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Research Output

Article

Synergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA

Ojima, Y., Duncan, M. T., Nurhayati, R. W., Taya, M. & Miller, W. M., Aug 15 2013, In : Experimental Cell Research. 319, 14, p. 2205-2215 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
46 Scopus citations

The transient responses of hybridoma cells to nutrient additions in continuous culture: II. Glutamine pulse and step changes

Miller, W. M., Wilke, C. R. & Blanch, H. W., Jan 1 1989, In : Biotechnology and Bioengineering. 33, 4, p. 487-499 13 p.

Research output: Contribution to journalArticle

75 Scopus citations

Three-stage Ex vivo expansion of high-ploidy megakaryocytic cells: Toward large-scale platelet production

Panuganti, S., Schlinker, A. C., Lindholm, P. F., Papoutsakis, E. T. & Miller, W. M., Apr 1 2013, In : Tissue Engineering - Part A. 19, 7-8, p. 998-1014 17 p.

Research output: Contribution to journalArticle

38 Scopus citations

Transduction efficiency of pantropic retroviral vectors is controlled by the envelope plasmid to vector plasmid ratio

Chen, Y., Miller, W. M. & Aiyar, A., Jan 1 2005, In : Biotechnology Progress. 21, 1, p. 274-282 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Trans-epithelial electrical resistance in bronchial epithelial cells: effects of continuous H2O2 exposure and KGF

Chapman, K., Miller, W. M. & Waters, C., Dec 1 2000, In : Annals of Biomedical Engineering. 28, SUPPL. 1

Research output: Contribution to journalArticle

Transient responses of hybridoma cells to lactate and ammonia pulse and step changes in continuous culture

Miller, W. M., Wilke, C. R. & Blanch, H. W., Sep 1 1988, In : Bioprocess Engineering. 3, 3, p. 113-122 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

Transient responses of hybridoma cells to nutrient additions in continuous culture: I. Glucose pulse and step changes

Miller, W. M., Wilke, C. R. & Blanch, H. W., Jan 20 1989, In : Biotechnology and Bioengineering. 33, 4, p. 477-486 10 p.

Research output: Contribution to journalArticle

98 Scopus citations

Transient responses of hybridoma metabolism to changes in the oxygen supply rate in continuous culture

Miller, W. M., Wilke, C. R. & Blanch, H. W., Sep 1 1988, In : Bioprocess Engineering. 3, 3, p. 103-111 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Transport in a grooved perfusion flat-bed bioreactor for cell therapy applications

Horner, M., Miller, W. M., Ottino, J. M. & Papoutsakis, E. T., Sep 1 1998, In : Biotechnology Progress. 14, 5, p. 689-698 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis

Fuhrken, P. G., Apostolidis, P. A., Lindsey, S., Miller, W. M. & Papoutsakis, E. T., Jun 6 2008, In : Journal of Biological Chemistry. 283, 23, p. 15589-15600 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

UDP-AT-Acetylhexosamine Modulation by Glucosamine and Uridine in NCI N-417 Variant Small Cell Lung Cancer Cells: 31P Nuclear Magnetic Resonance Results

Pederson, N. V., Knop, R. H. & Miller, W. M., Jul 1992, In : Cancer Research. 52, 13, p. 3782-3786 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Variations in culture pH affect the cloning efficiency and differentiation of progenitor cells in ex vivo haemopoiesis

Mcadams, T. A., Miller, W. M. & Papoutsakis, E. T., Jan 1 1997, In : British Journal of Haematology. 97, 4, p. 889-895 7 p.

Research output: Contribution to journalArticle

45 Scopus citations
Chapter

Energy sprawl or energy efficiency: Climate policy impacts on natural habitat

McDonald, R. I., Fargione, J., Kiesecker, J., Miller, W. M. & Powell, J., Jan 1 2011, Recent Advances and Issues in Environmental Science. Apple Academic Press, p. 14-29 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hematopoietic Cells for Cellular and Gene Therapy: I. Basic Assay Techniques

Miller, W. M., 1999, Animal Cell Biotechnology: Methods and Protocols (Methods in Molecular Biology Series). Totowa, NJ: Humana Press, p. 211-227

