William M Miller

2020

Soil hydrology drives ecological niche differentiation in a native prairie microbiome

Griffin, J. S., Haug, L. A., Rivera, V. A., Hernandez Gonzalez, L. M., Kelly, J. J., Miller, W. M., Wells, G. F. & Packman, A. I., Feb 1 2020, In : FEMS microbiology ecology. 96, 1, fiz163.

Research output: Contribution to journal › Article

1 Scopus citations

2019

Characterization of soil profiles and elemental concentrations reveals deposition of heavy metals and phosphorus in a Chicago-area nature preserve, Gensburg Markham Prairie

Hernandez Gonzalez, L. M., Rivera, V. A., Phillips, C. B., Haug, L. A., Hatch, S. L., Yeager, L. E., Chang, H., Alvarez, J., Gnaedinger, K. J., Miller, W. M. & Packman, A. I., Nov 1 2019, In : Journal of Soils and Sediments. 19, 11, p. 3817-3831 15 p.

Research output: Contribution to journal › Article

2 Scopus citations

Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34⁺ Cells Using Gas-Permeable Surfaces

Martinez, A. F. & Miller, W. M., Jul 2019, In : Stem Cells Translational Medicine. 8, 7, p. 658-670 13 p.

Research output: Contribution to journal › Article

Open Access

2 Scopus citations

2017

A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets

Martinez, A. F., McMahon, R. D., Horner, M. & Miller, W. M., Nov 1 2017, In : Biotechnology Progress. 33, 6, p. 1614-1629 16 p.

Research output: Contribution to journal › Article

5 Scopus citations

Essential design considerations for the resazurin reduction assay to noninvasively quantify cell expansion within perfused extracellular matrix scaffolds

Uzarski, J. S., DiVito, M. D., Wertheim, J. A. & Miller, W. M., Jun 1 2017, In : Biomaterials. 129, p. 163-175 13 p.

Research output: Contribution to journal › Article

8 Scopus citations

2016

Hoxa10 null animals exhibit reduced platelet biogenesis

Konieczna, I. M., Deluca, T. A., Eklund, E. A. & Miller, W. M., Apr 1 2016, In : British Journal of Haematology. 173, 2, p. 303-313 11 p.

Research output: Contribution to journal › Article

2 Scopus citations

Megakaryocyte polyploidization and proplatelet formation in low-attachment conditions

Schlinker, A. C., Duncan, M. T., DeLuca, T. A., Whitehead, D. C. & Miller, W. M., Jul 15 2016, In : Biochemical Engineering Journal. 111, p. 24-33 10 p.

Research output: Contribution to journal › Article

3 Scopus citations

SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation

Duncan, M. T., DeLuca, T. A., Kuo, H. Y., Yi, M., Mrksich, M. & Miller, W. M., May 15 2016, In : Experimental Cell Research. 344, 1, p. 40-52 13 p.

Research output: Contribution to journal › Article

4 Scopus citations

2015

Dual-Purpose Bioreactors to Monitor Noninvasive Physical and Biochemical Markers of Kidney and Liver Scaffold Recellularization

Uzarski, J. S., Bijonowski, B. M., Wang, B., Ward, H. H., Wandinger-Ness, A., Miller, W. M. & Wertheim, J. A., Oct 1 2015, In : Tissue Engineering - Part C: Methods. 21, 10, p. 1032-1043 12 p.

Research output: Contribution to journal › Article

26 Scopus citations

Epithelial cell repopulation and preparation of rodent extracellular matrix scaffolds for renal tissue development

Uzarski, J. S., Su, J., Xie, Y., Zhang, Z. J., Ward, H. H., Wandinger-Ness, A., Miller, W. M. & Wertheim, J. A., Aug 10 2015, In : Journal of Visualized Experiments. 2015, 102, p. 1-9 9 p., e53271.

Research output: Contribution to journal › Article

12 Scopus citations

Human megakaryocyte progenitors derived from hematopoietic stem cells of normal individuals are MHC class II-expressing professional APC that enhance Th17 and Th1/Th17 responses

Finkielsztein, A., Schlinker, A. C., Zhang, L., Miller, W. M. & Datta, S. K., Jan 1 2015, In : Immunology Letters. 163, 1, p. 84-95 12 p.

