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Research Output

Effects of elevated pCO2 and/or osmolality on the growth and recombinant tPA production of CHO cells

Kimura, R. & Miller, W. M., Oct 5 1996, In : Biotechnology and Bioengineering. 52, 1, p. 152-160 9 p.

Research output: Contribution to journalArticle

68 Scopus citations

Effects of NHE1 expression level on CHO cell responses to environmental stress

Abston, L. R. & Miller, W. M., Mar 1 2005, In : Biotechnology Progress. 21, 2, p. 562-567 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of osmoprotectant compounds on NCAM polysialylation under hyperosmotic stress and elevated pCO2

Schmelzer, A. E. & Miller, W. M., Feb 15 2002, In : Biotechnology and Bioengineering. 77, 4, p. 359-368 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Effects of supported lipid monolayer fluidity on the adhesion of hematopoietic progenitor cell lines to fibronectin-derived peptide ligands for α5β1 and α4β1 integrins

Garcia, A. S., Dellatore, S. M., Messersmith, P. B. & Miller, W. M., Mar 3 2009, In : Langmuir. 25, 5, p. 2994-3002 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effects of synergistic cytokine combinations, low oxygen, and irradiated stroma on the expansion of human cord blood progenitors

Koller, M. R., Bender, J. G., Papoutsakis, E. T. & Miller, W. M., 1992, In : Blood. 80, 2, p. 403-411 9 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations

Elevated pCO2 Inhibits the Polysialylation of the Neural Cell Adhesion Molecule in CHO MT2-1-8 Cell Cultures

Zanghi, J. A., Mendoza, T. P., Knop, R. H. & Miller, W. H., 1998, Proceedings of the 1997 European Society for Animal Cell Technology (ESACT) Meeting. Merten, O. W., Perrin, P. & Griffiths, B. (eds.). Kluwer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas-Permeable Surfaces

Martinez, A. F. & Miller, W. M., Jul 2019, In : Stem Cells Translational Medicine. 8, 7, p. 658-670 13 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Energy, Water and Fish: Biodiversity Impacts of Energy-Sector Water Demand in the United States Depend on Efficiency and Policy Measures

McDonald, R. I., Olden, J. D., Opperman, J. J., Miller, W. M., Fargione, J., Revenga, C., Higgins, J. V. & Powell, J., Nov 21 2012, In : PloS one. 7, 11, e50219.

Research output: Contribution to journalArticle

18 Scopus citations

Energy sprawl or energy efficiency: Climate policy impacts on natural habitat for the United States of America

McDonald, R. I., Fargione, J., Kiesecker, J., Miller, W. M. & Powell, J., Aug 26 2009, In : PloS one. 4, 8, e6802.

Research output: Contribution to journalArticle

201 Scopus citations

Energy sprawl or energy efficiency: Climate policy impacts on natural habitat

McDonald, R. I., Fargione, J., Kiesecker, J., Miller, W. M. & Powell, J., Jan 1 2011, Recent Advances and Issues in Environmental Science. Apple Academic Press, p. 14-29 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Environmental Effects of Cell Physiology and Metabolism: Response to Elevated pCO2

Schmelzer, A. E., deZengotita, V. M. & Miller, W. M., 2002, Proceedings of the 17th European Society for Animal Cell Technology (ESACT) Meeting. Lindner-Olsson, E., Chatzissavidou, N. & Lüllau, E. (eds.). Kluwer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Epithelial cell repopulation and preparation of rodent extracellular matrix scaffolds for renal tissue development

Uzarski, J. S., Su, J., Xie, Y., Zhang, Z. J., Ward, H. H., Wandinger-Ness, A., Miller, W. M. & Wertheim, J. A., Aug 10 2015, In : Journal of Visualized Experiments. 2015, 102, p. 1-9 9 p., e53271.

Research output: Contribution to journalArticle

12 Scopus citations

Erratum: Clinical-scale production of granulocyte progenitor and post-progenitor cells using daniplestim, leridistim, Progenipoietin, Promegapoietin and autologous plasma (Cytotherapy (2000) 2 (85-94))

Patel, S. D., Guo, R., Miller, W. M., Papoutsakis, E. T., Minister, N. I., Baum, C. M. & Winter, J. N., Dec 1 2000, In : Cytotherapy. 2, 5, 1 p.