Research output: Chapter in Book/Report/Conference proceedingChapter

Hematopoietic Cells for Cellular and Gene Therapy: II. Expansion Protocols

Miller, W. M., 1999, Animal Cell Biotechnology: Methods and Protocols (Methods in Molecular Biology Series). Totowa, NJ: Humana Press, p. 229-238

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypoxia, Effects on Animal Cells

Miller, W. M., 1999, Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation. New York: wiley, p. 1418-1433

Research output: Chapter in Book/Report/Conference proceedingChapter

Initiation, Maintenance, and Quantification of Human Hematopoietic Cell Cultures

Collins, P. C., Patel, S. D. & Miller, W. M., 1999, Methods in Molecular Medicine. Morgan, J. R. & Yarmush, M. L. (eds.). Totowa, NJ: Humana Press, Vol. 18: Tissue Engineeri. p. 271-292

Research output: Chapter in Book/Report/Conference proceedingChapter

Quantitative Analysis of Cell Growth, Metabolism, and Product Formation

Miller, W. M., 1993, Cell & Tissue Culture: Laboratory Procedures. Chichester, England: John Wiley & Sons, Ltd., p. 8B1.1-26

Research output: Chapter in Book/Report/Conference proceedingChapter

Quantitative Analysis of Cell Growth, Metabolism, and Product Formation

Miller, W. M. & Reddy, S., 1998, Cell & Tissue Culture: Laboratory Procedures in Biotechnology. Doyle, A. & Griffiths, J. B. (eds.). Chichester, England: John Wiley & Sons, Ltd.

Research output: Chapter in Book/Report/Conference proceedingChapter

Erratum: Clinical-scale production of granulocyte progenitor and post-progenitor cells using daniplestim, leridistim, Progenipoietin, Promegapoietin and autologous plasma (Cytotherapy (2000) 2 (85-94))

Patel, S. D., Guo, R., Miller, W. M., Papoutsakis, E. T., Minister, N. I., Baum, C. M. & Winter, J. N., Dec 1 2000, In : Cytotherapy. 2, 5, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
Conference article

A systems biology approach to hematopoietic stem-cell differentiation

Papoutsakis, E. T., Huang, L. T., Yang, H. & Miller, W. M., Jan 1 2002, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1, 1 p.

Research output: Contribution to journalConference article

Conference contribution

Apoptotic signaling pathways in megakaryocytes

Giammona, L. M., Papoutsakis, E. T. & Miller, W. M., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Elevated pCO2 Inhibits the Polysialylation of the Neural Cell Adhesion Molecule in CHO MT2-1-8 Cell Cultures

Zanghi, J. A., Mendoza, T. P., Knop, R. H. & Miller, W. H., 1998, Proceedings of the 1997 European Society for Animal Cell Technology (ESACT) Meeting. Merten, O. W., Perrin, P. & Griffiths, B. (eds.). Kluwer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Environmental Effects of Cell Physiology and Metabolism: Response to Elevated pCO2

Schmelzer, A. E., deZengotita, V. M. & Miller, W. M., 2002, Proceedings of the 17th European Society for Animal Cell Technology (ESACT) Meeting. Lindner-Olsson, E., Chatzissavidou, N. & Lüllau, E. (eds.). Kluwer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Exploring the role of sirtuin deacetylases in regulating megakaryocyte and erythrocyte differentiation

Duncan, M. T., Yi, M. & Miller, W. M., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 684-685 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Factors affecting megakaryocytic expansion in hematopoietic cultures for transplant therapies

LaIauppa, J. A., Miller, W. M. & Papoutsakis, E. T., 1997, Proceedings of the 1996 European Society for Animal Cell Technology (ESACT) Meeting. Corrondo, J. T., Griffiths, B. & Moreira, J. L. P. (eds.). Kluwer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Leveraging large-scale transcriptional analysis in cell culture engineering

Fuhrken, P. G., Miller, W. M. & Papoutsakis, E. T., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lineage switching of hematopoietic cells in response to changes in culture conditions

Huang, L. T., Chen, C., Papoutsakis, E. T. & Miller, W. M., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lipopeptide ligands presented in a hybrid bilayer membrane activate cell signaling and support hematopoietic cell growth

King, J. A., Dellatore, S. M., Jensen, T. W., Hu, B. H., Messersmith, P. B. & Miller, W. M., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Megakaryocyte development illuminated by transcriptional analysis