Research output: Contribution to journal › Article

11 Scopus citations

Optimization and critical evaluation of decellularization strategies to develop renal extracellular matrix scaffolds as biological templates for organ engineering and transplantation

Caralt, M., Uzarski, J. S., Iacob, S., Obergfell, K. P., Berg, N., Bijonowski, B. M., Kiefer, K. M., Ward, H. H., Wandinger-Ness, A., Miller, W. M., Zhang, Z. J., Abecassis, M. M. & Wertheim, J. A., Jan 1 2015, In : American Journal of Transplantation. 15, 1, p. 64-75 12 p.

Research output: Contribution to journal › Article

106 Scopus citations

Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration

Schlinker, A. C., Radwanski, K., Wegener, C., Min, K. & Miller, W. M., Apr 1 2015, In : Biotechnology and Bioengineering. 112, 4, p. 788-800 13 p.

Research output: Contribution to journal › Article

18 Scopus citations

2014

Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiation

Duncan, M. T., Shin, S., Wu, J. J., Mays, Z., Weng, S., Bagheri, N., Miller, W. M. & Shea, L. D., Oct 2014, In : Biotechnology and Bioengineering. 111, 10, p. 2082-2094 13 p.

Research output: Contribution to journal › Article

6 Scopus citations

2013

Administration of nicotinamide does not increase platelet levels in mice

Konieczna, I. M., Panuganti, S., DeLuca, T. A., Papoutsakis, E. T., Eklund, E. A. & Miller, W. M., Mar 1 2013, In : Blood Cells, Molecules, and Diseases. 50, 3, p. 171-176 6 p.

Research output: Contribution to journal › Article

6 Scopus citations

Synergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA

Ojima, Y., Duncan, M. T., Nurhayati, R. W., Taya, M. & Miller, W. M., Aug 15 2013, In : Experimental Cell Research. 319, 14, p. 2205-2215 11 p.

Research output: Contribution to journal › Article

13 Scopus citations

Three-stage Ex vivo expansion of high-ploidy megakaryocytic cells: Toward large-scale platelet production

Panuganti, S., Schlinker, A. C., Lindholm, P. F., Papoutsakis, E. T. & Miller, W. M., Apr 1 2013, In : Tissue Engineering - Part A. 19, 7-8, p. 998-1014 17 p.

Research output: Contribution to journal › Article

37 Scopus citations

2012

Energy, Water and Fish: Biodiversity Impacts of Energy-Sector Water Demand in the United States Depend on Efficiency and Policy Measures

McDonald, R. I., Olden, J. D., Opperman, J. J., Miller, W. M., Fargione, J., Revenga, C., Higgins, J. V. & Powell, J., Nov 21 2012, In : PloS one. 7, 11, e50219.

Research output: Contribution to journal › Article

18 Scopus citations

Proposed megakaryocytic regulon of p53: The genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation

Apostolidis, P. A., Lindsey, S., Miller, W. M. & Papoutsakis, E. T., Jun 1 2012, In : Physiological genomics. 44, 12, p. 638-650 13 p.

Research output: Contribution to journal › Article

19 Scopus citations

Role of tumor suppressor p53 in megakaryopoiesis and platelet function

Apostolidis, P. A., Woulfe, D. S., Chavez, M., Miller, W. M. & Papoutsakis, E. T., Feb 2012, In : Experimental Hematology. 40, 2, p. 131-142.e4

Research output: Contribution to journal › Article

22 Scopus citations

2010

Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential

Panuganti, S., Papoutsakis, E. T. & Miller, W. M., Oct 2010, In : Cytotherapy. 12, 6, p. 767-782 16 p.

Research output: Contribution to journal › Article

10 Scopus citations

2009

Cholesterol supplementation during production increases the infectivity of retroviral and lentiviral vectors pseudotyped with the vesicular stomatitis virus glycoprotein (VSV-G)

Chen, Y., Ott, C. J., Townsend, K., Subbaiah, P., Aiyar, A. & Miller, W. M., May 15 2009, In : Biochemical Engineering Journal. 44, 2-3, p. 199-207 9 p.

Research output: Contribution to journal › Article

13 Scopus citations

Effects of supported lipid monolayer fluidity on the adhesion of hematopoietic progenitor cell lines to fibronectin-derived peptide ligands for α5β1 and α4β1 integrins

Garcia, A. S., Dellatore, S. M., Messersmith, P. B. & Miller, W. M., Mar 3 2009, In : Langmuir. 25, 5, p. 2994-3002 9 p.