Research output: Contribution to journalComment/debate

8 Scopus citations

Evaluation of cytokines for expansion of the megakaryocyte and granulocyte lineages

Laiuppa, J. A., Papoutsakis, E. T. & Miller, W. M., Jan 1 1997, In : Stem Cells. 15, 3, p. 198-206 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Expansion of primitive human hematopoietic progenitors in a perfusion bioreactor system with IL-3, IL-6, and stem cell factor

Koller, M. R., Bender, J. G., Miller, W. M. & Papoutsakis, E. T., Mar 1993, In : Bio/Technology. 11, 3, p. 358-363 6 p.

Research output: Contribution to journalArticle

84 Scopus citations

Exploring the role of sirtuin deacetylases in regulating megakaryocyte and erythrocyte differentiation

Duncan, M. T., Yi, M. & Miller, W. M., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 684-685 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ex vivo culture systems for hematopoietic cells

Collins, P. C., Papoutsakis, E. T. & Miller, W. M., Apr 1996, In : Current Opinion in Biotechnology. 7, 2, p. 223-230 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Ex-vivo expansion of CFU-GM and BFU-E in unselected PBMC cultures with Flt3L is enhanced by autologous plasma

Guo, M., Miller, W. M., Papoutsakis, E. T., Patel, S., James, C., Goolsby, C. & Winter, J. N., Jan 1 1999, In : Cytotherapy. 1, 3, p. 183-194 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Ex Vivo Expansion of Hematopoietic Stem and Progenitor Cells

Miller, W. M. & Papoutsakis, E. T., 1993, In : Journal of the Robert H. Lurie Cancer Center of Northwestern University. 3, p. 78-84

Research output: Contribution to journalArticle

115 Scopus citations

Ex vivo expansion of hematopoietic stem and progenitor cells for transplantation.

LaIuppa, J. A., Papoutsakis, E. T. & Miller, W. M., 1997, In : Cancer treatment and research. 77, p. 159-186 28 p.

Research output: Contribution to journalReview article

5 Scopus citations

Ex vivo expansion of primitive hematopoietic cells for cellular therapies: An overview

McAdams, T. A., Sandstrom, C. E., Miller, W. M., Bender, J. G. & Papoutsakis, E. T., Jan 1 1995, In : Cytotechnology. 18, 1-2, p. 133-146 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Factors affecting megakaryocytic expansion in hematopoietic cultures for transplant therapies

LaIauppa, J. A., Miller, W. M. & Papoutsakis, E. T., 1997, Proceedings of the 1996 European Society for Animal Cell Technology (ESACT) Meeting. Corrondo, J. T., Griffiths, B. & Moreira, J. L. P. (eds.). Kluwer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

First-order toxicity assays for eye irritation using cell lines: Parameters that affect in Vitro evaluation

Pasternak, A. S. & Miller, W. M., May 1 1995, In : Toxicological Sciences. 25, 2, p. 253-263 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

First-Order Toxicity Assays for Eye Irritation Using Cell Lines: Parameters That Affect in Vitro Evaluation

Pasternak, A. S. & Miller, W. M., May 1 1995, In : Fundamental and Applied Toxicology. 25, 2, p. 253-263 11 p.

Research output: Contribution to journalArticle

Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes

Huang, L. T., Paredes, C. J., Papoutsakis, E. T. & Miller, W. M., Sep 19 2007, In : Physiological genomics. 31, 1, p. 114-125 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis

Fuhrken, P. G., Chen, C., Apostolidis, P. A., Wang, M., Miller, W. M. & Papoutsakis, E. T., Apr 22 2008, In : Physiological genomics. 33, 2, p. 159-169 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Glycosylation of CHO-derived recombinant tPA produced under elevated pCO2

Kimura, R. & Miller, W. M., May 1 1997, In : Biotechnology Progress. 13, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

51 Scopus citations
1 Scopus citations

Hematopoietic cell culture therapies (Part I): Cell culture considerations

McAdams, T. A., Miller, W. M. & Papoutsakis, E. T., Sep 1996, In : Trends in biotechnology. 14, 9, p. 341-349 9 p.

Research output: Contribution to journalReview article

41 Scopus citations

Hematopoietic cell culture therapies (Part II): Clinical aspects and applications

McAdams, T. A., Winter, J. N., Miller, W. M. & Papoutsakis, E. T., Oct 1996, In : Trends in biotechnology. 14, 10, p. 388-396 9 p.

