Grants per year
Personal profile
Research Interests
The primary area of interest of the Lowe lab is maternal metabolism during pregnancy, fetal growth and their interaction. Genetic-, genomics- and metabolomics-based technologies together with a multi-ancestry, population-based cohort of mothers and their offspring from the Hyperglycemia and Adverse Pregnancy Outcome Study are being used to pursue these areas of interest.
Certifications and Licenses
| Internal Medicine | |
| Endocrinology, Diabetes & Metabolism |
Training Experience
| 1981 | Internship, Beth Israel Deaconess Medical Center, Boston |
| 1983 | Residency, Beth Israel Deaconess Medical Center, Boston |
| 1988 | Fellowship, National Institutes of Health |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, University of North Carolina
… → 1980
Research interests keywords
- Diabetes
- Endocrinology
- Genetics
- Genomics
- Maternal/Fetal Nutrition and Metabolism
- Metabolism
Fingerprint
Dive into the research topics where William L Lowe Jr is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The GROWTH Study, Glycemia Range and Offspring Wei
Andrei, A. (PD/PI), Andrei, A. (PD/PI), Andrei, A. (PD/PI) & Lowe Jr, W. L. (Co-Investigator)
Ann & Robert H. Lurie Children's Hospital of Chicago, National Institute of Child Health and Human Development
4/1/23 → 1/31/28
Project: Research project
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Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH)
Allen, N. B. (PD/PI), Lloyd-Jones, D. M. (PD/PI), Lloyd-Jones, D. M. (PD/PI), Allen, N. B. (Co-Investigator), Allen, N. B. (Co-Investigator), Bonner, L. B. (Co-Investigator), Lowe Jr, W. L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Wilkins, J. T. (Co-Investigator), Lowe Jr, W. L. (Other) & Metzger, B. E. (Other)
Ann & Robert H. Lurie Children's Hospital of Chicago, National Heart, Lung, and Blood Institute
3/1/23 → 2/29/28
Project: Research project
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Network Models for Metabolomics
Scholtens, D. M. (PD/PI), Scholtens, D. M. (PD/PI), Scholtens, D. M. (PD/PI), Lowe Jr, W. L. (Co-PD/PI), Lowe Jr, W. L. (Co-PD/PI), Lowe Jr, W. L. (Co-PD/PI), Gill, N. P. (Other), Gill, N. P. (Other) & Gill, N. P. (Other)
University of Massachusetts Amherst, National Library of Medicine
8/1/20 → 7/31/25
Project: Research project
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Glycemic Profiles and Pregnancy Outcomes Study (GLOSS)
Lowe Jr, W. L. (PD/PI), Lowe Jr, W. L. (PD/PI), Yee, L. M. (PD/PI), Yee, L. M. (PD/PI), Aleppo, G. (Co-PD/PI), Szmuilowicz, E. D. (Co-PD/PI), Yee, L. M. (Co-PD/PI), Aleppo, G. (Co-Investigator) & Szmuilowicz, E. D. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
9/20/19 → 7/31/25
Project: Research project
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Predicting Newborn and Childhood Adiposity: An Integrated Omics Approach
Lowe Jr, W. L. (PD/PI), Lowe Jr, W. L. (PD/PI), Scholtens, D. M. (PD/PI), Scholtens, D. M. (PD/PI), Grobman, W. A. (Co-Investigator), Grobman, W. A. (Co-Investigator), Hayes, M. G. (Co-Investigator) & Hayes, M. G. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
8/1/18 → 6/30/25
Project: Research project
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Association Between Breastfeeding and Long-Term Risk of Cardiovascular Disease
Field, C., Grobman, W. A., Wu, J., Palatnik, A., Landon, M. B., Scholtens, D., Lowe Jr, W. L., Shah, N. S., Josefson, J., Khan, S. S. & Venkatesh, K. K., 2025, (Accepted/In press) In: Obstetrics and gynecology. 10.1097/AOG.0000000000005943.Research output: Contribution to journal › Article › peer-review
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Blood Pressure in Pregnancy and Hypertension 10-14 Years after Delivery
Venkatesh, K. K., Grobman, W. A., Wu, J., Costantine, M. M., Landon, M. B., Scholtens, D., Lowe, W., Shah, N. S., Cameron, N. A. & Khan, S. S., Feb 1 2025, In: Obstetrics and gynecology. 145, 2, p. 217-219 3 p.Research output: Contribution to journal › Article › peer-review
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Fetal exposure to gestational diabetes severity and postnatal infant feeding in the first year of life associated with preadolescent obesity: a prospective cohort
Sun, B., Lo, J. C., Greenspan, L. C., King, A. S., Davis, J. N., Faith, M. S., Wakimoto, P., Josefson, J. L., Basi, T., Quesenberry, C. P., Hudson, E. A., Lowe, W., Metzger, B. & Gunderson, E. P., May 2025, In: Obesity. 33, 5, p. 996-1010 15 p.Research output: Contribution to journal › Article › peer-review