Research output: Contribution to journal › Article

18 Scopus citations

Energy sprawl or energy efficiency: Climate policy impacts on natural habitat for the United States of America

McDonald, R. I., Fargione, J., Kiesecker, J., Miller, W. M. & Powell, J., Aug 26 2009, In : PloS one. 4, 8, e6802.

Research output: Contribution to journal › Article

199 Scopus citations

Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD⁺ levels and SIRT inhibition

Giammona, L. M., Panuganti, S., Kemper, J. M., Apostolidis, P. A., Lindsey, S., Papoutsakis, E. T. & Miller, W. M., Nov 2009, In : Experimental Hematology. 37, 11, p. 1340-1352.e3

Research output: Contribution to journal › Article

31 Scopus citations

2008

Gene Ontology-driven transcriptional analysis of CD34⁺ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis

Fuhrken, P. G., Chen, C., Apostolidis, P. A., Wang, M., Miller, W. M. & Papoutsakis, E. T., Apr 22 2008, In : Physiological genomics. 33, 2, p. 159-169 11 p.

Research output: Contribution to journal › Article

21 Scopus citations

Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis

Fuhrken, P. G., Apostolidis, P. A., Lindsey, S., Miller, W. M. & Papoutsakis, E. T., Jun 6 2008, In : Journal of Biological Chemistry. 283, 23, p. 15589-15600 12 p.

Research output: Contribution to journal › Article

29 Scopus citations

2007

A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis

Chen, C., Fuhrken, P. G., Huang, L. T., Apostolidis, P., Wang, M., Paredes, C. J., Miller, W. M. & Papoutsakis, E. T., Oct 22 2007, In : BMC Genomics. 8, 384.

Research output: Contribution to journal › Article

16 Scopus citations

Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation

Fuhrken, P. G., Chen, C., Miller, W. M. & Papoutsakis, E. T., Mar 2007, In : Experimental Hematology. 35, 3, p. 476-489.e23

Research output: Contribution to journal › Article

37 Scopus citations

Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes

Huang, L. T., Paredes, C. J., Papoutsakis, E. T. & Miller, W. M., Sep 19 2007, In : Physiological genomics. 31, 1, p. 114-125 12 p.

Research output: Contribution to journal › Article

3 Scopus citations

Mussel-inspired surface chemistry for multifunctional coatings

Lee, H., Dellatore, S. M., Miller, W. M. & Messersmith, P. B., Oct 19 2007, In : Science. 318, 5849, p. 426-430 5 p.

Research output: Contribution to journal › Article

5651 Scopus citations

Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles

Pascoe, D. E., Arnott, D., Papoutsakis, E. T., Miller, W. M. & Andersen, D. C., Oct 1 2007, In : Biotechnology and Bioengineering. 98, 2, p. 391-410 20 p.

Research output: Contribution to journal › Article

55 Scopus citations

Surface presentation of bioactive ligands in a nonadhesive background using DOPA-tethered biotinylated poly(ethylene glycol)

Gunawan, R. C., King, J. A., Lee, B. P., Messersmith, P. B. & Miller, W. M., Oct 9 2007, In : Langmuir. 23, 21, p. 10635-10643 9 p.

Research output: Contribution to journal › Article

36 Scopus citations

2006

Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes

Giammona, L. M., Fuhrken, P. G., Papoutsakis, E. T. & Miller, W. M., Nov 1 2006, In : British Journal of Haematology. 135, 4, p. 554-566 13 p.

Research output: Contribution to journal › Article

57 Scopus citations

2005

Effects of NHE1 expression level on CHO cell responses to environmental stress

Abston, L. R. & Miller, W. M., Mar 1 2005, In : Biotechnology Progress. 21, 2, p. 562-567 6 p.

Research output: Contribution to journal › Article

1 Scopus citations

Transduction efficiency of pantropic retroviral vectors is controlled by the envelope plasmid to vector plasmid ratio

Chen, Y., Miller, W. M. & Aiyar, A., Jan 1 2005, In : Biotechnology Progress. 21, 1, p. 274-282 9 p.

Research output: Contribution to journal › Article

5 Scopus citations

2004

Actin Re-Distribution in Response to Hydrogen Peroxide in Airway Epithelial Cells

Boardman, K. C., Aryal, A. M., Miller, W. M. & Waters, C. M., Apr 1 2004, In : Journal of Cellular Physiology. 199, 1, p. 57-66 10 p.