Research output: Contribution to journalReview article

33 Scopus citations

Hematopoietic Cells for Cellular and Gene Therapy: I. Basic Assay Techniques

Miller, W. M., 1999, Animal Cell Biotechnology: Methods and Protocols (Methods in Molecular Biology Series). Totowa, NJ: Humana Press, p. 211-227

Research output: Chapter in Book/Report/Conference proceedingChapter

Hematopoietic Cells for Cellular and Gene Therapy: II. Expansion Protocols

Miller, W. M., 1999, Animal Cell Biotechnology: Methods and Protocols (Methods in Molecular Biology Series). Totowa, NJ: Humana Press, p. 229-238

Research output: Chapter in Book/Report/Conference proceedingChapter

Higher pH promotes megakaryocytic maturation and apoptosis

Yang, H., Miller, W. M. & Papoutsakis, E. T., Jan 1 2002, In : Stem Cells. 20, 4, p. 320-328 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Hoxa10 null animals exhibit reduced platelet biogenesis

Konieczna, I. M., Deluca, T. A., Eklund, E. A. & Miller, W. M., Apr 1 2016, In : British Journal of Haematology. 173, 2, p. 303-313 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
12 Scopus citations

Hybridoma antibody content and production rate in continuous culture: Effect of dilution rate

Reddy, S. & Miller, W. M., Nov 1 1992, In : Biotechnology Letters. 14, 11, p. 1007-1012 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hyperosmotic stress and elevated pCO2 alter monoclonal antibody charge distribution and monosaccharide content

Schmelzer, A. E. & Miller, W. M., Apr 22 2002, In : Biotechnology Progress. 18, 2, p. 346-353 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Hypoxia, Effects on Animal Cells

Miller, W. M., 1999, Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation. New York: wiley, p. 1418-1433

Research output: Chapter in Book/Report/Conference proceedingChapter

Initiation, Maintenance, and Quantification of Human Hematopoietic Cell Cultures

Collins, P. C., Patel, S. D. & Miller, W. M., 1999, Methods in Molecular Medicine. Morgan, J. R. & Yarmush, M. L. (eds.). Totowa, NJ: Humana Press, Vol. 18: Tissue Engineeri. p. 271-292

Research output: Chapter in Book/Report/Conference proceedingChapter

Inverse-signal analysis with PCA

Reddy, V. N., Miller, W. M. & Mavrovouniotis, M. L., Feb 1 1997, In : Chemometrics and Intelligent Laboratory Systems. 36, 1, p. 17-30 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
18 Scopus citations

Knowledge, attitudes, intentions, and behavior related to green infrastructure for flood management: A systematic literature review

Venkataramanan, V., Lopez, D., McCuskey, D. J., Kiefus, D., McDonald, R. I., Miller, W. M., Packman, A. I. & Young, S. L., Jun 10 2020, In : Science of the Total Environment. 720, 137606.

Research output: Contribution to journalReview article

2 Scopus citations

Leveraging large-scale transcriptional analysis in cell culture engineering

Fuhrken, P. G., Miller, W. M. & Papoutsakis, E. T., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lineage plasticity and determinism in ex vivo differentiation of hematopoietic stem cells examined by large-scale transcriptional analysis

Huang, L. T., Chen, C., Papoutsakis, E. T. & Miller, W. M., Dec 1 2004. 1 p.

Research output: Contribution to conferencePaper

Lineage switching of hematopoietic cells in response to changes in culture conditions

Huang, L. T., Chen, C., Papoutsakis, E. T. & Miller, W. M., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lipopeptide ligands presented in a hybrid bilayer membrane activate cell signaling and support hematopoietic cell growth

King, J. A., Dellatore, S. M., Jensen, T. W., Hu, B. H., Messersmith, P. B. & Miller, W. M., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lipopeptides incorporated into supported phospholipid monolayers have high specific activity at low incorporation levels

Jensen, T. W., Hu, B. H., Delatore, S. M., Garcia, A. S., Messersmith, P. B. & Miller, W. M., Nov 24 2004, In : Journal of the American Chemical Society. 126, 46, p. 15223-15230 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Loss of fatty acid Δ6 desaturating ability in human mammary epithelial cells that express an activated c-Ha-ras oncogene

Grammatikos, S. I., Harvey, M. J., Subbaiah, P. V., Victor, T. A. & Miller, W. M., Jan 1 1995, In : International Journal of Oncology. 6, 5, p. 1039-1046 8 p.

Research output: Contribution to journalArticle

9 Scopus citations