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Hypertensive disorders of pregnancy and gestational diabetes mellitus and predicted risk of maternal cardiovascular disease 10–14 years after delivery: A prospective cohort
Venkatesh, K. K., Grobman, W. A., Wu, J., Shah, N. S., Pencina, M., Costantine, M. M., Landon, M. B., Catalano, P., Lowe Jr, W. L., Scholtens, D. M. & Khan, S. S., May 2025, In: Diabetic Medicine. 42, 5, e15516.Research output: Contribution to journal › Article › peer-review
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Impact of hypertensive disorders of pregnancy and gestational diabetes mellitus on offspring cardiovascular health in early adolescence
Venkatesh, K. K., Perak, A. M., Wu, J., Catalano, P., Josefon, J. L., Costantine, M. M., Landon, M. B., Lancki, N., Scholtens, D., Lowe, W., Khan, S. S. & Grobman, W. A., Feb 2025, In: American journal of obstetrics and gynecology. 232, 2, p. 218.e1-218.e12Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Datasets
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Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children’s glucose metabolism—a longitudinal study
Wong, K. K. (Creator), Cheng, F. (Creator), Lim, C. K. P. (Creator), Tam, C. H. T. (Creator), Tutino, G. (Creator), Yuen, L. Y. (Creator), Wang, C. C. (Creator), Hou, Y. (Creator), Chan, M. H. M. (Creator), Ho, C. S. (Creator), Joglekar, M. V. (Creator), Hardikar, A. A. (Creator), Jenkins, A. J. (Creator), Metzger, B. E. (Creator), Lowe, W. L. (Creator), Tam, W. H. (Creator) & Ma, R. C. W. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6584042, https://springernature.figshare.com/collections/Early_emergence_of_sexual_dimorphism_in_offspring_leukocyte_telomere_length_was_associated_with_maternal_and_children_s_glucose_metabolism_a_longitudinal_study/6584042
Dataset
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Additional file 3: Table S5. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d3, https://springernature.figshare.com/articles/dataset/Additional_file_3_Table_S5_of_Transversions_have_larger_regulatory_effects_than_transitions/5027078
Dataset
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Path-level interpretation of Gaussian graphical models using the pair-path subscore
Gill, N. P. (Creator), Balasubramanian, R. (Creator), Bain, J. R. (Creator), Muehlbauer, M. J. (Creator), Lowe, W. L. (Contributor) & Scholtens, D. M. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.5780017, https://springernature.figshare.com/collections/Path-level_interpretation_of_Gaussian_graphical_models_using_the_pair-path_subscore/5780017
Dataset
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Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes
Bodinier, B. (Creator), Tyrrell, J. S. (Creator), Chadeau-Hyam, M. (Creator), Sorensen, T. I. A. (Contributor), Lawlor, D. A. (Creator), Gaillard, R. (Creator), Richmond, R. C. (Creator), Skotte, L. (Creator), Liu, X. (Creator), Håberg, S. E. (Creator), Jaddoe, V. V. W. (Creator), Nohr, E. A. (Creator), Soares, A. L. G. (Creator), McEachan, R. R. C. (Creator), Lowe, W. L. (Creator), Magnus, P. M. (Creator), Magnus, M. C. (Creator), West, J. (Creator), Clayton, G. L. (Creator), Scholtens, D. M. (Creator), Fernández-Sanlés, A. (Creator), Yang, Q. (Creator), Feenstra, B. (Creator), Felix, J. F. (Creator), Hayes, M. G. (Creator), Wright, J. P. (Creator), Kilpi, F. (Creator), Hattersley, A. T. (Creator), Bouchard, L. (Creator), Borges, M. C. (Creator) & Jarvelin, M. R. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.7047258, https://springernature.figshare.com/collections/Integrating_multiple_lines_of_evidence_to_assess_the_effects_of_maternal_BMI_on_pregnancy_and_perinatal_outcomes/7047258
Dataset
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Research data supporting "Associations between a Fetal Imprinted Gene Allele Score and Late Pregnancy Maternal Glucose Concentrations"
Petry, C. J. (Contributor), Mooslehner, K. (Contributor), Prentice, P. (Contributor), Hayes, M. G. (Contributor), Nodzenski, M. (Contributor), Scholtens, D. M. (Contributor), Hughes, I. A. (Contributor), Acerini, C. L. (Contributor), Ong, K. K. (Contributor), Lowe, W. L. (Contributor) & Dunger, D. B. (Contributor), Apollo Cambridge, Mar 28 2017
DOI: 10.17863/cam.8579, https://www.repository.cam.ac.uk/1810/263266
Dataset