Research output: Contribution to journal › Article

43 Scopus citations

Lipopeptides incorporated into supported phospholipid monolayers have high specific activity at low incorporation levels

Jensen, T. W., Hu, B. H., Delatore, S. M., Garcia, A. S., Messersmith, P. B. & Miller, W. M., Nov 24 2004, In : Journal of the American Chemical Society. 126, 46, p. 15223-15230 8 p.

Research output: Contribution to journal › Article

34 Scopus citations

2003

Small increases in pH enhance retroviral vector transduction efficiency of NIH-3T3 cells

Jensen, T. W., Chen, Y. & Miller, W. M., Jan 1 2003, In : Biotechnology Progress. 19, 1, p. 216-223 8 p.

Research output: Contribution to journal › Article

6 Scopus citations

2002

Characterization of hybridoma cell responses to elevated pCO₂ and osmolality: Intracellular pH, cell size, apoptosis, and metabolism

DeZengotita, V. M., Schmelzer, A. E. & Miller, W. M., Feb 15 2002, In : Biotechnology and Bioengineering. 77, 4, p. 369-380 12 p.

Research output: Contribution to journal › Article

72 Scopus citations

Continuous exposure of airway epithelial cells to hydrogen peroxide: Protection by KGF

Chapman, K. E., Waters, C. M. & Miller, W. M., Jun 13 2002, In : Journal of Cellular Physiology. 192, 1, p. 71-80 10 p.

Research output: Contribution to journal › Article

28 Scopus citations

Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation

Hevehan, D. L., Miller, W. M. & Papoutsakis, E. T., Mar 1 2002, In : Blood. 99, 5, p. 1627-1637 11 p.

Research output: Contribution to journal › Article

46 Scopus citations

Effects of osmoprotectant compounds on NCAM polysialylation under hyperosmotic stress and elevated pCO₂

Schmelzer, A. E. & Miller, W. M., Feb 15 2002, In : Biotechnology and Bioengineering. 77, 4, p. 359-368 10 p.

Research output: Contribution to journal › Article

16 Scopus citations

Higher pH promotes megakaryocytic maturation and apoptosis

Yang, H., Miller, W. M. & Papoutsakis, E. T., Jan 1 2002, In : Stem Cells. 20, 4, p. 320-328 9 p.

Research output: Contribution to journal › Article

45 Scopus citations

Hyperosmotic stress and elevated pCO₂ alter monoclonal antibody charge distribution and monosaccharide content

Schmelzer, A. E. & Miller, W. M., Apr 22 2002, In : Biotechnology Progress. 18, 2, p. 346-353 8 p.

Research output: Contribution to journal › Article

48 Scopus citations

Selected amino acids protect hybridoma and CHO cells from elevated carbon dioxide and osmolality

DeZengotita, V. M., Abston, L. R., Schmelzer, A. E., Shaw, S. & Miller, W. M., Jun 30 2002, In : Biotechnology and Bioengineering. 78, 7, p. 741-752 12 p.

Research output: Contribution to journal › Article

37 Scopus citations

2001

Model-based estimation of myeloid hematopoietic progenitor cells in ex vivo cultures for cell and gene therapies

Yang, H., Papoutsakis, E. T. & Miller, W. M., Jan 7 2001, In : Biotechnology and Bioengineering. 72, 2, p. 144-155 12 p.

Research output: Contribution to journal › Article

4 Scopus citations

Modeling pO₂ distributions in the bone marrow hematopoietic compartment. I. Krogh's model

Chow, D. C., Wenning, L. A., Miller, W. M. & Papoutsakis, E. T., Jan 1 2001, In : Biophysical Journal. 81, 2, p. 675-684 10 p.

Research output: Contribution to journal › Article

184 Scopus citations

Modeling pO₂ distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models

Chow, D. C., Wenning, L. A., Miller, W. M. & Papoutsakis, E. T., Jan 1 2001, In : Biophysical Journal. 81, 2, p. 685-696 12 p.

Research output: Contribution to journal › Article

222 Scopus citations

Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes

Mostafa, S. S., Papoutsakis, E. T. & Miller, W. M., Jul 12 2001, In : Experimental Hematology. 29, 7, p. 873-883 11 p.

Research output: Contribution to journal › Article

43 Scopus citations