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Research Output

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2018

SMPL synaptic membranes: Nanodisc-mediated synaptic membrane mimetics expand the toolkit for drug discovery and the molecular cell biology of synapses

Lo Bu, R., Clark, J., DiChiara, T., Sligar, S. G. & Klein, W. L., Jan 1 2018, Neuromethods. Humana Press Inc., p. 227-250 24 p. (Neuromethods; vol. 141).

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Synaptotoxic amyloid-β oligomers: A molecular basis for the cause, diagnosis, and treatment of alzheimer's disease?

Klein, W. L., Feb 15 2013, Alzheimer's Disease: Advances for a New Century. IOS Press, p. 49-65 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Biological targeting and activity of pre-fibrillar Aβ assemblies

Wilcox, K. C., Pitt, J., Sebollela, A., Martirosova, H., Lacor, P. N. & Klein, W. L., Mar 1 2012, Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases. Springer Netherlands, Vol. 9789400727748. p. 103-133 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Synaptotoxic amyloid-β oligomers: A molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease?

Klein, W. L., Dec 1 2012, Alzheimer'S Disease: Advances For A New Century. p. 49-65 17 p. (Advances in Alzheimer's Disease; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingChapter

2008

Soluble Aβ Oligomers in Alzheimer’s Disease

Marcelo, N., De Felice, F. G. & Klein, W. L., 2008, Neurodegenerative Diseases: From Molecular Concepts to Therapeutic Targets. Von Bernhardi, R. & Inestrosa, N. C. (eds.). 1 ed. Nova Science Publishers, p. 9-24 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Why Alzheimer’s is a Disease of Memory: Synaptic Targeting by Pathogenic Aβ Oligomers (ADDLs)

Klein, W. L., De Felice, F. G., Lacor, P. N., Lambert, M. P. & Zhao, W. Q., 2008, Synaptic Plasticity and the Mechanism of Alzheimer's Disease. Selkoe, D. J., Triller, A. & Christen, Y. (eds.). Springer Berlin Heidelberg, p. 103-132 30 p. (Research and Perspectives in Alzheimer's Disease).

Research output: Chapter in Book/Report/Conference proceedingChapter

2007

Molecules that Disrupt Memory Circuits in Alzheimer’s Disease: The Attack on Synapses by Aβ Oligomers (ADDLs)

Klein, W. L., Lacor, P. N., De Felice, F. G. & Ferreira, S. T., 2007, Memories: Molecules and Circuits. Bontempi, B., Silva, A. J. & Christen, Y. (eds.). Springer Berlin Heidelberg, p. 155-179 25 p. (Research and Perspectives in Neurosciences).

Research output: Chapter in Book/Report/Conference proceedingChapter

2006

Cytotoxic Intermediates in the Fibrillation Pathway: Aβ Oligomers in Alzheimer’s Disease as a Case Study

Klein, W. L., 2006, Protein Misfolding, Aggregation, and Conformational Diseases. Uversky, V. N. & Fink, A. L. (eds.). Springer, p. 60-81 22 p. (Protein Reviews; vol. 4).

Research output: Chapter in Book/Report/Conference proceedingChapter

1984

Biochemistry and Regulation of Signal Transduction by Neuronal Acetylcholine Receptors

Klein, W. L., Jan 1 1984, Current Topics in Cellular Regulation. C ed. p. 129-144 16 p. (Current Topics in Cellular Regulation; vol. 24, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations