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Research Output

Article

Ex vivo expansion of primitive hematopoietic cells for cellular therapies: An overview

McAdams, T. A., Sandstrom, C. E., Miller, W. M., Bender, J. G. & Papoutsakis, E. T., Jan 1 1995, In : Cytotechnology. 18, 1-2, p. 133-146 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

First-order toxicity assays for eye irritation using cell lines: Parameters that affect in Vitro evaluation

Pasternak, A. S. & Miller, W. M., May 1 1995, In : Toxicological Sciences. 25, 2, p. 253-263 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

First-Order Toxicity Assays for Eye Irritation Using Cell Lines: Parameters That Affect in Vitro Evaluation

Pasternak, A. S. & Miller, W. M., May 1 1995, In : Fundamental and Applied Toxicology. 25, 2, p. 253-263 11 p.

Research output: Contribution to journalArticle

Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes

Huang, L. T., Paredes, C. J., Papoutsakis, E. T. & Miller, W. M., Sep 19 2007, In : Physiological genomics. 31, 1, p. 114-125 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis

Fuhrken, P. G., Chen, C., Apostolidis, P. A., Wang, M., Miller, W. M. & Papoutsakis, E. T., Apr 22 2008, In : Physiological genomics. 33, 2, p. 159-169 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Glycosylation of CHO-derived recombinant tPA produced under elevated pCO2

Kimura, R. & Miller, W. M., May 1 1997, In : Biotechnology Progress. 13, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Higher pH promotes megakaryocytic maturation and apoptosis

Yang, H., Miller, W. M. & Papoutsakis, E. T., Jan 1 2002, In : Stem Cells. 20, 4, p. 320-328 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Hoxa10 null animals exhibit reduced platelet biogenesis

Konieczna, I. M., Deluca, T. A., Eklund, E. A. & Miller, W. M., Apr 1 2016, In : British Journal of Haematology. 173, 2, p. 303-313 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
12 Scopus citations

Hybridoma antibody content and production rate in continuous culture: Effect of dilution rate

Reddy, S. & Miller, W. M., Nov 1 1992, In : Biotechnology Letters. 14, 11, p. 1007-1012 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hyperosmotic stress and elevated pCO2 alter monoclonal antibody charge distribution and monosaccharide content

Schmelzer, A. E. & Miller, W. M., Apr 22 2002, In : Biotechnology Progress. 18, 2, p. 346-353 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Inverse-signal analysis with PCA

Reddy, V. N., Miller, W. M. & Mavrovouniotis, M. L., Feb 1 1997, In : Chemometrics and Intelligent Laboratory Systems. 36, 1, p. 17-30 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
18 Scopus citations

Lipopeptides incorporated into supported phospholipid monolayers have high specific activity at low incorporation levels

Jensen, T. W., Hu, B. H., Delatore, S. M., Garcia, A. S., Messersmith, P. B. & Miller, W. M., Nov 24 2004, In : Journal of the American Chemical Society. 126, 46, p. 15223-15230 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Loss of fatty acid Δ6 desaturating ability in human mammary epithelial cells that express an activated c-Ha-ras oncogene

Grammatikos, S. I., Harvey, M. J., Subbaiah, P. V., Victor, T. A. & Miller, W. M., Jan 1 1995, In : International Journal of Oncology. 6, 5, p. 1039-1046 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
25 Scopus citations

Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition

Giammona, L. M., Panuganti, S., Kemper, J. M., Apostolidis, P. A., Lindsey, S., Papoutsakis, E. T. & Miller, W. M., Nov 2009, In : Experimental Hematology. 37, 11, p. 1340-1352.e3

Research output: Contribution to journalArticle

31 Scopus citations

Megakaryocyte polyploidization and proplatelet formation in low-attachment conditions

Schlinker, A. C., Duncan, M. T., DeLuca, T. A., Whitehead, D. C. & Miller, W. M., Jul 15 2016, In : Biochemical Engineering Journal. 111, p. 24-33 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Model-based estimation of myeloid hematopoietic progenitor cells in ex vivo cultures for cell and gene therapies

Yang, H., Papoutsakis, E. T. & Miller, W. M., Jan 7 2001, In : Biotechnology and Bioengineering. 72, 2, p. 144-155 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Modeling ex vivo hematopoiesis using chemical engineering metaphors

Nielsen, L. K., Papoutsakis, E. T. & Miller, W. M., May 15 1998, In : Chemical Engineering Science. 53, 10, p. 1913-1925 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Modeling pO2 distributions in the bone marrow hematopoietic compartment. I. Krogh's model

Chow, D. C., Wenning, L. A., Miller, W. M. & Papoutsakis, E. T., Jan 1 2001, In : Biophysical Journal. 81, 2, p. 675-684 10 p.

Research output: Contribution to journalArticle

185 Scopus citations

Modeling pO2 distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models

Chow, D. C., Wenning, L. A., Miller, W. M. & Papoutsakis, E. T., Jan 1 2001, In : Biophysical Journal. 81, 2, p. 685-696 12 p.

Research output: Contribution to journalArticle

223 Scopus citations
13 Scopus citations

Mussel-inspired surface chemistry for multifunctional coatings

Lee, H., Dellatore, S. M., Miller, W. M. & Messersmith, P. B., Oct 19 2007, In : Science. 318, 5849, p. 426-430 5 p.

Research output: Contribution to journalArticle

5745 Scopus citations

n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines

Grammatikos, S. I., Subbaiah, P. V., Victor, T. A. & Miller, W. M., Aug 1994, In : British Journal of Cancer. 70, 2, p. 219-227 9 p.

Research output: Contribution to journalArticle

127 Scopus citations

Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes

Giammona, L. M., Fuhrken, P. G., Papoutsakis, E. T. & Miller, W. M., Nov 1 2006, In : British Journal of Haematology. 135, 4, p. 554-566 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Nuclei-size distributions as predictive tools of hematopoietic cell proliferation

Collins, P. C., Patel, S. D., Papoutsakis, E. T. & Miller, W. M., Jan 1 1999, In : Cytotherapy. 1, 2, p. 99-110 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Optimization and critical evaluation of decellularization strategies to develop renal extracellular matrix scaffolds as biological templates for organ engineering and transplantation

Caralt, M., Uzarski, J. S., Iacob, S., Obergfell, K. P., Berg, N., Bijonowski, B. M., Kiefer, K. M., Ward, H. H., Wandinger-Ness, A., Miller, W. M., Zhang, Z. J., Abecassis, M. M. & Wertheim, J. A., Jan 1 2015, In : American Journal of Transplantation. 15, 1, p. 64-75 12 p.

Research output: Contribution to journalArticle

108 Scopus citations

Oxygen tension alters the effects of cytokines on the megakaryocyte, erythrocyte, and granulocyte lineages

Laluppa, J. A., Papoutsakis, E. T. & Miller, W. M., Aug 8 1998, In : Experimental Hematology. 26, 9, p. 835-843 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes

Mostafa, S. S., Miller, W. M. & Terry Papoutsakis, E., Dec 1 2000, In : British Journal of Haematology. 111, 3, p. 879-889 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes

Mostafa, S. S., Papoutsakis, E. T. & Miller, W. M., Jul 12 2001, In : Experimental Hematology. 29, 7, p. 873-883 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

pH is a potent modulator of erythroid differentiation

Mcadams, T. A., Miller, W. M. & Papoutsakis, E. T., Nov 26 1998, In : British Journal of Haematology. 103, 2, p. 317-325 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Phosphate feeding improves high-cell-concentration NSO myeloma culture performance for monoclonal antibody production

Dezengotita, V. M., Miller, W. M., Aunins, J. G. & Zhou, W., Sep 5 2000, In : Biotechnology and Bioengineering. 69, 5, p. 566-576 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Physiologically significant effects of pH and oxygen tension on granulopoiesis

Hevehan, D. L., Papoutsakis, E. T. & Miller, W. M., Mar 1 2000, In : Experimental Hematology. 28, 3, p. 267-275 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

Polymer biocompatibility-effect on hybridoma growth and metabolism

Miller, W. M., Lin, A. A., Wilke, C. R. & Blanch, H. W., Jul 1 1986, In : Biotechnology Letters. 8, 7, p. 463-468 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Population balance model of in vivo neutrophil formation following bone marrow rescue therapy

