Grants per year
Personal profile
Research Interests
The primary area of interest of the Lowe lab is maternal metabolism during pregnancy, fetal growth and their interaction. Genetic-, genomics- and metabolomics-based technologies together with a multi-ancestry, population-based cohort of mothers and their offspring from the Hyperglycemia and Adverse Pregnancy Outcome Study are being used to pursue these areas of interest.
Certifications and Licenses
| Internal Medicine | |
| Endocrinology, Diabetes & Metabolism |
Training Experience
| 1981 | Internship, Beth Israel Deaconess Medical Center, Boston |
| 1983 | Residency, Beth Israel Deaconess Medical Center, Boston |
| 1988 | Fellowship, National Institutes of Health |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, University of North Carolina
… → 1980
Research interests keywords
- Diabetes
- Endocrinology
- Genetics
- Genomics
- Maternal/Fetal Nutrition and Metabolism
- Metabolism
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Hyperglycemia and Adverse Pregnancy Outcome Study-
Lloyd-Jones, D. M. (PD/PI), Allen, N. B. (Co-Investigator), Bonner, L. B. (Co-Investigator), Lowe Jr, W. L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Lowe Jr, W. L. (Other) & Metzger, B. E. (Other)
Ann & Robert H. Lurie Children's Hospital of Chicago, National Heart, Lung, and Blood Institute
3/1/23 → 2/29/28
Project: Research project
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Glycemic Profiles and Pregnancy Outcomes Study (GLOSS)
Lowe Jr, W. L. (PD/PI), Lowe Jr, W. L. (PD/PI), Yee, L. M. (PD/PI), Yee, L. M. (PD/PI), Aleppo, G. (Co-PD/PI), Szmuilowicz, E. D. (Co-PD/PI), Yee, L. M. (Co-PD/PI), Aleppo, G. (Co-Investigator) & Szmuilowicz, E. D. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
9/20/19 → 7/31/25
Project: Research project
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Predicting Newborn and Childhood Adiposity: An Integrated Omics Approach
Lowe Jr, W. L. (PD/PI), Lowe Jr, W. L. (PD/PI), Scholtens, D. M. (PD/PI), Scholtens, D. M. (PD/PI), Grobman, W. A. (Co-Investigator), Grobman, W. A. (Co-Investigator), Hayes, M. G. (Co-Investigator) & Hayes, M. G. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
8/1/18 → 6/30/25
Project: Research project
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Fund to Retain Clinical Scientists at Northwestern University Feinberg School of Medicine
Lowe Jr, W. L. (PD/PI), Lowe Jr, W. L. (PD/PI), Holmes, K. (Co-Investigator), Holmes, K. (Co-Investigator), Sorond, F. A. (Co-Investigator) & Sorond, F. A. (Co-Investigator)
10/15/21 → 10/14/24
Project: Research project
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Network Models for Metabolomics
Scholtens, D. M. (PD/PI), Scholtens, D. M. (PD/PI), Lowe Jr, W. L. (Co-PD/PI), Lowe Jr, W. L. (Co-PD/PI), Gill, N. P. (Other) & Gill, N. P. (Other)
University of Massachusetts Amherst, National Library of Medicine
8/1/20 → 7/31/24
Project: Research project
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Continuous Glucose Monitoring in Pregnancy: New Insights Into Gestational Diabetes With More to Learn
Scifres, C. M. & Lowe, W. L., Aug 2024, In: Diabetes care. 47, 8, p. 1319-1321 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis
ADA/EASD PMDI, Dec 2024, In: Communications Medicine. 4, 1, 75.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Elevated Blood Pressure in Pregnancy and Long-Term Cardiometabolic Health Outcomes
Field, C., Grobman, W. A., Wu, J., Kuang, A., Scholtens, D. M., Lowe, W. L., Shah, N. S., Khan, S. S. & Venkatesh, K. K., Sep 1 2024, In: Obstetrics and gynecology. 144, 3, p. 395-402 8 p.Research output: Contribution to journal › Article › peer-review
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Epidemic-specific association of maternal exposure to per- and polyfluoroalkyl substances (PFAS) and their components with maternal glucose metabolism: A cross-sectional analysis in a birth cohort from Hong Kong
Yang, A., Tam, C. H. T., Wong, K. K., Ozaki, R., Lowe, W. L., Metzger, B. E., Chow, E., Tam, W. H., Wong, C. K. C. & Ma, R. C. W., Mar 20 2024, In: Science of the Total Environment. 917, 170220.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Impact of hypertensive disorders of pregnancy and gestational diabetes mellitus on offspring cardiovascular health in early adolescence
Venkatesh, K. K., Perak, A. M., Wu, J., Catalano, P., Josefon, J. L., Costantine, M. M., Landon, M. B., Lancki, N., Scholtens, D., Lowe, W., Khan, S. S. & Grobman, W. A., 2024, (Accepted/In press) In: American journal of obstetrics and gynecology.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children’s glucose metabolism—a longitudinal study
Wong, K. K. (Creator), Cheng, F. (Creator), Lim, C. K. P. (Creator), Tam, C. H. T. (Creator), Tutino, G. (Creator), Yuen, L. Y. (Creator), Wang, C. C. (Creator), Hou, Y. (Creator), Chan, M. H. M. (Creator), Ho, C. S. (Creator), Joglekar, M. V. (Creator), Hardikar, A. A. (Creator), Jenkins, A. J. (Creator), Metzger, B. E. (Creator), Lowe, W. L. (Creator), Tam, W. H. (Creator) & Ma, R. C. W. (Creator), figshare, 2023
DOI: 10.6084/m9.figshare.c.6584042, https://springernature.figshare.com/collections/Early_emergence_of_sexual_dimorphism_in_offspring_leukocyte_telomere_length_was_associated_with_maternal_and_children_s_glucose_metabolism_a_longitudinal_study/6584042
Dataset
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Research data supporting "Associations between a Fetal Imprinted Gene Allele Score and Late Pregnancy Maternal Glucose Concentrations"
Petry, C. J. (Contributor), Mooslehner, K. (Contributor), Prentice, P. (Contributor), Hayes, M. G. (Contributor), Nodzenski, M. (Contributor), Scholtens, D. M. (Contributor), Hughes, I. A. (Contributor), Acerini, C. L. (Contributor), Ong, K. K. (Contributor), Lowe, W. L. (Contributor) & Dunger, D. B. (Contributor), Apollo Cambridge, Mar 28 2017
DOI: 10.17863/cam.8579, https://www.repository.cam.ac.uk/1810/263266
Dataset
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Data from: Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk
Quilter, C. R. (Creator), Cooper, W. N. (Creator), Cliffe, K. M. (Creator), Skinner, B. M. (Creator), Prentice, P. M. (Creator), Nelson, L. (Creator), Bauer, J. (Creator), Ong, K. K. (Creator), Constância, M. (Contributor), Lowe, W. L. (Creator), Affara, N. A. (Creator) & Dunger, D. B. (Creator), Dryad, Aug 15 2015
DOI: 10.5061/dryad.p6n9s, https://datadryad.org/stash/dataset/doi:10.5061/dryad.p6n9s
Dataset
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Additional file 5: Table S2. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d5, https://springernature.figshare.com/articles/dataset/Additional_file_5_Table_S2_of_Transversions_have_larger_regulatory_effects_than_transitions/5027114
Dataset
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Additional file 7: Table S4. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d7, https://springernature.figshare.com/articles/dataset/Additional_file_7_Table_S4_of_Transversions_have_larger_regulatory_effects_than_transitions/5027144
Dataset