Fuhrken, P. G., Chen, C., Miller, W. M. & Papoutsakis, E. T., Dec 1 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mussel-inspired biofunctional coatings that can be applied to any material surface

Lee, H., Dellatore, S. M., Miller, W. M. & Messersmith, P. B., Dec 1 2008, 8th World Biomaterials Congress 2008. 1 p. (8th World Biomaterials Congress 2008; vol. 4).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nicotinamide increases the megakaryocytic maturation of human hematopoietic stem cells primarily due to sirtuin inhibition

Panuganti, S., Papoutsakis, E. T. & Miller, W. M., Dec 1 2008, AIChE100 - 2008 AIChE Annual Meeting, Conference Proceedings. (AIChE Annual Meeting, Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Role of lysine deacetylases in megakaryocyte differentiation

DeLuca, T., Kuo, H. Y., Konieczna, I., Mrksich, M. & Miller, W. M., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 188-189 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Transcription factor activity profiling reveals new insights into megakaryocyte and erythrocyte differentiation

Duncan, M. T., Shin, S., Mays, Z., Shea, L. D. & Miller, W. M., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 196-197 2 p. (Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biotechnology progress: Editorial

Miller, W. M. & Schoenfeld, R. A., Jan 1 2000, In : Biotechnology Progress. 16, 5, 1 p.

Research output: Contribution to journalEditorial

Editorial

Miller, W. M., Apr 15 2009, In : Biochemical Engineering Journal. 44, 1, 1 p.

Research output: Contribution to journalEditorial

Editorial

Miller, W. M., Aug 15 2009, In : Biochemical Engineering Journal. 45, 3, 1 p.

Research output: Contribution to journalEditorial

Letter

Discrimination of fluorinated uridine metabolites in N‐417 small cell lung cancer cell extracts via 19F‐ and 31P‐NMR

Pederson, N. V., Zanghi, J. A., Miller, W. M. & Knop, R. H., Jan 1 1994, In : Magnetic resonance in medicine. 31, 2, p. 224-228 5 p.

Research output: Contribution to journalLetter

7 Scopus citations
Paper

DNA-array based transcriptional analysis elucidates granulocytic differentiation of human stem cells

Huang, L. T., Miller, W. M. & Papoutsakis, E. T., Dec 1 2004. 1 p.

Research output: Contribution to conferencePaper

Lineage plasticity and determinism in ex vivo differentiation of hematopoietic stem cells examined by large-scale transcriptional analysis

Huang, L. T., Chen, C., Papoutsakis, E. T. & Miller, W. M., Dec 1 2004. 1 p.

Research output: Contribution to conferencePaper

Maturation and death in terminal megakaryocytic differentiation: Phenotypic and DNA-microarray characterization

Fuhrken, P. G., Chen, C., Giammona, L. M., Miller, W. M. & Papoutsakis, E. T., Dec 1 2004. 1 p.

Research output: Contribution to conferencePaper

Review article

A systematic review of the human health and social well-being outcomes of green infrastructure for stormwater and flood management

Venkataramanan, V., Packman, A. I., Peters, D. R., Lopez, D., McCuskey, D. J., McDonald, R. I., Miller, W. M. & Young, S. L., Sep 15 2019, In : Journal of Environmental Management. 246, p. 868-880 13 p.

Research output: Contribution to journalReview article

12 Scopus citations

Bioreactor design for perfusion-based, highly vascularized organ regeneration

Bijonowski, B. M., Miller, W. M. & Wertheim, J. A., Feb 2013, In : Current Opinion in Chemical Engineering. 2, 1, p. 32-40 9 p.

Research output: Contribution to journalReview article

22 Scopus citations

Bioreactor development for stem cell expansion and controlled differentiation

King, J. A. & Miller, W. M., Aug 1 2007, In : Current Opinion in Chemical Biology. 11, 4, p. 394-398 5 p.

Research output: Contribution to journalReview article

167 Scopus citations

Comparison of whole serum-deprived media for ex vivo expansion of hematopoietic progenitor cells from cord blood and mobilized peripheral blood mononuclear cells

Sandstrom, C. E., Collins, P. C., Mcadams, T. A., Bender, J. G., Papoutsakis, E. T. & Miller, W. M., Oct 1996, In : Journal of Hematotherapy and Stem Cell Research. 5, 5, p. 461-473 13 p.

Research output: Contribution to journalReview article

16 Scopus citations