Nielsen, L. K., Bender, J. G., Miller, W. M. & Papoutsakis, E. T., 1998, In : Cytotechnology. 28, 1-3, p. 157-162 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Production of tPA in recombinant CHO cells under oxygen‐limited conditions

Lin, A. A., Kimura, R. & Miller, W. M., Jul 1993, In : Biotechnology and Bioengineering. 42, 3, p. 339-350 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Proposed megakaryocytic regulon of p53: The genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation

Apostolidis, P. A., Lindsey, S., Miller, W. M. & Papoutsakis, E. T., Jun 1 2012, In : Physiological genomics. 44, 12, p. 638-650 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles

Pascoe, D. E., Arnott, D., Papoutsakis, E. T., Miller, W. M. & Andersen, D. C., Oct 1 2007, In : Biotechnology and Bioengineering. 98, 2, p. 391-410 20 p.

Research output: Contribution to journalArticle

55 Scopus citations

Real-time method for determining the colony-forming cell content of human hematopoietic cell cultures

Collins, P. C., Nielsen, L. K., Wong, C. K., Papoutsakis, E. T. & Miller, W. M., Aug 20 1997, In : Biotechnology and Bioengineering. 55, 4, p. 693-700 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Reduced oxygen tension increases hematopoiesis in long-term culture of human stem and progenitor cells from cord blood and bone marrow

Koller, M. R., Bender, J. G., Miller, W. M. & Papoutsakis, E. T., Jan 1 1992, In : Experimental Hematology. 20, 2, p. 264-270 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Role of nucleotide sugar pools in the inhibition of NCAM polysialylation by ammonia

Zanghi, J. A., Mendoza, T. P., Schmelzer, A. E., Knop, R. H. & Miller, W. M., Nov 1 1998, In : Biotechnology Progress. 14, 6, p. 834-844 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Role of tumor suppressor p53 in megakaryopoiesis and platelet function

Apostolidis, P. A., Woulfe, D. S., Chavez, M., Miller, W. M. & Papoutsakis, E. T., Feb 2012, In : Experimental Hematology. 40, 2, p. 131-142.e4

Research output: Contribution to journalArticle

22 Scopus citations

Selected amino acids protect hybridoma and CHO cells from elevated carbon dioxide and osmolality

DeZengotita, V. M., Abston, L. R., Schmelzer, A. E., Shaw, S. & Miller, W. M., Jun 30 2002, In : Biotechnology and Bioengineering. 78, 7, p. 741-752 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration

Schlinker, A. C., Radwanski, K., Wegener, C., Min, K. & Miller, W. M., Apr 1 2015, In : Biotechnology and Bioengineering. 112, 4, p. 788-800 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation

Duncan, M. T., DeLuca, T. A., Kuo, H. Y., Yi, M., Mrksich, M. & Miller, W. M., May 15 2016, In : Experimental Cell Research. 344, 1, p. 40-52 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Small increases in pH enhance retroviral vector transduction efficiency of NIH-3T3 cells

Jensen, T. W., Chen, Y. & Miller, W. M., Jan 1 2003, In : Biotechnology Progress. 19, 1, p. 216-223 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Soil hydrology drives ecological niche differentiation in a native prairie microbiome

Griffin, J. S., Haug, L. A., Rivera, V. A., Hernandez Gonzalez, L. M., Kelly, J. J., Miller, W. M., Wells, G. F. & Packman, A. I., Feb 1 2020, In : FEMS microbiology ecology. 96, 1, fiz163.

Research output: Contribution to journalArticle

1 Scopus citations

Stirred culture of peripheral and cord blood hematopoietic cells offers advantages over traditional static systems for clinically relevant applications

Collins, P. C., Miller, W. M. & Papoutsakis, E. T., Sep 5 1998, In : Biotechnology and Bioengineering. 59, 5, p. 534-543 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

Surface presentation of bioactive ligands in a nonadhesive background using DOPA-tethered biotinylated poly(ethylene glycol)

Gunawan, R. C., King, J. A., Lee, B. P., Messersmith, P. B. & Miller, W. M., Oct 9 2007, In : Langmuir. 23, 21, p. 10635-10643 9 p.

Research output: Contribution to journalArticle

36 Scopus citations