Journal of Clinical Oncology. 36, 9, p. 884-890 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Everolimus plus endocrine therapy for postmenopausal women with estrogen receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: A clinical trial

Royce, M., Bachelot, T., Villanueva, C., Özgüroglu, M., Azevedo, S. J., Cruz, F. M., Debled, M., Hegg, R., Toyama, T., Falkson, C., Jeong, J., Srimuninnimit, V., Gradishar, W. J., Arce, C., Ridolfi, A., Lin, C. & Cardoso, F., Jul 2018, In : JAMA Oncology. 4, 7, p. 977-984 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

From the Past to the Present: Insurer Coverage Frameworks for Next-Generation Tumor Sequencing

Trosman, J. R., Weldon, C. B., Gradishar, W. J., Benson III, A. B., Cristofanilli, M., Kurian, A. W., Ford, J. M., Balch, A., Watkins, J. & Phillips, K. A., Sep 2018, In : Value in Health. 21, 9, p. 1062-1068 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Inhibitors of tumor angiogenesis

Shah, A. N. & Gradishar, W. J., Jan 1 2018, Cancer Chemotherapy, Immunotherapy and Biotherapy: Principles and Practice, Sixth Edition. Wolters Kluwer Health, p. 440-466 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Locally advanced breast cancer

Costa, R., Hansen, N. M. & Gradishar, W. J., Jan 1 2018, The Breast: Comprehensive Management of Benign and Malignant Diseases. Elsevier Inc, p. 819-831.e6

Research output: Chapter in Book/Report/Conference proceedingChapter

Long-term outcomes in cancer patients who did or did not pursue fertility preservation

Moravek, M. B., Confino, R., Smith, K. N., Kazer, R. R., Klock, S. C., Lawson, A. K., Gradishar, W. J. & Pavone, M. E., Feb 2018, In : Fertility and Sterility. 109, 2, p. 349-355 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Male breast cancer

Jain, S. & Gradishar, W. J., Jan 1 2018, The Breast: Comprehensive Management of Benign and Malignant Diseases. Elsevier Inc, p. 974-980.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

NCCN guidelines updates: Breast cancer

Giordano, S. H., Elias, A. D. & Gradishar, W. J., May 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 5S, p. 605-610 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Phase III, Randomized study of dual human epidermal growth factor receptor 2 (HER2) blockade with lapatinib plus trastuzumab in combination with an aromatase inhibitor in postmenopausal women with HER2-positive, hormone receptor-positive metastatic breast cancer: ALTERNATIVE

Johnston, S. R. D., Hegg, R., Im, S. A., Park, I. H., Burdaeva, O., Kurteva, G., Press, M. F., Tjulandin, S., Iwata, H., Simon, S. D., Kenny, S., Sarp, S., Izquierdo, M. A., Williams, L. S. & Gradishar, W. J., Mar 10 2018, In : Journal of Clinical Oncology. 36, 8, p. 741-748 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
23 Scopus citations

Predicting expected absolute chemotherapy treatment benefit in women with early-stage breast cancer using endopredict, an integrated 12-gene clinicomolecular assay

Soliman, H., Flake, D. D., Magliocco, A., Robson, M., Schwartzberg, L., Sharma, P., Brown, K., Wehnelt, S., Kronenwett, R., Gutin, A., Lancaster, J., Cuzick, J. & Gradishar, W., 2018, In : JCO Precision Oncology. 2

Research output: Contribution to journalArticle

Open Access

Preface

Bland, K. I., Copeland, E. M., Klimberg, V. S. & Gradishar, W. J., 2018, The Breast: Comprehensive Management of Benign and Malignant Diseases. Elsevier Inc, p. xv-xvi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

2 Scopus citations

Risk factors for the development of paclitaxel-induced neuropathy in breast cancer patients

Robertson, J., Raizer, J., Hodges, J. S., Gradishar, W. & Allen, J. A., Jun 2018, In : Journal of the Peripheral Nervous System. 23, 2, p. 129-133 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Settings-based efficacy comparison of trastuzumab biosimilars in breast cancer: A systematic literature review

Rugo, H. S., Curigliano, G., Cardoso, F., Gradishar, W. J., Pegram, M., Barrios, C. H. H., Cortes Castan, J., Pennella, E. & Muniz, R., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii104

Research output: Contribution to journalArticle

Open Access

Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review

Costa, R. L. B., Han, H. S. & Gradishar, W. J., Jun 1 2018, In : Breast Cancer Research and Treatment. 169, 3, p. 397-406 10 p.

Research output: Contribution to journalReview article

95 Scopus citations

The National Physicians Cooperative: Transforming fertility management in the cancer setting and beyond

Smith, B. M., Duncan, F. E., Ataman, L., Smith, K., Quinn, G. P., Chang, R. J., Finlayson, C., Orwig, K., Valli-Pulaski, H., Moravek, M. B., Zelinski, M. B., Irene Su, H., Vitek, W., Smith, J. F., Jeruss, J. S., Gracia, C., Coutifaris, C., Shah, D., Nahata, L., Gomez-Lobo, V. & 37 others, Appiah, L. C., Brannigan, R. E., Gillis, V., Gradishar, W., Javed, A., Rhoton-Vlasak, A. S., Kondapalli, L. A., Neuber, E., Ginsberg, J. P., Muller, C. H., Hirshfeld-Cytron, J., Kutteh, W. H., Lindheim, S. R., Cherven, B., Meacham, L. R., Rao, P., Torno, L., Sender, L. S., Vadaparampil, S. T., Skiles, J. L., Schafer-Kalkhoff, T., Frias, O. J., Byrne, J., Westphal, L. M., Schust, D. J., Klosky, J. L., McCracken, K. A., Ting, A., Khan, Z., Granberg, C., Lockart, B., Scoccia, B., Laronda, M. M., Mersereau, J. E., Marsh, C., Pavone, M. E. & Woodruff, T. K., Dec 2018, In : Future Oncology. 14, 29, p. 3059-3072 14 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in patients with BRCA1/2 locally recurrent/metastatic breast cancer: Randomized phase II study

Han, H. S., Diéras, V., Robson, M., Palácová, M., Marcom, P. K., Jager, A., Bondarenko, I., Citrin, D., Campone, M., Telli, M. L., Domchek, S. M., Friedlander, M., Kaufman, B., Garber, J. E., Shparyk, Y., Chmielowska, E., Jakobsen, E. H., Kaklamani, V., Gradishar, W., Ratajczak, C. K. & 6 others, Nickner, C., Qin, Q., Qian, J., Shepherd, S. P., Isakoff, S. J. & Puhalla, S., Jan 1 2018, In : Annals of Oncology. 29, 1, p. 154-161 8 p.

Research output: Contribution to journalArticle

58 Scopus citations
2017

A pilot study of cabergoline for the treatment of metastatic breast cancer

Costa, R., Santa-Maria, C. A., Scholtens, D. M., Jain, S., Flaum, L., Gradishar, W. J., Clevenger, C. V. & Kaklamani, V. G., Oct 1 2017, In : Breast Cancer Research and Treatment. 165, 3, p. 585-592 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Breast cancer: Updates and advances in 2016

Giordano, S. B. & Gradishar, W. J., Jan 1 2017, In : Current Opinion in Obstetrics and Gynecology. 29, 1, p. 12-17 6 p.

Research output: Contribution to journalReview article

18 Scopus citations
5 Scopus citations

Clinical variant classification: A comparison of public databases and a commercial testing laboratory

Gradishar, W., Johnson, K., Brown, K., Mundt, E. & Manley, S., Jul 2017, In : Oncologist. 22, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

19 Scopus citations